High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity.

abstract：BACKGROUND:Hepatic arterioportal shunt (A-P shunt) is defined as the direct blood flow established between hepatic artery and portal venous system; it is frequently observed in patients with hepatocellular carcinoma (HCC). Clinically, it is important to diagnose HCC associated A-P shunts, as it may impact the treatment...

journal_title：BMC gastroenterology

authors： Wu H,Zhao W,Zhang J,Han J,Liu S

更新日期：2018-11-12 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) is a chronic complex disease of the gastrointestinal tract. Patients with IBD can experience a wide range of symptoms, but the pathophysiological mechanisms that cause these individual differences in clinical presentation remain largely unknown. In consequence, IBD is current...

journal_title：BMC gastroenterology

authors： Imhann F,Van der Velde KJ,Barbieri R,Alberts R,Voskuil MD,Vich Vila A,Collij V,Spekhorst LM,Van der Sloot KWJ,Peters V,Van Dullemen HM,Visschedijk MC,Festen EAM,Swertz MA,Dijkstra G,Weersma RK

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:The nuclear protein high-mobility group box 1 (HMGB1) is a key trigger for the inflammatory reaction during liver ischemia reperfusion injury (IRI). Hydrogen treatment was recently associated with down-regulation of the expression of HMGB1 and pro-inflammatory cytokines during sepsis and myocardial IRI, but ...

journal_title：BMC gastroenterology

authors： Liu Y,Yang L,Tao K,Vizcaychipi MP,Lloyd DM,Sun X,Irwin MG,Ma D,Yu W

更新日期：2014-01-12 00:00:00

abstract：BACKGROUND:Patients with advanced cirrhosis of the liver typically display circulatory disturbance. Haemodynamic management may be critical for avoiding and treating functional renal failure in such patients. This study investigated the effects of plasma expansion with hyperoncotic albumin solution and the role of stat...

journal_title：BMC gastroenterology

authors： Umgelter A,Wagner K,Reindl W,Nurtsch N,Huber W,Schmid RM

更新日期：2008-08-27 00:00:00

abstract：BACKGROUND:Infection is one of the important causes of death in patients with severe acute pancreatitis (SAP), but the bacterial spectrum and antibiotic resistance are constantly changing. Making good use of antibiotics and controlling multi-drug-resistant (MDR) bacterial infections are of vital importance in improving...

journal_title：BMC gastroenterology

authors： Fan N,Hu Y,Shen H,Liu S,Zhao G,Sun L,Li C,Zhao X,Li Y,Wang J,Cui Y

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Oral anticoagulants like the coumarin derivatives are characterised by a particularly narrow therapeutic range. Any interfering co-medication can pose a challenge to establishing a stable anticoagulant dosage regimen and thus present a serious risk for the patient. Here we describe two cases of patients on a...

journal_title：BMC gastroenterology

authors： Enderle C,Müller W,Grass U

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The majority of colonic obstructions result from colorectal cancer. However, malignancies of extra-colonic origin can also disrupt colorectal patency, and the efficacy of self-expanding metal stents (SEMS) insertion as a bridge to surgery in these patients are still in debate. The aim of this study is to eva...

journal_title：BMC gastroenterology

authors： Kim EJ,Han SH,Kim KO,Chung JW,Park DK,Kwon KA,Kim JH

更新日期：2020-04-19 00:00:00

abstract：BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive carcinomas of the gastrointestinal tract. We assessed the relevance of Slug in measuring the invasive potential of ESCC cells in vitro and in vivo in immunodeficient mice. METHODS:We utilized RNA interference to knockdown Slug gene expr...

journal_title：BMC gastroenterology

authors： Tang P,Yu Z,Zhang K,Wang Y,Ma Z,Zhang S,Chen D,Zhou Y

更新日期：2011-05-20 00:00:00

abstract：BACKGROUND:Green tea has shown the role of chemoprevention for cancer. Recently, several studies suggested that green tea intake may have effect on esophageal cancer risk, whereas the results were inconsistent. METHODS:We performed a meta-analysis of all English and Chinese language studies of green tea consumption an...

journal_title：BMC gastroenterology

authors： Zheng P,Zheng HM,Deng XM,Zhang YD

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:This case seeks to highlight to endoscopists a rare benign disorder that may be encountered during endoscopy. Clinicians may be tempted to biopsy, which could lead to a catastrophic gastrointestinal haemorrhage. CASE PRESENTATION:A 66-year-old asymptomatic Caucasian male was referred for colonoscopy with a ...

journal_title：BMC gastroenterology

authors： Abeysekera KWM,Pearl DS,Burn P,Lowe A

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Trends in gastroenteritis-associated mortality are changing over time with development of antibiotic resistant strains of certain pathogens, improved diagnostic methods, and changing healthcare. In 1999, ICD-10 coding was introduced for mortality records which can also affect trends. We assess trends in gast...

journal_title：BMC gastroenterology

authors： Jagai JS,Smith GS,Schmid JE,Wade TJ

更新日期：2014-12-10 00:00:00

abstract：BACKGROUND:Delayed gastric emptying (DGE) is one of the most frequent complications after pancreaticoduodenectomy (PD). This meta-analysis aimed to evaluate the effect of antecolic versus retrocolic reconstruction of gastro/duodenojejunostomy on DGE after PD. METHODS:Randomized controlled trials (RCTs) comparing antec...

journal_title：BMC gastroenterology

authors： Zhou Y,Lin J,Wu L,Li B,Li H

更新日期：2015-06-16 00:00:00

abstract：BACKGROUND:Endoscopic treatments, such as endoscopic submucosal dissection (ESD) and laparoscopic gastrectomy, are increasingly used to treat a subset of patients with early gastric cancer (EGC). To achieve successful outcomes, it is very important to accurately determine the lateral extent of the tumor. Therefore, we ...

journal_title：BMC gastroenterology

authors： Lee BE,Kim GH,Park DY,Kim DH,Jeon TY,Park SB,You HS,Ryu DY,Kim DU,Song GA

更新日期：2010-08-23 00:00:00

abstract：BACKGROUND:Stercoral colitis is a rare inflammatory process involving the colonic wall secondary to fecal impaction with high morbidity and mortality; especially if complicated with ischemic colitis, stercoral ulcer formation and subsequent perforation. There are several case reports published on abdominal perforation ...

journal_title：BMC gastroenterology

authors： Naseer M,Gandhi J,Chams N,Kulairi Z

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. The present study directly assessed the clinical translatability of the model by head-to-head compar...

journal_title：BMC gastroenterology

authors： Hansen HH,Ægidius HM,Oró D,Evers SS,Heebøll S,Eriksen PL,Thomsen KL,Bengtsson A,Veidal SS,Feigh M,Suppli MP,Knop FK,Grønbæk H,Miranda D,Trevaskis JL,Vrang N,Jelsing J,Rigbolt KTG

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:Hepatic artery dissection after liver transplantation is an uncommon morbidity. The onset mechanism and management for this disorder remain unclear. The present report describes the cases of two patients with hepatic artery dissection after living-donor liver transplantation (LDLT) with simultaneous splenect...

journal_title：BMC gastroenterology

authors： Shimata K,Sugawara Y,Irie T,Sambommatsu Y,Kadohisa M,Ibuki S,Kawabata S,Isono K,Honda M,Yamamoto H,Hibi T

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:Benign biliary strictures may be a consequence of surgical procedures, chronic pancreatitis or iatrogenic injuries to the ampulla. Stents are increasingly being used for this indication, however it is not completely clear which stent type should be preferred. METHODS:A systematic review on stent placement f...

journal_title：BMC gastroenterology

authors： van Boeckel PG,Vleggaar FP,Siersema PD

更新日期：2009-12-17 00:00:00

abstract：BACKGROUND:Adult lactase non-persistence (LNP) is due to low lactase expression, resulting in lactose malabsorption (LM). LNP is a genetic trait, but is typically determined by LM markers including breath H2, blood glucose, and urinary galactose after a lactose tolerance test. Known validity of these markers using milk...

journal_title：BMC gastroenterology

authors： Shrestha A,Barnett MPG,Perry JK,Cameron-Smith D,Milan AM

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a vasculitis that mostly occurs in young children. Adult-onset KD (AKD) is rare and often misdiagnosed. Here we report a rare case of KD with cholestasis as principal symptom. CASE PRESENTATION:A 43-year-old caucasian man was admitted to our hosp...

journal_title：BMC gastroenterology

authors： Gallerani M,Pala M,Fabbian F,De Giorgi A

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:Gastrointestinal fistula (GIF) in severe acute pancreatitis (SAP) is considered as a sparse episode and studied sporadically in the literature. There is paucity of data on the prediction of the effect on risk of GIF in patient with SAP. This study was aimed to investigate risk factors related to GIF in the d...

journal_title：BMC gastroenterology

authors： Hua Z,Su Y,Huang X,Zhang K,Yin Z,Wang X,Liu P

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND:Glycoprotein 2 (GP2) was discovered as the major autoantigen of Crohn's disease (CD)-specific pancreatic autoantibodies (PAB). We investigated anti-GP2 IgA and IgG antibodies as novel serological parameters in CD and assessed their association with distinct disease phenotypes. METHODS:Anti-GP2 and anti-Sacc...

journal_title：BMC gastroenterology

authors： Bogdanos DP,Roggenbuck D,Reinhold D,Wex T,Pavlidis P,von Arnim U,Malfertheiner P,Forbes A,Conrad K,Laass MW

更新日期：2012-08-06 00:00:00

abstract：BACKGROUNDS:There is a discrepancy between west and east on the relationship between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD). This study aimed to find out the possible reason for this and to clarify the association between NAFLD and CKD by analyzing two population-based datasets from ...

journal_title：BMC gastroenterology

authors： Zhang M,Lin S,Wang MF,Huang JF,Liu SY,Wu SM,Zhang HY,Wu ZM,Liu WY,Zhang DC,Hao CM,Zhu YY,Zheng MH,Wang XZ

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:The elderly population presents higher morbidity of H. pylori associated diseases in proximal stomach. The specific pathogenesis and mechanism have not been clearly addressed. The gastric environment for H. pylori colonization is dynamic with increasing age. The aim of present study is to investigate the cor...

journal_title：BMC gastroenterology

authors： Shi H,Xiong H,Qian W,Lin R

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:There is insufficient evidence on the effectiveness of acupuncture for irritable bowel syndrome (IBS) for conclusions to be drawn. Given the current interest in acupuncture by patients, it is in the public interest to establish more rigorous evidence. Building on the positive findings from a pilot study, in ...

journal_title：BMC gastroenterology

authors： MacPherson H,Bland M,Bloor K,Cox H,Geddes D,Kang'ombe A,Reynolds J,Stamuli E,Stuardi T,Tilbrook H,Torgerson D,Whorwell P

更新日期：2010-06-17 00:00:00

abstract：BACKGROUND:Inflammation and immune activation have repeatedly been suggested as pathogentic factors in irritable bowel syndrome (IBS). The driving force for immune activation in IBS remains unknown. The aim of our study was to find out if the obligate intracellular pathogen Chlamydia could be involved in the pathogenes...

journal_title：BMC gastroenterology

authors： Dlugosz A,Törnblom H,Mohammadian G,Morgan G,Veress B,Edvinsson B,Sandström G,Lindberg G

更新日期：2010-02-16 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is a risk factor for colorectal neoplasms. Our goal is to explore the relationship between NAFLD and colorectal cancer (CRC) and to analyze potential indicators for screening CRC in NAFLD based on clinical big data. METHODS:Demographic information and routine clinica...

journal_title：BMC gastroenterology

authors： Yang R,Chen Y,Chen X

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:HBV and HCV reactivation have been widely reported in patients undergoing immunosuppressive therapy (IT); however, few data are available on the risk of reactivation in patients with psoriasis receiving IT. The aim of our study was to assess the prevalence of HBV and HCV infection in patients with psoriasis ...

journal_title：BMC gastroenterology

authors： Morisco F,Guarino M,La Bella S,Di Costanzo L,Caporaso N,Ayala F,Balato N

更新日期：2014-12-19 00:00:00

abstract：BACKGROUND:Undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) is an extremely uncommon pancreatic neoplasm that comprises less than 1% of all exocrine pancreatic tumors. To date, cases and data from whole-exome sequencing (WES) analysis have been reported by specific studies. We report a case of pancr...

journal_title：BMC gastroenterology

authors： Yang G,Yin J,Ou K,Du Q,Ren W,Jin Y,Peng L,Yang L

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Compared with biofluids, target tissues and organs more directly reflect the pathophysiological state of a disease process. In this study, a D-galactosamine (GalN) / lipopolysaccharide (LPS)-induced mouse model was constructed to investigate metabonomics of liver tissue and directly characterize metabolic ch...

journal_title：BMC gastroenterology

authors： Feng B,Wu S,Liu F,Gao Y,Dong F,Wei L

更新日期：2013-04-29 00:00:00

abstract：BACKGROUND:A marked expansion of the connective tissue population and an abnormal deposition of extracellular matrix proteins are hallmarks of chronic and acute injuries to liver tissue. Liver connective tissue cells, also called stellate cells, derived from fibrotic liver have been thoroughly characterized and corresp...

journal_title：BMC gastroenterology

authors： Geremias AT,Carvalho MA,Borojevic R,Monteiro AN

更新日期：2004-12-03 00:00:00