Functional anatomy of object recognition in humans: evidence from positron emission tomography and functional magnetic resonance imaging.

abstract：PURPOSE OF REVIEW:This review focuses on recent advances in the diagnostic approaches and the underlying pathophysiological mechanisms of Charcot-Marie-Tooth (CMT) disease. We also discuss the emerging therapies for this hereditary neuropathy. RECENT FINDINGS:To date, numerous genes are implicated in CMT, and new gene...

journal_title：Current opinion in neurology

authors： Vallat JM,Mathis S,Funalot B

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Cognitive impairments are common in children with epilepsy. They may already be present before the onset of epilepsy or occur - and even progress - during its course. Many variables contribute to cognitive dysfunction. Those that can be targeted to prevent (further) cognitive impairment will be highli...

journal_title：Current opinion in neurology

authors： Braun KP

更新日期：2017-04-01 00:00:00

abstract：:Disability following head injury varies depending on injury mechanism, neuropathology, and other factors, including medical complications. Mild head injury (Glasgow Coma Scale score 13-15) has been shown to have considerable variability in outcome. Some persons experience rapid symptom resolution whereas others contin...

journal_title：Current opinion in neurology

authors： Macciocchi SN,Reid DB,Barth JT

更新日期：1993-10-01 00:00:00

abstract：:Three genetic loci for Alzheimer's disease have been identified. These are the amyloid precursor gene on chromosome 21, a gene for early-onset autosomal dominant Alzheimer's disease on chromosome 14, and the risk-modifying gene APOE on chromosome 19. Additional Alzheimer's disease genes remain to be found. The genes i...

journal_title：Current opinion in neurology

authors： Schellenberg GD

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this study was to assess the seizure manifestations and risk of epilepsy in encephalitis associated with antibodies against neuronal cell-surface (autoimmune encephalitis) or myelin-associated antigens, and to review several chronic epileptic disorders, including Rasmussen's encephalitis, f...

journal_title：Current opinion in neurology

authors： Spatola M,Dalmau J

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Tension-type headache is the most common type of headache and, in its chronic form, one of the most neglected and difficult types of headache to treat. Recently published data will be reviewed. RECENT FINDINGS:The prevalence of frequent tension-type headache increased significantly from 1989 to 2001,...

journal_title：Current opinion in neurology

authors： Bendtsen L,Jensen R

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review on traumatic brain injury consolidates the substantial current literature available on the pathophysiology, mechanisms, developments, and their subsequent effects on outcome. In particular, it tries to conceptualize why our greatly improved understanding of pathophysiology and neurobiology...

journal_title：Current opinion in neurology

authors： Nortje J,Menon DK

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews what is known about the health and well being of adults with cerebral palsy. It also addresses the factors known to affect the areas identified in the World Health Organization International Classification of Functioning model as being critical for optimal health and well being. ...

journal_title：Current opinion in neurology

authors： Liptak GS

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Genetic discovery has been extremely rapid over the last year, with many new discoveries illuminating novel mechanisms and pathways. In particular, the application of whole exome and whole genome sequencing has identified many new genetic causes of the epilepsies. As such methods become increasingly a...

journal_title：Current opinion in neurology

authors： Sisodiya SM

更新日期：2015-04-01 00:00:00

abstract：:Since the first successful attempts in 1990, human embryonic tissue transplantation has attracted the attention of multiple investigators and clinicians as a serious candidate therapy for Parkinson's disease. Although over two hundred patients have undergone the procedure, multiple issues and questions remain unresolv...

journal_title：Current opinion in neurology

authors： Tabbal S,Fahn S,Frucht S

更新日期：1998-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The concept of epilepsy and seizure disorders caused by autoantibodies to specific neuronal membrane proteins has developed significantly during the past few years. RECENT FINDINGS:Antibodies to cell-surface membrane proteins such as voltage-gated potassium channels or N-methyl-D-aspartate receptors,...

journal_title：Current opinion in neurology

authors： Vincent A,Irani SR,Lang B

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the application of advanced MRI sequences such as magnetic resonance spectroscopy, diffusion tensor imaging and functional MRI for the evaluation of patients with altered consciousness. RECENT FINDINGS:Magnetic resonance spectroscopy, volumetry and diffusion tensor imaging have shown pro...

journal_title：Current opinion in neurology

authors： Galanaud D,Naccache L,Puybasset L

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The demyelinating disease multiple sclerosis has an autoimmune inflammatory component, which has dominated the description of multiple sclerosis. A degenerative component to multiple sclerosis was always apparent, but was underappreciated until recently. Recent work has brought axonal pathology and br...

journal_title：Current opinion in neurology

authors： Owens T

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the pathogenesis, clinical presentation, course, and therapy of herpes simplex encephalitis (HSE), the most fatal viral encephalitis, in which prognosis is dependent on early diagnosis and effective therapy. RECENT FINDINGS:Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) ...

journal_title：Current opinion in neurology

authors： Steiner I

更新日期：2011-06-01 00:00:00

abstract：:Stimulated by the impressive effect of interferon beta on magnetic resonance imaging-detected disease activity, the past year or so has seen a particular interest in the use of magnetic resonance imaging to monitor treatment. To be effective in this regard, there needs to be a high sensitivity and accuracy in detectin...

journal_title：Current opinion in neurology

authors： Miller DH

更新日期：1995-06-01 00:00:00

abstract：:This review centers on important recent advances in the understanding of the role of glial fibrillary acidic protein in Alexander disease and of proteolipid protein in hypomyelinating disorders such as Pelizaeus-Merzbacher and spastic paraplegia. We also describe seven novel leukodystrophies. These include childhood a...

journal_title：Current opinion in neurology

authors： Schiffmann R,Boespflüg-Tanguy O

更新日期：2001-12-01 00:00:00

abstract：:This is a review of chemotherapy options for patients with brain tumors, both at the time of initial diagnosis and at recurrence. Gliomas, the most common malignant brain tumors, represent the main focus of the review; chemotherapeutic options for supratentorial, brain stem, and optic track gliomas are discussed. ...

journal_title：Current opinion in neurology

authors： Galanis E,Buckner JC

更新日期：2000-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Malingered anterograde amnesia is a phenomenon that has been exhaustively studied, whereas research on retrograde amnesia has tended to focus upon functional and organic accounts of impairment. The present review explores studies relevant to extending the malingering paradigm to retrograde amnesia. R...

journal_title：Current opinion in neurology

authors： Jenkins KG,Kapur N,Kopelman MD

更新日期：2009-12-01 00:00:00

abstract：:A long series of studies beginning with the pioneering experiments of Wiesel and Hubel [1] has shown that correct visual experience is crucial for the development of the visual system. Recent results suggest that neurotrophic factors of the nerve growth factor family might have a relevant role in mediating the effects...

journal_title：Current opinion in neurology

authors： Pizzorusso T,Maffei L

更新日期：1996-04-01 00:00:00

abstract：:Desmin-related myopathies are marked by accumulation of desmin, which is often familial and associated with cardiomyopathy. When multifocal this excess is characterized by inclusions such as cytoplasmic or spheroid bodies, when disseminated the excess is called granulofilamentous material. Excess of desmin might repre...

journal_title：Current opinion in neurology

authors： Goebel HH

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Cervical spondylotic myelopathy (CSM) is a potentially debilitating disorder primarily related to spinal cord injury caused by degenerative changes of the spine. As the population continues to age and live longer, it is likely that this disorder will be encountered with increasing frequency. RECENT F...

journal_title：Current opinion in neurology

authors： Holly LT

更新日期：2009-12-01 00:00:00

abstract：:Recent findings from neuroimaging, event-related potential and lesion investigations reflect a rapidly emerging view that the memory system is widely distributed throughout the cortex. It is clear that the pattern of cortical involvement during encoding and retrieval of memories is critically dependent on the nature a...

journal_title：Current opinion in neurology

authors： Bright P,Kopelman MD

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Trigeminal autonomic cephalgias (TACs) are characterized by frequent, short-lasting headache attacks with ipsilateral facial autonomic features. They include cluster headache, paroxysmal hemicrania, and short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing. The...

journal_title：Current opinion in neurology

authors： Wilbrink LA,Ferrari MD,Kruit MC,Haan J

更新日期：2009-06-01 00:00:00

abstract：:In the past few years evidence that atherosclerotic disease of the aortic arch is probably an underestimate source of emboli, particularly moving thrombi in the lumen, has accumulated. Pathological studies, and more recently transesophageal echocardiographic studies, have shown that atherosclerotic disease of the aort...

journal_title：Current opinion in neurology

authors： Heinzlef O,Cohen A,Amarenco P

更新日期：1997-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The advent of novel techniques for tracing connections in vivo, such as diffusion tensor magnetic resonance imaging tractography, allows us, for the first time in the human brain, to study the microstructural integrity of white matter fibres and perform virtual dissections of large scale neurocognitiv...

journal_title：Current opinion in neurology

authors： Catani M

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Converging evidence from animal models of stroke and clinical trials suggests that aerobic exercise has effects across multiple targets. RECENT FINDINGS:The subacute phase is characterized by a period of heightened neuroplasticity when aerobic exercise has the potential to optimize recovery. In anima...

journal_title：Current opinion in neurology

authors： Ploughman M,Kelly LP

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Functional neuro-imaging studies of aphasic stroke offer the potential for a better understanding of the neuronal mechanisms that sustain language recovery. Conclusions, however, have been hampered by a set of unexpected challenges related to experimental design and interpretation. In this review of s...

journal_title：Current opinion in neurology

authors： Price CJ,Crinion J

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment response of brain tumours is typically evaluated with gadolinium-enhanced MRI using the Macdonald criteria. These criteria depend on changes in the area of enhancement. However, gadolinium enhancement of brain tumours primarily reflects impairment of the blood-brain barrier. RECENT FINDINGS...

journal_title：Current opinion in neurology

authors： Brandsma D,van den Bent MJ

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Tuberous sclerosis complex (TSC) is a multiorgan genetic disease caused by mutations in the TSC1 or TSC2 genes. TSC has been recognized for many years as an important cause of severe neurological disease with patients suffering from epilepsy, developmental delay, autism, and psychiatric problems. Duri...

journal_title：Current opinion in neurology

authors： Ess KC

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent advances in cochlear gene therapy over the past several years. Cochlear gene therapy has undergone tremendous advances over the past decade. Beginning with some groundbreaking work in 2005 documenting hair cell regeneration using virally mediated delivery of the mouse ato...

journal_title：Current opinion in neurology

authors： Lustig LR,Akil O

更新日期：2012-02-01 00:00:00