Biphasic cardiac output changes during onset of spinal anaesthesia in elderly patients.

Abstract:

BACKGROUND AND OBJECTIVE:In most studies of cardiac output changes after spinal anaesthesia, the time-resolution is limited. The aim of this study was to demonstrate cardiac output changes with high time-resolution during onset of spinal anaesthesia in elderly patients. METHODS:We investigated 32 patients aged 60 yr scheduled for elective lower limb surgery. Fourteen received concurrent cardiovascular medication. Cardiac output was measured every 10 s using a pulse wave algorithm derived from the radial artery pressure curve, after calibration with lithium chloride (LiDCOplus). Data collection ended when the patients were ready for surgery, or if ephedrine was given to raise the mean arterial pressure. RESULTS:Cardiac output increased initially reaching a maximum after a mean of 7 min. The average increase was 1.1 L min(-1) (P<0.0001). This occurred when mean arterial pressure was reduced 14 mmHg on average. At the end of data collection, cardiac output decreased 0.5 L min(-1) from baseline (P=0.02). Mean arterial pressure decreased progressively in all patients, and only minimal changes in heart rate were found. CONCLUSIONS:Using this high time-resolution method, we detected biphasic changes in cardiac output during onset of spinal anaesthesia. Initially, cardiac output increased. Subsequently, it was significantly reduced from baseline, although this decrease was of minor clinical importance.

journal_name

Eur J Anaesthesiol

authors

Meyhoff CS,Hesselbjerg L,Koscielniak-Nielsen Z,Rasmussen LS

doi

10.1017/S0265021507000427

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

770-5

issue

9

eissn

0265-0215

issn

1365-2346

pii

S0265021507000427

journal_volume

24

pub_type

杂志文章
  • Effect of pre-operative oral carbohydrate loading on recovery after day-case cholecystectomy: A randomised controlled trial.

    abstract:BACKGROUND:Pre-operative carbohydrate loading has been shown to reduce pre-operative discomfort and postoperative nausea and vomiting in general surgical patients. Few studies have considered day-case surgery. OBJECTIVE:The aim of this prospective randomised study was to determine whether pre-operative carbohydrate lo...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000001002

    authors: Helminen H,Branders H,Ohtonen P,Saarnio J

    更新日期:2019-08-01 00:00:00

  • Preoperative oral dextromethorphan vs. clonidine to prevent tourniquet-induced cardiovascular responses in orthopaedic patients under general anaesthesia.

    abstract:BACKGROUND AND OBJECTIVE:Preoperative oral dextromethorphan and intravenous clonidine attenuate arterial pressure and heart rate increases during tourniquet inflation under general anaesthesia. The effect of preoperative oral clonidine on these variables has not been investigated. METHODS:We designed this study to com...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021506002055

    authors: Honarmand A,Safavi MR

    更新日期:2007-06-01 00:00:00

  • Remifentanil versus alfentanil in total intravenous anaesthesia for day case surgery.

    abstract:BACKGROUND AND OBJECTIVE:We assessed the intraoperative haemodynamic responses and recovery profiles of total intravenous anaesthesia with remifentanil and alfentanil for outpatient surgery. METHODS:Patients in Group 1 (n = 20) received alfentanil 20 microg kg(-1) followed by 2 microg kg(-1) min(-1) intravenously; pat...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021503000115

    authors: Alper I,Erhan E,Ugur G,Ozyar B

    更新日期:2003-01-01 00:00:00

  • Comparison of a continuous noninvasive arterial pressure device with invasive measurements in cardiovascular postsurgical intensive care patients: a prospective observational study.

    abstract:BACKGROUND:Arterial pressure monitoring using the a continuous noninvasive arterial pressure (CNAP) device during general anaesthesia is known to be interchangeable with continuous invasive arterial pressure (CIAP) monitoring. Agreement with invasive measurements in cardiovascular postsurgical intensive care patients h...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/EJA.0000000000000136

    authors: Ilies C,Grudev G,Hedderich J,Renner J,Steinfath M,Bein B,Haake N,Hanss R

    更新日期:2015-01-01 00:00:00

  • Maintenance of surgical muscle relaxation by repeat doses of vecuronium and atracurium at three different dose levels.

    abstract::The time-course of the neuromuscular effects of vecuronium (n = 25) and atracurium (n = 25) has been compared at three different levels of maintenance dose in anaesthetized patients. Following intubation with vecuronium 0.1 mg kg-1 or atracurium 0.5 mg kg-1, surgical muscle relaxation was maintained by using increment...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Khuenl-Brady KS,Scharz S,Richardson FJ,Mitterschiffthaler G

    更新日期:1991-01-01 00:00:00

  • Effect of glucose-insulin-potassium on hyperlactataemia in patients undergoing valvular heart surgery: A randomised controlled study.

    abstract:BACKGROUND:Hyperlactataemia represents oxygen imbalance in the tissues and its occurrence during cardiac surgery is associated with adverse outcomes. Glucose-insulin-potassium (GIK) infusion confers myocardial protection against ischaemia-reperfusion injury and has the potential to reduce lactate release while improvin...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000000250

    authors: Roh GU,Shim JK,Song JW,Kang HM,Kwak YL

    更新日期:2015-08-01 00:00:00

  • Comparison of laryngeal tube with laryngeal mask airway in anaesthetized and paralysed patients.

    abstract:BACKGROUND AND OBJECTIVE:The laryngeal mask has become a widely accepted alternative to endotracheal intubation and mask ventilation. The laryngeal tube is a relatively new supraglottic airway device for airway management. We compared the new version of the laryngeal tube with the laryngeal mask. METHODS:In a randomiz...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021507000129

    authors: Yildiz TS,Solak M,Toker K

    更新日期:2007-07-01 00:00:00

  • Comparison of rocuronium requirement in children with continuous infusion versus intermittent bolus: A randomised controlled trial.

    abstract:BACKGROUND:Minimising rocuronium administration during paediatric surgery helps to reduce the incidence of residual muscular blockade. OBJECTIVE:To determine whether intermittent bolus injection (Bolus group) or continuous infusion (group) requires the lesser amount of rocuronium. DESIGN:A randomised, single-blind co...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000000934

    authors: Choi SN,Jang YE,Lee JH,Kim EH,Kim JT,Kim HS

    更新日期:2019-03-01 00:00:00

  • Respiratory effects of the kneeling prone position for low back surgery.

    abstract:BACKGROUND AND OBJECTIVE:The kneeling prone position is often used for low back surgery in order to decrease intraoperative bleeding and increase the surgical exposure of the vertebral canal. The aim of this study was to assess effects of the kneeling prone position on respiratory gas exchange focusing on oxygen consum...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021504004053

    authors: Radstrom M,Loswick AC,Bengtsson JP

    更新日期:2004-04-01 00:00:00

  • Do muscle relaxants influence vascular tone in isolated coronary artery segments?

    abstract::The aim of this study was to elucidate the influence of four neuromuscular blocking substances on coronary vascular tone using the model of isolated porcine coronary artery segments. We studied the effects of four muscle relaxants, atracurium, pancuronium, rocuronium, and vecuronium (0.1, 1, and 10 microg mL-1 each), ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2346.2000.00712.x

    authors: Klockgether-Radke AP,Haemmerle A,Kettler D,Hellige G

    更新日期:2000-08-01 00:00:00

  • The postoperative analgesic efficacy of intraperitoneal tramadol compared to normal saline or intravenous tramadol in laparoscopic cholecystectomy.

    abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to compare the postoperative analgesic efficacy of intraperitoneal tramadol with intravenous tramadol or normal saline in patients undergoing laparoscopic cholecystectomy. METHODS:Sixty-one patients undergoing laparoscopic cholecystectomy were randomized to one of thr...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021508003694

    authors: Akinci SB,Ayhan B,Aycan IO,Tirnaksiz B,Basgul E,Abbasoglu O,Aypar U,Sayek I

    更新日期:2008-05-01 00:00:00

  • The orthogonal two-needle technique: a new axillary approach to the brachial plexus.

    abstract::Ninety-eight patients scheduled for elbow, forearm, wrist or hand surgery were allocated randomly to one of two different techniques of brachial plexus block, both using the axillary approach. The blocks were all performed at the level of the insertion of the lateral margin of the pectoralis major muscle on the humeru...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rucci FS,Boccaccini A,Doni L,Pippa P

    更新日期:1995-07-01 00:00:00

  • Repeat autoclaving does not remove protein deposits from the classic laryngeal mask airway.

    abstract:INTRODUCTION:We tested the hypothesis that repeated autoclaving removes protein deposits from the classic laryngeal mask airway (LMA). METHODS:Twenty previously used LMAs were hand washed, machine washed, dried, autoclaved and randomly allocated into four equal-sized groups for repeat autoclaving on 0 (control), 1, 2 ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021505000888

    authors: Bannon L,Brimacombe J,Nixon T,Keller C

    更新日期:2005-07-01 00:00:00

  • Nutrition support and treatment of motility disorders in critically ill patients - results of a survey on German intensive care units.

    abstract:BACKGROUND AND OBJECTIVE:To evaluate the current clinical attitude in enteral nutrition support and motility disorders in adult critically ill patients on German intensive care units. METHODS:A total of 1493 questionnaires, including 25 items on the medical environment, treatment of motility disorders and enteral nutr...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021507002657

    authors: Röhm KD,Schöllhorn T,Boldt J,Wolf M,Papsdorf M,Piper SN

    更新日期:2008-01-01 00:00:00

  • Epidural sufentanil for post-operative pain relief: effects of adrenaline.

    abstract::The analgesic, respiratory and haemodynamic effects of epidural sufentanil 75 micrograms (Group 1) or sufentanil 75 micrograms with adrenaline 75 micrograms (Group 2) were studied in 20 patients following abdominal surgery in a double-blind randomized trial. Pain relief, assessed on a linear analogue scale, sedation, ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Verborgh C,Van der Auwera D,Noorduin H,Camu F

    更新日期:1988-05-01 00:00:00

  • Combination of low doses of intrathecal ketamine and midazolam with bupivacaine improves postoperative analgesia in orthopaedic surgery.

    abstract:BACKGROUND:Intrathecal ketamine produces a short period of analgesia with stable haemodynamics. Midazolam with bupivacaine prolongs the duration of analgesia when administered intrathecally but does not prevent hypotension. The objective of this study was to assess the effect of a combination of intrathecal bupivacaine...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021507002645

    authors: Murali Krishna T,Panda NB,Batra YK,Rajeev S

    更新日期:2008-04-01 00:00:00

  • Pulse photoplethysmographic amplitude and heart rate variability during laparoscopic cholecystectomy: A prospective observational study.

    abstract:BACKGROUND:Surgical stress affects the autonomic nervous system by increasing sympathetic outflow. One method of monitoring sympathetic activity is pulse photoplethysmographic analysis. From this two indices can be derived - autonomic nervous system state (ANSS) and ANSS index (ANSSi). It has recently been claimed that...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000660

    authors: Colombo R,Raimondi F,Corona A,Marchi A,Borghi B,Pellegrin S,Bergomi P,Fossali T,Guzzetti S,Porta A

    更新日期:2017-08-01 00:00:00

  • A comparison of the effects of codeine and tramadol on laryngeal reactivity.

    abstract::The effect of tramadol on laryngeal reflex activity was assessed in a double-blind cross-over study in six volunteers receiving single oral doses of either codeine 50 mg, tramadol 50 mg or tramadol 100 mg. Laryngeal reactivity was measured by the response to the inhalation of dilute ammonia vapour. The minimum ammonia...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Szekely SM,Vickers MD

    更新日期:1992-03-01 00:00:00

  • The use of cuffed tracheal tubes for paediatric tracheal intubation, a survey of specialist practice in the United Kingdom.

    abstract:BACKGROUND AND OBJECTIVE:For more than 50 yr, uncuffed tracheal tubes have been the gold standard for intubation in children under the age of 8 yr. However, recently there has been interest in the use of cuffed tubes in paediatric practice. This survey aimed to benchmark UK practice with regard to tracheal intubation w...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021508003839

    authors: Flynn PE,Black AE,Mitchell V

    更新日期:2008-08-01 00:00:00

  • Genetics and postsurgical neuropathic pain: An ancillary study of a multicentre survey.

    abstract:BACKGROUND:Neuropathic pain following surgery could be a useful model for the study of the genetic mechanisms of peripheral neuropathic pain. OBJECTIVE:The aim of this study was to identify genetic predictors of persistent postsurgical neuropathic pain. DESIGN:An ancillary study from a prospective cohort. SETTING:Ei...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/EJA.0000000000000986

    authors: Blanc P,Génin E,Jesson B,Dubray C,Dualé C,EDONIS-gene Investigating group.

    更新日期:2019-05-01 00:00:00

  • The impact of continuous non-invasive arterial blood pressure monitoring on blood pressure stability during general anaesthesia in orthopaedic patients: A randomised trial.

    abstract:BACKGROUND:In patients undergoing general anaesthesia, intraoperative hypotension occurs frequently and is associated with adverse outcomes such as postoperative acute kidney failure, myocardial infarction or stroke. A history of chronic hypertension renders patients more susceptible to a decrease in blood pressure (BP...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000000690

    authors: Meidert AS,Nold JS,Hornung R,Paulus AC,Zwißler B,Czerner S

    更新日期:2017-11-01 00:00:00

  • The use of dipyrone in the ICU is associated with acute kidney injury: A retrospective cohort analysis.

    abstract:BACKGROUND:Use of dipyrone (metamizole) in perioperative and ICU pain therapy remains controversial due to a lack of solid evidence weighing dipyrone benefit against its potential life-threatening complications. Although dipyrone has known analgesic and antipyretic properties, its mechanisms of actions are incompletely...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000627

    authors: Stueber T,Buessecker L,Leffler A,Gillmann HJ

    更新日期:2017-10-01 00:00:00

  • Metabolic and subjective responses to oral diazepam and midazolam.

    abstract::Diazepam premedication decreases the overall metabolic rate and oxygen consumption. Whether its properties are shared by midazolam is not known. In this study, eight healthy male volunteers were given oral diazepam (10 mg), midazolam (15 mg) and placebo in a random double-blind cross-over fashion. Metabolic responses ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Kirvelä O,Katila A,Aantaa R,Kanto J,Himberg JJ

    更新日期:1994-09-01 00:00:00

  • Early experience with remote pressure sensor respiratory plethysmography monitoring sedation in the MR scanner.

    abstract:BACKGROUND AND OBJECTIVE:The importance of monitoring the breathing pattern during sedation of children undergoing magnetic resonance scans is indicated in guidelines, but no appropriate magnetic resonance-compatible devices are available. We report preliminary findings from a technique referred to as remote pressure s...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021507000312

    authors: Caldiroli D,Minati L

    更新日期:2007-09-01 00:00:00

  • Reducing the incidence of sore throat with the laryngeal mask airway.

    abstract::The incidence of sore throat after the use of the laryngeal mask was assessed with a randomized trial in 839 patients. Sore throat occurred more often in women, older patients or after multiple insertion attempts. It was found that the frequency in women, but not in men, was lowered from 11.9% to 3.9% (P = 0.012) by r...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Nott MR,Noble PD,Parmar M

    更新日期:1998-03-01 00:00:00

  • Duration of stabilization of control responses affects the onset and duration of action of rocuronium but not suxamethonium.

    abstract::The effect of the duration of stabilization of control responses on the onset and duration of clinical relaxation of suxamethonium 1 mg kg-1 and rocuronium 0.6 mg kg-1 were investigated in 90 patients. The control responses were allowed to stabilize for 1, 5, 10, 15 or 20 min prior to administration of rocuronium and ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2346.1996.d01-379.x

    authors: Symington MJ,McCoy EP,Mirakhur RK,Kumar N

    更新日期:1996-07-01 00:00:00

  • Patient-controlled epidural analgesia with morphine or morphine plus ketamine for post-operative pain relief.

    abstract::Sixty patients were randomly assigned to two equal groups. Group I received epidural morphine 1 mg after surgery and used a patient-controlled analgesia device programmed to deliver morphine 0. 2 mg h-1, 0.2 mg per bolus. Group II received an epidural loading dose of morphine 1 mg plus ketamine 5 mg and used a patient...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2346.1999.00592.x

    authors: Tan PH,Kuo MC,Kao PF,Chia YY,Liu K

    更新日期:1999-12-01 00:00:00

  • Mode of blood pressure monitoring and morbidity after noncardiac surgery: A prospective multicentre observational cohort study.

    abstract:BACKGROUND:Control of blood pressure remains a key goal of peri-operative care, because hypotension is associated with adverse outcomes after surgery. OBJECTIVES:We explored whether increased vigilance afforded by intra-arterial blood pressure monitoring may be associated with less morbidity after surgery. DESIGN:A p...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001443

    authors: Abbott TEF,Howell S,Pearse RM,Ackland GL,VISION-UK Investigators.

    更新日期:2021-01-12 00:00:00

  • The effects of sevoflurane, isoflurane and desflurane on QT interval of the ECG.

    abstract:BACKGROUND AND OBJECTIVE:To determine if there is any significant difference between the effects of desflurane, isoflurane and sevoflurane on the QT interval, QT dispersion, heart rate corrected QT interval and QTc dispersion of the electrocardiogram. METHODS:The study was conducted in a prospective, double blind and ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s0265021504007112

    authors: Yildirim H,Adanir T,Atay A,Katircioğlu K,Savaci S

    更新日期:2004-07-01 00:00:00

  • Bilateral phaeochromocytomas in pregnancy: anaesthetic management of combined caesarean section and tumour removal.

    abstract::A 25-year-old primigravida with bilateral phaeochromocytomas was managed from 6 weeks' gestation until 2.5 years following combined Caesarean section and removal of adrenal tumours. Pre-operative alpha-blockade was achieved by oral prazosin without deleterious effects. Intra-operative management comprised neuroleptana...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:

    authors: Pinaud M,Souron R,Le Neel JC,Lopes P,Murat A,L'hoste F

    更新日期:1985-12-01 00:00:00