Advances in the understanding of headache in idiopathic intracranial hypertension.

abstract：PURPOSE OF REVIEW:Left visual neglect is a frequent and dramatic consequence of right hemisphere lesions. Diagnosis is important because behavioural and pharmacological treatments are available. Furthermore, neglect raises important issues concerning the brain mechanisms of consciousness, perception and attention. REC...

journal_title：Current opinion in neurology

authors： Bartolomeo P

更新日期：2007-08-01 00:00:00

abstract：:This is a review of chemotherapy options for patients with brain tumors, both at the time of initial diagnosis and at recurrence. Gliomas, the most common malignant brain tumors, represent the main focus of the review; chemotherapeutic options for supratentorial, brain stem, and optic track gliomas are discussed. ...

journal_title：Current opinion in neurology

authors： Galanis E,Buckner JC

更新日期：2000-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Tension-type headache is the most common type of headache and, in its chronic form, one of the most neglected and difficult types of headache to treat. Recently published data will be reviewed. RECENT FINDINGS:The prevalence of frequent tension-type headache increased significantly from 1989 to 2001,...

journal_title：Current opinion in neurology

authors： Bendtsen L,Jensen R

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Neuroimaging in motor neuron disease (MND) has traditionally been seen as an academic tool with limited direct relevance to individualized patient care. This has changed radically in recent years as computational imaging has emerged as a viable clinical tool with true biomarker potential. This transit...

journal_title：Current opinion in neurology

authors： Bede P,Querin G,Pradat PF

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This article will highlight recent advances in dystonia with focus on clinical aspects such as the new classification, syndromic approach, new gene discoveries and genotype-phenotype correlations. Broadening of phenotype of some of the previously described hereditary dystonias and environmental risk f...

journal_title：Current opinion in neurology

authors： Balint B,Bhatia KP

更新日期：2014-08-01 00:00:00

abstract：:Dermatomyositis and polymyositis are treatable disorders of skeletal muscle. Despite their clinical similarities, they appear to have fundamentally different autoimmune origins. Inclusion body myositis, from its origins 30 years ago, has emerged as the commonest acquired myopathy of the elderly. Despite inflammatory c...

journal_title：Current opinion in neurology

authors： Hilton-Jones D

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Frontotemporal dementia (FTD) is a clinically, pathologically and genetically heterogeneous disorder. Mutations in a number of genes are associated with FTD, although until recently only two [progranulin (GRN) and microtubule-associated protein tau (MAPT)] were known to be major causes of the disease....

journal_title：Current opinion in neurology

authors： Rohrer JD,Warren JD

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The cause of multiple sclerosis remains elusive. We review recent epidemiological studies of genetic and environmental factors that influence susceptibility to the disease and its clinical course. RECENT FINDINGS:Genetic advances strengthen the association of multiple sclerosis with the human leukocy...

journal_title：Current opinion in neurology

authors： Kantarci O,Wingerchuk D

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews what is known about the health and well being of adults with cerebral palsy. It also addresses the factors known to affect the areas identified in the World Health Organization International Classification of Functioning model as being critical for optimal health and well being. ...

journal_title：Current opinion in neurology

authors： Liptak GS

更新日期：2008-04-01 00:00:00

abstract：:At the dawning of the present decade, deemed appropriately the Decade of the Spine, acute spinal cord injury lingers as a formidable disorder affecting society. The enormous physical, emotional and socioeconomic impact of acute spinal cord injury on society is well known. Consequently, intensive clinical and laborator...

journal_title：Current opinion in neurology

authors： Dumont AS,Dumont RJ,Oskouian RJ

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Small vessel diseases of the brain are still clinically underrecognized whereas their burden is increasing steeply. The most frequent is acquired degenerative small vessel disease. Many hereditary or idiopathic small vessel diseases have also been identified, of which cerebral autosomal-dominant arter...

journal_title：Current opinion in neurology

authors： Ringelstein EB,Nabavi DG

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with asymptomatic carotid stenosis are at increased vascular risk but optimal treatment is controversial. We reviewed the current evidence for medical and surgical intervention in these patients. RECENT FINDINGS:Optimal medical treatment is the most important aspect of management of patients...

journal_title：Current opinion in neurology

authors： Redgrave JN,Rothwell PM

更新日期：2007-02-01 00:00:00

abstract：:Slowly, advances are being made in the understanding and treatment of primary childhood brain tumors. The addition of chemotherapy has resulted in better survival for children with medulloblastoma. For other tumor types, therapeutic advances have been slower. High-dose chemotherapy is increasingly being employed to tr...

journal_title：Current opinion in neurology

authors： Packer RJ

更新日期：1997-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to refer to recent arguments supporting the existence of specific propagation mechanisms associated with spreading of neuron injury in amyotrophic lateral sclerosis (ALS). RECENT FINDINGS:Misfolded ALS-linked protein accumulation can induce aggregation of their native equiva...

journal_title：Current opinion in neurology

authors： Pradat PF,Kabashi E,Desnuelle C

更新日期：2015-10-01 00:00:00

abstract：:In multifocal motor or sensorimotor neuropathy with persistent conduction block, most of the recent research has concerned treatment. Open trials show that intravenous immunoglobulin is effective, providing a rapid and often marked clinical improvement, accompanied by a significant reduction of conduction block in som...

journal_title：Current opinion in neurology

authors： Léger JM

更新日期：1995-10-01 00:00:00

abstract：:Mild cognitive impairment is not an established diagnosis but a concept for which different criteria have been proposed and modified over time. Mild cognitive impairment refers to the transitional zone between normal ageing and dementia. The mild cognitive impairment stage may be one of the optimum stages at which to ...

journal_title：Current opinion in neurology

authors： Voisin T,Touchon J,Vellas B

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Only two functionally validated susceptibility genes, CACNA1H and GABRD, have so far been identified in the common epilepsies using a candidate gene approach. The difficulty with the alternative statistical approach, where none of the suggested candidates has been functionally validated, may partly be...

journal_title：Current opinion in neurology

authors： Tan NC,Mulley JC,Scheffer IE

更新日期：2006-04-01 00:00:00

abstract：:Primary germ-cell tumors of the central nervous system are rare neoplasms that are seen primarily in the pediatric age group. Because of their frequent location in the pituitary and suprasellar regions, they present with typical neuro-ophthalmologic and neuroendocrine symptoms. Sophisticated imaging and surgical biops...

journal_title：Current opinion in neurology

authors： Hooda BS,Finlay JL

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The diagnosis of amyotrophic lateral sclerosis (ALS) still relies mainly on clinical criteria. In present review we will provide an overview of neurochemical ALS biomarkers, which are in the most advanced position on the way towards inclusion into the clinical work-up. RECENT FINDINGS:The field of AL...

journal_title：Current opinion in neurology

authors： Verde F,Silani V,Otto M

更新日期：2019-10-01 00:00:00

abstract：:This paper reviews clinical reports of various movement disorders (dystonia, chorea, ballism and parkinsonism) caused by well defined lesions of the putamen, globus pallidus, substantia nigra, thalamus and subthalamus. The role of basal ganglia in motor control is also emphasized. ...

journal_title：Current opinion in neurology

authors： Berardelli A

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize advances in our understanding of the clinical phenotypes, genetics, and molecular pathophysiology of the periodic paralyses, the nondystrophic myotonias, and other muscle channelopathies. RECENT FINDINGS:The number of pathogenic mutations causing periodic paralysis, nondystrophic myotoni...

journal_title：Current opinion in neurology

authors： Platt D,Griggs R

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The results of phase 2 randomized controlled trials for the prevention of episodic and chronic migraine demonstrating the efficacy and safety of four mAbs targeting the calcitonin gene-related peptide (CGRP) pathway [ALD403 (eptinezumab), AMG334 (erenumab), LY2951742 (galcanezumab) and TEV48125 (frema...

journal_title：Current opinion in neurology

authors： Mitsikostas DD,Reuter U

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The trigeminal autonomic reflex is a physiological reflex with an important protective function which also plays a role in pathophysiological conditions, such as primary headache. It is not understood whether the autonomic symptoms in trigeminal autonomic cephalalgias and migraine are the consequence ...

journal_title：Current opinion in neurology

authors： Möller M,May A

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Stroke thrombolysis is in the process of moving from academic centers into community-based standard therapy in experienced centers. Recently published data on patient selection, imaging and other technical or organizational advances are reviewed in order to improve the safety and efficacy of stroke th...

journal_title：Current opinion in neurology

authors： Lindsberg PJ,Kaste M

更新日期：2003-02-01 00:00:00

abstract：:The motoneuron has a strong ability to regenerate after injury. However, the problems of nerve cell survival after a proximal axotomy, difficulty in axonal elongation after intraspinal lesion and the lack of target specificity during nerve fibre regrowth interfere with a good functional restitution. Current research h...

journal_title：Current opinion in neurology

authors： Carlstedt T

更新日期：2000-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The 2016 WHO classification of tumors of the central nervous system (2016 CNS WHO) features many changes that are relevant to neurologists treating patients with brain tumors as well as neurologists involved in basic, clinical, and epidemiological research. This review summarizes what neurologists nee...

journal_title：Current opinion in neurology

authors： DeWitt JC,Mock A,Louis DN

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Severe childhood traumatic brain injury (TBI) is the leading cause of death and acquired disability in children, causing impairments in children's sensory-motor, cognitive and behavioural functioning, with devastating consequences on community integration. Community integration is the ultimate goal of...

journal_title：Current opinion in neurology

authors： Chevignard MP,Brooks N,Truelle JL

更新日期：2010-12-01 00:00:00

abstract：:Neural circuits comprised of dopamine-containing and dopamine-receptive neurons are altered functionally after the repeated intermittent administration of cocaine and its withdrawal. The characterization of these neuroadaptive changes at various times after repeated exposure to cocaine is important because they may re...

journal_title：Current opinion in neurology

authors： Pilotte NS

更新日期：1997-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review on traumatic brain injury consolidates the substantial current literature available on the pathophysiology, mechanisms, developments, and their subsequent effects on outcome. In particular, it tries to conceptualize why our greatly improved understanding of pathophysiology and neurobiology...

journal_title：Current opinion in neurology

authors： Nortje J,Menon DK

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The demyelinating disease multiple sclerosis has an autoimmune inflammatory component, which has dominated the description of multiple sclerosis. A degenerative component to multiple sclerosis was always apparent, but was underappreciated until recently. Recent work has brought axonal pathology and br...

journal_title：Current opinion in neurology

authors： Owens T

更新日期：2003-06-01 00:00:00