Abstract:
:Endothelial cell proliferation and differentiation into blood capillaries (i.e., angiogenesis) are essential for growth and development, wound healing, osetogenesis, etc. But abnormal angiogenesis during tumor progression could lead to serious consequences. Angiogenesis is a complex biochemical process, and is often difficult to study the molecular mechanism in vivo due to interference by multitude of factors. Here, I present a non-transformed capillary endothelial cell line as a model which has been extensively characterized morphologically and biochemically to study the fundamentals of the angiogenic process. Studies completed in our laboratory also evidenced that expression of Glc3Man9GlcNAc2-PP-Dol is intricately connected with the balance between the cellular proliferation and apoptosis during angiogenesis.
journal_name
P R Health Sci Jjournal_title
Puerto Rico health sciences journalauthors
Banerjee DKsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
327-33issue
4eissn
0738-0658issn
2373-6011journal_volume
17pub_type
杂志文章abstract:OBJECTIVE:to estimate the prevalence of pit and fissure sealants on first permanent molars in twelve year olds living in Puerto Rico and to further evaluate dental sealant prevalence by (1) urban/rural and public/private school status as well as (2) gender; DESIGN:population-based, cross-sectional study. SETTING:publ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::There has been a constant increase in the incidence of dengue in the Americas over the past 15 years. This has been caused by increased frequency of epidemic activity in most countries, as a result of increased numbers of virus serotypes circulating in the region. The change in disease ecology has resulted in the emer...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:1987-08-01 00:00:00
abstract::This paper examines the characteristics of youngsters in drug treatment who volunteer for AIDS testing in comparison to those who do not. HIV Antibodies testing was offered on a voluntary basis to a sample of 250 Puerto Rican youngsters enrolled in three ambulatory drug treatment centers in 1991. Sixty-six percent of ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Although regeneration in the peripheral nervous system (PNS) after injury is robust, regeneration in the central nervous system (CNS) is abortive. The results from differences in the balance of regeneration inhibiting and promoting factors, which in the CNS is skewed toward inhibition while in the PNS it is skewed tow...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
abstract::Advances in the understanding of chondrocytes and the synovial membrane as targets of and participants in the inflammatory process in articular joints have provided insights into the role of inflammation in cartilage and subchondral bone injury in rheumatic diseases. Reports that describe the inflammatory cellular inf...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2017-09-01 00:00:00
abstract::Exposure to lead in children living on a former landfill in Vega Baja-Puerto Rico, a United States Environmental Protection Agency (USEPA) designated Superfund Site, is a major health concern. Direct contact with lead-contaminated soil is considered a major exposure source. However, there is a lack of information rega...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Plant materials represent promising sources of anti-cancer agents. We developed and tested a novel extract from the ubiquitous plant Convolvulus arvensis. MATERIALS AND METHODS:Convolvulus arvensis components were extracted in boiling water, and small molecules were removed by high-pressure filtration. The ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::Primary hepatic actinomycosis is an uncommon entity. We report the case of a young man with past history of an appendectomy who presented with fever, weight loss and a liver mass that was initially suspected to be neoplastic. Percutaneous liver biopsy revealed actinomyces-like organisms. The patient was treated with i...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVE:Puerto Rican children could have a higher prevalence of obesity, compared to US children or even to US Hispanic children. Obese youths are more likely to have risk factors for cardiovascular conditions, such as hypertension. Although BMI provides a simple, convenient measurement of obesity, it does not measur...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract::This is the case of an 11-year-old girl who presented with a right adnexal mass and vague abdominal symptoms since seven months prior to her hospital admission for surgery. CT-scan and sonographic images were those of a benign lesion, probably ovarian torsion or infarction. Serum tumoral markers were normal. A right s...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To determine the frequency of pediatric brain tumors treated at the University Pediatric Hospital of Puerto Rico over a 6-year period and examine the demographic data and tumor histology of patients in different age groups. METHODS:A retrospective study was undertaken at the University Pediatric Hospital. We...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the utility of the substituted judgement standard in terminally ill patients by determining agreement between patients, family proxies and physicians. BACKGROUND:Several studies have addressed the utility of substituted judgement, showing conflicting data whether surrogates are accurate predictin...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To determine the IgE reactivity against recombinant protein Blo t 1 from the dust mite Blomia tropicalis (Bt) using serum from patients with positive skin test to this mite and to investigate the cross-reactivity between Bt and Dermatophagoides pteronyssinus. BACKGROUND:Dust mites have an important role as i...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::The therapy of chronic myeloid leukemia (CML), characterized by the presence of the Philadelphia chromosome in the clonal hematopoietic stem cells, has changed dramatically in the last year with the development of a specific inhibitor of the BCR-ABL tyrosine kinase. This medication, STI571 or imatinib, was recently ap...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract::A questionnaire entitled "Attitude toward tobacco usage among health professionals in Puerto Rico" was administered to medical students completing their first and fourth years respectively at the University of Puerto Rico Medical School. Percent of each group currently smoking was found to be 18.5 and 10.8 with an ave...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1987-08-01 00:00:00
abstract::Hypopharyngeal carcinoma as a subsite of head and neck cancer, carries with it the lowest 5-year relative survival rate. Treatment of hypopharyngeal cancer relies on single therapy or multimodality treatment: surgery, radiation and/or chemotherapy. When surgical intervention is chosen, the type of operation depends on...
journal_title:Puerto Rico health sciences journal
pub_type:
doi:
更新日期:2020-03-01 00:00:00
abstract::Breastfeeding mothers need orientation and help in order to succeed with breastfeeding. Lack of support from health professionals and societal barriers result in a median duration of breastfeeding in Puerto Rico of only 3 weeks. A telephone warm line at our breastfeeding clinic tries to provide some much-needed suppor...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:Burnout exerts a significant negative influence on job performance, especially in such difficult jobs as those to be found in the health care industry. This research aimed to evaluate the association between 3 dimensions of burnout and demographic factors among the medical staff working in all of the hospital...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2015-12-01 00:00:00
abstract::Diagnosing cancer using microarray analysis to study differential gene expression has been a recent focus of intense research Although several very sophisticated analysis tools have been developed with this aim in mind, it still remains a challenge to keep these methods free of parametric adjustments as well as mainta...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION:Neoplasms of the heart are extremely rare and difficult to diagnose. In this study, we intend to describe the experience at the Cardiovascular Center of Puerto Rico and the Caribbean (CCPRC) dealing with benign cardiac neoplasms. METHODS:A retrospective review of the archival material at our institution w...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2008-12-01 00:00:00
abstract::Post-mortem medical examiner samples may be useful for sentinel surveillance of disorders usually detected by antibody determinations on specimens from ill patients or from surveys. We found anti-dengue IgM positivity in 3% (23/780) and anti-dengue IgG positivity in 77% (597/777) of sera obtained at the Puerto Rico me...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2006-03-01 00:00:00
abstract::Significant new findings in the last decade have demonstrated that the vascular endothelium is an important regulatory organ in maintaining cardiovascular homeostasis and that endothelial dysfunction is present in several cardiovascular diseases. With the production of multiple vasoactive substances the normal endothe...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVE:This study was conducted to determine the experience of tooth loss, as well as its associated variables, in a sample of adult Mexicans, aged 60 years and older. MATERIALS AND METHODS:This cross-sectional study was part of a larger project to measure diverse oral health indicators in a convenience sample: it ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To examine the relationship of the symptoms of diarrhea and fatigue by testing a model that included multiple dimensions of the cancer related-symptom experience. METHODS:A secondary data analysis was conducted on data from the self-reports of 102 cancer patients co experiencing diarrhea and fatigue during t...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that fermentable fiber prevents Salmonella typhimurium infection-associated symptoms by enhancing innate and adaptive immune system in neonatal pigs. METHODS:Two-d-old piglets (n=120) were randomized to receive either a nutritionally complete sow milk replacer formula (CON), or supplem...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2020-12-01 00:00:00
abstract::The development of new drugs for the pharmacological treatment of diseases is a costly and time-consuming process. The pharmaceutical industry has traditionally played the main role in the discovery, development, manufacturing and marketing of new drugs. However, in recent years, the role of academia in the process of...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract::Renal cell carcinoma is the most common cancer of the kidney and is among the tumors that are the most resistant to systemic therapy. Until recently, long term survival of this disease when it was not confined to the kidney was dismal, with the use of drugs such as interleukin-2 resulting in a 5-year survival rate of ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2011-06-01 00:00:00
abstract::DNA microarray is a technology that simultaneously evaluates quantitative measurements for the expression of thousands of genes. DNA microarrays have been used to assess gene expression between groups of cells of different organs or different populations. In order to understand the role and function of the genes, one ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-06-01 00:00:00
abstract::Prenatal sonographic evaluation is of utmost importance in the detection of congenital anomalies. At the Ultrasound Section of our Radiology service, we incidentally detected fetal intracranial neoplasms in two different patients using non-invasive imaging. Our presumptive diagnosis in both cases was a teratoma, the m...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::This is a case report of a patient who developed a nodule in one foot, which upon biopsy, was diagnosed as tungiasis, a cutaneous infestation caused by a human flea. The natural life cycle, clinical and pathological expressions are discussed. ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2007-12-01 00:00:00