Benzonatate for opioid-resistant cough in advanced cancer.

Abstract:

:Chronic cough is a distressing symptom experienced by approximately 37% of patients with advanced cancer. Palliation of chronic nonproductive cough should always first address the underlying cause but in some patients chronic, nonproductive cough persists and antitussive agents are required. Opioids are the gold standard cough suppressants, of which codeine is the most widely used; patients with an opioid-resistant cough often prove to be a therapeutic challenge. We report three patients with an opioid-resistant cough who achieved symptomatic relief with the peripherally acting nonopioid drug benzonatate.

journal_name

Palliat Med

journal_title

Palliative medicine

authors

Doona M,Walsh D

doi

10.1191/026921698672930910

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

55-8

issue

1

eissn

0269-2163

issn

1477-030X

journal_volume

12

pub_type

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