Galactorrhoea and pituitary mass: a typical prolactinoma?

Abstract:

:A 21 year old woman presenting with galactorrhoea, hyperprolactinaemia, and a pituitary mass on magnetic resonance imaging (MRI) is described who was referred to us before planned pituitary surgery. Although a thorough history did not suggest hypothyroidism, laboratory studies revealed profound primary hypothyroidism. At that time, pituitary MRI showed homogeneous enlargement of the pituitary gland consistent with pituitary hyperplasia due to primary hypothyroidism. With thyroid hormone replacement therapy the galactorrhoea resolved, concentrations of prolactin and thyroid hormones returned to normal, and the pituitary shrunk to normal size within two months. This case illustrates that primary hypothyroidism can present only with galactorrhoea and pituitary mass, and should therefore be considered in the differential diagnosis of hyperprolactinaemia and pituitary enlargement.

journal_name

Postgrad Med J

authors

Brändle M,Schmid C

doi

10.1136/pmj.76.894.232

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

232-4

issue

894

eissn

0032-5473

issn

1469-0756

journal_volume

76

pub_type

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