Abstract：
:Collagen shields made of porcine collagen were placed in a solution containing tobramycin sulfate (40 or 200 mg/ml) for five minutes, then applied to rabbit eyes. One, four, or eight hours after application, the corneas, aqueous humor samples, and shields were assayed for antibiotic. At all intervals, the concentration of antibiotic in the corneas and aqueous humor samples exceeded the mean inhibitory concentration for tobramycin, as determined for most strains of Pseudomonas. Shields immersed in 200 mg/ml tobramycin produced significantly higher concentrations of antibiotic in the cornea at one hour than subconjunctival injections of tobramycin (20 mg) (P = .0001). Shields immersed in 40 mg/ml tobramycin produced higher, although not significantly higher, concentrations of antibiotic in the cornea at one hour than subconjunctival injections of tobramycin (20 mg) (P = .318). Shields immersed in commercially available tobramycin drops or injectable tobramycin solution (40 mg/ml) caused no epithelial damage visible by slitlamp examination. Collagen shields containing antibiotics can serve as a vehicle for drug delivery and may prove superior to current methods for preoperative and postoperative antibiotic prophylaxis and the initial treatment of bacterial keratitis.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Unterman SR,Rootman DS,Hill JM,Parelman JJ,Thompson HW,Kaufman HEdoi
10.1016/s0886-3350(88)80006-3subject
Has Abstractpub_date
1988-09-01 00:00:00pages
500-4issue
5eissn
0886-3350issn
1873-4502pii
S0886-3350(88)80006-3journal_volume
14pub_type
杂志文章abstract：PURPOSE:To compare the long-term longitudinal visual acuity outcomes after cataract surgery in eyes with age-related macular degeneration (AMD) at surgery and eyes without comorbidity. SETTING:University-based eye clinic. DESIGN:Longitudinal cohort study. METHODS:Patients having cataract surgery were evaluated over ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.09.041
更新日期：2012-03-01 00:00:00
abstract：:We present a series of nine cases involving primary intraocular lens implantation in congenital cataracts. Because of the problems encountered with the technique used in the earlier cases, we developed a new surgical technique that may be described as primary epilenticular posterior chamber lens implantation followed ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(88)80088-9
更新日期：1988-03-01 00:00:00
abstract：:A retrospective analysis of 40 cases of sulcus-fixated one-piece poly(methyl methacrylate) posterior chamber lenses revealed ten cases (25%) that demonstrated oval deformation of the pupil, similar to the condition associated with anterior chamber lenses. This complication was not noted until several weeks after surge...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80803-6
更新日期：1990-07-01 00:00:00
abstract：:Recently, scleral fixation has been used in posterior chamber intraocular lens implantation in the absence of the posterior capsule. Fixation is achieved with a suture through the ciliary sulcus and sclera at a horizontal or vertical position. To achieve good functional results, the optical portion of the lens must li...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80585-8
更新日期：1994-05-01 00:00:00
abstract：PURPOSE:To identify preoperative and intraoperative factors associated with a capsule complication; that is, a capsule tear or a zonular dehiscence during cataract surgery. SETTING:Ten ophthalmic surgery departments in Sweden. METHODS:A retrospective review of files of patients with a capsule complication and control...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jcrs.2009.05.026
更新日期：2009-10-01 00:00:00
abstract：PURPOSE:To assess whether laser in situ keratomileusis (LASIK) assisted by corneal topography can successfully treat corneal irregularities or irregular astigmatism in patients with previous ocular surgery or ocular trauma. SETTING:University Eye Hospital, Klinikum Mannheim, Mannheim, Germany. METHODS:In a prospectiv...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(98)80196-x
更新日期：1998-02-01 00:00:00
abstract：PURPOSE:To evaluate how visual acuities at different distances correlate with results from defocus curves. SETTING:Department of Ophthalmology and Institute of Medical Physics, University of Vienna, Medical School, Vienna, and Department of Ophthalmology, Krankenhaus St. Pölten, St. Pölten, Austria. METHODS:This stud...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(02)01317-2
更新日期：2002-11-01 00:00:00
abstract：PURPOSE:To compare the visual, refractive, and adverse outcomes of femtosecond laser-assisted cataract surgery and conventional phacoemulsification cataract surgery. SETTING:Cataract surgery clinics in 9 European countries and Australia (femtosecond-assisted) and 18 European countries and Australia (conventional). DE...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.10.013
更新日期：2016-12-01 00:00:00
abstract：:We describe 2 complications of sequential keratorefractive and vitreoretinal surgery not previously reported. Epithelial ingrowth occurred in 1 patient who experienced laser in situ keratomileusis flap dehiscence and replacement during vitreoretinal surgery. In the second patient, a flap could not be created with a mi...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.05.038
更新日期：2006-12-01 00:00:00
abstract：:A prospective randomized study was performed involving 200 patients divided into four groups: (1) Healon aspirated, (2) Amvisc aspirated, (3) Viscoat aspirated, and (4) Viscoat not aspirated. Postoperative intraocular pressures were measured at 4, 8, and 24 hours, two to three days, and one month. Significant differen...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(89)80060-4
更新日期：1989-07-01 00:00:00
abstract：PURPOSE:To evaluate an outbreak of infectious keratitis after laser in situ keratomileusis (LASIK) at a single laser center in Japan. SETTING:Tokyo Dental College, Chiba, Japan. DESIGN:Case series. METHODS:Relevant demographic and clinical data were obtained from case records using a standardized multicenter questio...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jcrs.2010.11.034
更新日期：2011-05-01 00:00:00
abstract：:A multizone/multipass photorefractive keratectomy (MP-PRK) technique was used to treat 315 eyes with the 193 nm VISX 20/20 excimer laser. Algorithms were developed to treat the full range of myopia, including 170 low myopic eyes (-1.0 to -6.0 diopters [D]), 105 moderately myopic eyes (-6.0 to -10.0 D), and 40 highly m...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80559-7
更新日期：1995-11-01 00:00:00
abstract：PURPOSE:To evaluate a commercially available neural network program for calculation of photorefractive keratectomy treatment nomograms. SETTING:University referral refractive surgery clinic. METHODS:PRK/LASIK Brain, a commercial neural network computer program, was trained using the demographics, preoperative clinica...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(98)80043-6
更新日期：1998-07-01 00:00:00
abstract：PURPOSE:To assess the degree of capsular bag opacification in human cadaver eyes with silicone intraocular lenses (IOLs), specifically comparing the differences between round-edged IOLs and modern square-edged IOLs. SETTING:John A. Moran Eye Center, University of Utah, USA. DESIGN:Experimental study. METHODS:The eye...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.10.058
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:To evaluate ocular penetration of topically applied linezolid, a new antibiotic agent targeted against gram-positive organisms. SETTING:Laboratory of Pharmacology, University Hospital of Strasbourg, Strasbourg, France. METHODS:New Zealand White rabbits were divided into 3 equal groups. One drop of 50 microL (...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.09.036
更新日期：2010-03-01 00:00:00
abstract：:Two patients with active iritis developed cataracts and had successful cataract surgery with implantation of a Collamer (Staar Surgical, AG) intraocular lens (IOL). Both patients developed severe bilateral uveitis, which in 1 patient was refractory to control. Different IOL materials have been used in iritis patients ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00329-8
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:To explore the use of the Pulsar Z1 solid-state 213 nm photorefractive laser platform in topography-guided transepithelial photorefractive keratectomy (PRK) for irregular astigmatism. SETTING:Moorfields Eye Hospital, London, United Kingdom. DESIGN:Prospective clinical case series. METHODS:Patients with irreg...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2012.08.056
更新日期：2013-01-01 00:00:00
abstract：UNLABELLED:We present the case of an 81-year-old man with pseudoexfoliation syndrome (PXF) in whom spontaneous bilateral anterior partial in-the-bag intraocular lens (IOL) dislocation was diagnosed following a routine dilated examination that demonstrated only mild pseudophacodonesis with no evidence of subluxation. Un...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.07.008
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:To assess the repeatability and validity of lens densitometry derived from the Pentacam Scheimpflug imaging system. SETTING:Eye Clinic, Queensland University of Technology, Brisbane, Australia. METHODS:This prospective cross-sectional study evaluated 1 eye of subjects with or without cataract. Scheimpflug mea...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.03.017
更新日期：2009-07-01 00:00:00
abstract：:Advances in technique and equipment have led to a significant increase in the popularity of phacoemulsification and have increased its safety and efficiency. We describe a technique, phakonit, in which the lens is emulsified through a 0.9 mm clear corneal temporal incision. A cortical wash with bimanual irrigation/asp...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)00922-1
更新日期：2001-10-01 00:00:00
abstract：:We report a case of nanophthalmos with intractable secondary glaucoma. Bilateral cataract extraction with intraocular lens implantation was used as definitive treatment for the chronic angle-closure glaucoma. The changes in angle and ciliary body anatomy were well documented with preoperative and postoperative Pentaca...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.02.051
更新日期：2006-06-01 00:00:00
abstract：:A 73-year-old woman with bilateral previous radial keratotomies (RK) and symptomatic cataracts was referred. The uncorrected distance visual acuity (UDVA) was 0.24 logarithm of the minimum angle of resolution (logMAR) in the left eye and 0.32 logMAR in the left eye. The American Society of Cataract and Refractive Surg...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2018.06.005
更新日期：2018-08-01 00:00:00
abstract：:This case outlines the phacoemulsification technique used to overcome the challenge of the hyperdeep anterior chamber, weak zonules, abnormal anterior capsule, and large capsular bag. Key steps included trypan blue staining of the anterior capsule, a large capsulorhexis, prolapse of the nucleus into the anterior chamb...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.12.143
更新日期：2006-07-01 00:00:00
abstract：:We present 2 cases of toric intraocular lens implantation for keratoconus: A 55-year-old man with forme fruste keratoconus with a preoperative uncorrected distance visual acuity (UDVA) of 20/800 and a refraction of -6.50-3.00x135 and a 46-year-old man with a claw-shaped topographic pattern, a family history of keratoc...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.05.043
更新日期：2009-11-01 00:00:00
abstract：PURPOSE:To determine whether residual myopia after primary laser-assisted subepithelial keratectomy (LASEK) can be corrected by repeated LASEK and whether this procedure is safe and effective. SETTING:University Eye Clinic, University of Regensburg, Regensburg, Germany. METHODS:Laser-assisted subepithelial keratectom...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00253-0
更新日期：2003-07-01 00:00:00
abstract：PURPOSE:To determine the effectiveness of a single radial suture placement in 2 clear corneal incision (CCI) configurations in preventing inflow of bacterial-sized particles. SETTING:Wilmer Eye Institute, Baltimore, Maryland, USA. DESIGN:Experimental study. METHODS:Ten human globes were used. Two 25-gauge needles co...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.11.042
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:To evaluate findings of reverse pupillary block after scleral-fixated sutured posterior chamber intraocular lens (PC IOL) implantation using anterior segment optical coherence tomography (AS-OCT) and report a possible association with postoperative complications. SETTING:Department of Ophthalmology, Kanazawa U...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.04.030
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To evaluate the influence of cataract morphology on the functional vision of patients with age-related cataract and normal macular function and compare subjectively perceived functional impairments to distance visual acuity, reading acuity, and maximum reading speed between cataract types. SETTING:Department o...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2004.01.038
更新日期：2004-09-01 00:00:00
abstract：PURPOSE:To evaluate the visual results and complications of angle-supported phakic intraocular lenses (IOLs) to correct myopia associated with early-stage keratoconus. SETTING:Private practice, Siena, Italy. METHODS:In a prospective noncomparative single-surgeon interventional case series, outcomes in 12 consecutive ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00346-8
更新日期：2003-08-01 00:00:00
abstract：:Most surgical procedures involving the anterior segment of the eye disrupt the normal organization of corneal innervation. Since denervation of the cornea results in impaired epithelial wound healing, increased epithelial permeability, decreased epithelial metabolic activity, and loss of cytoskeletal structures associ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,评审
doi：10.1016/s0886-3350(98)80237-x
更新日期：1998-10-01 00:00:00
