The pathologic and clinical spectrum of anaplastic large cell lymphoma and correlation with ALK gene dysregulation.

abstract：:The occurrence of malignant lymphoma is an increasingly important cause of morbidity and mortality in AIDS patients. The incidence of AIDS-related lymphoma in some developing countries such as Brazil is increasing as the survival of HIV infection has improved. Although there is a clear association between several type...

journal_title：American journal of clinical pathology

authors： Bacchi CE,Bacchi MM,Rabenhorst SH,Soares FA,Fonseca LE Jr,Barbosa HS,Weiss LM,Gown AM

更新日期：1996-02-01 00:00:00

abstract：Objectives:To evaluate the prognostic values of microRNAs (miRNAs) in glioblastoma, and to see if there is an association between miRNAs and MGMT promoter methylation status. Methods:We collected paraffin blocks from resection specimens from 114 glioblastoma patients who had received temozolomide treatment and radioth...

journal_title：American journal of clinical pathology

authors： Chen YY,Ho HL,Lin SC,Ho TD,Hsu CY

更新日期：2018-03-29 00:00:00

abstract：:In today's environment, many laboratories and pathology practices are challenged to maintain or increase their quality while simultaneously lowering their overall costs. The cost of improving specimen processes is related to quality, and we demonstrate that actual costs can be reduced by designing "quality at the sour...

journal_title：American journal of clinical pathology

authors： Carlson RO,Amirahmadi F,Hernandez JS

更新日期：2012-09-01 00:00:00

abstract：:Apocrine carcinoma (AC) is an uncommon, poorly characterized type of breast tumor. In this review, 55 patients with intraductal (ID) AC and 17 patients with infiltrating (IF) AC were analyzed retrospectively to define the histologic features and clinical course of this neoplasm. Recurrences in the breast occurred in 3...

journal_title：American journal of clinical pathology

authors： Abati AD,Kimmel M,Rosen PP

更新日期：1990-10-01 00:00:00

abstract：:Two cases of giant-cell arteritis of uterus were found incidentally in association with uterine prolapse. One similar case has been reported in the literature. Microscopic examination disclosed fragmentation of the elastic laminae of the myometrial arteries with a giant-cell and mononuclear infiltrate. The relationshi...

journal_title：American journal of clinical pathology

authors： Pirozynski WJ

更新日期：1976-03-01 00:00:00

abstract：:B5 fixation achieves superior morphologic detail. However, environmental concerns have led to labor-intensive and costly requirements for disposal of mercury-containing fixatives. We performed a blinded prospective study to find a safe, mercury-free alternative to B5. Morphology was evaluated with 6 fixatives, includi...

journal_title：American journal of clinical pathology

authors： Bonds LA,Barnes P,Foucar K,Sever CE

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:To examine carbonic anhydrase IX (CAIX), a marker of renal cell carcinoma that recently has been described in malignant effusions. METHODS:Pleural and peritoneal fluids with the following diagnoses-reactive (n = 23), carcinoma (n = 17), and "suspicious for mesothelioma" (n = 4)-were immunostained for CAIX, ...

journal_title：American journal of clinical pathology

authors： Ananthanarayanan V,Tretiakova M,Husain AN,Krausz T,Antic T

更新日期：2014-07-01 00:00:00

abstract：:Because of the demonstrated efficacy of Leu-M1 as a discriminant between malignant epithelioid mesothelioma (MEM) and adenocarcinomas involving the serosal surfaces (ACSs), the authors assessed the reactivities of related "myelomonocytic" antigens in this context. Paraffin sections from 41 MEMs and 43 ACSs (pulmonary,...

journal_title：American journal of clinical pathology

authors： Wick MR,Mills SE,Swanson PE

更新日期：1990-07-01 00:00:00

abstract：:DNA sequencing was used to confirm Chlamydia trachomatis and Neisseria gonorrhoeae nucleic acids in endocervical swab samples. DNA in residues of the samples with positive results by 2 commercial kits was subjected to nested polymerase chain reaction (PCR) amplification. The nested PCR amplicons were used as templates...

journal_title：American journal of clinical pathology

authors： Lee SH,Vigliotti VS,Pappu S

更新日期：2008-06-01 00:00:00

abstract：:Pleomorphic adenoma (or benign mixed tumor) of the breast is a rare benign neoplasm that might be misinterpreted both clinically and pathologically as a malignant tumor. The authors present an additional case of this unusual lesion studied by immunohistochemistry, electron microscopy, and flow cytometry. A 77-year-old...

journal_title：American journal of clinical pathology

authors： Ballance WA,Ro JY,el-Naggar AK,Grignon DJ,Ayala AG,Romsdahl MG

更新日期：1990-06-01 00:00:00

abstract：:Mucocele-like lesion (MLL) is a rare mucinous lesion of the breast with highly variable upgrade rates to atypia or malignancy on excision. This spectrum of data has led to differing opinions on the need for surgical excision. We evaluated 50 core biopsy specimens diagnosed as having MLLs and correlated the findings wi...

journal_title：American journal of clinical pathology

authors： Sutton B,Davion S,Feldman M,Siziopikou K,Mendelson E,Sullivan M

更新日期：2012-12-01 00:00:00

abstract：:We analyzed the value in cervical cytology of a recently developed technique by which it is possible to remove thick tissue specimens, called microbiopsies, from cervical smears and to process them for histologic examination. In 12 (48%) of 25 cervical smears in which microbiopsies were found, the histologic sections ...

journal_title：American journal of clinical pathology

authors： Mravunac M,Verbeek DH,Sanders-Eras M,Besseling R,Wijnen-Dubbers C,Smedts F

更新日期：1997-08-01 00:00:00

abstract：:The immunochemical characterization of the light chains of the mesangial immunoglobulin A (IgA) deposits were studied in 45 patients with IgA nephropathy. Kappa and lambda light chains were detected with direct immunofluorescence (IF) method, using monospecific rabbit anti-human anti-kappa and anti-lambda anti-sera. T...

journal_title：American journal of clinical pathology

authors： Lai KN,Chan KW,Mac-Moune F,Ho CP,Yan KW,Lam CW,Vallance-Owen J

更新日期：1986-05-01 00:00:00

abstract：:We examined benign and malignant mesothelial tissue samples for the presence of X-linked inhibitor of apoptosis protein (XIAP), a potent constituent of the inhibitor of apoptosis family of caspase inhibitors. We subjected 55 sections (31 malignant mesotheliomas, 2 well-differentiated peritoneal mesotheliomas, 13 pleur...

journal_title：American journal of clinical pathology

authors： Wu M,Sun Y,Li G,Desman G,Wang B,Gil J,Burstein DE

更新日期：2007-11-01 00:00:00

abstract：:Recently, strains of Streptococcus pneumoniae with greatly increased resistance to penicillin (minimal inhibitory concentrations or MICs, 1--8 microgram/ml) were recovered in cultures of blood from patients in South Africa and from one in Minnesota who had serious pneumococcal infections. The authors undertook a study...

journal_title：American journal of clinical pathology

authors： Maki DG,Helstad AG,Kimball JL

更新日期：1980-02-01 00:00:00

abstract：:A 67-year-old man presented with a malignant tumor involving abdominal lymph nodes, spleen, liver, and lungs, with associated protracted fever and night sweats. The tumor consisted of large pleomorphic cells, often surrounding microabscesses. Intracytoplasmic S100 protein, surface T6, Leu-3a (T4), and HLA-DR antigens ...

journal_title：American journal of clinical pathology

authors： Chan WC,Zaatari G

更新日期：1986-06-01 00:00:00

abstract：:We describe 35 peripheral lymph nodes classified as mantle cell/marginal zone B-cell hyperplasia with clear cells using morphologic and immunologic findings. For the purpose of this study, we obtained clinical follow-up information and performed immunoglobulin gene rearrangement studies on paraffin sections by polymer...

journal_title：American journal of clinical pathology

authors： Hunt JP,Chan JA,Samoszuk M,Brynes RK,Hernandez AM,Bass R,Weisenburger DD,Müller-Hermelink K,Nathwani BN

更新日期：2001-10-01 00:00:00

abstract：:The levels of thymus-derived lymphocytes (T-cells) in samples of peripheral blood from 47 patients with carcinoma of the breast, 36 patients with benign mammary lesions, and 33 matched normal controls were determined. Results were analyzed with three statistical tests. It was found that the mean percentages of T-lymph...

journal_title：American journal of clinical pathology

authors： Keller SE,Ioachim HL,Pearse T,Siletti DM

更新日期：1976-04-01 00:00:00

abstract：:The prehospital environment has not been studied for point-of-care testing. Therefore, the authors' helicopter program evaluated the performance of the i-STAT Portable Clinical Analyzer, a rapid point-of-care, hand-held instrument. The primary aim of the study was to determine if the i-STAT Portable Clinical Analyzer ...

journal_title：American journal of clinical pathology

authors： Herr DM,Newton NC,Santrach PJ,Hankins DG,Burritt MF

更新日期：1995-10-01 00:00:00

abstract：:A parallel study of blood cultured conventionally and following processing in an Antimicrobial Removal Device (ARD) was conducted with patients suspected of being clinically bacteremic. Cultures yielded 205 isolates from 87 clinically bacteremic patients, of whom 28 were receiving antibiotics at the time their culture...

journal_title：American journal of clinical pathology

authors： Wright AJ,Thompson RL,McLimans CA,Wilson WR,Washington JA 2nd

更新日期：1982-08-01 00:00:00

abstract：:Transketolases link the Embden-Meyerhof pathway to the pentose phosphate pathway. An influence of p-Akt on this metabolism was described. This study was performed to compare the expression of transketolase-like 1 (TKTL1) and p-Akt in glioblastoma multiforme (GBM) and other astrocytic gliomas (AGs, grades II and III). ...

journal_title：American journal of clinical pathology

authors： Völker HU,Hagemann C,Coy J,Wittig R,Sommer S,Stojic J,Haubitz I,Vince GH,Kämmerer U,Monoranu CM

更新日期：2008-07-01 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors characterized by mutations of KIT or PDGFRA. The objectives of this study were to evaluate BRAF mutations in GISTs and then to correlate BRAF mutational status in the tumor with clinical parameters, with B-raf expression, and with activation of some cellul...

journal_title：American journal of clinical pathology

authors： Hostein I,Faur N,Primois C,Boury F,Denard J,Emile JF,Bringuier PP,Scoazec JY,Coindre JM

更新日期：2010-01-01 00:00:00

abstract：:This study assessed the value of argyrophilic nucleolar organizer region (AgNOR) staining as a potential technique for the estimation of cell kinetics in conventional histology sections, in benign and malignant breast lesions. Using a silver staining technique and immunohistochemistry, the authors correlated the numbe...

journal_title：American journal of clinical pathology

authors： Dervan PA,Gilmartin LG,Loftus BM,Carney DN

更新日期：1989-10-01 00:00:00

abstract：:Encephalitozoon (Septata) intestinalis affects AIDS patients with CD4 counts <100/microL, causing intestinal and disseminated disease. It must be distinguished from the more common intestinal microsporidian, Enterocytozoon bieneusi, and from other microsporidia of extraintestinal tissues, such as Encephalitozoon helle...

journal_title：American journal of clinical pathology

authors： Chu P,West AB

更新日期：1996-11-01 00:00:00

abstract：:Session 1 of the 2007 Workshop of the Society for Hematopathology/European Association for Haematopathology focused on chronic myelogenous leukemia, BCR-ABL1+ (CML). CML is a myeloproliferative neoplasm arising at the level of a pluripotent stem cell and consistently associated with the BCR-ABL1 fusion gene. CML most ...

journal_title：American journal of clinical pathology

authors： Vardiman JW

更新日期：2009-08-01 00:00:00

abstract：Objectives:To analyze interobserver reproducibility and compare practice patterns between academic and community settings of Lower Anogenital Squamous Terminology (LAST). Methods:In total, 132 anal biopsy slides were revised as well as p16 immunostains. Results:LAST was used in 49% of cases (academic center, 68%; sat...

journal_title：American journal of clinical pathology

authors： Roma AA,Liu X,Patil DT,Xie H,Allende D

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:α1-Antitrypsin (AAT) deficiency is associated with an increased risk for lung and liver disease. Identification of AAT deficiency as the underlying cause of these diseases is important in correct patient management. METHODS:AAT deficiency is commonly diagnosed by demonstrating low concentrations of AAT foll...

journal_title：American journal of clinical pathology

authors： Suh-Lailam BB,Procter M,Krautscheid P,Haas J,Kumar S,Mao R,Grenache DG

更新日期：2014-05-01 00:00:00

abstract：:A nodule of the liver was incidentally noted during left colectomy for a large villous adenoma in a 74-year-old man. Microscopic examination disclosed a granuloma of the liver containing numerous Enterobius vermicularis ova and a cross-section of the nematode. This is the fourth reported case of hepatic oxyuriasis and...

journal_title：American journal of clinical pathology

authors： Mondou EN,Gnepp DR

更新日期：1989-01-01 00:00:00

abstract：:Several technics are currently being used to detect hepatitis type A antigen or its antibody. These include immunoelectronmicroscopy, immune adherence, and complement fixation. This paper describes another promising technic, a microtiter solid-phase immunoradiometric assay, in which hepatitis A antigen and antibody ar...

journal_title：American journal of clinical pathology

authors： Hollinger FB,Bradley DW,Dreesman GR,Melnick JL

更新日期：1976-05-01 00:00:00

abstract：:Estrogen receptor (ER) status of breast carcinomas determines prognosis and treatment. Biochemical ER assays are expensive and time-consuming and require fresh tumor. Immunohistochemical ER was assessed in 68 breast carcinomas, by an automated method using routinely processed formalin-fixed paraffin-embedded tissues, ...

journal_title：American journal of clinical pathology

authors： Cohen C,Unger ER,Sgoutas D,Bradley N,Chenggis M

更新日期：1989-11-01 00:00:00