Abstract:
BACKGROUND:The majority of colonic obstructions result from colorectal cancer. However, malignancies of extra-colonic origin can also disrupt colorectal patency, and the efficacy of self-expanding metal stents (SEMS) insertion as a bridge to surgery in these patients are still in debate. The aim of this study is to evaluate the efficacy of endoscopic stenting as a bridge to surgery (BTS) for extra-colonic malignancy (ECM)-induced colonic obstruction. METHODS:Thirty-three patients with colonic obstruction due to ECM who received self-expanding metal stents (SEMS) insertion at a single academic tertiary medical center between 2004 and 2015 were included. The purpose of SEMS insertion was determined based on whether the patient's medical records indicated any surgical plans before SEMS insertion. Technical success was defined as a patent SEMS covering the entire length of the obstruction. Bridging success was defined as elective surgical procedures after the first SEMS insertion. RESULTS:Among the 33 patients who underwent SEMS insertion for colorectal obstruction due to ECM, nine underwent SEMS as a BTS. Technical success was achieved in 100% (9/9). Seven patients underwent elective surgery after successful decompression with the first SEMS, and the bridging success rate was 77.8% (7/9). Two patients needed secondary stent insertion before elective surgery. However, none of them required emergent surgery. No major complications occurred, including death related to colorectal endoscopic procedures, perforation, or bleeding. CONCLUSION:SEMS insertion as a BTS is a good treatment option to avoid emergent surgery in patients with colonic obstruction caused by extra-colonic malignancy.
journal_name
BMC Gastroenteroljournal_title
BMC gastroenterologyauthors
Kim EJ,Han SH,Kim KO,Chung JW,Park DK,Kwon KA,Kim JHdoi
10.1186/s12876-020-01273-4subject
Has Abstractpub_date
2020-04-19 00:00:00pages
117issue
1issn
1471-230Xpii
10.1186/s12876-020-01273-4journal_volume
20pub_type
杂志文章abstract:BACKGROUND:The gut microbiome is altered in Crohn's disease. Although individual taxa have been correlated with post-operative clinical course, global trends in microbial diversity have not been described in this context. METHODS:We collected mucosal biopsies from the terminal ileum and ascending colon during surgery ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-13-131
更新日期:2013-08-22 00:00:00
abstract:BACKGROUND:Compared with biofluids, target tissues and organs more directly reflect the pathophysiological state of a disease process. In this study, a D-galactosamine (GalN) / lipopolysaccharide (LPS)-induced mouse model was constructed to investigate metabonomics of liver tissue and directly characterize metabolic ch...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-13-73
更新日期:2013-04-29 00:00:00
abstract:BACKGROUND:Crystal storing histiocytosis is a rare disorder associated with monoclonal gammopathy. In this disease, monoclonal heavy and light chains accumulate in the lysosome of macrophages, leading to histiocytic reaction in different organs. It is secondary to the presence of a small B-cell clone, responsible for m...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01364-2
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:A tenth of patients with involuntary weight loss (IWL) have gastrointestinal cancer. Ferritin is the first parameter to be modified during the process leading to iron deficiency anaemia, therefore it should be the most sensitive. The aim of this study was to assess the ability of ferritin to rule out gastroi...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-86
更新日期:2012-07-09 00:00:00
abstract:BACKGROUND:We prepared an oral W/O microemulsion for the removal of colonic ammonia (ME-RCA). The effect of this microemulsion was influenced by the digestion process in the gastrointestinal tract. In this paper, we aim to show that stability was improved by using a microemulsion-based gel for the removal of colonic am...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-11-50
更新日期:2011-05-10 00:00:00
abstract:BACKGROUND:In Brazil, it is estimated that between 2.5 and 4.9% of the general population present anti-hepatitis C virus (HCV) antibodies, which corresponds to as many as 3.9 to 7.6 million chronic carriers. Chronic liver disease is associated with HCV infection in 20% to 58% of the Brazilian patients. The objective of...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230x-2-18
更新日期:2002-08-08 00:00:00
abstract:BACKGROUND:Studies concerning clinical course and outcome of acute pancreatitis (AP) according to etiologies were rare, especially after year 2000. This study was designed to investigate the difference between the clinical course of alcoholic and biliary AP. METHODS:Of the 153 patients diagnosed as AP with a first att...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-015-0323-1
更新日期:2015-07-25 00:00:00
abstract:BACKGROUND:It is believed that inflammatory bowel diseases (IBD) result from an imbalance in the intestinal immune response towards the luminal microbiome. Dectin-1 is a widely expressed pattern recognition receptor that recognizes fungi and upon recognition it mediates cytokine responses and skewing of the adaptive im...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-33
更新日期:2012-04-16 00:00:00
abstract:BACKGROUND:Pancreatic duct disruption is a challenging condition leading to pancreatic juice leakage and consequently to pancreatic fluid collections. The manifestations of pancreatic main duct leak include pseudocysts, walled-off necrosis, pancreatic fistulas, ascites, pleural and pericardial effusions. Pseudocyst for...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0781-3
更新日期:2018-04-23 00:00:00
abstract:BACKGROUND:Efforts to identify cell sources and approaches for cell therapy of liver diseases are ongoing, taking into consideration the limits recognized for adult liver tissue and for other forms of stem cells. In the present study, we described the first procedure of via hepatic artery transplantation of human fetal...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-014-0204-z
更新日期:2014-12-04 00:00:00
abstract:BACKGROUND:Currently there is no disease-specific outcome measure to assess the health-related quality of life (HRQOL) of pediatric patients with Eosinophilic Esophagitis (EoE). Therefore, the objective of this qualitative study was to further develop and finalize the items and support the content validity for the new ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-135
更新日期:2012-09-25 00:00:00
abstract:BACKGROUND:Foreign body ingestion complicated by perforation of the digestive tract is a well-known occurrence. Contrary to this, perforation by fishbones has most often been described in South East Asian populations, and has the unusual characteristic of often being paucisymptomatic until secondary complications occur...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-14-167
更新日期:2014-09-27 00:00:00
abstract:BACKGROUND:Allergic proctocolitis (APC) in exclusively breast-fed infants is caused by food proteins, deriving from maternal diet, transferred through lactation. In most cases a maternal cow milk-free diet leads to a prompt resolution of rectal bleeding, while in some patients a multiple food allergy can occur. The aim...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-11-82
更新日期:2011-07-16 00:00:00
abstract:BACKGROUND:Percutaneous Endoscopic Gastrostomy (PEG) feeding tubes are frequently placed in patients to provide enteral nutrition. We report a case of a complete rupture of a PEG tube intra-abdominally with associated peritonitis after more than a month of PEG placement and utilization. To our knowledge, this is a very...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01218-x
更新日期:2020-03-30 00:00:00
abstract:BACKGROUND:Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. The present study directly assessed the clinical translatability of the model by head-to-head compar...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01356-2
更新日期:2020-07-06 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-13-122
更新日期:2013-07-30 00:00:00
abstract:BACKGROUND:Anal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for overall survival. The aim of this study was to evaluate the association of HPV and HIV status, p16 expression level and TP53 mutations with the absence ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0758-2
更新日期:2018-02-21 00:00:00
abstract:BACKGROUND:Irritable bowel syndrome (IBS) is a very common functional bowel disorder. However, the difference of depression and anxiety comorbidities among different IBS subtypes is still not well evaluated. This study aims to investigate the difference in the level and prevalence of depression and anxiety among health...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01593-5
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC). Nonetheless, the relevance of faecal calprotectin (FC) measurement during granulomonocytapheresis (GMA) for UC has not yet been ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0853-4
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Several association studies with small sample sizes of two SNPs in IL28BB (rs12979860 and rs8099917) showed inconsistent results, so in this study, we aim to evaluate the association between the two SNPs and infection susceptibility of Hepatitis B Virus (HBV) in Asian population, especially in Chinese popula...
journal_title:BMC gastroenterology
pub_type: 杂志文章,meta分析
doi:10.1186/s12876-015-0286-2
更新日期:2015-05-12 00:00:00
abstract:BACKGROUND:The use of thickeners is a standard therapy for decreasing episodes of regurgitation or vomiting in infants. However, it remains to be investigated whether thickener is effective for vomiting and/or chronic respiratory symptoms in children with cerebral palsy. METHODS:We enrolled 18 neurologically impaired ...
journal_title:BMC gastroenterology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-230X-8-11
更新日期:2008-04-16 00:00:00
abstract:BACKGROUND:A novel in vitro system was employed to investigate liver tissue respiration (mitochondrial O2 consumption) in mice treated with concanavalin A (Con A). This study aimed to investigate hepatocyte bioenergetics in this well-studied hepatitis model. METHODS:C57Bl/6 and C57Bl/6 IFN-γ-/- mice were injected intr...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-13-6
更新日期:2013-01-12 00:00:00
abstract:BACKGROUND:Gastric ulcers are a frequent problem in the United States. Proton pump inhibitors have been shown to increase healing rates and improve clinical symptoms. The objective of this study is to compare gastric ulcer healing rates for patients treated with a proton pump inhibitor (PPI) (omeprazole, rabeprazole, p...
journal_title:BMC gastroenterology
pub_type: 杂志文章,meta分析
doi:10.1186/1471-230x-2-17
更新日期:2002-07-15 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230x-1-5
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:We examined the intrinsic hepatic innervation after partial hepatectomy (PH) in rats and the presence and pattern of neural sprouting in regenerating liver. METHODS:Male Wistar rats (age 9-13 weeks-w, weight 204-356 g), were submitted to two-thirds PH. Rats were sacrificed at postoperative days (d) 1, 3, 5,...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-014-0202-1
更新日期:2014-11-25 00:00:00
abstract:BACKGROUND:Recent improvements in stone extraction implements and apparatus have lessened the complexity of the endoscopic bile duct stone treatment. However, despite confirmation of complete removal, cases of residual stones have been reported, which can result in recurrent biliary symptoms, cholangitis, and pancreati...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01428-3
更新日期:2020-08-24 00:00:00
abstract:BACKGROUND:The prevalence of esophageal neoplasia in head and neck (H&N) cancer patients is not low; however, routine esophageal surveillance is not included in staging of newly-diagnosed H&N cancers. We aimed to investigate the risk factors for synchronous esophageal neoplasia and the impact of endoscopy on management...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-13-154
更新日期:2013-10-25 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-015-0241-2
更新日期:2015-02-15 00:00:00
abstract:BACKGROUND:Vitamin K deficiency results in serious coagulation dysfunction, but hemorrhagic shock is rare. Herein, we describe a case of vitamin K deficiency and abnormality in the path of the intercostal artery, the combination of which led to hemorrhagic shock. CASE PRESENTATION:An 83-year-old woman was hospitalized...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-019-0978-0
更新日期:2019-04-18 00:00:00
abstract:BACKGROUND:There is insufficient evidence on the effectiveness of acupuncture for irritable bowel syndrome (IBS) for conclusions to be drawn. Given the current interest in acupuncture by patients, it is in the public interest to establish more rigorous evidence. Building on the positive findings from a pilot study, in ...
journal_title:BMC gastroenterology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-230X-10-63
更新日期:2010-06-17 00:00:00