Transcriptional inhibitory role of the tail domains of histone (H3 x H4)2 tetramers.

abstract：:If liver alcohol dehydrogenase were rate-limiting in ethanol metabolism, inhibitors of the enzyme should inhibit the metabolism with the same type of kinetics and the same kinetic constants in vitro and in vivo. Against varied concentrations of ethanol, 4-methylpyrazole is a competitive inhibitor of purified rat liver...

journal_title：Archives of biochemistry and biophysics

authors： Plapp BV,Leidal KG,Smith RK,Murch BP

更新日期：1984-04-01 00:00:00

abstract：:Two N-terminal fusion proteins combining Escherichia coli maltose-binding protein (MBP) and the 12-transmembrane-segment pBR322 tetracycline resistance protein (Tet) have been constructed to determine the strength and location of topology control signals within the N-terminal portion of the Tet protein. The fusions co...

journal_title：Archives of biochemistry and biophysics

authors： Miller KW,Jewell JE

更新日期：1995-10-01 00:00:00

abstract：:G protein-coupled receptors can be directly modulated by changes in transmembrane voltage in a variety of cell types. Here we show that, while changes in the membrane voltage itself do not induce detectable modifications in the cytosolic Ca(2+) concentration, platelet stimulation with thrombin or the PAR-1 and PAR-4 a...

journal_title：Archives of biochemistry and biophysics

authors： Albarrán L,Dionisio N,López E,Salido GM,Rosado JA

更新日期：2013-10-15 00:00:00

abstract：:A recent note from our laboratory reported that L-band (1.2 GHz) electron paramagnetic resonance spectroscopy can be utilized in detecting the formation of Cr(V) intermediates from chromate-treated whole mice. Since Cr(V) is thought to be one of the key species in the mechanism of chromate's toxicity, we carried out a...

journal_title：Archives of biochemistry and biophysics

authors： Liu KJ,Shi X,Jiang JJ,Goda F,Dalal N,Swartz HM

更新日期：1995-10-20 00:00:00

abstract：:This paper presents previously unobserved signals in the 1H NMR spectra of oxidized and reduced [2Fe-2S]-ferredoxin from Anabaena 7120 detected at 400, 500, and 600 MHz. The signals shifted to low field exhibited longitudinal relaxation (T1) values in the range of 100-400 microseconds and line widths in the range of 1...

journal_title：Archives of biochemistry and biophysics

authors： Skjeldal L,Westler WM,Markley JL

更新日期：1990-05-01 00:00:00

abstract：:It was found that the rate of polymerization of G-actin increased with the decrease of ATP concentration. When excess ATP was replaced by chloride through anion-exchange treatment, the extent of actin polymerization did not change provided that the ionic strength was raised immediately after the treatment. In the mean...

journal_title：Archives of biochemistry and biophysics

authors： Fung BM,Eyob E

更新日期：1983-02-01 00:00:00

abstract：:To study the relationship between neutral aminopeptidase activity and hemoglobin accumulation in malaria parasites, we treated mice infected with Plasmodium berghei NYU-2 with chloroquine intraperitoneally in doses ranging from 0.3 to 3 micromol per 25 g mouse. Preparations of infected erythrocytes (normalized to repr...

journal_title：Archives of biochemistry and biophysics

authors： Fitch CD,Cai GZ,Chen YF,Ryerse JS

更新日期：2003-02-15 00:00:00

abstract：:A large number of mutations affecting the F(0) sector of Escherichia coli F(1)F(0) ATP synthase have been constructed and characterized. A subset of the missense mutations resulted in fully assembled enzyme complexes blocked in proton translocation and displaying marked decreases in ATP hydrolysis activity. The cataly...

journal_title：Archives of biochemistry and biophysics

authors： Gardner JL,Cain BD

更新日期：2000-08-01 00:00:00

abstract：:Epoxidation and hydroxylation of arachidonic acid (AA) are both catalyzed by cytochromes P450s (CYPs). The oxidized metabolites are known to be involved in the regulation of vascular tone and renal function. By using a panel of 15 human recombinant CYPs, this study demonstrates that other polyunsaturated long-chain fa...

journal_title：Archives of biochemistry and biophysics

authors： Fer M,Dréano Y,Lucas D,Corcos L,Salaün JP,Berthou F,Amet Y

更新日期：2008-03-15 00:00:00

abstract：:Low-density lipoprotein receptor-related protein (LRP)/alpha 2-macroglobulin receptor is a member of the low-density lipoprotein receptor family. It is known to bind a wide variety of unrelated ligands including alpha 2-macroglobulin-proteinase complexes, tissue plasminogen activator, apolipoprotein E-enriched very lo...

journal_title：Archives of biochemistry and biophysics

authors： Wu SM,Pizzo SV

更新日期：1996-02-01 00:00:00

abstract：:Glucocorticoid (GCs) hormones exert their actions via their cognate steroid receptors the Glucocorticoid Receptors (GR), by genomic or non-genomic mechanisms of actions. GCs regulate many cellular functions among them growth, metabolism, immune response and apoptosis. Due to their cell type specific induction of apopt...

journal_title：Archives of biochemistry and biophysics

authors： Karra AG,Tziortziou M,Kylindri P,Georgatza D,Gorgogietas VA,Makiou A,Krokida A,Tsialtas I,Kalousi FD,Papadopoulos GE,Papadopoulou KΚ,Psarra AG

更新日期：2020-11-30 00:00:00

abstract：:The presence of multiple proteases in the culture filtrate of Streptomyces moderatus was detected. After preliminary purification by ammonium sulfate precipitation and decolorization using DEAE-cellulose, the fractionation of various proteases was carried out using CM-trisacryl cation-exchange chromatography. By this ...

journal_title：Archives of biochemistry and biophysics

authors： Chandrasekaran S,Dhar SC

更新日期：1987-09-01 00:00:00

abstract：:Because of the severe limitations on growing large quantities of Drosophila affinidisjuncta in the laboratory, direct purification of alcohol dehydrogenase (ADH) from this species has proven impossible. As an alternative source of this enzyme, a cDNA encoding functional ADH was isolated from a newly constructed cDNA l...

journal_title：Archives of biochemistry and biophysics

authors： Green MM,Fang XM,Churchill P,Brennan MD

更新日期：1989-09-01 00:00:00

abstract：:Three isoenzymes of UDP-glucuronyltransferase (UDPGT) have been separated and purified from liver microsomes of untreated female rats or female rats pretreated with 3-methylcholanthrene. The UDPGT isoenzymes were purified utilizing Chromatofocusing, column isoelectric focusing, and UDP-hexanolamine Sepharose 4B affini...

journal_title：Archives of biochemistry and biophysics

authors： Falany CN,Tephly TR

更新日期：1983-11-01 00:00:00

abstract：:In an effort to identify and characterize minor forms of human liver cytochrome P450, immunoblot analyses of microsome samples were developed with antibodies to various P450s that recognized multiple human P450s. Four P450s were recognized in immunoblot analyses of human liver microsome samples developed with an antib...

journal_title：Archives of biochemistry and biophysics

authors： Wrighton SA,Stevens JC,Becker GW,VandenBranden M

更新日期：1993-10-01 00:00:00

abstract：:Bidentate cobalt(III)tetraamine adenosine triphosphate [Co(NH3)4ATP] was investigated as an inhibitor of the beef heart mitochondrial F1-ATPase. The compound was found to have a mixed noncompetitive mechanism with a Ki of 0.4 mM and an alpha of 1.4 during ATP hydrolysis. Co(NH3)4ATP also noncompetitively inhibited ATP...

journal_title：Archives of biochemistry and biophysics

authors： Steinke L,Schuster SM

更新日期：1985-05-01 00:00:00

abstract：:Recently we reported that oxidant tumor promoters can induce the oxidative modification of protein kinase C (PKC) resulting in either activation or inactivation of the kinase (R. Gopalakrishna and W. B. Anderson, Arch. Biochem. Biophys. 285, 382-387, 1991). Since retinoids previously have been shown to antagonize the ...

journal_title：Archives of biochemistry and biophysics

authors： Gundimeda U,Hara SK,Anderson WB,Gopalakrishna R

更新日期：1993-01-01 00:00:00

abstract：:Two forms of the beta-glucosidase amygdalin hydrolase (AH I and II), which catalyze the hydrolysis of (R)-amygdalin to (R)-prunasin and D-glucose, have been purified over 200-fold from mature black cherry (Prunus serotina Ehrh.) seeds. These proteins showed very similar molecular and kinetic properties but could be re...

journal_title：Archives of biochemistry and biophysics

authors： Kuroki GW,Poulton JE

更新日期：1986-06-01 00:00:00

abstract：:Germinated seeds of barley, after anaerobic treatment, produce considerable amounts of hydrogen. The anaerobic stress induces hydrogenase activity, as measured by the ability to evolve hydrogen from reduced methyl viologen. Several pieces of evidence, including bacteriological controls and induction in axenic calluses...

journal_title：Archives of biochemistry and biophysics

authors： Torres V,Ballesteros A,Fernández VM

更新日期：1986-02-15 00:00:00

abstract：:The soluble enzymatic luminescent system of the dinoflagellate Pyrocystis lunula (luciferase-luciferin) is coupled with an enzymatic NAD(P)H-dependent reaction. The enzyme is a soluble reductase (Mr 47,000) which catalyzes, in the presence of NAD(P)H, the reduction of a molecule called P630. Reduced P630 has the same ...

journal_title：Archives of biochemistry and biophysics

authors： Fresneau C,Hill M,Lescure N,Arrio B,Dupaix A,Volfin P

更新日期：1986-12-01 00:00:00

abstract：:Dystrophic chicken breast muscle mitochondria contain significantly less mitochondrial creatine kinase than normal breast muscle mitochondria. Breast muscle mitochondria from normal 16- to 40-day-old chickens contain approximately 80 units of mitochondrial creatine kinase per unit of succinate:INT (p-iodonitrotetrazol...

journal_title：Archives of biochemistry and biophysics

authors： Bennett VD,Hall N,DeLuca M,Suelter CH

更新日期：1985-07-01 00:00:00

abstract：:2,2'-Anhydro-3'-deoxy-5-ethyluridine, a new pyrimidine nucleoside analog, has been examined in terms of its binding potency to uridine phosphorylase, and its conformation in solution (NMR) was studied. 2,2'-Anhydro-3'-deoxy-5-ethyluridine has a Ki value of 3.4 microM for uridine phosphorylase from rat intestinal mucos...

journal_title：Archives of biochemistry and biophysics

authors： Veres Z,Neszmélyi A,Szabolcs A,Kiss AI,Dénes G

更新日期：1991-04-01 00:00:00

abstract：:The effects of orally administered secondary autoxidation products of linoleic acid in rat liver were investigated. Their administration led to two toxic effects on hepatic carbohydrate metabolism, as compared to the administration of saline or linoleic acid used as controls. One effect was depletion of glucose 6-phos...

journal_title：Archives of biochemistry and biophysics

authors： Ashida H,Kanazawa K,Minamoto S,Danno G,Natake M

更新日期：1987-11-15 00:00:00

abstract：:The chondrocytes of adult articular cartilage rely upon transport phenomena within their avascular extracellular matrix for many biological activities. Therefore, changes in matrix structure which influence cytokine transport parameters may be an important mechanism involved in the chondrocyte response to tissue compr...

journal_title：Archives of biochemistry and biophysics

authors： Quinn TM,Kocian P,Meister JJ

更新日期：2000-12-15 00:00:00

abstract：:The modes of action of a Vero toxin (VT2 or Shiga-like toxin II) from Escherichia coli, of ricin, and of alpha-sarcin were compared. Elongation factor 1 (EF1) and GTP-dependent Phe-tRNA binding to ribosomes in the presence of poly(U) was inhibited by these three toxins, but EF1 and guanylyl (beta, gamma-methylene)-dip...

journal_title：Archives of biochemistry and biophysics

authors： Furutani M,Kashiwagi K,Ito K,Endo Y,Igarashi K

更新日期：1992-02-14 00:00:00

abstract：:Vascular smooth muscle cell (VSMC) proliferation is a key event in the progression of atherosclerosis. Induction of both c-fos (through the transcription factor Elk-1) and c-jun, both immediate early genes, is important for the stimulation of VSMC proliferation and migration. It was earlier found that p38 mitogen-acti...

journal_title：Archives of biochemistry and biophysics

authors： Zhao M,Liu Y,Bao M,Kato Y,Han J,Eaton JW

更新日期：2002-04-15 00:00:00

abstract：:A chemical investigation has been done on blood group active glycosphingolipids of both small intestine and pancreas from two individuals, one blood group A and one blood group B. Total non-acid glycolipid fractions were prepared and the major blood group fucolipids present were purified and structurally characterized...

journal_title：Archives of biochemistry and biophysics

authors： Breimer ME

更新日期：1984-01-01 00:00:00

abstract：:In spite of the abundance of antifungal therapies, 75% of women in the world suffer from the second most common cause of vaginal infection named vulvovaginal candidiasis. This complication is characterized with overgrowth of Candida albicans. The low efficacy and side effects of current antifungal therapies have convi...

journal_title：Archives of biochemistry and biophysics

authors： Ebrahimi-Shaghaghi F,Noormohammadi Z,Atyabi SM,Razzaghi-Abyaneh M

更新日期：2021-01-22 00:00:00

abstract：:Carbohydrate Binding Modules (CBMs) targeting cellulose, xylan and mannan have been reported, however, a CBM targeting rhamnogalacturonan I (RG I) has never been identified. We had studied earlier a rhamnogalacturonan lyase (CtRGL) from Clostridium thermocellum that was associated with a family 35 CBM, Rgl-CBM35. In t...

journal_title：Archives of biochemistry and biophysics

authors： Dhillon A,Sharma K,Rajulapati V,Goyal A

更新日期：2018-09-15 00:00:00

abstract：:Osteocytes sense extracellular mechanical stimuli and transduce them into biochemical signals to regulate bone remodeling. The function is also evidenced in orthodontic tooth movement. But the underlying mechanisms haven't been clarified. Autophagy is an evolutionarily conserved cellular catabolic process which affect...

journal_title：Archives of biochemistry and biophysics

authors： Li W,Zhao J,Sun W,Wang H,Pan Y,Wang L,Zhang WB

更新日期：2020-11-15 00:00:00