Abstract:
:Two isomeric dimeric steroids, 3,3'-bis(methyl 3-hydroxyandrost-4-en-17-on-19-oate-3-yl), with symmetrical (alpha, alpha') and unsymmetrical structures (alpha,beta'), have been obtained by reduction of methyl androst-4-ene-3,17-dion-19-oate with zinc in aqueous acetic acid together with the major products, the isomeric methyl 5alpha- and 5beta-androst-3-en-17-on-19-oates. The structures of the dimers and unsaturated products are supported by spectroscopic methods. The symmetrical dimer was also obtained from treatment of the 4-en-3-on-19-oate ester with lithium in ammonia.
journal_name
Steroidsjournal_title
Steroidsauthors
Templeton JF,Majgier-Baranowska H,Marat Kdoi
10.1016/s0039-128x(99)00108-7subject
Has Abstractpub_date
2000-04-01 00:00:00pages
219-23issue
4eissn
0039-128Xissn
1878-5867pii
S0039-128X(99)00108-7journal_volume
65pub_type
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