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Comparative in vitro activities of four new fluoroquinolones against Streptococcus pneumoniae determined by Etest.

Abstract：

:Clinafloxacin, levofloxacin, sparfloxacin and trovafloxacin were tested by Etest against 188 Streptococcus pneumoniae isolates. Clinafloxacin and trovafloxacin were 2-4-fold more potent than sparfloxacin and 8-fold more than levofloxacin. Two isolates, both serotype 6, with high-level quinolone resistance (> or = 8 micrograms/ml) were detected. The Etest is a practical means for determining S. pneumoniae susceptibilities to new fluoroquinolones.

journal_name

Int J Antimicrob Agents

journal_title

International journal of antimicrobial agents

authors

Waites K,Brookings E,Nix S,Robinson A,Gray B,Swiatlo E

doi

10.1016/s0924-8579(97)00053-8

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

215-8

issue

4

eissn

0924-8579

issn

1872-7913

pii

S0924857997000538

journal_volume

9

pub_type

杂志文章

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