The use of intravenous opioids to provide analgesia in critically ill, premature neonates: a research critique.

Abstract:

:The intravenous (i.v.) administration of opioids to neonates is a common method of providing analgesia in the intensive care setting. This paper reviews and critiques the studies that have investigated this intervention. The studies are grouped into four major areas: pharmacokinetic studies; i.v. opioids for anesthesia; i.v. opioids for sedation or analgesia in mechanically ventilated neonates; and cardiorespiratory effects of i.v. opioids. An attempt is made to synthesize current knowledge about the analgesic effects and side effects associated with the use of i.v. opioids in neonates. The intent is to stimulate additional research on the management of neonatal pain using opioid analgesics.

journal_name

J Pain Symptom Manage

authors

Franck LS,Miaskowski C

doi

10.1016/S0885-3924(97)00272-8

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

41-69

issue

1

eissn

0885-3924

issn

1873-6513

pii

S0885-3924(97)00272-8

journal_volume

15

pub_type

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