Mortality and the increase in length of stay attributable to the acquisition of Acinetobacter in critically ill patients.

abstract：OBJECTIVE:Treatment of preterm infants with respiratory distress syndrome (RDS) with exogenous surfactant has greatly improved clinical outcome. Some infants require multiple doses, and it has not been studied whether these large amounts of exogenous surfactant disturb endogenous surfactant metabolism in humans. We stu...

journal_title：Critical care medicine

authors： Bunt JE,Carnielli VP,Janssen DJ,Wattimena JL,Hop WC,Sauer PJ,Zimmermann LJ

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Sepsis-induced multi-organ failure continues to have a high mortality. The liver is an organ central to the disease pathogenesis. The objective of this study was to identify the liver proteins that change in abundance with sepsis and subsequently identify new drug targets. DESIGN:Proteomic discovery study an...

journal_title：Critical care medicine

authors： Dear JW,Leelahavanichkul A,Aponte A,Hu X,Constant SL,Hewitt SM,Yuen PS,Star RA

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:There is substantial variation in use of life sustaining technologies in patients near the end of life but little is known about variation in physicians' initial ICU admission and intubation decision making processes. Our objective is to describe variation in hospital-based physicians' communication behavior...

journal_title：Critical care medicine

authors： Uy J,White DB,Mohan D,Arnold RM,Barnato AE

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the ability of central venous-to-arterial carbon dioxide pressure difference, central venous oxygen saturation, and the combination of these two parameters to detect extubation failure in critically ill patients. DESIGN:Multicentric, prospective, observational study. SETTING:Three ICUs. PATIEN...

journal_title：Critical care medicine

authors： Mallat J,Baghdadi FA,Mohammad U,Lemyze M,Temime J,Tronchon L,Thevenin D,Fischer MO

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the ability of two prognostic systems to predict hospital mortality in adult intensive care patients. DESIGN:Prospective cohort study. SETTING:A mixed medical and surgical intensive care unit (ICU) in the United Kingdom. PATIENTS:A total of 1,144 patients consecutively admitted to the study. I...

journal_title：Critical care medicine

authors： Beck DH,Taylor BL,Millar B,Smith GB

更新日期：1997-01-01 00:00:00

abstract：:Data at ICU admission and after 24 h in the ICU were collected on 755 patients, to derive multiple logistic regression models for predicting hospital mortality. The derived models contained relatively few and easily obtained variables. The weight associated with each variable was determined objectively. There were sev...

journal_title：Critical care medicine

authors： Lemeshow S,Teres D,Pastides H,Avrunin JS,Steingrub JS

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:Although the majority of sudden cardiac arrests occur in patients with ischemic heart disease, the effect of therapeutic hypothermia on arrhythmia susceptibility during acute global ischemia is not well understood. While both ischemia and severe hypothermia are arrhythmogenic, patients undergoing therapeutic...

journal_title：Critical care medicine

authors： Piktel JS,Rosenbaum DS,Wilson LD

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:This study was done to assess the effects of temperature on bleeding time and clotting time in normal male and female volunteers. DESIGN:Open study utilizing normal volunteers. SETTING:University research laboratory. SUBJECTS:Fifty-four healthy male and female volunteers, ranging in age from 19 to 35 yrs, ...

journal_title：Critical care medicine

authors： Valeri CR,MacGregor H,Cassidy G,Tinney R,Pompei F

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:To determine nuclear factor kappa B (NF-kappa B) activation in mononuclear and neutrophils from critically ill patients and to compare NF-kappa B activation with circulating concentrations of interleukin (IL)-6, IL-8, and soluble intercellular adhesion molecule (sICAM)-1. DESIGN:Observational study. SETTIN...

journal_title：Critical care medicine

authors： Paterson RL,Galley HF,Dhillon JK,Webster NR

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To review the incidence, diagnosis, and management of septic emboli caused by vascular catheters after surgery for congenital heart disease. DESIGN:Retrospective clinical review. All patients were computer registered. Our database includes daily follow-up and every sign of infection registered. SETTING:Pedi...

journal_title：Critical care medicine

authors： Erez E,Sharoni E,Ovadia B,Vidne BA,Dagan O

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVES:Lung CT is the reference imaging technique for acute respiratory distress syndrome, but requires transportation outside the intensive care and x-ray exposure. Lung ultrasound is a promising, inexpensive, radiation-free, tool for bedside imaging. Aim of the present study was to compare the global and regional...

journal_title：Critical care medicine

authors： Chiumello D,Umbrello M,Sferrazza Papa GF,Angileri A,Gurgitano M,Formenti P,Coppola S,Froio S,Cammaroto A,Carrafiello G

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:A lack of intensive care units beds in Israel results in critically ill patients being treated outside of the intensive care unit. The survival of such patients is largely unknown. The present study's objective was to screen entire hospitals for newly deteriorated patients and compare their survival in and ou...

journal_title：Critical care medicine

authors： Simchen E,Sprung CL,Galai N,Zitser-Gurevich Y,Bar-Lavi Y,Levi L,Zveibil F,Mandel M,Mnatzaganian G,Goldschmidt N,Ekka-Zohar A,Weiss-Salz I

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are devastating disorders of overwhelming pulmonary inflammation and hypoxemia, resulting in high morbidity and mortality. AIM:To provide the clinician with a summary of the literature on the epidemiology, diagnosi...

journal_title：Critical care medicine

authors： Randolph AG

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:This report will describe the preparations for and the provision of care of two patients with Ebola virus disease in the biocontainment unit at the University of Nebraska Medical Center. DATA SOURCES:Patient medical records. STUDY SELECTION:Not applicable. DATA EXTRACTION:Not applicable. DATA SYNTHESIS:No...

journal_title：Critical care medicine

authors： Johnson DW,Sullivan JN,Piquette CA,Hewlett AL,Bailey KL,Smith PW,Kalil AC,Lisco SJ

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To explore the feedback regulation of glucocorticoids on corticotropin secretion in patients with septic and nonseptic circulatory shock. DESIGN:Prospective study. SETTING:An intensive care unit of a general hospital. PATIENTS:Two groups of patients with septic shock (n = 11) or nonseptic shock (n = 7). A ...

journal_title：Critical care medicine

authors： Perrot D,Bonneton A,Dechaud H,Motin J,Pugeat M

更新日期：1993-03-01 00:00:00

abstract：:PEEP is the most important therapeutic intervention in the management of acute respiratory failure. Transitory PEEP disconnection to perform clinically relevant maneuvers is often necessary, but its effect upon PaO2 and physiological shunt in patients requiring high-level PEEP is not clear from the literature. Nine ad...

journal_title：Critical care medicine

authors： De Campo T,Civetta JM

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVES:To characterize the rates of accidental removal of endotracheal tubes, nasogastric tubes, central venous catheters, and arterial catheters. To assess the efficacy of corrective measures aimed at reducing the accidental removal of these devices. DESIGN:Prospective, observational, and interventional study. S...

journal_title：Critical care medicine

authors： Carrión MI,Ayuso D,Marcos M,Paz Robles M,de la Cal MA,Alía I,Esteban A

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To comparatively evaluate cerebral metabolic rate of oxygen consumption and a modification of it, cerebral consumption of oxygen, in patients with acute brain injury with acute anemia. DESIGN:Prospective, observational study. SETTING:Neuroscience intensive care unit (ICU) of a university hospital. PATIENTS...

journal_title：Critical care medicine

authors： Cruz J,Jaggi JL,Hoffstad OJ

更新日期：1993-08-01 00:00:00

abstract：:In a prospective randomized study to determine whether prevention of colonization of Gram-negative bacteria results in prevention of Gram-negative bacterial infections, 96 intensive care patients were randomly allocated into a control group and a study group. The study group received oral nonabsorbable antimicrobial a...

journal_title：Critical care medicine

authors： Kerver AJ,Rommes JH,Mevissen-Verhage EA,Hulstaert PF,Vos A,Verhoef J,Wittebol P

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:Toxic free radicals cause dysfunction of respiratory muscles, probably leading to respiratory distress. Exposure to high concentrations of oxygen generates plenty of free radicals. Lidocaine scavenges the reactive molecules. The purposes of the current study were first to examine whether hyperoxia impairs dia...

journal_title：Critical care medicine

authors： Nishina K,Mikawa K,Shiga M,Kodama S,Kagawa T,Maekawa N,Obara H

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To examine the efficacy of iontophoretic delivery of calcium to experimental hydrofluoric acid burns. DESIGN:Prospective, controlled study. SETTING:Institutional laboratory. SUBJECTS:Male nude rats. INTERVENTIONS:For the in vitro experiment, a full-thickness skin from the back was set in a vertical flow-t...

journal_title：Critical care medicine

authors： Yamashita M,Yamashita M,Suzuki M,Hirai H,Kajigaya H

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:Cocaine, which first made its appearance >1,000 yrs ago, is now widely used throughout the world. The physiologic responses to cocaine may cause severe pathologic effects. This review highlights the many critical care challenges resulting from these effects. DESIGN:Historical vignettes, epidemiologic factors...

journal_title：Critical care medicine

authors： Shanti CM,Lucas CE

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:Most knowledge related to the pathophysiology of microcirculation in ischemic stroke comes from experimental research. Unfortunately, data on microcirculation in the human brain are limited, partially as a result of the lack of appropriate investigational techniques. The objective of our study was to test th...

journal_title：Critical care medicine

authors： Pérez-Bárcena J,Goedhart P,Ibáñez J,Brell M,García R,Llinás P,Jiménez C,Ince C

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To determine alterations in intestinal epithelial permeability to solutes in burn injured rats with and without Enterococcus faecalis infection and the role of neutrophils in the intestinal permeability changes. DESIGN:Prospective sham-controlled animal study. SETTING:University research laboratory. SUBJEC...

journal_title：Critical care medicine

authors： Samonte VA,Goto M,Ravindranath TM,Fazal N,Holloway VM,Goyal A,Gamelli RL,Sayeed MM

更新日期：2004-11-01 00:00:00

abstract：:Hypersensitivity reactions are defined as immunologically based adverse reactions to chemicals or medicinal agents. These reactions are common in the intensive care unit and can present as a simple, mildly symptomatic rash or as life-threatening anaphylactic reactions. Hypersensitivity reactions have traditionally bee...

journal_title：Critical care medicine

authors： Kanji S,Chant C

更新日期：2010-06-01 00:00:00

abstract：:Critically ill patients who fear impending death may die suddenly. We studied prospectively the incidence of death in critically ill surgical patients who articulated the fear that they were about to die. Physiologic, environmental, and behavioral correlates which might influence perceptions of impending death were ex...

journal_title：Critical care medicine

authors： Poulton TJ,Butdorf MB

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:To explore the potential value of heart rate variability features for automated monitoring of sedation levels in mechanically ventilated ICU patients. DESIGN:Multicenter, pilot study. SETTING:Several ICUs at Massachusetts General Hospital, Boston, MA. PATIENTS:Electrocardiogram recordings from 40 mechanica...

journal_title：Critical care medicine

authors： Nagaraj SB,McClain LM,Zhou DW,Biswal S,Rosenthal ES,Purdon PL,Westover MB

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Although randomized trials yield less biased estimates of treatment effects than other study designs, unconcealed randomization and lack of blinding can lead to overestimates of the treatment benefit on the order of 15% to 40% on average. In applying the results of clinical trials to patient care, clinicians ...

journal_title：Critical care medicine

authors： Kunz R,Neumayer HH,Khan KS

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To determine whether plasma lipid hydroperoxides may be a useful marker for sepsis. DESIGN:Exploratory, open-label study. SETTING:Critical care unit at a university medical center. PATIENTS:Twelve patients with sepsis syndrome requiring hemodynamic monitoring with pulmonary artery catheters. Seven patients...

journal_title：Critical care medicine

authors： Keen RR,Stella L,Flanigan DP,Lands WE

更新日期：1991-09-01 00:00:00

abstract：:A survey of acute care/blood gas laboratories was conducted through the memberships of the Society of Critical Care Medicine ( SCCM ) and the National Association of Medical Directors of Respiratory Care ( NAMDRC ). Data were obtained from 227 laboratories and analyzed for operational characteristics, personnel, analy...

journal_title：Critical care medicine

authors： Hall JR,Shapiro BA

更新日期：1984-06-01 00:00:00