Abstract：
PURPOSE:To study the safety of irrigation with 5-fluorouracil (5-FU) in the Perfect Capsule sealed-capsule irrigation device (Milvella, Ltd., Epping, Australia). SETTING:St. Erik's Eye Hospital, Stockholm, Sweden. METHODS:Thirty 8-week-old rabbits were divided into 4 groups. Clear lens extraction was performed and the Perfect Capsule was applied in 1 eye in Groups 1, 2 and 3. The sealed system was flushed with balanced salt solution (BSS) in Group 1, 5-FU 50 mg/mL in Group 2, and 5-FU followed by BSS in Group 3. In Group 4, the Perfect Capsule was not applied; instead, 0.2 mL of 5-FU was instilled in the capsule and left there for 30 seconds. An endothelial cell count and pachymetry were performed preoperatively and 24 hours postoperatively. At 24 or 48 hours (half of each group at each time point), the rabbits were killed and the retina and trabecular meshwork histopathologically examined. The endothelial cell count and pachymetry were compared between the Perfect Capsule eye and the control eye in Group 1. RESULTS:There was no difference between the groups in endothelial cell count (P = .96) or pachymetry (P = .32). Histologic evaluation showed no damage from the 5-FU. The comparison between eyes in Group 1 showed that the use of the Perfect Capsule did not cause more endothelial cell loss (P = .86) or increase pachymetry more (P = .28) than in the control eye. CONCLUSION:Irrigation with 5-FU 50 mg/mL in the sealed-capsule irrigation device was safe and caused no apparent damage to the adjacent intraocular tissues.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Abdelwahab MT,Kugelberg M,Seregard S,Zetterström Cdoi
10.1016/j.jcrs.2007.05.012subject
Has Abstractpub_date
2007-09-01 00:00:00pages
1619-23issue
9eissn
0886-3350issn
1873-4502pii
S0886-3350(07)00895-4journal_volume
33pub_type
杂志文章abstract：UNLABELLED:We describe a recently developed chopper, the retrochopper, and a technique for managing black and brunescent cataracts. The technique enables the surgeon to effectively disassemble the nucleus and perform a safe procedure with a short learning curve. FINANCIAL DISCLOSURE:No author has a financial or propri...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2013.03.015
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To study the intraoperative performance and postoperative outcomes of Cionni modified capsule tension ring (CTR) and intraocular lens (IOL) implantation in the capsular bag in pediatric eyes with ectopia lentis. SETTING:John A. Moran Eye Center, Salt Lake City, Utah, USA. METHODS:Thirty-five eyes (22 children...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.04.044
更新日期：2008-09-01 00:00:00
abstract：PURPOSE:To evaluate the intraexaminer repeatability and the interobserver reproducibility of manifest refraction. SETTING:Tertiary referral center. DESIGN:Retrospective study. METHODS:Patients attending at least 2 preoperative refractions before undergoing subsequent refractive surgery were included. All manifest re...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000343
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To examine the hypothesis that removing the center of the posterior capsule would prevent posterior capsular opacification (PCO). SETTING:Department of Ophthalmology, University Hospital Antwerp, Belgium. METHODS:A posterior continuous curvilinear capsulorhexis (CCC) was done before intraocular lens (IOL) imp...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80068-x
更新日期：1996-11-01 00:00:00
abstract：PURPOSE:To report results of the National French Observational Database for Endophthalmitis (Observatoire National Des Endophtalmies [ONDE]). SETTING:Departments of ophthalmology at universities, general hospitals, and private clinics. METHODS:In this multicenter national interventional case series, data were collect...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jcrs.2008.10.018
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:To compare the efficiencies of the operative procedures and the reductions in postoperative corneal endothelial cell density (ECD) after cataract surgery using 2 different phacoemulsification tips and their associated cassettes and tubing. SETTING:Wolfe Clinic, Marshalltown, Iowa, USA. METHODS:A randomized pr...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(99)00201-1
更新日期：1999-10-01 00:00:00
abstract：:Surgery is a major source of errors in patient care. Preventing complications from surgical errors in the operating room is estimated to lead to reduction of up to 41,846 readmissions and save $620.3 million per year. It is now established that poor technical skill is associated with an increased risk of severe advers...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000322
更新日期：2020-07-13 00:00:00
abstract：PURPOSE:To evaluate the contribution of Fourier analysis of videokeratographic data in the diagnosis of subclinical keratoconus and keratoconus. SETTING:Eye Institute of Thrace, Democritus University, Alexandroupolis, Greece. DESIGN:Observational case series. METHODS:The following Pentacam-derived parameters, result...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.01.049
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To evaluate the results of the first blue light-filtering photochromic intraocular lens (IOL) and compare them with those of a regular yellow blue light-filtering IOL and a clear ultraviolet-filtering IOL in human eyes under various lighting conditions. SETTING:Beijing Tongren Eye Center, Beijing Tongren Hospi...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2010.07.024
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:To determine the physical and mechanical conditions of an impacting air bag that causes corneal rupture in a post-radial keratotomy (RK) eye using a simulation model of the human eye. SETTING:Numerical simulation study on a computer. METHODS:The simulations were performed by a computer using the finite elemen...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)00966-x
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:To assess the outcomes of intrastromal ring segment (Intacs, Addition Technology) implantation for keratoconus using the femtosecond laser. SETTING:Kudret Eye Hospital, Ankara, Turkey. METHODS:In a retrospective noncomparative case series, 118 eyes of 69 patients with keratoconus who had Intacs segments impla...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.08.032
更新日期：2006-12-01 00:00:00
abstract：:Subluxated cataractous and clear lenses are commonly treated by limbal or pars plana lensectomy followed by primary or secondary intraocular lens (IOL) implantation. Adjunctive capsular prosthetic devices have facilitated lens removal and IOL centration in these challenging cases but have also added complexity and pot...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.05.019
更新日期：2009-10-01 00:00:00
abstract：PURPOSE:To compare the incidence of posterior capsule rupture and vitreous loss during phacoemulsification with and without the use of an anterior chamber maintainer (ACM) SETTING: Aristotle University Eye Clinic, Thessaloniki, Greece. METHODS:The surgical records of patients who had phacoemulsification by experienced...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/S0886-3350(03)00584-4
更新日期：2004-02-01 00:00:00
abstract：PURPOSE:To measure the change in visual acuity and vision-related quality of life in patients with both age-related cataract and bilateral age-related macular degeneration (AMD) after cataract surgery. SETTING:Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. DESI...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.09.046
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To evaluate the effect of removal and/or exchange of intrastromal corneal ring segments (ICRS, Intacs); specifically the risk factors, degree of reversibility, and visual outcomes. SETTING:Gimbel Eye Centres, Calgary, Edmonton, and Vancouver, Canada. METHODS:Prospective cohort data were collected on 71 eyes t...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)01172-5
更新日期：2002-04-01 00:00:00
abstract：:Collagen shields made of porcine collagen were placed in a solution containing tobramycin sulfate (40 or 200 mg/ml) for five minutes, then applied to rabbit eyes. One, four, or eight hours after application, the corneas, aqueous humor samples, and shields were assayed for antibiotic. At all intervals, the concentratio...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(88)80006-3
更新日期：1988-09-01 00:00:00
abstract：PURPOSE:To determine whether the yellow filters often used for glare reduction influence retinal straylight measured in healthy eyes. SETTING:Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium. DESIGN:Prospective case series. METHODS:For each eye, the spherical equivalent (SE) was determined u...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2017.06.033
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:To compare the refractive results of laser astigmatic treatment in eyes in which the astigmatic axes of the eye and laser are aligned by limbal marking at the 6 o'clock position and in eyes that are not marked. SETTING:University Hospital and Clinics, Madison, Wisconsin, USA. METHODS:This retrospective study ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(00)00695-7
更新日期：2000-12-01 00:00:00
abstract：PURPOSE:To validate clinically in a normal healthy population an algorithm to correct the error in the keratometric estimation of corneal power based on the use of a variable keratometric index of refraction (n(k)). SETTING:Medimar International Hospital (Oftalmar) and University of Alicante, Alicante, Spain. DESIGN:...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2012.03.026
更新日期：2012-08-01 00:00:00
abstract：:Cataract surgery can be safely performed in patients with Stevens-Johnson syndrome (SJS) with visually significant cataracts. Maintaining ocular surface integrity improves the prognosis of cataract surgery in this high-risk population. We present the outcome of cataract surgery in a retrospective chart review of 3 eye...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2004.07.023
更新日期：2005-04-01 00:00:00
abstract：:Visual acuity and contrast sensitivity after cataract surgery were evaluated in best-case eyes that received a Storz bifocal zonal intraocular lens (IOL) or a 3M diffractive multifocal IOL. A group of eyes with a monofocal IOL was used as a control. Postoperatively, all eyes had a best corrected visual acuity of 20/40...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80536-6
更新日期：1995-07-01 00:00:00
abstract：:Penetrating keratoplasty in the presence of a perforated cornea is a relatively common and difficult surgical problem. In the worst scenario, there may be extrusion of ocular contents during trephination. Two cases of perforated corneas are presented in which a new technique was used to close the perforation and norma...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2004.10.060
更新日期：2005-05-01 00:00:00
abstract：:Intraocular metallic-appearing foreign bodies in the anterior segment were seen in six eyes after cataract extraction by two-handed phacoemulsification. These fragments produced no symptoms and had no clinically significant effect on visual function. Similar-appearing foreign bodies were experimentally produced by app...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80078-2
更新日期：1996-11-01 00:00:00
abstract：:Anterior segment optical coherence tomography is a new method to explore the anterior chamber. The target can be focused and defocused with positive or negative lenses to reproduce the conditions of natural accommodation. We studied accommodation in an albino patient because the absence of pigment allows the infrared ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2003.12.043
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:To evaluate ocular penetration of topically applied linezolid, a new antibiotic agent targeted against gram-positive organisms. SETTING:Laboratory of Pharmacology, University Hospital of Strasbourg, Strasbourg, France. METHODS:New Zealand White rabbits were divided into 3 equal groups. One drop of 50 microL (...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.09.036
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:Iris intraocular implants were developed to manage congenital or traumatic iris defects. However, they are also used to change the color of patient eyes. The aim of this retrospective series was to report complications in patients managed in France after cosmetic implantation. SETTING:Ophthalmological institut...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000032
更新日期：2020-01-01 00:00:00
abstract：:Phototherapeutic keratectomy (PTK) was performed to treat preexisting silent epithelial basal membrane dystrophy 1 month after laser in situ keratomileusis in 2 patients (4 eyes). The symptoms resolved dramatically during the follow-up period, with the patients reporting an immediate subjective visual improvement. At ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.11.004
更新日期：2009-02-01 00:00:00
abstract：:We report a case of bilateral infectious keratitis occurring as a complication of bilateral simultaneous laser in situ keratomileusis enhancement procedures. Corneal scraping from the interface of both eyes grew Staphylococcus aureus. The infection cleared after treatment with fortified cefazolin, fortified gentamicin...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)01232-9
更新日期：2002-04-01 00:00:00
abstract：PURPOSE:To evaluate and compare the incidence of cyanopsia using the neutralization method in eyes in which clear or yellow intraocular lenses (IOLs) were implanted. SETTING:Miyata Eye Clinic, Hiroshima, Japan. DESIGN:Retrospective comparative study. METHODS:Patients who had cataract surgery with the implantation of...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.07.040
更新日期：2015-04-01 00:00:00
abstract：PURPOSE:To assess whether laser in situ keratomileusis (LASIK) assisted by corneal topography can successfully treat corneal irregularities or irregular astigmatism in patients with previous ocular surgery or ocular trauma. SETTING:University Eye Hospital, Klinikum Mannheim, Mannheim, Germany. METHODS:In a prospectiv...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(98)80196-x
更新日期：1998-02-01 00:00:00
