Abstract：
PURPOSE:To compare the efficacy of heparin-surface-modified (HSM), poly(methyl methacrylate) (PMMA) posterior chamber intraocular lenses (IOLs) with that of unmodified PMMA IOLs in reducing postoperative complications caused by inflammatory reactions after extracapsular cataract extraction in an Asian population. SETTING:Departments of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia, and Tan Tock Seng Hospital, Singapore. METHODS:In a randomized, double-blind study performed at two centers, 51 patients received an HSM PMMA lens and 48, an unmodified PMMA IOL. Cell and pigment deposits were evaluated by slitlamp at 1 to 6 days, 2 to 3 weeks, and 3 to 6 months postoperatively. RESULTS:Significantly more eyes with unmodified IOLs had inflammatory cell deposits than those with HSM IOLs at 3 to 6 months (P < .001) and 12 to 14 months (P = .018) postoperatively. The HSM group also had significantly fewer cell deposits per patient at these two follow-ups. Significantly more eyes in the non-HSM group had pigment deposits 3 to 6 months after surgery (P = .049). One year postoperatively, about 85% of patients in both groups had a best corrected visual acuity of 0.5 or better. CONCLUSION:Heparin surface modification significantly reduced the inflammatory response to PMMA IOLs in an Asian population for at least 12 to 14 months.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Lai YK,Fan RFdoi
10.1016/s0886-3350(96)80170-2subject
Has Abstractpub_date
1996-01-01 00:00:00pages
830-4eissn
0886-3350issn
1873-4502pii
S0886-3350(96)80170-2journal_volume
22 Suppl 1pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract：PURPOSE:To study the safety of irrigation with 5-fluorouracil (5-FU) in the Perfect Capsule sealed-capsule irrigation device (Milvella, Ltd., Epping, Australia). SETTING:St. Erik's Eye Hospital, Stockholm, Sweden. METHODS:Thirty 8-week-old rabbits were divided into 4 groups. Clear lens extraction was performed and th...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2007.05.012
更新日期：2007-09-01 00:00:00
abstract：PURPOSE:To define one possible etiology for the rise in intraocular pressure (IOP) after neodymium: YAG (Nd:YAG) laser capsulotomy and provide information for the continued investigation of this process. SETTING:Laser Center, Eye and Ear Institute, Pittsburgh, Pennsylvania. METHODS:Samples of 1% sodium hyaluronate or...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80315-4
更新日期：1996-07-01 00:00:00
abstract：UNLABELLED:We highlight potential problems and pitfalls in cases of Salzmann nodular degeneration by reporting the case of an 84-year-old man with reduced visual acuity due to particularly extensive bilateral Salzmann nodules and moderate cataracts. Large annular Salzmann lesions were removed by superficial keratectomy...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2015.10.037
更新日期：2015-11-01 00:00:00
abstract：UNLABELLED:A 22-year-old white man presented with photopsia of 3-year duration despite a corrected distance visual acuity of 20/20 in both eyes. Ophthalmic examination revealed multiple irregularly shaped white cortical opacifications of the lens in both eyes but no other significant ocular findings. One year after the...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.06.007
更新日期：2016-07-01 00:00:00
abstract：:Unwanted optical images are noticed by a surprisingly large number of patients following cataract extraction with implantation of posterior chamber intraocular lenses (IOLs). These images are caused by the positioning holes, lens edge, or laser ridge. We studied 550 eyes in which one of seven different IOLs was insert...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(89)80113-0
更新日期：1989-09-01 00:00:00
abstract：PURPOSE:To report a case series of post-phacoemulsification endophthalmitis despite antibiotic prophylaxis with an intracameral injection of a licensed cefuroxime formulation (Aprokam). SETTING:University Hospitals of Pointe-à-Pitre, Guadeloupe, and Fort-de-France, Martinique, French West Indies. DESIGN:Retrospective...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.06.030
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To determine the relation between ablation zone decentration, measured by corneal topography, and visual and refractive outcome, contrast sensitivity, glare, and subjective reports of halos after photorefractive keratectomy (PRK). SETTING:Eye Foundation, University of Missouri-Kansas City School of Medicine. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(96)80305-1
更新日期：1996-07-01 00:00:00
abstract：PURPOSE:To compare visual outcomes in normal and complicated laser in situ keratomileusis (LASIK) flaps constructed with a femtosecond laser. SETTING:Wilford Hall Ambulatory Surgical Center, San Antonio, Texas. DESIGN:Retrospective chart review. METHODS:The main outcome measures were uncorrected distance visual acui...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2015.05.024
更新日期：2015-11-01 00:00:00
abstract：:A 48-year-old man with cataract had uncomplicated phacoemulsification and implantation of a posterior chamber intraocular lens (IOL) into the continuous capsulorhexis. Three years later, part of the capsular bag and a haptic subluxated into the anterior chamber. At the time of repositioning surgery, partial zonular de...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(97)80127-7
更新日期：1997-11-01 00:00:00
abstract：:This study examined resident exposure to and competency in new techniques for cataract removal and intraocular lens (IOL) implantation. A questionnaire was sent to 116 United States ophthalmology program directors and completed by 71. In response to the questionnaire, program directors reported that 95.3% of their gra...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2017.10.014
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:To evaluate the repeatability and reproducibility of anterior chamber volume (ACV) measurements using swept-source 3-dimensional corneal and anterior segment optical coherence tomography (CAS-OCT) and dual Scheimpflug imaging. SETTING:Department of Ophthalmology, Institute of Clinical Medicine, University of T...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.jcrs.2010.08.053
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:To evaluate a commercially available neural network program for calculation of photorefractive keratectomy treatment nomograms. SETTING:University referral refractive surgery clinic. METHODS:PRK/LASIK Brain, a commercial neural network computer program, was trained using the demographics, preoperative clinica...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(98)80043-6
更新日期：1998-07-01 00:00:00
abstract：PURPOSE:To study contrast sensitivity in eyes that had flying-spot excimer laser photorefractive keratectomy (PRK) and to compare a subjective method (Vision Contrast Test System [VCTS] 6500) and an objective method (visual evoked potential [VEP]) of measuring contrast sensitivity. SETTING:Istituto Clinica Oculistica,...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(00)00405-3
更新日期：2000-06-01 00:00:00
abstract：:We present the results of a survey carried out by independent researchers to determine the subjective success rate of a series of excimer laser photorefractive keratectomy procedures to correct myopia. Thirty patients, selected at random from a group of 300, had received treatment to both eyes with a minimum of six mo...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80766-3
更新日期：1994-03-01 00:00:00
abstract：:Interlenticular opacification (ILO) developed 7 months after secondary acrylic piggyback lens implantation in which the anterior lens was placed in the bag. This resulted in glare and a hyperopic shift. Treating the ILO with the neodymium:YAG laser successfully reduced the glare and corrected the hyperopic shift. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)00865-3
更新日期：2001-09-01 00:00:00
abstract：PURPOSE:To evaluate the visual and economic benefits of same-day bilateral cataract surgery versus separate-day bilateral cataract surgery in the United States. SETTING:Private practice, Amarillo, Texas, USA. DESIGN:Prospective controlled nonrandomized clinical trial. METHODS:A cohort of patients having same-day bil...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.07.034
更新日期：2015-04-01 00:00:00
abstract：:We present a case of endocapsular hematoma, a rare form of intraocular hemorrhage that developed in a patient with pseudophakia receiving oral anticoagulants for previous mitral valve replacement and cerebrovascular disease. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.07.011
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:To compare the efficacy and safety of anterior capsulotomy creation with a new selective laser device (CAPSULaser) with those of manual capsulotomies. SETTING:GEMINI Eye Clinic, Zlin, Czech Republic. DESIGN:Prospective case series. METHODS:Patients were placed in cohorts based on age and cataract grade and r...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2018.12.012
更新日期：2019-05-01 00:00:00
abstract：:Anterior stromal pocket hydration was compared with conventional hydration for preventing wound leak after 2.8 mm uniplanar clear corneal incisions (CCIs) in patients having routine cataract surgery. Conventional hydration involves hydration of the lateral walls of the main incision with visible whitening of the strom...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2012.04.019
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of epithelial-disruption collagen crosslinking (CXL) for progressive keratoconus using a corneal disruptor device and a riboflavin solution designed for a transepithelial technique. SETTING:Magna Graecia University Eye Clinic, Catanzaro, Italy. DESIGN:Prospective comparative case seri...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2013.05.022
更新日期：2013-08-01 00:00:00
abstract：UNLABELLED:We describe several simple modifications of the big-bubble technique to improve surgeon comfort and reduce the risk for complications, with emphasis on our ophthalmic viscosurgical device (OVD)-assisted incision technique. By coating the overlying stroma with OVD prior to entering the big bubble, space is ma...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.09.014
更新日期：2011-11-01 00:00:00
abstract：PURPOSE:To assess the safety and effectiveness of an immunotoxin, MDX-RA, designed to inhibit posterior capsule opacification (PCO). SETTING:Eleven private practices in the United States. METHODS:This study comprised 63 eyes of 63 patients having extracapsular cataract extraction by phacoemulsification; these patient...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0886-3350(98)80352-0
更新日期：1998-12-01 00:00:00
abstract：PURPOSE:To evaluate excimer laser photorefractive keratectomy (PRK) for myopia using a repetition rate of 15 Hz instead of 10 Hz. SETTING:The Cornea and Laser Eye Institute, Teaneck, and Department of Ophthalmology, UMDNJ-New Jersey Medical School, Newark, New Jersey, USA. METHODS:Photorefractive keratectomy using a ...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(99)00406-x
更新日期：2000-03-01 00:00:00
abstract：PURPOSE:To compare the long-term refractive effects of small-incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) on the correction of high myopia and astigmatism. SETTING:The Eye and ENT Hospital of Fudan University, Shanghai, China. DESIGN:Retrospective case s...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000075
更新日期：2020-03-01 00:00:00
abstract：:We present a simple, effective technique to remove an intraocular lens (IOL) via a very small incision (2.2 mm). After the IOL is carefully removed from the capsular bag, into the anterior chamber, 2 radial incisions, 35 degrees to 50 degrees apart, are made with a Vannas scissors. This results in 2 IOL pieces (maximu...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.02.036
更新日期：2009-07-01 00:00:00
abstract：PURPOSE:This study sought to assess the frequency of refractive surgery complications in HIV+ individuals and related risk factors. SETTINGS:Multiple centers in the United States. DESIGN:Prospective observational cohort study. METHODS:The U.S. Military HIV Natural History Study is a prospective observational cohort ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jcrs.2019.06.017
更新日期：2019-11-01 00:00:00
abstract：:Postoperative lens capsule opacification is a complication of extracapsular cataract extraction. To avoid this problem, we aspirated the epithelial cells lining the internal surface of the capsular bag. Anterior capsule specimens collected three and six years after the first surgical intervention (extracapsular catara...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80302-1
更新日期：1993-05-01 00:00:00
abstract：:We performed morphometric analysis of the central corneal endothelium on 24 eyes of 19 patients who had had anterior radial keratotomy. The endothelium was analyzed for a variety of parameters, including cell area, perimeter, side lengths, cell shape, and number of sides. Mean, standard deviation, and coefficient of v...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(87)80068-8
更新日期：1987-05-01 00:00:00
abstract：:We report six-month results of the Summit Technology Myopic Keratomileusis Phase I multicenter study. Fifty-seven eyes of 57 patients had keratomileusis to correct high myopia. A microkeratome was used for the primary keratectomy and the excimer laser was used to ablate the stroma of the resected lenticle (cap) or the...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/s0886-3350(13)80648-7
更新日期：1994-11-01 00:00:00
abstract：:A method to measure the power of an intraocular lens (IOL) in situ using an extended range keratometer and a depth measuring apparatus is described. With this method, the IOL power was measured in ten patients with an anterior chamber IOL and in ten patients with a posterior chamber IOL and compared with the labeled p...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(88)80066-x
更新日期：1988-01-01 00:00:00
