Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas harboring KRAS and BRCA mutations: case report and whole exome sequencing analysis.

abstract：BACKGROUND:Bowel symptoms are considered indicators of the presence of colorectal cancer and other bowel diseases. Self administered questionnaires that elicit information about lower bowel symptoms have not been assessed for reliability, although this has been done for upper bowel symptoms. Our aim was to develop a se...

journal_title：BMC gastroenterology

authors： Adelstein BA,Irwig L,Macaskill P,Katelaris PH,Jones DB,Bokey L

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The use of immune-checkpoint inhibitors in cancer treatment has become increasingly common, resulting in an increase in the incidence of related side effects. Diarrhoea and colitis have been previously documented as gastrointestinal tract-related side effects of immune-checkpoint inhibitors. Although PD-1/PD...

journal_title：BMC gastroenterology

authors： Yamauchi R,Araki T,Mitsuyama K,Tokito T,Ishii H,Yoshioka S,Kuwaki K,Mori A,Yoshimura T,Tsuruta O,Torimura T

更新日期：2018-08-31 00:00:00

abstract：BACKGROUND:Stress is a common contributing factor for irritable bowel syndrome (IBS). This study was to evaluate the efficacy of the centralized health education program in improving the quality of life (QOL) of middle school students with IBS who experienced the Wenchuan earthquake on May 12, 2008. METHODS:A multi-ce...

journal_title：BMC gastroenterology

authors： Zheng SC,Gong H,Wang YP,Zhang Q,Wang LL,Liao XF,He DW,Wu J

更新日期：2018-07-27 00:00:00

abstract：BACKGROUND:Symptoms suggestive of functional dyspepsia (FD) and irritable bowel syndrome (IBS) frequently overlap with those of gastroesophageal reflux disease. Despite the high prevalence of symptomatic overlap, the underlying etiology remains poorly defined. We assessed the correlation of symptomatic relief and healt...

journal_title：BMC gastroenterology

authors： Mönnikes H,Schwan T,van Rensburg C,Straszak A,Theek C,Lühmann R,Sander P,Tholen A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The emergence of multidrug-resistant (MDR) Escherichia coli (E. coli), particularly E. coli sequence type ST131, is becoming a global concern. Commensal bacteria, an important reservoir of antibiotic resistance genes, facilitate the spread of such genes to pathogenic bacterial strains. The objective of the s...

journal_title：BMC gastroenterology

authors： Huang IF,Lee WY,Wang JL,Hung CH,Hu HH,Hung WY,Hung YJ,Chen WC,Shen YT,Cheng MF

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Carrageenan is a traditional ingredient that has been widely used in the food industry. In the present study, we propose a hypothesis that carrageenan is a conditional inflammatory agent. When the intestinal tract is in an "unhealthy" state such as that during bacterial infection or acute inflammation, carra...

journal_title：BMC gastroenterology

authors： Wu W,Wang F,Gao X,Niu T,Zhu X,Yan X,Chen H

更新日期：2016-03-25 00:00:00

abstract：BACKGROUND:Patients with advanced cirrhosis of the liver typically display circulatory disturbance. Haemodynamic management may be critical for avoiding and treating functional renal failure in such patients. This study investigated the effects of plasma expansion with hyperoncotic albumin solution and the role of stat...

journal_title：BMC gastroenterology

authors： Umgelter A,Wagner K,Reindl W,Nurtsch N,Huber W,Schmid RM

更新日期：2008-08-27 00:00:00

abstract：BACKGROUND:Advances in intensive care support such as therapeutic hypothermia or new liver assist devices have been the mainstay of treatment attempting to bridge the gap from acute liver failure to liver transplantation, but the efficacy of the available devices in reducing mortality has been questioned. To address th...

journal_title：BMC gastroenterology

authors： Thiel K,Schenk M,Etspüler A,Schenk T,Morgalla MH,Königsrainer A,Thiel C

更新日期：2011-07-14 00:00:00

abstract：BACKGROUND:Biliary atresia (BA) is a progressive inflammatory disorder of the extrahepatic bile ducts leading to the obliteration of bile flow. The purpose of this study was to determine serum adiponectin in BA patients and to investigate the relationship of adiponectin with clinical parameters and liver stiffness scor...

journal_title：BMC gastroenterology

authors： Honsawek S,Chayanupatkul M,Chongsrisawat V,Theamboonlers A,Praianantathavorn K,Udomsinprasert W,Vejchapipat P,Poovorawan Y

更新日期：2011-02-28 00:00:00

abstract：BACKGROUND:Stercoral colitis is a rare inflammatory process involving the colonic wall secondary to fecal impaction with high morbidity and mortality; especially if complicated with ischemic colitis, stercoral ulcer formation and subsequent perforation. There are several case reports published on abdominal perforation ...

journal_title：BMC gastroenterology

authors： Naseer M,Gandhi J,Chams N,Kulairi Z

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:The nuclear protein high-mobility group box 1 (HMGB1) is a key trigger for the inflammatory reaction during liver ischemia reperfusion injury (IRI). Hydrogen treatment was recently associated with down-regulation of the expression of HMGB1 and pro-inflammatory cytokines during sepsis and myocardial IRI, but ...

journal_title：BMC gastroenterology

authors： Liu Y,Yang L,Tao K,Vizcaychipi MP,Lloyd DM,Sun X,Irwin MG,Ma D,Yu W

更新日期：2014-01-12 00:00:00

abstract：BACKGROUND:Non-adherence to drug therapy is common in Inflammatory Bowel Disease (IBD). Patients' beliefs about treatment have an important influence on adherence. An in-depth understanding of this area is, therefore, important for patient-centred care. The aim of the study was to assess patients' perspectives and beli...

journal_title：BMC gastroenterology

authors： Hall NJ,Rubin GP,Hungin AP,Dougall A

更新日期：2007-06-08 00:00:00

abstract：BACKGROUND:Infection is one of the important causes of death in patients with severe acute pancreatitis (SAP), but the bacterial spectrum and antibiotic resistance are constantly changing. Making good use of antibiotics and controlling multi-drug-resistant (MDR) bacterial infections are of vital importance in improving...

journal_title：BMC gastroenterology

authors： Fan N,Hu Y,Shen H,Liu S,Zhao G,Sun L,Li C,Zhao X,Li Y,Wang J,Cui Y

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:To exam the biochemical, obstetric management and pregnancy outcome in women with intrahepatic cholestasis of pregnancy (ICP) and treatment with ursodeoxycholic acid (UDCA). METHODS:Pregnancy outcome in patients with ICP (N = 307) was studied and patients treated with UDCA (N = 208) vs. no UDCA were compare...

journal_title：BMC gastroenterology

authors： Joutsiniemi T,Timonen S,Linden M,Suvitie P,Ekblad U

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Coeliac disease is characterised by villous atrophy, which usually normalises after gluten withdrawal. Sometimes the revaluation of duodenal histology is required during follow-up, even if the methodology for comparing duodenal histology before and after introducing a gluten-free diet is not yet established....

journal_title：BMC gastroenterology

authors： Elli L,Zini E,Tomba C,Bardella MT,Bosari S,Conte D,Runza L,Roncoroni L,Ferrero S

更新日期：2015-10-14 00:00:00

abstract：BACKGROUND:Sclerosing encapsulating peritonitis (SEP) is a rare cause of small-bowel obstruction. The optimal treatment for this condition remains controversial. METHODS:In this study, we performed a retrospective analysis of the data of 44 patients who underwent surgery for SEP between December 2001 and 2008 at our h...

journal_title：BMC gastroenterology

authors： Li M,Zhu W,Li Y,Jiang J,Li J,Li N

更新日期：2014-11-25 00:00:00

abstract：BACKGROUND:MCAD-deficiency is the most common inborn error of fatty acid oxidation now included in many newborn screening programms using MS/MS. During prolonged catabolic episodes, patients may suffer from metabolic decompensation with dysfunction of liver, skeletal- and heart muscle as well as brain. In anabolism, ne...

journal_title：BMC gastroenterology

authors： Das AM,Drache S,Janzen N,Franke A

更新日期：2012-08-30 00:00:00

abstract：BACKGROUND:Gastric cancer can progress from a chronic inflammation of the gastric mucosa resulting from Helicobacter pylori infection that activates the inflammatory response of the host. Therefore, polymorphisms in genes involved in the inflammatory response, such as inducible nitric oxide synthase (NOS2), have been i...

journal_title：BMC gastroenterology

authors： Jorge YC,Duarte MC,Silva AE

更新日期：2010-06-17 00:00:00

abstract：BACKGROUND:Little data exists on the factors associated with health care seeking behaviour for primary symptoms of colorectal cancer (CRC). This study aimed to identify individual, provider and psychosocial factors associated with (i) ever seeking medical advice and (ii) seeking early medical advice for primary symptom...

journal_title：BMC gastroenterology

authors： Courtney RJ,Paul CL,Sanson-Fisher RW,Macrae FA,Attia J,McEvoy M

更新日期：2012-08-03 00:00:00

abstract：BACKGROUND:Benign biliary strictures may be a consequence of surgical procedures, chronic pancreatitis or iatrogenic injuries to the ampulla. Stents are increasingly being used for this indication, however it is not completely clear which stent type should be preferred. METHODS:A systematic review on stent placement f...

journal_title：BMC gastroenterology

authors： van Boeckel PG,Vleggaar FP,Siersema PD

更新日期：2009-12-17 00:00:00

abstract：BACKGROUND:A validated histopathological tool to precisely evaluate bowel fibrosis in patients with Crohn's disease is lacking. We attempted to establish a new index to quantify the severity of bowel fibrosis in patients with Crohn's disease-associated fibrostenosis. METHODS:We analyzed the histopathological data of 3...

journal_title：BMC gastroenterology

authors： Li XH,Fang ZN,Guan TM,Lin JJ,Sun CH,Huang SY,Mao R,Lu BL,Cao QH,Feng ST,Li ZP

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:We aimed to provide empirical evidence of how spectrum effects can affect the sensitivity of histological assessment of Helicobacter pylori infection, which may contribute to explain the heterogeneity in prevalence estimates across populations with expectedly similar prevalence. METHODS:Cross-sectional eval...

journal_title：BMC gastroenterology

authors： Lunet N,Peleteiro B,Carrilho C,Figueiredo C,Azevedo A

更新日期：2009-12-24 00:00:00

abstract：BACKGROUND:Intestinal metaplasia (IM) is an important precursor lesion in the development of gastric cancer (GC). The aim of this study was to investigate genetic factors previously linked to GC risk for their possible association with IM. A total of 18 polymorphisms in 14 candidate genes were evaluated in a Singapore-...

journal_title：BMC gastroenterology

authors： Zhu F,Loh M,Hill J,Lee S,Koh KX,Lai KW,Salto-Tellez M,Iacopetta B,Yeoh KG,Soong R,Singapore Gastric Cancer Consortium.

更新日期：2009-10-13 00:00:00

abstract：BACKGROUND:There is consistent evidence that 50% of patients with acute, steroid-resistant flare of ulcerative colitis (UC) may achieve remission and avoid colectomy if treated with cyclosporin (CsA). However, follow-up of the responders has shown that most of them relapse and need surgery shortly after the response. W...

journal_title：BMC gastroenterology

authors： Actis GC,Fadda M,David E,Sapino A

更新日期：2007-03-27 00:00:00

abstract：BACKGROUND:The clinical course of chronic pancreatitis is still unpredictable, which relates to the lack of the availability of a clinical classification. Therefore, patient populations cannot be compared, the course and the outcome of the disease remain undetermined in the individual patient, and treatment is not stan...

journal_title：BMC gastroenterology

authors： Büchler MW,Martignoni ME,Friess H,Malfertheiner P

更新日期：2009-12-14 00:00:00

abstract：BACKGROUND:Nodular lymphoid hyperplasia of gastrointestinal tract is a rare disorder, often associated with immunodeficiency syndromes. There are no published reports of its association with Helicobacter pylori infection. METHODS:From March 2005 till February 2010, we prospectively followed all patients with diffuse d...

journal_title：BMC gastroenterology

authors： Khuroo MS,Khuroo NS,Khuroo MS

更新日期：2011-04-11 00:00:00

abstract：BACKGROUND:The association between proinflammatory cytokine gene polymorphisms and gastric diseases related to Helicobacter pylori varies by population and geographic area.Our objective was to determine if the IL-1B -511 T>C and -31 C>T polymorphisms and H. pylori vacA genotypes are associated with risk of chronic gast...

journal_title：BMC gastroenterology

authors： Martínez-Carrillo DN,Garza-González E,Betancourt-Linares R,Mónico-Manzano T,Antúnez-Rivera C,Román-Román A,Flores-Alfaro E,Illades-Aguiar B,Fernández-Tilapa G

更新日期：2010-10-27 00:00:00

abstract：BACKGROUND:Recent improvements in stone extraction implements and apparatus have lessened the complexity of the endoscopic bile duct stone treatment. However, despite confirmation of complete removal, cases of residual stones have been reported, which can result in recurrent biliary symptoms, cholangitis, and pancreati...

journal_title：BMC gastroenterology

authors： Fujita A,Nakahara K,Michikawa Y,Morita R,Suetani K,Sato J,Igarashi Y,Araki R,Ikeda H,Matsunaga K,Watanabe T,Itoh F

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:In Brazil, it is estimated that between 2.5 and 4.9% of the general population present anti-hepatitis C virus (HCV) antibodies, which corresponds to as many as 3.9 to 7.6 million chronic carriers. Chronic liver disease is associated with HCV infection in 20% to 58% of the Brazilian patients. The objective of...

journal_title：BMC gastroenterology

authors： Brandão AB,Fuchs SC

更新日期：2002-08-08 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of liver diseases, ranging from pure steatosis to nonalcoholic steatohepatitis (NASH), and eventually to liver cirrhosis with its complications. Identifying advanced fibrosis in patients is crucial to evaluating prognosis and possible therapeu...

journal_title：BMC gastroenterology

authors： Raszeja-Wyszomirska J,Szymanik B,Ławniczak M,Kajor M,Chwist A,Milkiewicz P,Hartleb M

更新日期：2010-06-28 00:00:00