Abstract:
PURPOSE:To evaluate a commercially available neural network program for calculation of photorefractive keratectomy treatment nomograms. SETTING:University referral refractive surgery clinic. METHODS:PRK/LASIK Brain, a commercial neural network computer program, was trained using the demographics, preoperative clinical data, surgical parameters, and 1 year postoperative clinical data of 44 patients treated with a Summit Technology excimer laser using a 5.0 mm optical zone. The neural-network derived nomogram was compared with the standard treatment nomogram for each patient. The relative contribution of age, sex, keratometry, and intraocular pressure (IOP) to the predicted nomograms was also assessed. RESULTS:Nomograms produced by the neural network were qualitatively similar to the standard nomogram. The sequence of data entry during training affected the network's predictions. Entry ordered by outcome (as opposed to entry by chronological order) yielded a nomogram that was more consistent with the standard nomogram. However, both outcome- and chronologically ordered network-derived nomograms diverged from the standard nomogram in individual patients, including a subset for whom use of the standard nomogram yielded desired refractive results (within 0.25 diopter of emmetropia). Further analysis of the neural-network-derived nomograms revealed marked sensitivity to sex, age, keratometry readings, and IOP. CONCLUSIONS:Neural networks offer a potential means of individualizing treatment nomograms, to account for patient demographics, preoperative examination, surgeon style, and equipment bias. However, a data set of 44 patients was not sufficient to train the PRK/LASIK Brain network to accurately predict treatment parameters in individual cases in the training set. A larger training set or a different learning algorithm may be required to improve the neural network's performance.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Yang SH,Van Gelder RN,Pepose JSdoi
10.1016/s0886-3350(98)80043-6subject
Has Abstractpub_date
1998-07-01 00:00:00pages
917-24issue
7eissn
0886-3350issn
1873-4502pii
S0886-3350(98)80043-6journal_volume
24pub_type
杂志文章abstract::A poly(methyl methacrylate)(PMMA) intraocular lens (IOL) dislocated into the vitreous cavity in 2 patients after a neodymium:YAG (Nd:YAG) laser posterior capsulotomy. In Case 1, the capsulotomy was performed 19 months after extracapsular cataract extraction (ECCE) and sulcus fixation of an IOL. Six months later the IO...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(98)80182-x
更新日期:1998-11-01 00:00:00
abstract:UNLABELLED:Presbyopia is the most common refractive disorder for people older than 40 years. It is characterized by a gradual and progressive decrease in accommodative amplitude. Many surgical procedures for the correction of presbyopia exist, with additional procedures on the horizon. This review describes the prevale...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,评审
doi:10.1016/j.jcrs.2016.05.003
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To compare the variance in manifest refraction spherical equivalent (MRSE) after photorefractive keratectomy (PRK) with mitomycin-C (MMC), PRK without MMC, and laser in situ keratomileusis (LASIK) for the treatment of myopic astigmatism. SETTING:Jules Stein Eye Institute, University of California, Los Angeles,...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.02.048
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To compare neodymium:YAG (Nd:YAG) laser effects on acrylic, silicone, and poly(methyl methacrylate) (PMMA) intraocular lens (IOL) polymers. METHODS:Ten Nd:YAG laser exposures were produced in each of 6 implantation-quality acrylic (Alcon MA60BM), silicone (Staar AQ1016), and PMMA (Alcon MC60BM) IOLs under iden...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(99)80014-5
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To document keratocyte distribution and changes with age in the cellular network of the human cornea in vivo. SETTING:Department of Ophthalmology, University of Rostock, Rostock, Germany. METHODS:Forty-nine eyes of 31 healthy subjects of various ages were examined with a modified Microphthal scanning-slit con...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(01)01227-5
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:To describe 7 patients who developed ectasia following laser in situ kerato-mileusis (LASIK). SETTING:Instituto de la Visión, Buenos Aires, Argentina. METHODS:In this retrospective study of 7 patients, visual acuity, refraction, pachymetry, and corneal topography were examined before and after the refractive ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(01)00799-4
更新日期:2001-09-01 00:00:00
abstract::We describe the intraoperative difficulties encountered in cases of ocular Stevens-Johnson syndrome as a result of a poor ocular surface, the presence of symblepharon, and varying degrees of corneal opacity with secondary poor visibility of anterior segment structures. Modifications to the standard phacoemulsification...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2016.09.012
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To evaluate ocular penetration of topically applied linezolid, a new antibiotic agent targeted against gram-positive organisms. SETTING:Laboratory of Pharmacology, University Hospital of Strasbourg, Strasbourg, France. METHODS:New Zealand White rabbits were divided into 3 equal groups. One drop of 50 microL (...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2009.09.036
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To validate changes in intraocular pressure (IOP) after phacoemulsification with intraocular lens (IOL) implantation without pressure-lowering surgery in previously unoperated eyes of normal and glaucoma patients. SETTING:University Eye Clinic, Otto-von-Guericke-University, Magdeburg, Germany. DESIGN:Cohort s...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2011.11.034
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of photorefractive keratectomy (PRK) with intraoperative application of mitomycin-C (MMC). SETTING:Yonsei Eye Center, Seoul, South Korea. METHODS:This retrospective noncomparative case series included 536 patients (1011 eyes) who had had PRK with intraoperative application ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2005.05.027
更新日期:2005-12-01 00:00:00
abstract:UNLABELLED:We describe a technique for sutureless intrascleral fixation of a 3-piece intraocular lens (IOL) and custom silicone iris prosthesis complex to address the optical and functional issues of aphakia and aniridia, as well as to restore excellent cosmesis. The 3-piece IOL is anchored to the iris prosthesis using...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.09.015
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:To determine whether the keratometric and refractive surgical effects of paired intrastromal corneal ring segments (ICRS) depend on their alignment relative to steep and flat topographic meridians. SETTING:St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom. DESIGN:Comparative ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2012.04.024
更新日期:2012-08-01 00:00:00
abstract::Multifocal intraocular lenses (MIOLs) have been designed to provide better uncorrected near visual acuity than monofocal IOLs. However, the increase in depth of focus is combined with a significant decrease in contrast sensitivity and glare. We implanted a new zonal-progressive MIOL (AMO Array) in 31 eyes of 25 patien...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章
doi:10.1016/s0886-3350(13)80217-9
更新日期:1995-09-01 00:00:00
abstract:PURPOSE:To develop and test the validity of a surgical competency assessment tool for simulated small-incision cataract surgery (SICS). SETTING:Participating ophthalmologists contributed from 8 countries. DESIGN:Qualitative and quantitative development and evaluation of face and content validity of an assessment rubr...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcrs.2019.04.010
更新日期:2019-09-01 00:00:00
abstract::A 77-year-old woman had uneventful phacoemulsification. Postoperative examination revealed that chloramphenicol ointment instilled in the conjunctival fornix had entered the anterior chamber and smeared the intraocular lens (IOL). Immediate surgical removal of the ointment with IOL exchange was performed. The eye sett...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(02)01503-1
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To determine whether riboflavin and ultraviolet-A (UVA) corneal crosslinking can be used as an alternative therapy to prevent the progression of keratectasia. SETTING:Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland, and a private clinic, Athens, Greece. METHODS:Corneal crosslinking was pe...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2007.07.028
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To present a series of cases in which the four-flanged technique was used in the management of in-the-bag intraocular lens (IOL) subluxation. SETTING:Shamir medical center, Israel. DESIGN:Retrospective cohort analysis. METHODS:Included were consecutive cases with secondary IOL subluxation that underwent scle...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1097/j.jcrs.0000000000000474
更新日期:2020-11-02 00:00:00
abstract::We report a case of Candida infection after laser in situ keratomileusis (LASIK) and review the literature for reports of post-LASIK fungal infections. Risk factors may include postoperative surgical intervention and extended use of topical steroids. ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(03)00217-7
更新日期:2003-10-01 00:00:00
abstract:PURPOSE:To use optical coherence tomography (OCT) angiography and a split-spectrum amplitude-decorrelation angiography algorithm to evaluate the changes in the macular vascular system after uncomplicated phacoemulsification. SETTING:Department of Ophthalmology, Eye and and Ear, Nose, and Throat Hospital of Fudan Unive...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2018.02.014
更新日期:2018-04-01 00:00:00
abstract::The current trend toward implantation of posterior chamber lenses within the capsular bag rather than the ciliary sulcus seems logical in light of the increasing evidence of uveal damage from sulcus fixated posterior chamber lenses. However, long-term, successful capsular bag fixation has not been demonstrated with cu...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(87)80040-8
更新日期:1987-07-01 00:00:00
abstract:PURPOSE:To demonstrate an analytical method to compare the actual and intended refraction after cataract surgery that allows incorporation of refractive surgical effects. SETTING:Corneal and External Eye Disease Service, Royal Liverpool University Hospital, Liverpool, United Kingdom. METHODS:The actual postoperative ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(03)00418-8
更新日期:2003-11-01 00:00:00
abstract::A 56-year-old woman was referred with recurrent interface infiltration and hypopyon after astigmatic laser in situ keratomileusis (LASIK) on a corneal graft. Pseudomonas aeruginosa was isolated as the causative pathogen. Penetrating keratoplasty had been performed 2 years before refractive surgery. After the antibioti...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2003.05.001
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To determine the relation between ablation zone decentration, measured by corneal topography, and visual and refractive outcome, contrast sensitivity, glare, and subjective reports of halos after photorefractive keratectomy (PRK). SETTING:Eye Foundation, University of Missouri-Kansas City School of Medicine. ...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章
doi:10.1016/s0886-3350(96)80305-1
更新日期:1996-07-01 00:00:00
abstract::Cataract surgery can be safely performed in patients with Stevens-Johnson syndrome (SJS) with visually significant cataracts. Maintaining ocular surface integrity improves the prognosis of cataract surgery in this high-risk population. We present the outcome of cataract surgery in a retrospective chart review of 3 eye...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2004.07.023
更新日期:2005-04-01 00:00:00
abstract::Seven patients with unsuspected unilateral axial myopia developed a cataract in the longer eye. Vision deteriorated in all cases between the ages of 40 and 55 years. Bilateral axial length measurements were necessary for the diagnosis and revealed a difference of 4.5 mm to 6.7 mm between the two eyes. Five cases had a...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(89)80090-2
更新日期:1989-05-01 00:00:00
abstract:PURPOSE:To correlate the observed fluorescence spectrum with the depth of ablation during 193 nm argon-fluoride excimer laser ablation of chemically damaged corneas. SETTING:Laser facility, Cedars-Sinai Medical Center, Los Angeles, California, USA. METHODS:Three cadaver New Zealand white rabbit corneas were exposed t...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(02)01361-5
更新日期:2002-10-01 00:00:00
abstract:PURPOSE:To determine whether preserved human amniotic membrane can reduce corneal haze and keratocyte apoptosis induced by excimer laser photoablation in rabbit corneas. METHODS:Excimer photoablation was performed bilaterally in 30 rabbits with a 6.0 mm ablation zone and 120 microm depth using the VISX Star laser with...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(00)00467-3
更新日期:2001-02-01 00:00:00
abstract::A monolayer of proliferating lens epithelium on the anterior surface of an intraocular lens was found cytologically and confirmed histologically in a postmortem examination of one eye of a 57-year-old man. The man had had extracapsular cataract surgery five years earlier. This pathological finding confirms observation...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80353-7
更新日期:1993-11-01 00:00:00
abstract:PURPOSE:To describe a novel method for calculating intraocular lens (IOL) power after myopic laser in situ keratomileusis (LASIK) without using the inaccuracies of the post-LASIK corneal power. SETTING:Department of Ophthalmology, Wake Forest University Eye Center, Wake Forest University School of Medicine, Winston Sa...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2005.12.140
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:To compare the intraoperative behavior and postoperative outcomes of posterior capsule dehiscence during phacoemulsification and during manual extracapsular cataract extraction (ECCE). SETTING:L.V. Prasad Eye Institute, Hyderabad, India. METHODS:This study was a retrospective chart review of consecutive cases...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(02)01696-6
更新日期:2003-03-01 00:00:00