Pitfalls in the economic evaluation of thrombolysis in myocardial infarction. The impact of national differences in the cost of thrombolytics and of differences in the efficacy across patient subgroups.

abstract：:Reactive thrombocytosis following cardiopulmonary bypass surgery is generally considered to be a benign condition which is transient and does not require specific therapy. We describe three patients who developed stroke in association with reactive thrombocytosis in the late recovery period following cardiopulmonary b...

journal_title：European heart journal

authors： Crowley JJ,Hannigan M,Daly K

更新日期：1994-08-01 00:00:00

abstract：:The present review summarizes the available information on the effects of the three major classes of antianginal agents (nitrates, calcium and beta-blockers) on myocardial energy metabolism. It also discusses the role of some new molecules (L-carnitine, trimetazidine and ranolazine) that have been proposed as an alter...

journal_title：European heart journal

authors： Chierchia SL,Fragasso G

更新日期：1993-11-01 00:00:00

abstract：AIMS:To assess the long-term benefit-risk ratio of drug-eluting (DES) vs. bare-metal stents (BMS) relative to stent size. METHODS AND RESULTS:All 826 consecutive BASKET (BAsel Stent Kosten-Effektivitäts Trial) patients randomized 2:1 to DES vs. BMS were followed after 3 years. Data were analysed separately for patient...

journal_title：European heart journal

authors： Pfisterer M,Brunner-La Rocca HP,Rickenbacher P,Hunziker P,Mueller C,Nietlispach F,Leibundgut G,Bader F,Kaiser C,BASKET.

更新日期：2009-01-01 00:00:00

abstract：:The effects of xamoterol 0.2 mg kg-1 i.v. and placebo on left ventricular function at rest and on exercise were compared in patients with left ventricular dysfunction due to ischaemic heart disease. Improvements were seen in systolic and diastolic function at rest, and at up to 50% of maximal exercise, without evidenc...

journal_title：European heart journal

authors： de Feyter PJ,Serruys PW

更新日期：1990-04-01 00:00:00

abstract：Aims:Naturally secreted nanovesicles known as exosomes are required for the regenerative effects of cardiosphere-derived cells (CDCs), and exosomes mimic the benefits of CDCs in rodents. Nevertheless, exosomes have not been studied in a translationally realistic large-animal model. We sought to optimize delivery and as...

journal_title：European heart journal

authors： Gallet R,Dawkins J,Valle J,Simsolo E,de Couto G,Middleton R,Tseliou E,Luthringer D,Kreke M,Smith RR,Marbán L,Ghaleh B,Marbán E

更新日期：2017-01-14 00:00:00

abstract：:The L-arginine pathway within endothelial cells in the blood vessel wall is the source of production of the endogenous nitrovasodilator, nitric oxide (NO). NO is released under basal conditions and in response to various stimuli such as shear stress and in response to platelet-derived products, coagulation factors and...

journal_title：European heart journal

authors： Lüscher TF

更新日期：1991-11-01 00:00:00

abstract：:Manifestations of congestive heart failure are frequently observed in patients with coronary disease. However, they may be predominant in patients who have sustained prior myocardial infarction, in whom left ventricular aneurysm or papillary muscle dysfunction may induce left ventricular dysfunction. A small group of ...

journal_title：European heart journal

authors： Bertrand ME,Lablanche JM,Thieuleux FA,Tilmant PY

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVES:The primary objectives of this study were to assess the feasibility of temperature-controlled radiofrequency catheter ablation of left and right sided manifest accessory pathways in patients with Wolff-Parkinson-White syndrome and to gain more insights into biophysical aspects of temperature-controlled cathe...

journal_title：European heart journal

authors： Willems S,Chen X,Kottkamp H,Hindricks G,Haverkamp W,Rotman B,Shenasa M,Breithardt G,Borggrefe M

更新日期：1996-03-01 00:00:00

abstract：:The prevalence of coronary heart disease (CHD) was determined in a general population sample of 9141 Icelandic men aged 34-79 years, and the prevalence of four different forms of CHD was estimated separately: symptomatic infarction fulfilling WHO-MONICA criteria for definite myocardial infarction; myocardial infarctio...

journal_title：European heart journal

authors： Sigurdsson E,Thorgeirsson G,Sigvaldason H,Sigfusson N

更新日期：1993-05-01 00:00:00

abstract：:The prevalence of left ventricular (LV) thrombosis and incidence of arterial embolism after acute anterior myocardial infarction (AAMI) treated with streptokinase 1.5 x 10(6) IU intravenously was studied in 136 patients enrolled consecutively in five cardiological centres. Adjunctive antithrombotic therapy was adminis...

journal_title：European heart journal

authors： Kontny F,Dale J,Hegrenaes L,Lem P,Søberg T,Morstøl T

更新日期：1993-11-01 00:00:00

abstract：AIMS:To determine the potential adjunct of high-sensitivity (hs) C-reactive protein for risk stratification in patients with stable congestive heart failure (CHF). METHODS AND RESULTS:We studied 546 consecutive patients clinically stable with an ejection fraction <45% who were referred to our centre for evaluation of ...

journal_title：European heart journal

authors： Lamblin N,Mouquet F,Hennache B,Dagorn J,Susen S,Bauters C,de Groote P

更新日期：2005-11-01 00:00:00

abstract：:Contraceptive counselling should begin early in females with heart disease, preferably directly after the start of menstruation. In coming to a decision about the method of contraception, the following issues should be considered: (i) the risk of pregnancy for the mother and the consequences of an unplanned pregnancy;...

journal_title：European heart journal

authors： Roos-Hesselink JW,Cornette J,Sliwa K,Pieper PG,Veldtman GR,Johnson MR

更新日期：2015-07-14 00:00:00

abstract：:To assess possible clinical and angiographic factors associated with acute coronary events following PTCA, we performed quantitative angiography in 168 consecutive patients who had undergone successful angioplasty in a native vessel (94 for stable angina, 74 for unstable angina), and who were restudied (24 +/- 15 week...

journal_title：European heart journal

authors： Chen L,Leatham E,Chester M,Huang J,Kaski JC

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Recent experimental and clinical data indicate that abnormal central and peripheral immune reactions contribute to the progression of chronic heart failure, and that immunomodulation may be an important therapeutic approach in this syndrome. Aims We sought to study the effects of growth hormone (GH) administ...

journal_title：European heart journal

authors： Adamopoulos S,Parissis JT,Paraskevaidis I,Karatzas D,Livanis E,Georgiadis M,Karavolias G,Mitropoulos D,Degiannis D,Kremastinos DT

更新日期：2003-12-01 00:00:00

abstract：:After years of stagnant finances for research, moves are under way to increase research funds in Europe. ...

journal_title：European heart journal

authors： Smith U,Sipido K,Dive C,Nicod L

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:In the acute phase of myocardial infarction (acute MI) marked endothelial damage occurs within the first 24h following thrombolysis with streptokinase. We investigated whether this is associated with a change in levels of vascular endothelial growth factor (VEGF, possibly marking angiogenesis) in the first 2...

journal_title：European heart journal

authors： Chung NA,Lydakis C,Belgore F,Blann AD,Lip GY

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Mortality from cardiac surgery is an essential indicator of quality and forms the basis of treatment strategy decisions in eligible patients. No contemporary complete data on unselected adult cardiac surgery patients are available in Germany. METHODS AND RESULTS:A registry was started in June 1997 of all pa...

journal_title：European heart journal

authors： Vogt A,Grube E,Glunz HG,Hauptmann KE,Sechtem U,Mäurer W,Tebbe U,Heinrich KW,Engel HJ,Kettner W,Krawietz W,Neuhaus KL

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Recent identification of mutations in the beta-myosin heavy chain gene (MYH7), a major responsible gene for HCM, has provided the opportunity to characterize genotype-phenotype correlation in HCM families. In this study we analysed the phenotypic expression of two beta-myosin heavy chain (beta MHC) mutations...

journal_title：European heart journal

authors： Marian AJ,Mares A Jr,Kelly DP,Yu QT,Abchee AB,Hill R,Roberts R

更新日期：1995-03-01 00:00:00

abstract：Aims:The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transforme...

journal_title：European heart journal

authors： Pries AR,Naoum A,Habazettl H,Dunkel M,Preissner R,Coats CJ,Tornada A,Orso F,Van de Werf F,Wood DA,CardioScape steering committee.,Van de Werf F,Wood DA,O'Kelly S,Craven J,Coats A,Sipido K,De Backer D,Wallentin L,Has

更新日期：2018-07-01 00:00:00

abstract：AIMS:Exposure of tissue factor (TF) is a critical proximal step in the pathogenesis of acute coronary syndromes. Sunol-cH36, a chimaeric monoclonal antibody to TF, blocks binding of factor X to the TF:VIIa complex. This report describes the first completed trial of Sunol-cH36 in humans. METHODS AND RESULTS:We assessed...

journal_title：European heart journal

authors： Morrow DA,Murphy SA,McCabe CH,Mackman N,Wong HC,Antman EM

更新日期：2005-04-01 00:00:00

abstract：AIMS:The very long-term outcome of patients who survive the first few years after receiving cardiac resynchronization therapy (CRT) has not been well described thus far. We aimed to provide long-term outcomes, especially with regard to the occurrence of sudden cardiac death (SCD), in CRT patients without (CRT-P) and wi...

journal_title：European heart journal

authors： Barra S,Duehmke R,Providência R,Narayanan K,Reitan C,Roubicek T,Polasek R,Chow A,Defaye P,Fauchier L,Piot O,Deharo JC,Sadoul N,Klug D,Garcia R,Dockrill S,Virdee M,Pettit S,Agarwal S,Borgquist R,Marijon E,Boveda

更新日期：2019-07-01 00:00:00

abstract：:Organic nitrates exert their effect by direct inhibition of vascular tone, resulting in decreased myocardial oxygen demand and improved oxygen supply. Less well known is the effect of nitrates on blood rheology. To evaluate the haemodiluting effect of intravenous nitroglycerin we studied 70 consecutive patients admitt...

journal_title：European heart journal

authors： Arend SM,Bax JJ,Hermans J,van der Wall EE,Sedney MI

更新日期：1994-01-01 00:00:00

abstract：AIMS:Whereas endogenous carbon monoxide (CO) is cytoprotective at physiologic levels, excess CO concentrations are associated with cardiometabolic risk and may represent an important marker of progression from subclinical to clinical cardiovascular disease (CVD). METHODS AND RESULTS:In 1926 participants of the Framing...

journal_title：European heart journal

authors： Cheng S,Enserro D,Xanthakis V,Sullivan LM,Murabito JM,Benjamin EJ,Polak JF,O'Donnell CJ,Wolf PA,O'Connor GT,Keaney JF,Vasan RS

更新日期：2014-11-07 00:00:00

abstract：AIMS:The totally subcutaneous implantable-defibrillator (S-ICD) is a new alternative to the conventional transvenous ICD system to minimize intravascular lead complications. There are limited data describing the long-term performance of the S-ICD. This paper presents the first large international patient population col...

journal_title：European heart journal

authors： Lambiase PD,Barr C,Theuns DA,Knops R,Neuzil P,Johansen JB,Hood M,Pedersen S,Kääb S,Murgatroyd F,Reeve HL,Carter N,Boersma L,EFFORTLESS Investigators.

更新日期：2014-07-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate the long-term results of allograft and prosthetic valve replacement in the treatment of infective aortic valve endocarditis with periannular abscess. METHODS:Between March 1988 and March 1996, 65 patients underwent surgery for active aortic valve endocarditis and paravalvular ...

journal_title：European heart journal

authors： Knosalla C,Weng Y,Yankah AC,Siniawski H,Hofmeister J,Hammerschmidt R,Loebe M,Hetzer R

更新日期：2000-03-01 00:00:00

abstract：UNLABELLED:Peripheral vessels provide a useful in vivo haemodynamic model allowing evaluation of local intravascular fluid dynamics. Velocity measurements using a 0.018 inch Doppler-tipped angioplasty guidewire, quantitative angiography and laboratory data were gathered from 45 patients with a total of 48 percutaneous ...

journal_title：European heart journal

authors： Wellnhofer E,Biamino G,Sauer HU,Trebeljahr A,Stalke J,Ragg C,Oswald H,Gotze S,Fleck E,Felix R

更新日期：1995-10-01 00:00:00

abstract：:Among 369 patients with native valve infective endocarditis observed during a 14-year period, 17 were related to S: pneumoniae. Fourteen of them were observed in the last 7 years. At the time of admission 13 exhibited purulent meningitis, 6 of them being comatose. An apparent portal of entry was present in 13 patients...

journal_title：European heart journal

authors： Wolff M,Regnier B,Witchitz S,Gibert C,Amoudry C,Vachon F

更新日期：1984-10-01 00:00:00

abstract：UNLABELLED:Left atrial spontaneous echo contrast, detected by transoesophageal echocardiography in patients with non-valvular atrial fibrillation reflects slow blood flow and is associated with an increased risk of cardio-embolism. The purpose of this study was to find echo/Doppler predictors of left atrial spontaneous...

journal_title：European heart journal

authors： Pop GA,Meeder HJ,Roelandt JR,van Oudenaarden W,Bulens C,Verweij W,Gijsbers C,van Domburg R,Koudstaal PJ

更新日期：1994-11-01 00:00:00

abstract：AIMS:Midwall myocardial fibrosis on cardiovascular magnetic resonance (CMR) is a marker of early ventricular decompensation and adverse outcomes in aortic stenosis (AS). We aimed to develop and validate a novel clinical score using variables associated with midwall fibrosis. METHODS AND RESULTS:One hundred forty-seven...

journal_title：European heart journal

authors： Chin CW,Messika-Zeitoun D,Shah AS,Lefevre G,Bailleul S,Yeung EN,Koo M,Mirsadraee S,Mathieu T,Semple SI,Mills NL,Vahanian A,Newby DE,Dweck MR

更新日期：2016-02-21 00:00:00

abstract：:In this study, betathromboglobulin (BTG) and fibrinopeptide A (FPA) in peripheral venous blood were measured in 20 patients with stable angina pectoris before and immediately after exercise-induced myocardial ischaemia; in 5 of the 20 patients stable angina was associated with typical peripheral artery disease. A tota...

journal_title：European heart journal

authors： Gallino A,Häberli A,Straub PW,Steinbrunn W,Turina M,Rothlin ME

更新日期：1987-07-01 00:00:00