Abstract:
:We employed a simple and relatively undemanding task of monotone counting for the assessment of sustained attention in schizophrenic patients. The monotone counting task has been validated neuropsychologically and is particularly sensitive to right prefrontal lesions. We compared the performance of schizophrenic patients with age- and education-matched controls. We then explored the extent to which a range of commonly employed neuropsychological tasks in schizophrenia research are related to attentional impairment as measured in this way. Monotone counting performance was found to be correlated with digit span (WAIS-R-HK), information (WAIS-R-HK), comprehension (WAIS-R-HK), logical memory (immediate recall) (Weschler Memory Scale, WMS), and visual reproduction (WMS). Multiple regression analysis also identified visual reproduction, digit span and comprehension as significant predictors of attention performance. In contrast, logical memory (delay recall) (WMS), similarity (WAIS-R-HK), semantic fluency, and Wisconsin Card Sorting Test (perseverative errors) were not correlated with attention. In addition, no significant correlation between sustained attention and symptoms was found. These findings are discussed in the context of a weakly modular cognitive system where attentional impairment may contribute selectively to a range of other cognitive deficits.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Chen EY,Lam LC,Chen RY,Nguyen DG,Chan CK,Wilkins AJdoi
10.1016/s0920-9964(96)00120-xsubject
Has Abstractpub_date
1997-04-11 00:00:00pages
299-310issue
3eissn
0920-9964issn
1573-2509pii
S092099649600120Xjournal_volume
24pub_type
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更新日期:2015-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0920-9964(01)00229-8
更新日期:2002-07-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/S0920-9964(97)00090-X
更新日期:1997-10-17 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2005.07.005
更新日期:2005-12-15 00:00:00
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doi:10.1016/j.schres.2010.03.033
更新日期:2010-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.schres.2006.01.022
更新日期:2006-06-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2004.02.008
更新日期:2005-03-01 00:00:00
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doi:10.1016/s0920-9964(01)00176-1
更新日期:2002-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.schres.2010.08.031
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更新日期:2009-12-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-02-01 00:00:00
abstract::Microtubule associated proteins (MAPs) are central to the development of normal neuronal cytoarchitecture and have been reported to be altered in schizophrenia. In 12 schizophrenic (DSM-III-R criteria) and 12 control hippocampi, we estimated the MAP2 immunoreactive dendritic length using antibodies that recognize tota...
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pub_type: 杂志文章
doi:10.1016/s0920-9964(99)00068-7
更新日期:2000-01-21 00:00:00
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pub_type: 杂志文章,meta分析
doi:10.1016/j.schres.2018.04.031
更新日期:2018-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.schres.2004.07.004
更新日期:2005-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-09-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.schres.2016.03.016
更新日期:2016-05-01 00:00:00