Plasticity in the developing visual system.

abstract：PURPOSE OF REVIEW:Emery-Dreifuss muscular dystrophy (EDMD) is caused by mutations in EMD encoding emerin and LMNA encoding A-type lamins, proteins of the nuclear envelope. In the past decade, there has been an extraordinary burst of research on the nuclear envelope. Discoveries resulting from this basic research have i...

journal_title：Current opinion in neurology

authors： Muchir A,Worman HJ

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There is an urgent need for effective therapies to restore neurologic function and decrease disability following traumatic brain injury (TBI). Here, emerging findings on the mechanisms of post-TBI neural repair and regeneration, as well as therapeutic implications, are selectively reviewed. RECENT FI...

journal_title：Current opinion in neurology

authors： Werner JK,Stevens RD

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to review sleep disturbances in different movement disorders, mainly Parkinson's disease, and highlight current concepts on merging the boundaries between movement disorders and dissociative states of being. RECENT FINDINGS:Since the observation that rapid eye movement sleep behavior disor...

journal_title：Current opinion in neurology

authors： Giannoccaro MP,Antelmi E,Plazzi G

更新日期：2013-08-01 00:00:00

abstract：:Deletion of the 1.5 Mb tract on chromosome 17p11.2-12 that is duplicated in Charcot-Marie-Tooth disease type 1A is commonly associated with hereditary neuropathy with liability to pressure palsies. The deletion, which originates from an unequal meiotic crossover involving two homologous repeats, causes underexpression...

journal_title：Current opinion in neurology

authors： Pareyson D,Taroni F

更新日期：1996-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Frontotemporal dementia (FTD) is a clinically, pathologically and genetically heterogeneous disorder. Mutations in a number of genes are associated with FTD, although until recently only two [progranulin (GRN) and microtubule-associated protein tau (MAPT)] were known to be major causes of the disease....

journal_title：Current opinion in neurology

authors： Rohrer JD,Warren JD

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The influence of anxiety on ocular motor control and gaze has received less research attention than its effects on postural control and locomotion. This review summarizes research on trait anxiety, state anxiety, anxiety disorders, ocular motor reflexes, and gaze. It applies these findings to clinical...

journal_title：Current opinion in neurology

authors： Staab JP

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Ten years of intensive research are now beginning to bring candidate neuroprotective therapies to clinical trials. This review describes recent progress in basic, preclinical, and clinical research that underlies current and potential neuroprotective trials. RECENT FINDINGS:Basic research continues t...

journal_title：Current opinion in neurology

authors： Hersch SM

更新日期：2003-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This article will review the recent experience with West Nile virus encephalitis and myelitis. RECENT FINDINGS:In the summer of 2003, the majority of cases of West Nile virus infection in the United States were reported from the western states. The transmission of West Nile virus through blood transf...

journal_title：Current opinion in neurology

authors： Roos KL

更新日期：2004-06-01 00:00:00

abstract：:This article reviews recent studies evaluating the clinicopathologic markers of progressive supranuclear palsy, which have helped establish standardized clinical and pathologic diagnostic criteria. Although these criteria increase diagnostic accuracy, the clinical and pathologic overlap between progressive supranuclea...

journal_title：Current opinion in neurology

authors： Litvan I

更新日期：1997-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic and often disabling neuropathy, which often responds to immune therapies including corticosteroids, plasma exchange, and high-dose intravenous immunoglobulin (IVIg). The reasons for choosing one of these therapies and the fa...

journal_title：Current opinion in neurology

authors： Nobile-Orazio E,Gallia F

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Stroke is the third leading cause of death after myocardial infarction and cancer, and is the leading cause of permanent disability and disability-adjusted loss of independent life-years in western countries. Thrombolysis is the treatment of choice for acute stroke within 3 h after the onset of sympto...

journal_title：Current opinion in neurology

authors： Schellinger PD,Kaste M,Hacke W

更新日期：2004-02-01 00:00:00

abstract：:We currently conceive of a migraine attack as originating in the brain. Triggers of an attack initiate a depolarizing neuroelectric and metabolic event likened to the spreading depression of Leao. This event activates the headache and associated features of the attack by mechanisms that remain to be determined, but ap...

journal_title：Current opinion in neurology

authors： Aurora SK,Welch KM

更新日期：2000-06-01 00:00:00

abstract：:New reports of the incidence, prevalence and mortality of Parkinson's disease and parkinsonism are reviewed. Evidence for occupational and lifestyle risk factors and protective factors is updated. Recent genetic epidemiology studies of parkinsonism in twins and families, and studies that investigated imaging and physi...

journal_title：Current opinion in neurology

authors： Tanner CM,Aston DA

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to review recent publications on amyotrophic lateral sclerosis (ALS). RECENT FINDINGS:The Awaji recommendations for electrophysiological diagnosis will permit earlier clinical trials entry. The use of ultrasound to visualize fasciculations, even in deep muscles, will contribute to earlier ...

journal_title：Current opinion in neurology

authors： de Carvalho M,Swash M

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the background, principles and implementation of the Stroke Action Plan for Europe 2018--2030 (SAP-E) in the perspective of the current COVID-19 pandemic. RECENT FINDINGS:SAP-E sets targets for the implementation of evidence-based preventive actions and stroke services to 2030. A recent m...

journal_title：Current opinion in neurology

authors： Christensen H,Pezzella FR,Action Plan for Stroke in Europe Implementation Steering Committee.

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To gain a complete understanding of how the brain functions, both in illness and good health, data from multiple levels of analysis must be integrated. Technical advances have made direct recordings of neuronal activity deep inside the human brain tractable, providing a rare glimpse into cellular proc...

journal_title：Current opinion in neurology

authors： Viskontas IV

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Gadolinium-enhancement depicts blood-brain barrier disruption associated with new inflammatory MRI lesions in multiple sclerosis (MS) and is widely used for diagnosis and therapeutic monitoring. However, earlier and more specific markers of inflammation are urgently needed. RECENT FINDINGS:Susceptibi...

journal_title：Current opinion in neurology

authors： Hagens M,van Berckel B,Barkhof F

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Inflammation is implicated in ischaemic stroke as a general cardiovascular risk factor, a possible immediate trigger, a component (and possible exacerbating factor) of the response to tissue injury, a marker of future risk, and as a therapeutic target. Each aspect is reviewed. RECENT FINDINGS:Evidenc...

journal_title：Current opinion in neurology

authors： Muir KW,Tyrrell P,Sattar N,Warburton E

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Cervical spondylotic myelopathy (CSM) is a potentially debilitating disorder primarily related to spinal cord injury caused by degenerative changes of the spine. As the population continues to age and live longer, it is likely that this disorder will be encountered with increasing frequency. RECENT F...

journal_title：Current opinion in neurology

authors： Holly LT

更新日期：2009-12-01 00:00:00

abstract：:The review intends to draw the attention of researchers working in retinal degenerations on the fact that classical apoptosis, for example, apoptosis triggering caspase activation, may not be the main pathway of cellular demise in this tissue.Former work already showed the difficulty of proving the activation of apopt...

journal_title：Current opinion in neurology

authors： Torriglia A,Jaadane I,Lebon C

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review presents the new terms and concepts proposed by the International League Against Epilepsy (ILAE) Classification Commission in 2010 to describe seizures and epilepsies. This is the first major revision in 21 years and reflects the rapid evolution in our understanding of the epilepsies. REC...

journal_title：Current opinion in neurology

authors： Korff CM,Scheffer IE

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Left visual neglect is a frequent and dramatic consequence of right hemisphere lesions. Diagnosis is important because behavioural and pharmacological treatments are available. Furthermore, neglect raises important issues concerning the brain mechanisms of consciousness, perception and attention. REC...

journal_title：Current opinion in neurology

authors： Bartolomeo P

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the most relevant developments in the understanding of headache in idiopathic intracranial hypertension (IIH). RECENT FINDINGS:The phenotype of the typical IIH headache is diverging from the historical thinking of a raised intracranial pressure headache, with the majority being classified a...

journal_title：Current opinion in neurology

authors： Mollan SP,Hoffmann J,Sinclair AJ

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Here we summarize the evidence from human studies of the impairments to the structural, functional, and metabolic capacities in skeletal muscle in those with type 1 diabetes (T1D) - a condition known as diabetic myopathy. Given the importance of skeletal muscle for blood lipid and glucose management, ...

journal_title：Current opinion in neurology

authors： Monaco CMF,Perry CGR,Hawke TJ

更新日期：2017-10-01 00:00:00

abstract：:The population of pediatric patients with cerebrovascular disease presents a unique set of challenges to the neurosurgeon. The wide scope of pathology, including arteriovenous malformations, cavernous malformations and moyamoya disease, coupled with marked advances in diagnosis and treatment of these conditions over t...

journal_title：Current opinion in neurology

authors： Smith ER,Butler WE,Ogilvy CS

更新日期：2002-04-01 00:00:00

abstract：:Disability following head injury varies depending on injury mechanism, neuropathology, and other factors, including medical complications. Mild head injury (Glasgow Coma Scale score 13-15) has been shown to have considerable variability in outcome. Some persons experience rapid symptom resolution whereas others contin...

journal_title：Current opinion in neurology

authors： Macciocchi SN,Reid DB,Barth JT

更新日期：1993-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The funduscopic examination can be a technically difficult, and often omitted, portion of the neurologic examination, despite its great potential to influence patient care. RECENT FINDINGS:Medical practitioners are often first taught to examine the ocular fundus using a direct ophthalmoscope, however...

journal_title：Current opinion in neurology

authors： Rodenbeck SJ,Mackay DD

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Preterm infants are at high risk for neurological sequelae and cognitive dysfunction. These problems have been attributed to a high occurrence of central nervous system (CNS) lesions, but suboptimal brain development appears to be just as important. In this brief review we present the hypothesis that ...

journal_title：Current opinion in neurology

authors： Hagberg H,Mallard C

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Our current treatment algorithms include only IFN-β and glatiramer as available first-line disease-modifying drugs and natalizumab and fingolimod as second-line therapies. Today, 10 drugs have been approved in Europe and nine in the United States making the choice of therapy more complex. The purpose ...

journal_title：Current opinion in neurology

authors： Sorensen PS

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the extensive research carried out in the past decades, the current pathophysiological notions of neurodegenerative disease as well as effective treatments to reduce their progression are largely unknown. Alterations of the human microbiota, the plethora of different microscopic organisms that...

journal_title：Current opinion in neurology

authors： Marizzoni M,Provasi S,Cattaneo A,Frisoni GB

更新日期：2017-12-01 00:00:00