Effect of in vitro aging on Campylobacter rectus lipopolysaccharide-stimulated PGE2 release from human gingival fibroblasts.

Abstract:

OBJECTIVE:We examined the influence of in vitro aging on Campylobacter rectus (C. rectus) lipopolysaccharide (LPS)-stimulated prostaglandin (PG), E2 release frOm human gingival fibroblasts (HGFs). MATERIALS AND METHODS:LPS was prepared from C. rectus ATCC33238. HGFs were established from healing gingival tissue removed from three patients (donors A, B and C), aged 10-12 years. Aging of the cells in culture was determined with increasing population doubling. The cells were cultured until confluence, then stimulated with LPS (1.0 micrograms ml-1), and the levels of PGE2 in the medium were measured after 24 h by radioimmunoassay. RESULTS:The LPS-stimulated PGE2 production in each old cell (passage 17-20) was significantly increased to about 1.6-2.6 times than that in the corresponding young cells (passage 5-6). The gene expression of cyclooxygenase-2 mRNA in the old cells was higher than that in the young cells in response to LPS. In the absence of LPS, PGE2 production levels in both the young and old cells were very low, and also at the same level. However, there was a higher level of LPS-stimulated PGE2 production in the young cells from donor C compared to that in the old cells from donor B. The LPS-stimulated PGE2 production in each young cell from donors A and C was almost equal to that in each old cell from donors B and A, respectively. CONCLUSIONS:The results suggested that aging in HGFs may be one of the factors that take part in the stimulation of C. rectus LPS-stimulated PGE2 production in old cells.

journal_name

Oral Dis

journal_title

Oral diseases

authors

Takiguchi H,Yamaguchi M,Mochizuki K,Abiko Y

doi

10.1111/j.1601-0825.1996.tb00225.x

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

202-9

issue

3

eissn

1354-523X

issn

1601-0825

journal_volume

2

pub_type

杂志文章
  • Cigarette smoking, alcohol drinking, and oral and pharyngeal cancer mortality in Japan.

    abstract:OBJECTIVES:To prospectively examine the association of cigarette smoking and alcohol drinking with oral and pharyngeal carcinogenesis, we analyzed data from a nation-wide large-scale cohort study in Japan. METHODS:A total of 34 136 men and 43 711 women aged 40-79 years were included in the study. The Cox proportional ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2007.01378.x

    authors: Ide R,Mizoue T,Fujino Y,Hoshiyama Y,Sakata K,Tamakoshi A,Yoshimura T,JACC Study Group.

    更新日期:2008-05-01 00:00:00

  • The impact of age on oral squamous cell carcinoma: A longitudinal cohort study of 2,782 patients.

    abstract:BACKGROUND:The purposes of this study were to assess the influence of age on oral squamous cell carcinoma patients and sought to analyze the reasons that may contribute to this difference. METHODS:This study enrolled 2,782 patients included 2,443 patients in a retrospective cohort to find the influence of age and 339 ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13015

    authors: Xu Q,Wang C,Li B,Kim K,Li J,Mao M,Qin L,Li H,Huang X,Xing R,Han Z,Feng Z

    更新日期:2019-04-01 00:00:00

  • Osteomyelitis, osteoradionecrosis, or medication-related osteonecrosis of the jaws? Can CBCT enhance radiographic diagnosis?

    abstract:OBJECTIVE:To attempt defining differential radiographic diagnostic characteristics for osteonecrotic lesions using 2D as opposed to 3D images. MATERIALS AND METHODS:This was a cross-sectional study. Subjects presenting mandibular osteonecrotic lesions (osteomyelitis, osteoradionecrosis, and medication-related osteonec...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13534

    authors: Gaêta-Araujo H,Vanderhaeghen O,Vasconcelos KF,Coucke W,Coropciuc R,Politis C,Jacobs R

    更新日期:2021-03-01 00:00:00

  • Periodontitis in patients with psoriasis: A systematic review and meta-analysis.

    abstract:OBJECTIVE:The present study aimed to summarize and update the evidence regarding the association between periodontitis and psoriasis. METHODS:The present systematic review was conducted under the guidelines of Transparent Reporting of Systematic Reviews and Meta-Analyses (PRISMA) and was recorded in the PROSPERO datab...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.13617

    authors: Zhang X,Gu H,Xie S,Su Y

    更新日期:2020-08-27 00:00:00

  • Occupational COVID-19 risk to dental staff working in a public dental unit in the outbreak epicenter.

    abstract:OBJECTIVE:The management of the COVID-19 outbreak occurred in Lombardy (Italy) implied that non-COVID-19 health care was remodeled, limiting adequate resources in non-hospital public dental healthcare settings. This situation offered the opportunity to investigate the occupational COVID-19 risk to dental staff in publi...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13632

    authors: Nardone M,Cordone A,Petti S

    更新日期:2020-09-03 00:00:00

  • Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands.

    abstract:OBJECTIVES:Salivary glands are useful target organs for local and systemic gene therapeutics. For such applications, the regulation of transgene expression is important. Previous studies by us in murine submandibular glands showed that a rapamycin transcriptional regulation system in a single serotype 2, adeno-associat...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2009.01631.x

    authors: Zheng C,Voutetakis A,Metzger M,Afione S,Cotrim AP,Eckhaus MA,Rivera VM,Clackson T,Chiorini JA,Donahue RE,Dunbar CE,Baum BJ

    更新日期:2010-04-01 00:00:00

  • The oral health status of dentate patients with chronic renal failure undergoing dialysis therapy.

    abstract:OBJECTIVE:The aim of this study was to compare the oral health status of chronic renal failure (CRF) patients on renal replacement therapy with a matched reference population. DESIGN:Cross-sectional study. SUBJECTS:Forty-two dentate CRF patients--aged 25-52 years old--were matched with a reference group of 808 dentat...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2005.01183.x

    authors: Bots CP,Poorterman JH,Brand HS,Kalsbeek H,van Amerongen BM,Veerman EC,Nieuw Amerongen AV

    更新日期:2006-03-01 00:00:00

  • Panoramic radiography measurements, osteoporosis diagnoses and fractures in Japanese men and women.

    abstract:OBJECTIVES:The purpose of this study was to investigate the association of the shape of the mandibular cortex on panoramic radiographs with the risk of an osteoporosis diagnosis without prevalent fractures and with the risk of osteoporotic fractures in Japanese men and women. SUBJECTS AND METHODS:One thousand and twen...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12282

    authors: Yamada S,Uchida K,Iwamoto Y,Sugino N,Yoshinari N,Kagami H,Taguchi A

    更新日期:2015-04-01 00:00:00

  • GLUT-1 in oral benign vascular lesions.

    abstract:AIM:To investigate the accuracy of histological diagnosis of oral hemangioma, oral vascular malformation and oral pyogenic granuloma according to immunohistochemical evaluation of the human erythrocyte-type glucose transporter protein (GLUT-1), and to observe the immunoexpression of this protein in oral varix. MATERIA...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2006.01246.x

    authors: Johann AC,Salla JT,Gomez RS,de Aguiar MC,Gontijo B,Mesquita RA

    更新日期:2007-01-01 00:00:00

  • MicroRNA-21 promotes orthodontic tooth movement by modulating the RANKL/OPG balance in T cells.

    abstract:OBJECTIVES:The present study was designed to investigate the effects of microRNA-21 (miR-21) on orthodontic tooth movement. METHODS:The orthodontic tooth movement model was established in C57BL/6 and miR-21-/- mice with or without implantation of activated T cells. Histological and histomorphometrical analyses were pe...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13239

    authors: Wu L,Su Y,Lin F,Zhu S,Wang J,Hou Y,Du J,Liu Y,Guo L

    更新日期:2020-03-01 00:00:00

  • HIV infection and periodontal diseases: an overview of the post-HAART era.

    abstract::HIV infection remains a global health problem of unprecedented dimensions, although the development of highly active antiretroviral therapy (HAART) has significantly modified the course of HIV disease into a manageable chronic disease with longer survival and improved quality of life in HIV-infected subjects. Among th...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2010.01727.x

    authors: Mataftsi M,Skoura L,Sakellari D

    更新日期:2011-01-01 00:00:00

  • Pathogenesis investigation of miR-199-5p in oral submucous fibrosis based on bioinformatics analysis.

    abstract:OBJECTIVES:Fibrosis diseases are one of the leading causes of suffering and death. However, no systematic investigation has been carried out on fibrosis-related genes. MATERIALS AND METHODS:By querying PubMed using keywords "fibrosis" and "gene" or "protein," we identified fibrosis-related genes in the last decade. Bi...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13008

    authors: Yuan Y,Li N,Zeng L,Shen Z,Jiang C

    更新日期:2019-03-01 00:00:00

  • Salivary protein candidates for biomarkers of oral disorders in alcohol and tobacco dependents.

    abstract:OBJECTIVES:To evaluate the oral condition of alcohol and tobacco dependents and identify salivary protein candidates for biomarkers of oral disorders. SUBJECTS AND METHODS:Thirty-three male volunteers were evaluated for alcohol abuse rehabilitation; nine were selected for proteomic analysis. Intraoral examination was ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13337

    authors: Penteado CAS,Batista TBD,Chaiben CL,Bonacin BG,Ventura TMO,Dionizio A,Couto Souza PH,Buzalaf MAR,Azevedo-Alanis LR

    更新日期:2020-04-01 00:00:00

  • Poland-Moebius syndrome: a case with oral anomalies.

    abstract::The combination of Moebius and Poland anomalies is rarely described in the literature. While some authors believe this association is an independent syndrome, others think that Poland, Moebius and Poland-Moebius syndromes are variations of the same condition. We report a case of Poland-Moebius syndrome in a 6-year-old...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2004.01045.x

    authors: Domingos AC,Lopes SL,Almeida SM,Boscolo FN,Whaites EJ

    更新日期:2004-11-01 00:00:00

  • Submandibular gland excision: From external surgery to robotic intraoral and extraoral approaches.

    abstract::Submandibular gland excision is generally performed through a transcervical approach, a safe procedure that, however, carries few neurological, functional and aesthetic drawbacks. Intraoral approach to the submandibular gland has been described many years ago but it has been newly proposed in recent years thanks to en...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13340

    authors: Cammaroto G,Vicini C,Montevecchi F,Bonsembiante A,Meccariello G,Bresciani L,Pelucchi S,Capaccio P

    更新日期:2020-07-01 00:00:00

  • A multicenter study of oral sarcomas in Brazil.

    abstract:OBJECTIVES:The aim of this study was to investigate the prevalence of oral sarcomas from geographic regions of Brazil. MATERIALS AND METHODS:A cross-sectional study was conducted on biopsies obtained from January 2007 to December 2016 at twelve Brazilian oral and maxillofacial pathology centres. Gender, age, evolution...

    journal_title:Oral diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/odi.13211

    authors: de Carvalho WRS,de Souza LL,Pontes FSC,Uchôa DCC,Corrêa DL,de Cáceres CVBL,Lopes MA,Santos-Silva AR,Vargas PA,de Andrade BAB,Romañach M,Gomez RS,Costa SFDS,Batista AC,Mendonça EF,Pinto DDS Júnior,Gondak R,da Cruz Perez

    更新日期:2020-01-01 00:00:00

  • Secretory leukocyte protease inhibitor (SLPI) in mucosal fluids inhibits HIV-I.

    abstract::Despite the presence of HIV-1 in the oral cavity, transmission of the virus through saliva has not been proven. Consistent with these observations, we recently identified an endogenous 12 kD protein, secretory leukocyte protease inhibitor (SLPI), in saliva which blocks HIV-1 infection in vitro. Whereas other salivary ...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.1997.tb00377.x

    authors: Wahl SM,McNeely TB,Janoff EN,Shugars D,Worley P,Tucker C,Orenstein JM

    更新日期:1997-05-01 00:00:00

  • Borate bioactive glass prevents zoledronate-induced osteonecrosis of the jaw by restoring osteogenesis and angiogenesis.

    abstract:OBJECTIVES:Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe complication of systemic nitrogen-containing bisphosphonate (N-BP) administration, which leads to osteonecrosis, pain, and infection. Despite much effort, effective remedies are yet to be established. This study aimed to investigate potentia...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13436

    authors: Su Z,Li J,Bai X,Tay FR,Zhang M,Liang K,He L,Yuan H,Li J

    更新日期:2020-11-01 00:00:00

  • Hyaline ring granuloma of the mouth-A foreign-body reaction that dentists should be aware of: Critical review of literature and histochemical/immunohistochemical study of a new case.

    abstract::Hyaline ring granuloma (HRG) is a rare and atypical foreign-body granulomatous chronic inflammatory condition. Our aim was to make a critical review of the literature cases and also to illustrate histochemical and immunohistochemical findings of a new case. A modified PICO strategy was used. Inclusion criteria were me...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.13287

    authors: Kimura TC,Carneiro MC,Coelho YFS,de Sousa SCOM,Veltrini VC

    更新日期:2020-01-24 00:00:00

  • Dysplastic oral leukoplakia is molecularly distinct from leukoplakia without dysplasia.

    abstract:OBJECTIVE:The molecular mechanisms underlying the development of dysplasia in leukoplakia are unknown. We used RNA sequencing to examine the molecular and biological pathway differences in oral leukoplakia with and without oral epithelial dysplasia. MATERIALS AND METHODS:Excisional biopsy specimens (25) were taken fro...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13156

    authors: Farah CS,Fox SA

    更新日期:2019-10-01 00:00:00

  • Effect of aluminum concentration on dental caries formation in the rat.

    abstract:OBJECTIVE:Topically applied aluminum (AI) reduced fissure caries in rats with indigenous microflora, but neither therapeutic activity nor concentration effects have been studied in animals infected with caries-inducing bacteria. This study investigated the effects of solutions containing various AI concentrations on fo...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.1995.tb00164.x

    authors: Putt MS,Kleber CJ

    更新日期:1995-06-01 00:00:00

  • Salivary secretion, mucin concentrations and Candida carriage in HIV-infected patients.

    abstract:OBJECTIVES:To test whether the submandibular/sublingual (SMSL) salivary secretion, mucin concentration and candida carriage status were altered in human immunodeficiency virus-positive (HIV+) patients. SUBJECTS AND METHODS:SMSL saliva collected from 48 HIV-infected and 31 HIV-negative men were analyzed for flow rates,...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2009.01514.x

    authors: Jainkittivong A,Lin AL,Johnson DA,Langlais RP,Yeh CK

    更新日期:2009-04-01 00:00:00

  • Survivin expression in odontogenic keratocysts and correlation with cytomegalovirus infection.

    abstract:OBJECTIVES:The aim of this study was to investigate the expression of survivin, an inhibitor of apoptosis, in odontogenic keratocysts and to compare it to the findings in non-neoplastic jaw cysts - periapical cysts, as well as to establish a possible relationship between survivin expression and human cytomegalovirus pr...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2009.01612.x

    authors: Andric M,Dozic B,Popovic B,Stefanovic D,Basta-Jovanovic G,Djogo N,Andjus P,Milasin J

    更新日期:2010-03-01 00:00:00

  • Priming response to inflammatory mediators in hyperreactive peripheral neutrophils from adult periodontitis.

    abstract:OBJECTIVES:To study the response to in vitro priming of peripheral neutrophils from patients with periodontitis compared to healthy controls. Peripheral neutrophils from these patients had shown increased production of oxygen radicals after activation with opsonized bacteria and a difference in priming response could s...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.1997.tb00030.x

    authors: Gustafsson A,Asman B,Bergström K

    更新日期:1997-09-01 00:00:00

  • Mucoepidermoid carcinoma of minor salivary glands: a clinical study of 16 cases and review of the literature.

    abstract:OBJECTIVE:Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of salivary glands with a widely diverse biologic behavior that is correlated with the histological grade of the tumor. The purpose of this study was to evaluate the clinical outcomes of MEC of minor salivary glands in a group of 16 patients, w...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2005.01166.x

    authors: Triantafillidou K,Dimitrakopoulos J,Iordanidis F,Koufogiannis D

    更新日期:2006-07-01 00:00:00

  • Traditional Chinese medicine and oral diseases: today and tomorrow.

    abstract::With a history of over 2000 years, traditional Chinese medicine (TCM) evolves into a unique system of diagnosing and treating illnesses. It is a challenge to convey the fundamentals of this traditional medicine to our Western colleagues because of the differences in language, philosophy and concept of diagnosis and tr...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2010.01706.x

    authors: Zheng LW,Hua H,Cheung LK

    更新日期:2011-01-01 00:00:00

  • Intra-oral carcinomas in Maiduguri, north-eastern Nigeria.

    abstract:OBJECTIVE:To document the pattern of intra-oral carcinomas diagnosed in north-eastern Nigeria. DESIGN AND SETTING:A retrospective clinical and histopathological review seen in a tertiary care hospital (January 1987-December 2002). MATERIALS AND METHODS:Information on socio-demographic characteristics of patients and ...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2005.01134.x

    authors: Otoh EC,Johnson NW,Olasoji HO,Danfillo IS,Adeleke OA

    更新日期:2005-11-01 00:00:00

  • Clinical, microbiological and ultrastructural features of angular cheilitis lesions in Southern Chinese.

    abstract:OBJECTIVE:To obtain baseline data on angular cheilitis in Southern Chinese. DESIGN:A cross-sectional investigation of the clinical, microbiological and ultrastructural features of the condition. SUBJECTS AND METHOD:Thirty six Chinese adults with angular cheilitis; 28 controls matched for age and sex, with no inflamma...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.1995.tb00156.x

    authors: Dias AP,Samaranayake LP

    更新日期:1995-03-01 00:00:00

  • Oral potentially malignant disorders: A consensus report from an international seminar on nomenclature and classification, convened by the WHO Collaborating Centre for Oral Cancer.

    abstract::Oral potentially malignant disorders (OPMDs) are associated with an increased risk of occurrence of cancers of the lip or oral cavity. This paper presents an updated report on the nomenclature and the classification of OPMDs, based predominantly on their clinical features, following discussions by an expert group at a...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.13704

    authors: Warnakulasuriya S,Kujan O,Aguirre-Urizar JM,Bagan JV,González-Moles MÁ,Kerr AR,Lodi G,Mello FW,Monteiro L,Ogden GR,Sloan P,Johnson NW

    更新日期:2020-10-31 00:00:00

  • Oral disease in the elderly in long-term hospital care.

    abstract:OBJECTIVE:To obtain baseline information on the prevalence of oral problems and disease in institutionalized elderly in a Scottish hospital. DESIGN:A cross-sectional clinical investigation with complementary microbiological studies as appropriate. SUBJECTS AND METHODS:A cohort of 147 elderly in five long-term care wa...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.1995.tb00177.x

    authors: Samaranayake LP,Wilkieson CA,Lamey PJ,MacFarlane TW

    更新日期:1995-09-01 00:00:00