Changes of expression level of the differentiation markers in papillary thyroid carcinoma under thyrotropin suppression therapy in vivo immunohistochemical detection of thyroglobulin, thyroid peroxidase, and thyrotropin receptor.

Abstract:

BACKGROUND AND OBJECTIVES:Differences in the expression levels of Thyroglobulin (Tg), Thyroid peroxidase (TPO) and thyrotropin receptor (TSH-R) in primary and recurrent specimens under a suppressive serum TSH condition were elucidated in 26 papillary carcinoma patients. METHODS:Immunohistochemical detection was performed by use of each monoclonal antibody against Tg, TPO, and TSH-R. The staining concentrations of the three markers in each specimen were measured for comparison. RESULTS:The mean staining concentrations of Tg, TPO, and TSH-R in the entire primary tumor were 103.92, 104.6 and 89.25, respectively. Five cases showed stronger expression of all the differentiation markers and eight cases showed weaker expression of all these markers in recurrent tissue than in primary tumors. The weaker expression of TSH-R at the recurrent site as compared with that at the primary site significantly demonstrated the shortness of the disease free interval or overall survival. There were significant differences between the death due to cancer and the weaker expression of TSH-R in the recurrent tumor as compared with that in the primary tumor. CONCLUSIONS:Under the TSH suppressive condition, the markers were not expressed uniformly among recurrent tumors. Even under that state, however, low expression of TSH-R in the recurrent tissue was strongly related to a poorer outcome in the patients.

journal_name

J Surg Oncol

authors

Tanaka K,Sonoo H,Yamamoto Y,Udagawa K,Kunisue H,Arime I,Yamamoto S,Kurebayashi J,Shimozuma K

doi

10.1002/1096-9098(200010)75:2<108::aid-jso7>3.0.co

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

108-16

issue

2

eissn

0022-4790

issn

1096-9098

pii

10.1002/1096-9098(200010)75:2<108::AID-JSO7>3.0.CO

journal_volume

75

pub_type

杂志文章
  • Prediction of microvascular invasion before curative resection of hepatocellular carcinoma.

    abstract:BACKGROUND:The accurate staging of hepatocellular carcinoma (HCC) is important in establishing treatment strategies and prognosis. Among tumor factors, microvascular invasion, one of TNM staging components and prognostic factors, is underestimated preoperatively, due to inaccuracy of imaging modalities. We investigated...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20953

    authors: Kim BK,Han KH,Park YN,Park MS,Kim KS,Choi JS,Moon BS,Chon CY,Moon YM,Ahn SH

    更新日期:2008-03-01 00:00:00

  • Impact of specific modes of circumferential resection margin involvement in rectal cancer local recurrence: A retrospective study.

    abstract:PURPOSE:To compare the local recurrence rate and overall survival between patients with circumferential resection margin (CRM) involvement by direct tumor spread and by a tumor within a lymph node. METHODS:A total of 776 patients diagnosed with rectal cancer underwent rectal resection. Patients with CRM involvement by...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25252

    authors: Suárez J,Goicoetxea A,Gómez ML,Jiménez G,Llanos MC,Jiménez J,Montes B,de Miguel M

    更新日期:2018-12-01 00:00:00

  • Safety of rectum anastomosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

    abstract:BACKGROUND AND OBJECTIVES:In highly selected patients with peritoneal carcinomatosis, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) can be an aggressive but worthwhile treatment regimen. Resection of the rectosigmoid is frequently performed with CRS. The aim of the study wa...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25189

    authors: von Breitenbuch P,Piso P,Schlitt HJ

    更新日期:2018-09-01 00:00:00

  • Autologous flap breast reconstruction: Surgical algorithm and patient selection.

    abstract::Whole breast reconstruction using autologous tissue is the gold standard in many regions of the world. Reasons include breast replacement with native skin and fat, ability to shape and mold the tissue into a breast, no foreign materials are necessary, and it lasts forever when successful. There are now many options fo...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.24208

    authors: Nahabedian MY,Patel K

    更新日期:2016-06-01 00:00:00

  • Detubularized rectosigmoid neobladder in women after cystectomy for bladder cancer.

    abstract:BACKGROUND AND OBJECTIVES:We present the long-term functional results of a new technique for bladder substitution after cystectomy for bladder cancer in women. METHODS:Between 1991 and 1995, 10 women underwent radical cystectomy for bladder cancer with a new technique. We created a detubularized rectosigmoid neobladde...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200005)74:1<49::aid-jso12>3.0.co

    authors: Mearini E,Mearini L,Zucchi A,Costantini E,Goracci G,Porena M

    更新日期:2000-05-01 00:00:00

  • New intraoperative brachytherapy techniques for positive or close surgical margins.

    abstract::Tumors attached or adjacent to critical structures can often not be completely resected or resected with adequate surgical margins. Sites involving major blood vessels, the paravertebral spaces, or critical abdominal structures often present technical difficulties for standard brachytherapy procedures using I-125 or I...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930420112

    authors: Nori D,Bains M,Hilaris BS,Harrison L,Fass D,Peretz T,Donath D,Fuks Z

    更新日期:1989-09-01 00:00:00

  • Abnormal expression of miR-301a in gastric cancer associated with progression and poor prognosis.

    abstract:BACKGROUND AND OBJECTIVES:miR-301a is significantly overexpressed in many cancers. However, its expression and biological role in gastric cancer remain poorly understood. We investigated microRNA-301a (miR-301a) expression in gastric cancer and determined its effects on cancer cell behavior and its clinical significanc...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23374

    authors: Xu XD,He XJ,Tao HQ,Zhang W,Wang YY,Ye ZY,Zhao ZS

    更新日期:2013-09-01 00:00:00

  • Merkel tumor of the lower lip: a case report and updated review of the literature work performed at the University of Illinois.

    abstract::An unusual case of Merkel cell carcinoma of the lower lip with metastasis to the submental nodes is presented. Clinical similarities and the histopathologic and prognostic differences between this tumor and basal or squamous cell carcinomas of the head and neck area are discussed and the current thoughts for treatment...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930370212

    authors: Dolezal RF,Cohen M,Taxy JB

    更新日期:1988-02-01 00:00:00

  • Non-neurogenic soft tissue tumours of the axilla: prospective review of 16 cases.

    abstract::Sixteen consecutive patients entered in a prospective study of non-neurogenic soft tissue tumours had lesions in the axilla. Delayed diagnosis and inappropriate biopsy prior to referral to a surgical oncologist were frequent findings. Sarcoma and fibromatosis were diagnosed in 14 cases, and the approaches used for the...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930420203

    authors: Bell RS,Ready J,Hudson A,O'Sullivan B,Mahoney J,Richards R,Davis A,Fornasier VL

    更新日期:1989-10-01 00:00:00

  • Expression of intercellular adhesion molecule-1 in hepatocellular carcinoma.

    abstract::The expression of intercellular adhesion molecule-1 (ICAM-1) was investigated in frozen sections obtained from 40 resected liver specimens of patients with hepatocellular carcinoma using immunoperoxidase techniques and immunoelectron microscopy. ICAM-1 was expressed in 80% of the HCC specimens on the membrane of cance...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930530410

    authors: Torii A,Harada A,Nakao A,Nonami T,Ito M,Takagi H

    更新日期:1993-08-01 00:00:00

  • Reconstruction of the hypopharynx with the free jejunum transfer.

    abstract::Microsurgical techniques have revolutionized pharyngolaryngeal reconstruction. Free flap reconstruction with the free jejunal flap enables one stage reconstruction with minimal morbidity and mortality. This review will examine indications, operative technique, postoperative management, and expected outcomes for the hy...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.20483

    authors: Disa JJ,Pusic AL,Mehrara BJ

    更新日期:2006-11-01 00:00:00

  • ABO (H) cell surface antigens in benign and malignant parotid neoplasms.

    abstract::Twenty-two inflammatory, benign, or malignant parotid lesions were studied by means of the specific red cell adherence test (SRCA), a modification of the Coombs' mixed cell agglutination reaction. In 22 normal parotid tissues the acinar structures were devoid of red cell agglutination, but it was present in ductal epi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930240306

    authors: Woltering EA,Tuttle SE,James AG,Sharma HM

    更新日期:1983-11-01 00:00:00

  • Untreated colorectal cancer in a community hospital.

    abstract::The tumor registry of a community hospital has been reviewed, and 60 patients with untreated colon and rectal cancer have been identified. Thirty-four patients were black and 26 patients were white. Sixty-five percent of black patients had specified colonic lesions primarily distributed in the right colon and proximal...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930290314

    authors: Johnson H Jr

    更新日期:1985-07-01 00:00:00

  • Health-related quality of life and treatment modality among esophageal squamous cell carcinoma survivors: A prospective study using time to deterioration model analysis.

    abstract:BACKGROUND AND OBJECTIVES:This study aimed to analyze the association between health-related quality of life and treatment modality among esophageal squamous cell carcinoma (ESCC) survivors. METHODS:Patients completed the EORTC QLQ-C30 and EORTC QLQ-OES18 at baseline and follow-up. A time to deterioration model analys...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.26264

    authors: Liu S,Lin Z,Lin J,Chen H,Xie Q,Rao W,Chen Y,Yu K,Hu Z

    更新日期:2021-01-01 00:00:00

  • Large segment allograft survival is improved with intramedullary cement.

    abstract:BACKGROUND AND OBJECTIVES:The most common cause of failure in large segment bone allografts used for oncologic reconstruction is allograft fracture. Reinforcement with pressurized intramedullary cement may improve the mechanical properties of allografts. METHODS:We reviewed the prospectively collected records of 45 pa...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.10316

    authors: Gerrand CH,Griffin AM,Davis AM,Gross AE,Bell RS,Wunder JS

    更新日期:2003-12-01 00:00:00

  • Long-term outcomes in treatment of retroperitoneal sarcomas: A 15 year single-institution evaluation of prognostic features.

    abstract:BACKGROUND:Retroperitoneal sarcomas are connective tissue tumors arising in the retroperitoneum. Surgical resection is the mainstay of treatment. Debate has arisen over extent of resection, changes in histological classification/grading, and interest in incorporating radiotherapy. Therefore, we reviewed our institution...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24256

    authors: Abdelfatah E,Guzzetta AA,Nagarajan N,Wolfgang CL,Pawlik TM,Choti MA,Schulick R,Montgomery EA,Meyer C,Thornton K,Herman J,Terezakis S,Frassica D,Ahuja N

    更新日期:2016-07-01 00:00:00

  • Granular cell tumor: a clinicopathologic study of 110 patients.

    abstract::The clinicopathologic features of 118 granular cell tumors (GCT) encountered at two affiliated hospitals were reviewed. A total of 110 patients were affected over this 32-year period of study (71 men, 39 women), and in 5% GCT were multiple. Patients ranged in age from 16 to 58 years (average 32 years) and were symptom...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930130405

    authors: Lack EE,Worsham GF,Callihan MD,Crawford BE,Klappenbach S,Rowden G,Chun B

    更新日期:1980-01-01 00:00:00

  • Needle aspiration cytologic diagnosis of metastatic malignant melanoma of unknown primary origin: report of a case and review of the literature.

    abstract::A rare case of metastatic malignant melanoma of unknown primary origin in a 49-year-old woman is reported. The swelling, localized in the right inguinal region, was partially immovable and associated with progressively increasing pain. Initial diagnosis was set by needle aspiration cytology and was confirmed postopera...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.2930350409

    authors: Eftichiadou C,Vartholomeos A,Salem N,Destouni E,Apostolidis P

    更新日期:1987-08-01 00:00:00

  • Staging invasive bladder tumors.

    abstract::Staging of bladder tumors is based primarily on the depth of tumor invasion (T-category). Stage is important to treatment planning and prognosis. The problem is that clinical evaluation by T-category alone often understages the pathologic extent of disease and does not reliably predict treatment results. The current a...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.2930510403

    authors: Herr HW

    更新日期:1992-12-01 00:00:00

  • Growth inhibition of intracerebral rat glioma by transfection-induced human interferon-beta.

    abstract::In our previous study on liposome-mediated transfection of the human interferon-beta (HuIFN-beta) gene into subcutaneously implanted human gliomas in nude mice, we found that HuIFN-beta was produced and secreted by the tumor cells and that the growth of solid tumors was completely inhibited. The present study investig...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930590207

    authors: Harada K,Yoshida J,Mizuno M,Kurisu K,Uozumi T

    更新日期:1995-06-01 00:00:00

  • Long survival following combined treatment of inoperable cholangiocarcinoma: surgery, radiotherapy, and chemotherapy.

    abstract::A jaundiced patient due to inoperable bile duct carcinoma was treated by a combination of surgery, radiotherapy, and chemotherapy. At the operation an intra-abdominal, extra-choledochal bypass of the tumor was performed with a T-tube obstruction 10 months after diagnosis, and no evidence of malignancy was seen. The T-...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930130308

    authors: Hashmonai M,Lev L,Schramek A,Ben-Arieh Y,Robinson E

    更新日期:1980-01-01 00:00:00

  • Advancements in imaging technology for microvascular free tissue transfer.

    abstract::The use of preoperative imaging has become routine for many reconstructive microsurgeons to help localize perforators for planning of microvascular free flaps. However, with advancements in imaging technology, perforator mapping represents only one potential benefit as virtual planning and medical modeling, and flap t...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.25194

    authors: Chang EI,Chu CK,Chang EI

    更新日期:2018-10-01 00:00:00

  • Adjuvant chemotherapy after neoadjuvant chemoradiation and curative resection for rectal cancer: is it necessary for all patients?

    abstract:BACKGROUND:The benefit of adjuvant chemotherapy for patients with locally advanced rectal cancer who have received neoadjuvant concurrent chemoradiation therapy (CCRT) and undergone curative resection remains unclear. METHODS:This study was a retrospective review of prospectively collected data. Patients with locally ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23835

    authors: Jung KU,Kim HC,Park JO,Park YS,Park HC,Choi DH,Cho YB,Yun SH,Lee WY,Chun HK

    更新日期:2015-03-15 00:00:00

  • Endoscopic surveillance of patients following a curative resection for colorectal cancer.

    abstract::From 1974 to 1985, 161 patients were followed by at least one colonoscopy following a polypectomy for an adenomatous polyp. These patients had had a previous curative resection performed for colorectal carcinoma. The median follow-up time after surgery was 54 months. A polyp within 65 cm from the anal verge or from a ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930380204

    authors: Carlsson G,Petrelli NJ,Herrera L,Nava H,Mittelman A

    更新日期:1988-06-01 00:00:00

  • Radical cystectomy in patients over 80 years old in Quebec: A population-based study of outcomes.

    abstract:OBJECTIVES:To document radical cystectomy (RC) outcomes in patients over 80 years old across Quebec during the years 2000-2009 and to examine potentially related factors. METHODS:Within Quebec health insurance medical services database, we identified patients over 80 years who underwent RC. The outcomes analyzed were ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23887

    authors: Zakaria AS,Santos F,Tanguay S,Kassouf W,Aprikian AG

    更新日期:2015-06-01 00:00:00

  • Neoadjuvant FOLFOX chemotherapy in 34 consecutive patients with mucinous peritoneal carcinomatosis of appendiceal origin.

    abstract:BACKGROUND:A treatment option for patients with peritoneal mucinous carcinomatosis (PMCA) from an appendiceal neoplasm is cytoreductive surgery and perioperative intraperitoneal chemotherapy. Also, these patients are recommended for systemic chemotherapy using an oxaliplatin and 5-fluorouracil (FOLFOX) regimen. A major...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21679

    authors: Sugarbaker PH,Bijelic L,Chang D,Yoo D

    更新日期:2010-11-01 00:00:00

  • An apparent danazol-induced primary hepatocellular carcinoma: case report.

    abstract::This paper presents an apparent case of danazol-induced primary hepatocellular carcinoma in a 49-year-old patient, following two years of continuous therapy with this inhibitor of pituitary gonadotrophin. Discontinuation of the drug failed to cause regression of the tumour. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930280209

    authors: Buamah PK

    更新日期:1985-02-01 00:00:00

  • A computerized tumor-registry system for persons who do not love computers.

    abstract::A new simplified system for updating a cancer registry has been developed in the Biostatistics Department of Roswell Park Memorial Institute. It was designed to serve the needs of maintaining a registry for a cooperative cancer research group. The Data-Update Procedure at a Remote Terminal (DUPART) system has general ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930070508

    authors: Johnson IC,Blumenson LE,Bross ID

    更新日期:1975-01-01 00:00:00

  • Breast reconstruction with alloplastic implants.

    abstract::This article reviews immediate and delayed breast reconstruction with prosthetic implants, and the effect of irradiation therapy. Despite widespread use of breast conserving surgery for early breast cancer, many breast cancer patients still undergo mastectomy. Some of these patients choose breast reconstruction. Over ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.20484

    authors: Agha-Mohammadi S,De La Cruz C,Hurwitz DJ

    更新日期:2006-11-01 00:00:00

  • The efficacy of systematic lymph node dissection in advanced epithelial ovarian cancer during interval debulking surgery performed after neoadjuvant chemotherapy.

    abstract:BACKGROUND AND OBJECTIVE:The therapeutic role of systematic lymph node dissection (LND) remains unclear in advanced epithelial ovarian cancer (EOC), especially during interval debulking surgery (IDS) performed after neoadjuvant chemotherapy (NAC). We analyzed the therapeutic and prognostic roles of systematic LND in ad...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24669

    authors: Eoh KJ,Yoon JW,Lee I,Lee JY,Kim S,Kim SW,Kim YT,Nam EJ

    更新日期:2017-09-01 00:00:00