The use of nested RT-PCR of prostate-specific membrane antigen in blood cells: implications for the detection of haematogenous neoplastic cells in patients with prostate adenocarcinoma.

Abstract:

:The aim of this study was to determine the presence of haematogenous neoplastic cells in patients with prostate cancer. Circulating prostate cells can be detected in cancer patients by using a nested-reverse transcriptase-polymerase chain reaction assay (RT-PCR), for prostate-specific membrane (PSM) antigen mRNA. This sensitive nested RT-PCR assay may play a crucial role in the administration of adjuvant therapy of patients with prostate adenocarcinoma.

journal_name

Mol Cell Probes

authors

Lucotte G,Mercier G,Burckel A

doi

10.1006/mcpr.1998.0201

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

421-5

issue

6

eissn

0890-8508

issn

1096-1194

pii

S0890-8508(98)90201-8

journal_volume

12

pub_type

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