Abstract:
:The mixed-field dosimetry for 252Cf Applicator Tube (AT) type medical sources available from Oak Ridge National Laboratory (ORNL) has been characterized using ionization chambers, a GM counter, and Monte Carlo methods. Unlike the AAPM Task Group No. 43 (TG-43), specification of dose to muscle instead of water is recommended for clinical dosimetry of 252Cf medical sources. A dosimetry protocol similar to ICRU 45 was formulated with parameters determined specifically for 252Cf brachytherapy. Comparisons of experimental and calculative dosimetry results with Colvett et al. [Phys. Med. Biol. 17, 356-364 (1972)] and Krishnaswamy [Phys. Med. Biol. 17, 56-63 (1972)] were performed, and correction factors were determined to compare the different dosimetry formalisms. Using a Maxwellian model for the 252Cf neutron energy spectrum, kerma relative to muscle was determined for a variety of materials, and compared with relative kermas for external neutron beams of three different energies. Neutron isodose distributions and data necessary for clinical implementation of 252Cf AT sources are also presented.
journal_name
Med Physjournal_title
Medical physicsauthors
Rivard MJdoi
10.1118/1.598646subject
Has Abstractpub_date
1999-08-01 00:00:00pages
1503-14issue
8eissn
0094-2405issn
2473-4209journal_volume
26pub_type
杂志文章相关文献
MEDICAL PHYSICS文献大全abstract:PURPOSE:Metastatic melanoma lesions experienced marked regression after systemic targeted alpha therapy in a phase 1 clinical trial. This unexpected response was ascribed to tumor antivascular alpha therapy (TAVAT), in which effective tumor regression is achieved by killing endothelial cells (ECs) in tumor capillaries ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3681010
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:The authors are developing a system for calibrated breast density measurements using full field digital mammography (FFDM). Breast tissue equivalent (BTE) phantom images are used to establish baseline (BL) calibration curves at time zero. For a given FFDM unit, the full BL dataset is comprised of approximately ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4903299
更新日期:2015-02-01 00:00:00
abstract::The BrachySeed model LS-1 is one of the latest in a series of new brachytherapy 125I seeds that have recently become available commercially for interstitial implants. The dosimetric properties of the seed were investigated analytically, experimentally, and by Monte Carlo simulation. Following the AAPM Task Group 43 fo...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1445411
更新日期:2002-02-01 00:00:00
abstract::Weighting of given doses from parallel opposed fields is a widespread practice in radiation therapy of cancer in the tonsillar region. In order to determine when weighting is useful, dose distributions on the central axis were calculated for various energies (60Co, 4-, 8-, 15-, and MVp photons), weighting factors, and...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.594276
更新日期:1976-03-01 00:00:00
abstract::Recently, the clinical application of electronic portal imaging devices has enabled more frequent verification of patient setup for radiation treatment. However, the image quality has sometimes proven to be inadequate, motivating the investigation of alternative sensors with better image quality. Amorphous selenium (a...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.598219
更新日期:1998-04-01 00:00:00
abstract:PURPOSE:Current respiratory motion monitoring devices used for motion synchronization in medical imaging and radiotherapy provide either 1D respiratory signal over a specific region or 3D information based on few external or internal markers. On the other hand, newer technology may offer the potential to monitor the en...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3589131
更新日期:2011-06-01 00:00:00
abstract::The dosimetry for radiocolloid therapy of cystic craniopharyngiomas is investigated. Analytical calculations based on the Loevinger and the Berger formulas for electrons and photons, respectively, are compared with Monte Carlo simulations. The role of the material of which the colloid introduced inside the craniophary...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1599653
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:To assess the image quality, scatter, and leakage radiation of an integrated magnetic resonance linear accelerator (MR-LINAC or MRL) system. METHODS:A large American College of Radiology (ACR) magnetic resonance imaging (MRI) accreditation phantom was used to evaluate the MRI capabilities of the integrated MRL...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.12767
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:Radiotherapy is an effective treatment for many types of cancer in clinical settings. Gel dosimetry has the potential to record three-dimensional (3D) dose distribution compared to a conventional ion chamber. As the elasticity of the gel is altered after irradiation due to gel polymerization, we aim to measure ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14020
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:Cone beam computed tomography (CBCT) suffers from a large amount of scatter, resulting in severe scatter artifacts in the reconstructions. Recently, a new scatter correction approach, called improved primary modulator scatter estimation (iPMSE), was introduced. That approach utilizes a primary modulator that is...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.12094
更新日期:2017-09-01 00:00:00
abstract::The geometric accuracy and precision of an image-guided treatment system were assessed. Image guidance is performed using an x-ray volume imaging (XVI) system integrated with a linear accelerator and treatment planning system. Using an amorphous silicon detector and x-ray tube, volumetric computed tomography images ar...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2143141
更新日期:2006-01-01 00:00:00
abstract::We have reported in our previous studies on the methodology, and feasibility of 4D-PET (Gated PET) acquisition, to reduce respiratory motion artifact in PET imaging of the thorax. In this study, we expand our investigation to address the problem of respiration motion in PET/CT imaging. The respiratory motion of four l...
journal_title:Medical physics
pub_type: 临床试验,杂志文章
doi:10.1118/1.1809778
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:A joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.12459
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:High-quality radiation therapy using highly conformal dose distributions and image-guided techniques requires optimum machine delivery performance. In this work, a monitoring system for multileaf collimator (MLC) performance, integrating semiautomated MLC quality control (QC) tests and statistical process contr...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4901520
更新日期:2014-12-01 00:00:00
abstract::Our purpose in this work is to demonstrate that the efficiency of dose-rate computations in 125I brachytherapy, using multigroup discrete ordinates radiation transport simulations, can be significantly enhanced using broad energy group cross sections without a loss of accuracy. To this end, the DANTSYS multigroup disc...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1429238
更新日期:2002-02-01 00:00:00
abstract::Postoperative beta-irradiation after pterygium excision has been considered a valuable therapeutic procedure to reduce the recurrence rate. Recently, it was reported that beta-irradiation also substantially reduced the risk of surgical failure after glaucoma surgery. Pure beta-irradiation using a 90Sr/Y applicator has...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2896076
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:Two ultra-high-resolution (UHR) computed tomography (CT) scanners are clinically available. One is achieved by a CT system with a 0.25 mm × 160 row detector (Detector-UHR), whereas the other is with a 0.6 mm × 32 row detector with in-plane comb filtering in a dual source CT (Comb-UHR). We compared radiation dos...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.13949
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:In cardiac ablation therapy, accurate anatomic guidance is necessary to create effective tissue lesions for elimination of left atrial fibrillation. While fluoroscopy, ultrasound, and electroanatomic maps are important guidance tools, they lack information regarding detailed patient anatomy which can be obtaine...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4861712
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Computed tomography (CT) and, in particular, cone beam CT (CBCT) have been increasingly used as a diagnostic tool in recent years. Patient motion during acquisition is common in CBCT due to long scan times. This results in degraded image quality and may potentially increase the number of retakes. Our aim was to...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.13731
更新日期:2019-10-01 00:00:00
abstract::Absorbed doses from main charged-particle beams and charged-particle fragments have been measured with high accuracy for particle therapy, but there are few reports for doses from neutron components produced as fragments. This study describes the measurements on neutron doses produced by carbon beams; microdosimetric ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2767933
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:To study if malfunction of a receiver can be detected robustly using the simple ACR SNR measurement approach on a 32-channel head coil. METHODS:Standard ACR T1W images (11slice) were acquired with a commercial 32 channel head coil on a 3T Philips Achieva MR scanner following the ACR recommended setup. Raw data...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4736227
更新日期:2012-06-01 00:00:00
abstract::An automated data-acquisition and analysis system has been developed for dosimetry measurements on the pion therapy beam at the Clinton P. Anderson Meson Physics Facility Biomedical Channel in Los Alamos using a PDP-11/45 computer and CAMAC interface. Initialization, test, and monitor programs allow the user to set th...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.594418
更新日期:1978-03-01 00:00:00
abstract::The Gafchromic EBT was recently introduced in film dosimetry for external beam therapy (EBT). The high spatial resolution, weak energy dependence, and near-tissue equivalence of EBT films make them suitable for measurement of dose distributions in radiotherapy, especially intensity-modulated radiation therapy (IMRT). ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2362876
更新日期:2006-11-01 00:00:00
abstract::We have previously investigated a method of high-energy x-ray spectral reconstruction from transmission data by direct resolution of a matrix system. This technique uses the spectral vectorial algebra formalism. The resolution has previously been tested on a 12 MV photon beam. To extend and to test the validity of the...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.597998
更新日期:1997-05-01 00:00:00
abstract::An x-ray computed microtomography system for specimen and small animal imaging was built and tested. The system used seventeen 48-microm-wide detector arrays (a charge coupled device camera) and helical acquisition techniques. Images were acquired using 540 rays/view and 400 views/2pi. The modulation transfer function...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.598662
更新日期:1999-08-01 00:00:00
abstract::The purpose of this study is to incorporate the dosimetric effect of random patient positioning uncertainties directly into a commercial treatment planning system's IMRT plan optimization algorithm through probabilistic treatment planning (PTP) and compare coverage of this method with margin-based planning. In this wo...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3176940
更新日期:2009-09-01 00:00:00
abstract:INTRODUCTION:Ultrasound (US) guidance of the prostate has long been conducted using a transabdominal (TA) approach. More recently, a transperineal (TP) approach has been made available for image guidance. Our aim was to determine if both methods produced similar alignments within the same patients. MATERIALS AND METHO...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14522
更新日期:2020-12-01 00:00:00
abstract::The minimum margins required to compensate for random geometric uncertainties in the delivery of radiotherapy treatment were determined for a spherical Clinical Target Volume, using an analytic model for the cumulative dose. Margins were calculated such that the minimum dose in the target would be no less than 95% of ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1809991
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:Magnetic resonance imaging (MRI) is increasingly used for radiotherapy target delineation, image guidance, and treatment response monitoring. Recent studies have shown that an entire external x-ray radiotherapy treatment planning (RTP) workflow for brain tumor or prostate cancer patients based only on MRI refer...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4958677
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:There are growing expectations that imaging biomarkers for tumor therapeutic drug response assessment will speed up preclinical testing of anticancer drugs in rodent models. The only imaging biomarker presently approved by the U.S. Food and Drug Administration is tumor size measurement based on either World Hea...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3464491
更新日期:2010-09-01 00:00:00