Abstract：
:Previous work with cultured primary cells, from our group and from other laboratories, has shown that signals from extracellular matrix, transduced by integrins, play critical roles in regulating gene expression, tissue-specific differentiation, and survival of primary osteoblasts and fibroblasts. This summary will focus on our most recent work, dealing with the role of cell-extracellular matrix interactions and focal adhesion kinase in regulating cell survival in osteoblasts and fibroblasts, and the role of beta1 integrins in tissue organization and remodeling in bone.
journal_name
Bonejournal_title
Boneauthors
Damsky CHdoi
10.1016/s8756-3282(99)00106-4subject
Has Abstractpub_date
1999-07-01 00:00:00pages
95-6issue
1eissn
8756-3282issn
1873-2763pii
S8756-3282(99)00106-4journal_volume
25pub_type
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