Is Chlamydia pneumoniae present in brain lesions of patients with multiple sclerosis?

Abstract:

:We investigated the presence of Chlamydia pneumoniae in 81 normal and pathological specimens obtained from postmortem brain tissues of patients with multiple sclerosis and with other neurological or nonneurological diseases. The assays used included PCR amplification of all DNA samples in the initial study. Culture and a second PCR amplification of the organism in a subset of 19 brain specimens were also performed in two separate laboratories. All results were negative. Thus, this study on a large number of brain tissues suggests that C. pneumoniae is not involved in inflammatory demyelination.

journal_name

J Clin Microbiol

authors

Hammerschlag MR,Ke Z,Lu F,Roblin P,Boman J,Kalman B

doi

10.1128/JCM.38.11.4274-4276.2000

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

4274-6

issue

11

eissn

0095-1137

issn

1098-660X

journal_volume

38

pub_type

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