Physostigmine: going ... going ... gone? Two cases of central anticholinergic syndrome following anaesthesia and its treatment with physostigmine.

Abstract:

:Two patients presented with very different signs of central anticholinergic syndrome following general anaesthesia for which they had received premedication with hyoscine. Both responded dramatically to 1 mg of intravenous (i.v.) physostigmine, which produced a rapid return to a normal level of consciousness. The aetiology of central anticholinergic syndrome is multi-factorial, but the diagnosis should be considered in all patients who demonstrate abnormal post-anaesthetic awakening. It is recommended that 1 mg of intravenous physostigmine is a safe and effective treatment for central anticholinergic syndrome, and that a supply of this important drug must be kept readily available in the recovery area of the operating theatre department.

journal_name

Eur J Anaesthesiol

authors

Martin B,Howell PR

doi

10.1046/j.1365-2346.1997.00128.x

subject

Has Abstract

pub_date

1997-07-01 00:00:00

pages

467-70

issue

4

eissn

0265-0215

issn

1365-2346

journal_volume

14

pub_type

杂志文章
  • Nutrition support and treatment of motility disorders in critically ill patients - results of a survey on German intensive care units.

    abstract:BACKGROUND AND OBJECTIVE:To evaluate the current clinical attitude in enteral nutrition support and motility disorders in adult critically ill patients on German intensive care units. METHODS:A total of 1493 questionnaires, including 25 items on the medical environment, treatment of motility disorders and enteral nutr...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021507002657

    authors: Röhm KD,Schöllhorn T,Boldt J,Wolf M,Papsdorf M,Piper SN

    更新日期:2008-01-01 00:00:00

  • Development of a specific algorithm to guide haemostatic therapy in children undergoing cardiac surgery: a single-centre retrospective study.

    abstract:BACKGROUND:Although rotational thromboelastometry (ROTEM) is increasingly used to guide haemostatic therapy in a bleeding patient, there is a paucity of data guiding its use in the paediatric population. OBJECTIVE:The objective of this study is to develop an algorithm on the basis of ROTEM values obtained in our paedi...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000179

    authors: Faraoni D,Willems A,Romlin BS,Belisle S,Van der Linden P

    更新日期:2015-05-01 00:00:00

  • Ropivacaine 0.1% with fentanyl 2 microg mL(-1) by epidural infusion for labour analgesia.

    abstract:BACKGROUND AND OBJECTIVE:To evaluate the efficacy of 0.1% ropivacaine with fentanyl 2 microg mL(-1) via epidural for analgesia in labour. METHODS:In a randomized study, 80 nulliparous parturients in labour had epidural analgesia initiated with 0.2% ropivacaine and fentanyl and were then randomized to receive either 0....

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s0265021504000031

    authors: Atienzar MC,Palanca JM,Borras R,Esteve I,Fernandez M,Miranda A

    更新日期:2004-10-01 00:00:00

  • Low-dose fentanyl analgesia modified by calcium channel blockers in cardiac surgery.

    abstract::The hypothesis that calcium channel blockers can potentiate and prolong the anti-nociceptive effects of opioids was tested. Forty-five men scheduled for aorto-coronary bypass operation received fentanyl according to their individual demands (haemodynamics, clinical parameters). The patients were allocated at random in...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Boldt J,von Bormann B,Kling D,Russ W,Ratthey K,Hempelmann G

    更新日期:1987-11-01 00:00:00

  • The use of dipyrone in the ICU is associated with acute kidney injury: A retrospective cohort analysis.

    abstract:BACKGROUND:Use of dipyrone (metamizole) in perioperative and ICU pain therapy remains controversial due to a lack of solid evidence weighing dipyrone benefit against its potential life-threatening complications. Although dipyrone has known analgesic and antipyretic properties, its mechanisms of actions are incompletely...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000627

    authors: Stueber T,Buessecker L,Leffler A,Gillmann HJ

    更新日期:2017-10-01 00:00:00

  • Comparison of the effects of mepivacaine and lidocaine on rat myocardium.

    abstract:BACKGROUND AND OBJECTIVE:To compare the inotropic and lusitropic effect of lidocaine and mepivacaine on rat papillary muscle. METHODS:Effects of lidocaine and mepivacaine (10-8-10-3 M) were studied in rat left ventricular papillary muscles in vitro at a calcium concentration of 1 mmol, under low (isotony) and high (is...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021506001359

    authors: David JS,Amour J,Duracher C,Ferretti C,Precloux P,Petit P,Riou B,Gueugniaud PY

    更新日期:2007-02-01 00:00:00

  • Maintenance of surgical muscle relaxation by repeat doses of vecuronium and atracurium at three different dose levels.

    abstract::The time-course of the neuromuscular effects of vecuronium (n = 25) and atracurium (n = 25) has been compared at three different levels of maintenance dose in anaesthetized patients. Following intubation with vecuronium 0.1 mg kg-1 or atracurium 0.5 mg kg-1, surgical muscle relaxation was maintained by using increment...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Khuenl-Brady KS,Scharz S,Richardson FJ,Mitterschiffthaler G

    更新日期:1991-01-01 00:00:00

  • High volume and low concentration of anaesthetic solution in the perivascular interscalene sheath determines quality of block and incidence of complications.

    abstract:BACKGROUND AND OBJECTIVE:In the perivascular sheath of the brachial plexus, the volume of anaesthetic solution determines the quality of anaesthetic cover. Fibrous septa may divide the perivascular space into compartments, leading to inadequate diffusion of the anaesthetic solution. The aim of our study was to obtain g...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021506001074

    authors: Pippa P,Cuomo P,Panchetti A,Scarchini M,Poggi G,D'Arienzo M

    更新日期:2006-10-01 00:00:00

  • Laparoscopically assisted vaginal and abdominal hysterectomy: comparison of postoperative pain, fatigue and systemic response. A case-control study.

    abstract:BACKGROUND AND OBJECTIVE:Laparoscopic and open surgery have been compared with conflicting results regarding their systemic responses. The sensitivity of biochemical markers that are used to discriminate between the stress responses to different types of surgery varies from study to study. We wanted to evaluate the str...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2346.2001.00889.x

    authors: Rorarius MG,Kujansuu E,Baer GA,Suominen P,Teisala K,Miettinen A,Ylitalo P,Laippala P

    更新日期:2001-08-01 00:00:00

  • Flurbiprofen does not change the bispectral index and 95% spectral edge frequency during total intravenous anaesthesia with propofol and fentanyl.

    abstract:BACKGROUND AND OBJECTIVE:Previous studies have shown that general anaesthetic agents modulate the production of hypothalamic prostaglandins (PG) D2 and E2, which are mediators of sleep and wakefulness respectively. Although flurbiprofen, a cyclo-oxygenase inhibitor, is used clinically as a non-steroidal anti-inflammato...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021502000790

    authors: Hirota K,Fukushi S,Baba S,Matsuki A

    更新日期:2002-07-01 00:00:00

  • A comparative study of patient-controlled epidural diamorphine, subcutaneous diamorphine and an epidural diamorphine/bupivacaine combination for postoperative pain.

    abstract::This randomized double blind study investigates the relative efficacies of controlled analgesia (PCA) regimens in three different patient groups: epidural diamorphine 2.5 mg followed by PCA bolus 1 mg with a 20-min lockout (Gp1), subcutaneous diamorphine 2.5 mg followed by PCA bolus with a 10-min lockout period (Gp2) ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2346.2000.00647.x

    authors: Gopinathan C,Sockalingham I,Fung MA,Peat S,Hanna MH

    更新日期:2000-03-01 00:00:00

  • Splanchnic perfusion during controlled hypotension with haemodilution under isoflurane anaesthesia in elderly patients.

    abstract::We investigated the effects of controlled hypotension with haemodilution under isoflurane anaesthesia on splanchnic perfusion in elderly patients. We determined the intramucosal pH using gastric tonometry in 28 patients scheduled for hip surgery. Patients without cardiac disease were assigned to two groups according t...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1365-2346.1999.00531.x

    authors: Fukusaki M,Nakamura T,Hara T,Fukushima H,Hasuo H,Sumikawa K

    更新日期:1999-08-01 00:00:00

  • Safety and efficacy of sugammadex for the reversal of rocuronium-induced neuromuscular blockade in cardiac patients undergoing noncardiac surgery.

    abstract:BACKGROUND AND OBJECTIVE:The present randomized, safety-assessor blinded, placebo-controlled trial was designed to assess safety and efficacy of sugammadex, a novel selective relaxant-binding agent, in patients with underlying cardiovascular disease undergoing noncardiac surgery. METHODS:Overall, 116 patients (New Yor...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/EJA.0b013e32832c605b

    authors: Dahl V,Pendeville PE,Hollmann MW,Heier T,Abels EA,Blobner M

    更新日期:2009-10-01 00:00:00

  • Duration of fluid fasting and choice of analgesic are modifiable factors for early postoperative delirium.

    abstract:BACKGROUND AND OBJECTIVE:Most therapeutic options for postoperative delirium are only symptom oriented; therefore, the best approach remains prevention. The aim of this study was to identify predisposing and precipitating factors for early postoperative delirium. METHODS:A total of 1002 patients were screened for deli...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0b013e3283335cee

    authors: Radtke FM,Franck M,MacGuill M,Seeling M,Lütz A,Westhoff S,Neumann U,Wernecke KD,Spies CD

    更新日期:2010-05-01 00:00:00

  • Implications of the use of neuromuscular transmission monitoring on immediate postoperative extubation in off-pump coronary artery bypass surgery.

    abstract:BACKGROUND AND OBJECTIVE:When continuous infusions of neuromuscular blocking drugs are administered during lengthy interventions and no routine antagonism of their effects is applied, there is a dramatic incidence of residual curarization. We have examined whether the use of neuromuscular transmission monitoring result...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s026502150300142x

    authors: Cammu G,De Keersmaecker K,Casselman F,Coddens J,Hendrickx J,Van Praet E,Deloof T

    更新日期:2003-11-01 00:00:00

  • Biphasic cardiac output changes during onset of spinal anaesthesia in elderly patients.

    abstract:BACKGROUND AND OBJECTIVE:In most studies of cardiac output changes after spinal anaesthesia, the time-resolution is limited. The aim of this study was to demonstrate cardiac output changes with high time-resolution during onset of spinal anaesthesia in elderly patients. METHODS:We investigated 32 patients aged 60 yr s...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021507000427

    authors: Meyhoff CS,Hesselbjerg L,Koscielniak-Nielsen Z,Rasmussen LS

    更新日期:2007-09-01 00:00:00

  • The influence of etomidate upon cerebral metabolites after complete brain ischaemia in the rat.

    abstract::The influence of etomidate on post-ischaemic cerebral metabolism was examined in 1-year-old male Wistar rats. Ten rats were randomly allocated to each of three groups. Group 1 animals received etomidate for 60 min without undergoing cerebral ischaemia. In Group 2, there was a 60-min recovery period following 15 min of...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:

    authors: Böhrer H,Hoyer S,Krier C

    更新日期:1991-05-01 00:00:00

  • Etomidate for critically ill patients. Con: do you really want to weaken the frail?

    abstract::Etomidate is an imidazole-derived hypnotic agent preferentially used for rapid sequence induction of anaesthesia because of its favourable haemodynamic profile. However, 11β-hydroxylase inhibition causes adrenal insufficiency with potentially fatal consequences in specific populations. We review the arguments against ...

    journal_title:European journal of anaesthesiology

    pub_type: 评论,杂志文章

    doi:10.1097/EJA.0b013e32835819ca

    authors: de la Grandville B,Arroyo D,Walder B

    更新日期:2012-11-01 00:00:00

  • Neostigmine-based reversal of intermediate acting neuromuscular blocking agents to prevent postoperative residual paralysis: A systematic review.

    abstract:BACKGROUND:Neostigmine is widely used to antagonise residual paralysis. Over the last decades, the benchmark of acceptable neuromuscular recovery has increased progressively to a train-of-four (TOF) ratio of at least 0.9. Raising this benchmark may impact on the efficacy of neostigmine. OBJECTIVE(S):The systematic rev...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000741

    authors: Tajaate N,Schreiber JU,Fuchs-Buder T,Jelting Y,Kranke P

    更新日期:2018-03-01 00:00:00

  • Dexmedetomidine and meperidine prevent postanaesthetic shivering.

    abstract:BACKGROUND AND OBJECTIVE:This placebo-controlled study was performed to evaluate the efficacy of dexmedetomidine compared with meperidine and placebo in preventing postanaesthetic shivering. METHODS:We studied 120 patients (ASA I-II) scheduled for elective abdominal or orthopaedic surgery of about 1-3 h duration. Fort...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021505002061

    authors: Bicer C,Esmaoglu A,Akin A,Boyaci A

    更新日期:2006-02-01 00:00:00

  • Acupressure at acupoint P6 for prevention of postoperative nausea and vomiting: a randomised clinical trial.

    abstract:BACKGROUND AND OBJECTIVE:Postoperative nausea and vomiting causes discomfort in many patients despite both antiemetic prophylactics and improved anaesthetic techniques. Stimulation of acupoint P6 is described as an alternative method for prophylaxis of postoperative nausea and vomiting.In a randomised, double-blinded s...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e32833f6f42

    authors: Majholm B,Møller AM

    更新日期:2011-06-01 00:00:00

  • The effect of dexmedetomidine sedation on brachial plexus block in patients with end-stage renal disease.

    abstract:BACKGROUND AND OBJECTIVE:The study investigated the effect of intravenous dexmedetomidine on brachial plexus block in patients with end-stage renal disease sedated with dexmedetomidine or midazolam for the formation of arteriovenous fistula. METHODS:A supraclavicular brachial plexus block was performed in 68 patients ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e32832a2244

    authors: Rutkowska K,Knapik P,Misiolek H

    更新日期:2009-10-01 00:00:00

  • Neurotoxicity with single dose intrathecal midazolam administration.

    abstract:BACKGROUND AND OBJECTIVE:The aim of study was to investigate the electron microscopic changes in the medulla of the spinal cord that occur with intrathecal midazolam administration. METHODS:Twenty-eight albino rabbits of New Zealand type were randomized into two groups. Following anaesthesia, 16 rabbits were given 300...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021505001547

    authors: Ugur B,Basaloglu K,Yurtseven T,Ates U,Aydin ON,Ozenç D,Yurtseven M,Gürel A

    更新日期:2005-12-01 00:00:00

  • Cognitive decline after carotid endarterectomy: Systematic review and meta-analysis.

    abstract:BACKGROUND:Postoperative cognitive decline (pCD) occurs frequently (6 to 30%) after carotid endarterectomy (CEA), although there are no exact estimates and risk factors are still unclear. OBJECTIVE:The objective of this study was to determine pCD incidence and risk factors in CEA patients. DESIGN:We performed a syste...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001130

    authors: Aceto P,Lai C,De Crescenzo F,Crea MA,Di Franco V,Pellicano GR,Perilli V,Lai S,Papanice D,Sollazzi L

    更新日期:2020-11-01 00:00:00

  • Drotrecogin alfa (activated): diffusion from clinical trials to clinical practice.

    abstract:BACKGROUND AND OBJECTIVE:Although the PROWESS trial demonstrated a mortality benefit, subsequent studies in different patient populations have not reproduced the effect. As a result, concerns have been expressed about the clinical effectiveness of drotrecogin alfa (activated). Therefore the aim of this audit was to rev...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021507002992

    authors: Ridley S,Lwin A,Wyncoll D,Lippett S,Watson D,Gunning K,Higgins D

    更新日期:2008-03-01 00:00:00

  • A case for competency-based anaesthesiology training with entrustable professional activities: an agenda for development and research.

    abstract::Competency frameworks are based on what are considered to be the general essential qualities of a doctor. Competencies, being behavioural descriptors, need a strong link to clinical practice to allow trainers to observe and then use them in assessing trainees' performance. The emerging concept of entrustable professio...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,评审

    doi:10.1097/EJA.0000000000000109

    authors: Jonker G,Hoff RG,Ten Cate OT

    更新日期:2015-02-01 00:00:00

  • Effect of injection speed on anaesthetic spread during axillary block using the orthogonal two-needle technique.

    abstract::One hundred patients undergoing scheduled upper limb orthopaedic surgery were studied to determine if the speed of injection of the local anaesthetic solution could modify the extent and depth of anaesthesia with the axillary approach to the brachial plexus. The blocks were performed using the 'orthogonal two-needle t...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rucci FS,Pippa P,Boccaccini A,Barbagli R

    更新日期:1995-09-01 00:00:00

  • Transverse vs. parasagittal in-plane approaches in ultrasound-guided paravertebral block using a microconvex probe: A randomised controlled trial.

    abstract:BACKGROUND:Several approaches have been proposed for ultrasound-guided thoracic paravertebral block, but the best approach remains unclear. OBJECTIVE:We compared two ultrasound-guided in-plane approaches using a microconvex probe, transverse and parasagittal. We assessed whether either approach would facilitate succes...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001223

    authors: Fujii T,Shibata Y,Shinya S,Nishiwaki K

    更新日期:2020-09-01 00:00:00

  • A comparison of two sedation techniques for neuroradiology.

    abstract::Two groups of 25 patients were sedated during neuroradiological investigation. The first group was sedated with fentanyl and midazolam while the other was given fentanyl and a two-stage infusion of propofol in a subanaesthetic dose. Both techniques resulted in satisfactory sedation and recovery, although those who rec...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Allan MW,Laurence AS,Gunawardena WJ

    更新日期:1989-09-01 00:00:00

  • The preventive effect of diphenhydramine on bacterial growth in propofol: a laboratory study.

    abstract:BACKGROUND AND OBJECTIVE:Diphenhydramine has local anaesthetic and antimicrobial activity and may be used to prevent intravenous propofol injection pain. We studied the effect of adding diphenhydramine to propofol emulsions for preventing bacterial growth. METHODS:Staphylococcus aureus, Pseudomonas aeruginosa, Escheri...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021508004377

    authors: Güzelant A,Apiliogullari S,Kara I,Turhan V,Apiliogullari B,Yilmaz H,Balasar M,Duman A

    更新日期:2008-09-01 00:00:00