Increased levels of GALbeta1-4GLCNACalpha2-6 sialyltransferase pretransplant predict delayed graft function in kidney transplant recipients.

abstract：BACKGROUND:The risk of transmitting a hepatitis B virus (HBV) infection from donor kidneys with a past HBV serological profile may be negligible. Data on HBV transmission to kidney transplant recipients from donor organs that were anti-HBc/HBsAg in Italy has not been previously reported. Anti-HBc testing in cadaver org...

journal_title：Transplantation

authors： De Feo TM,Grossi P,Poli F,Mozzi F,Messa P,Minetti E,Sandrini S,Boschiero L,Rigotti P,Maresca C,Rolla D,Chiaramonte S,Gotti E,Caldara R,Briano G,Scalamogna M

更新日期：2006-01-15 00:00:00

abstract：BACKGROUND:The long-term outcome of lung transplantation is impeded by the development of obliterative bronchiolitis (OB). We sought to investigate the relationship between the apoptosis of tracheal epithelial cells and bone marrow-derived myofibroblasts in the process of OB. METHODS:The mouse orthotopic tracheal tran...

journal_title：Transplantation

authors： Wang C,Xia T,Jiang K,Qiao X,Zhang X,Li J,Wang J,Nie J

更新日期：2016-09-01 00:00:00

abstract：:It has been postulated that the establishment of acquired, neonatal immunologic tolerance is due to a "deficit" in interleukin 2 (IL-2). To test this hypothesis, chickens were made immunologically tolerant to both major and minor histocompatibility antigens by transplantation of skin grafts onto newly hatched recipien...

journal_title：Transplantation

authors： Tempelis CH,Hála K,Krömer G,Schauenstein K,Wick G

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:The strategy of evaluating every donation opportunity warrants an investigation into the financial feasibility of this practice. The purpose of this investigation is to measure resource utilization required for procurement of transplantable organs in an organ procurement organization (OPO). METHODS:Donors w...

journal_title：Transplantation

authors： DuBay DA,Redden DT,Bryant MK,Dorn DP,Fouad MN,Gray SH,White JA,Locke JE,Meeks CB,Taylor GC,Kilgore ML,Eckhoff DE

更新日期：2014-05-27 00:00:00

abstract：:Islets were isolated from the pancreata of Sprague-Dawley rats and transplanted into streptozotocin-induced diabetic outbred Wistar rats. The effect of transplantation of islets into the cisterna magna on the diabetic state of the recipients was compared with that of the conventional transplantation of islets into liv...

journal_title：Transplantation

authors： Lee HC,Ahn KJ,Lim SK,Kim KR,Ahn YS,Lee KE,Huh KB

更新日期：1992-03-01 00:00:00

abstract：:The frequency of donor-reactive and of third party-reactive cytotoxic T lymphocyte precursors (CTLp) was determined by limiting dilution analysis in the peripheral blood of 13 liver allograft recipients before (pre-tpx) and at various intervals (4 to 22 months) after (post-tpx) transplantation. In 6 of 13 patients wit...

journal_title：Transplantation

authors： Eberspächer ML,Otto G,Herfarth C,Kabelitz D

更新日期：1994-06-27 00:00:00

abstract：:Although the cornea is considered to be an immunological privileged site, corneal transplantation can result in immunological rejection followed by graft failure, especially in patients with vascularized corneas. Several studies suggest a beneficial effect of matching for the HLA class I antigens on corneal graft surv...

journal_title：Transplantation

authors： Roelen DL,van Beelen E,van Bree SP,van Rood JJ,Völker-Dieben HJ,Claas FH

更新日期：1995-04-15 00:00:00

abstract：BACKGROUND:Brain death (BD) affects the viability of lungs for transplantation. A correlation exists between high lung inflammation after BD and the decrease in female sex hormones, especially estradiol. Therefore, we investigated the effects of 17β-estradiol (E2) treatment on the lungs of female brain dead rats. METH...

journal_title：Transplantation

authors： Ricardo-da-Silva FY,Armstrong R Jr,Vidal-Dos-Santos M,Correia CJ,Coutinho E Silva RDS,da Anunciação LF,Moreira LFP,Leuvenink HGD,Breithaupt-Faloppa AC

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:In a recent trial, targeted mild hypothermia in brain-dead organ donors significantly reduced the incidence of delayed graft function after kidney transplantation. This trial was stopped early for efficacy. Here, we report long-term graft survival for all organs along with donor critical care end points. ME...

journal_title：Transplantation

authors： Malinoski D,Patel MS,Axelrod DA,Broglio K,Lewis RJ,Groat T,Niemann CU

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Goal tacrolimus concentrations for the prevention of rejection in sensitized renal transplant recipients are not well established. METHODS:We evaluated the association between discharge tacrolimus trough concentration and the incidence of biopsy-proven acute rejection (BPAR) in 216 moderately sensitized ren...

journal_title：Transplantation

authors： Richards KR,Hager D,Muth B,Astor BC,Kaufman D,Djamali A

更新日期：2014-05-27 00:00:00

abstract：BACKGROUND:To determine the prevalence of GB virus-C/hepatitis G virus (GBV-C/HGV) infection in liver transplant recipients transplanted for non-hepatitis C virus indications, 44 patients transplanted for cryptogenic, autoimmune, hepatitis B, or cholestatic liver disease and 91 non-liver transplantation (LT) patients w...

journal_title：Transplantation

authors： Dickson RC,Qian KP,Lau JY

更新日期：1997-06-15 00:00:00

abstract：INTRODUCTION:This is a follow-up of a withdrawal study that we previously performed on 104 liver transplant patients in which immunosuppression was gradually withdrawn over a period of 3 years. Eighty-one patients were not able to be withdrawn (rejectors), and 23 patients were successfully weaned off immunosuppression ...

journal_title：Transplantation

authors： Tryphonopoulos P,Ruiz P,Weppler D,Nishida S,Levi DM,Moon J,Tekin A,Velez M,Neuman DR,Island E,Selvaggi G,Tzakis AG

更新日期：2010-12-27 00:00:00

abstract：BACKGROUND:Endomyocardial biopsy (EMB) remains the gold standard for acute cellular rejection (ACR) diagnosis in cardiac transplantation yet is subject to interobserver variability. A method that could avoid discordant EMB analysis would be desirable. The apoptosis rate in EMB correlates with ACR severity. Apollon inhi...

journal_title：Transplantation

authors： Aharinejad S,Andrukhova O,Gmeiner M,Thomas A,Krenn K,Zuckermann A,Grimm M

更新日期：2010-01-27 00:00:00

abstract：BACKGROUND:Intrapulmonary arteriovenous shunting (IPS), occasionally associated with advanced liver disease, may reverse after liver transplantation (LTx). Two-dimensional contrast-enhanced echocardiography, a convenient noninvasive study, has never been used to demonstrate disappearance of IPS after LTx. METHODS:For ...

journal_title：Transplantation

authors： Hasegawa T,Kamiyama M,Azuma T,Sasaki T,Okada A,Miwatani T,Matsushita T

更新日期：2000-02-27 00:00:00

abstract：:We examined graft and patient survival rates of 47,146 patients in the United Network for Organ Sharing registry following transplants between donors and recipients who were cytomegalovirus (CMV) antibody negative and positive. CMV positivity increased with age to about 80% in patients over 60. Seropositivity was seen...

journal_title：Transplantation

authors： Hirata M,Terasaki PI,Cho YW

更新日期：1996-07-15 00:00:00

abstract：:Although it has long been appreciated that establishment of chimerism is important in the acquisition and maintenance of allograft tolerance, the importance of this relationship has been reemphasized recently. Using the exquisite sensitivity of the polymerase chain reaction we have studied qualitatively and quantitati...

journal_title：Transplantation

authors： Alard P,Matriano JA,Socarras S,Ortega MA,Streilein JW

更新日期：1995-11-27 00:00:00

abstract：BACKGROUND:The deceased donor score (DDS), expanded criteria donor (ECD) definition, and resistive index (RI) were developed for pretransplant evaluation of donors. DDS and ECD are determined by a calculation of risk from donor variables, while RI is determined from flow characteristics of kidneys during machine preser...

journal_title：Transplantation

authors： Nyberg SL,Baskin-Bey ES,Kremers W,Prieto M,Henry ML,Stegall MD

更新日期：2005-10-15 00:00:00

abstract：BACKGROUND:Combined liver and kidney transplantation (CLKT) is a surgical challenge in small children because of technical aspects, lack of pediatric donors, and restrictions related to the size of the abdominal cavity. We report outcomes after CLKT in this challenging group of smaller children. METHOD:A review of pro...

journal_title：Transplantation

authors： Perera MT,Silva MA,Sharif K,McKiernan PJ,Kelly DA,Lloyd C,Milford DV,Mayer DA,Mirza DF

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND:Previous studies have identified more morbidity in simultaneous pancreas-kidney (SPK) transplant recipients compared with kidney alone (KA) recipients. With the development of novel immunosuppressive drugs, studies are needed to determine optimal treatment regimens in specific patient populations. METHODS:W...

journal_title：Transplantation

authors： Lee CM,Scandling JD,Krieger NR,Dafoe DC,Alfrey EJ

更新日期：1997-11-15 00:00:00

abstract：BACKGROUND:The use of calcineurin inhibitors is associated with chronic nephrotoxicity and lower glomerular filtration rate (GFR). As a result, one strategy of transplant immunosuppression is calcineurin inhibitor elimination. METHODS:The aim of this study was to determine the outcome of a prospective randomized trial...

journal_title：Transplantation

authors： Heilman RL,Younan K,Wadei HM,Mai ML,Reddy KS,Chakkera HA,Gonwa TA

更新日期：2011-10-15 00:00:00

abstract：:A 55-year-old woman underwent orthotopic liver transplantation for autoimmune chronic active hepatitis. Extensive portal and superior mesenteric venous thrombosis precluded standard portal venous reconstruction and necessitated use of a venous conduit from the recipient splenic vein of the donor liver. Flow through th...

journal_title：Transplantation

authors： Neelamekam TK,Geoghegan JG,Curry M,Hegarty JE,Traynor O,McEntee GP

更新日期：1997-04-15 00:00:00

abstract：:Limited recovery of contractile function and loss of coronary reactivity have been observed following prolonged hypothermic storage and transplantation of the heart. Since lipid peroxidation has a significant role in these deficits, we investigated the cardioprotective effects of a 21-aminosteroid. U74389G, 3 mg/kg i....

journal_title：Transplantation

authors： Duguay P,Chen H,Daloze P,Dumont L

更新日期：1996-04-15 00:00:00

abstract：:A retrospective masked study of 120 consecutive renal transplant biopsies was performed to evaluate the potential associations of cyclosporine (CsA) therapy and other factors on the degree and progression of interstitial fibrosis (IF). Allograft biopsies were obtained from patients receiving CsA (CsA+; n = 59) and not...

journal_title：Transplantation

authors： Ruiz P,Kolbeck PC,Scroggs MW,Sanfilippo F

更新日期：1988-01-01 00:00:00

abstract：:This study describes VG01, a monoclonal antibody to a novel lymphocyte activation antigen. The cells reacting with VG01 were first characterized by indirect immunofluorescence and fluorescence-activated cell sorter analysis. The antigen defined by VG01 was expressed on circulating T lymphocytes (23.8 +/- 9.0) and on t...

journal_title：Transplantation

authors： Denegri JF,Gilks CB,Altin M,Peterson J,Lafleur L

更新日期：1988-05-01 00:00:00

abstract：:Agarose is known to inhibit nonspecifically the cytotoxic effects of normal sera on xenogeneic lymphoid cells. To find an explanation for this agarose effect we have studied its requirements using guinea pig and human sera as the source of activity and rat thymocytes as target cells. Control assays were performed usin...

journal_title：Transplantation

authors： Budzko DB,Kierszenbaum F

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:Human intravenous immunoglobulin G delayed xenogeneic hyperacute rejection (HAR) in the guinea pig-to-rat combination. We investigated the respective roles of the Fc and Fab fragments of the IgG molecule in this inhibitory effect. METHODS:By using a guinea pig-to-rat heart transplantation model, the efficie...

journal_title：Transplantation

authors： Urbani L,Fabre M,Cardoso J,Lambin P,Devillier P,Soubrane O,Houssin D,Gautreau C

更新日期：1998-08-15 00:00:00

abstract：BACKGROUND:Patients with high tacrolimus clearance eliminate more drug within a dose interval compared with those with low clearance. Delays in dosing time will result in transient periods of lower concentrations in high versus low clearance patients. Transient subtherapeutic tacrolimus concentrations may induce acute ...

journal_title：Transplantation

authors： Egeland EJ,Robertsen I,Hermann M,Midtvedt K,Størset E,Gustavsen MT,Reisæter AV,Klaasen R,Bergan S,Holdaas H,Hartmann A,Åsberg A

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:To define whether immunosuppressive agents that block the interleukin (IL)-2 pathway could prevent activation-induced cell death of activated T cells in the graft, we measured expression of IL-2, IL-2 receptor alpha chain (CD25), IL-15, Fas, and Fas ligand by real time reverse transcription-polymerase chain ...

journal_title：Transplantation

authors： Baan CC,Balk AH,van Riemsdijk IC,Vantrimpont PJ,Maat AP,Niesters HG,Zondervan PE,van Gelder T,Weimar W

更新日期：2003-05-27 00:00:00

abstract：BACKGROUND:Bronchiolitis obliterans syndrome (BOS) is the leading cause of late mortality after lung transplantation. METHODS:We added azithromycin (AZI) (250 mg/day for 5 days, followed by 250 mg every other day) to the current immunosuppressive therapy in eight lung transplant recipients (mean age 36 years) with est...

journal_title：Transplantation

authors： Verleden GM,Dupont LJ

更新日期：2004-05-15 00:00:00

abstract：:Brainstem death is associated with endocrine and metabolic alterations that can result in donor hemodynamic instability. It has been suggested that these changes can be reversed through hormonal manipulation of the donor. We measured thyroid hormone levels (free triiodothyronine [fT3], free tetraiodothyronine [fT4], r...

journal_title：Transplantation

authors： Karayalçin K,Umaña JP,Harrison JD,Buckels JA,McMaster P,Mayer AD

更新日期：1994-03-15 00:00:00