Biotransformation of halothane, enflurane, isoflurane, and desflurane to trifluoroacetylated liver proteins: association between protein acylation and hepatic injury.

abstract：BACKGROUND:Percutaneous cannulation of the femoral vein, in the pediatric age group, can be technically challenging, especially when performed by residents in training. We examined whether the use of real-time ultrasound guidance is superior to a landmark technique for femoral vein catheterization in children undergoin...

journal_title：Anesthesia and analgesia

authors： Aouad MT,Kanazi GE,Abdallah FW,Moukaddem FH,Turbay MJ,Obeid MY,Siddik-Sayyid SM

更新日期：2010-09-01 00:00:00

abstract：:The effects of commercial and crystalline solutions of chloroprocaine (CP) (1.6 X 10(-3)-0.4 X 10(-3)M) and sodium bisulfite (SB) (0.8 X 10(-3)-0.08 X 10(-3)M) were studied on the multiplication of human neuroblastoma cells. These cells were chosen because of putative neurotoxicity associated with CP; cell multiplicat...

journal_title：Anesthesia and analgesia

authors： Seravalli E,Lear E

更新日期：1987-10-01 00:00:00

abstract：:Animal studies suggest that increased circulating estrogen and progesterone, and activation of the endorphin system cause prenancy-induced antinociceptive effects. Human studies have provided inconsistent results and have often lacked a nonpregnant control group. In this study, we compared sensitivity to experimental ...

journal_title：Anesthesia and analgesia

authors： Carvalho B,Angst MS,Fuller AJ,Lin E,Mathusamy AD,Riley ET

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:QT interval prolongation is associated with torsades des pointes (TdP), but is a poor predictor of drug torsadogenicity. Susceptibility to TdP arises from increased transmural dispersion of repolarization (TDR) across the myocardial wall, rather than QT interval prolongation per se. TDR can be measured on th...

journal_title：Anesthesia and analgesia

authors： Whyte SD,Sanatani S,Lim J,Booker PD

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The incremental dose of opioids used in chronic pain management often leads to a reduced opioid analgesic effect, opioid misuse, and addiction. Central dopamine (DA) dysfunction contributes to the chronicity of pain and a decreased opioid analgesic effect. Methylphenidate (MPH/Ritalin) enhances central DA fu...

journal_title：Anesthesia and analgesia

authors： You Z,Ding W,Doheny JT,Shen S,Yang J,Yang L,Chen L,Zhu S,Mao J

更新日期：2020-02-01 00:00:00

abstract：:Our goal in this study was to develop a robotic intubation system and to conduct a feasibility pilot study on the use of a robotic intubation system for endotracheal intubations. The Kepler Intubation System was developed, consisting of a remote control center (joystick and intubation cockpit) linked to a standard vid...

journal_title：Anesthesia and analgesia

authors： Hemmerling TM,Wehbe M,Zaouter C,Taddei R,Morse J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:In this study, we sought to determine whether a simplified ultrasound measurement of the largest transverse diameter, using a standard ultrasound machine, could be used to diagnose postoperative urinary retention (POUR). This method may replace expensive bladder volume measuring devices or a more complex ult...

journal_title：Anesthesia and analgesia

authors： Daurat A,Choquet O,Bringuier S,Charbit J,Egan M,Capdevila X

更新日期：2015-05-01 00:00:00

abstract：:Ropivacaine, which blocks sensory nerve fibers more readily than motor fibers, is considered to be less potent than bupivacaine. Our hypothesis was that, when used in spinal anesthesia for day surgery, ropivacaine 15 and 20 mg would provide faster motor recovery than bupivacaine 10 mg. This prospective, randomized, do...

journal_title：Anesthesia and analgesia

authors： Kallio H,Snäll EV,Kero MP,Rosenberg PH

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:Decompression illness (DCI) is caused by bubble formation in the blood or tissues after a reduction in ambient pressure. Clinically, DCI may range from a trivial illness to paralysis, loss of consciousness, cardiovascular collapse, and death. Recompression is the universally accepted standard for the treat...

journal_title：Anesthesia and analgesia

authors： Bennett MH,Lehm JP,Mitchell SJ,Wasiak J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Many of the complications of mechanical ventilation are related to inappropriate endotracheal tube (ETT) cuff pressure. The aim of the current study was to evaluate the effectiveness of automatic cuff pressure closed-loop control in patients under prolonged intubation, where presence of carbon dioxide (CO2) ...

journal_title：Anesthesia and analgesia

authors： Efrati S,Bolotin G,Levi L,Zaaroor M,Guralnik L,Weksler N,Levinger U,Soroksky A,Denman WT,Gurman GM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is asso...

journal_title：Anesthesia and analgesia

authors： Rossi A,Burkhart C,Dell-Kuster S,Pollock BG,Strebel SP,Monsch AU,Kern C,Steiner LA

更新日期：2014-10-01 00:00:00

abstract：:A new mode of pulmonary ventilation called intratracheal pulmonary ventilation (ITPV) was studied. Briefly, a continuous flow of air/oxygen is introduced through a small catheter, the tip of which is positioned at the carina, with a diffuser mounted at its distal end. A timed expiration valve, when closed, provides fo...

journal_title：Anesthesia and analgesia

authors： Kolobow T,Powers T,Mandava S,Aprigliano M,Kawaguchi A,Tsuno K,Mueller E

更新日期：1994-03-01 00:00:00

abstract：:After Fontan repair in children, we performed a prospective, open-label study to evaluate the effect of amrinone on pulmonary vascular resistance (PVRI). Eight patients who underwent the Fontan repair had baseline arterial pressure, left atrial pressure, central venous pressure, and cardiac output measured postoperati...

journal_title：Anesthesia and analgesia

authors： Sorensen GK,Ramamoorthy C,Lynn AM,French J,Stevenson JG

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Although our understanding of nociceptive processing during anesthesia has increased greatly over the last decade, many patients still experience hyperalgesia and acute pain postoperatively. The noxious-induced withdrawal reflex (NIWR) model is specifically designed and validated to quantitatively study the ...

journal_title：Anesthesia and analgesia

authors： Sommers MG,Nguyen NK,Veening JG,Vissers KC,Ritskes-Hoitinga M,van Egmond J

更新日期：2008-04-01 00:00:00

abstract：UNLABELLED:Propofol has an antiemetic effect that may be mediated by gamma-aminobutyric acid (GABA) influences on the serotonin system, the mechanism of which is not known. We used three techniques, immunohistochemistry, High Performance Liquid Chromatography, and electrophysiology, to define propofol's effects on the ...

journal_title：Anesthesia and analgesia

authors： Cechetto DF,Diab T,Gibson CJ,Gelb AW

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify optimal target propofol and remifentanil concentrations to avoid a gag reflex in response to insertion of an upper gastrointestinal endoscope. METHODS:Patients presenting for endoscopy received target-controlled infusions (TCI) of both propofol and remifentanil for ...

journal_title：Anesthesia and analgesia

authors： Borrat X,Valencia JF,Magrans R,Gimenez-Mila M,Mellado R,Sendino O,Perez M,Nunez M,Jospin M,Jensen EW,Troconiz I,Gambus PL

更新日期：2015-07-01 00:00:00

abstract：:We evaluated empirically the extent to which the use of a cognitive aid during a high-fidelity simulation of a malignant hyperthermia (MH) event facilitated the correct and prompt treatment of MH. We reviewed the management of 48 simulated adult MH scenarios; 24 involving CA 1 and 24 involving CA 2 residents. In the C...

journal_title：Anesthesia and analgesia

authors： Harrison TK,Manser T,Howard SK,Gaba DM

更新日期：2006-09-01 00:00:00

abstract：IMPLICATIONS:Manipulating the density of local anesthetic solutions by using a simple formula may be clinically useful in producing optimal density solutions for spinal anesthesia under a variety of clinical conditions. ...

journal_title：Anesthesia and analgesia

authors： Hallworth SP,Fernando R,Stocks GM

更新日期：2002-06-01 00:00:00

abstract：:The effects of nitrous oxide-oxygen plus small doses of fentanyl with (N = 7) and without (N = 15) naloxone and the effects of nitrous oxide-oxygen plus halothane (N = 13) on plasma concentration of arginine vasopressin (AVP) and cortisol were studied in normal patients before and during gynecologic laparotomies. Pati...

journal_title：Anesthesia and analgesia

authors： Lehtinen AM,Fyhrquist F,Kivalo I

更新日期：1984-01-01 00:00:00

abstract：:Continuous positive airway pressure (CPAP) of 5 and 10 cm H2O applied to the nonventilated lung is effective in improving arterial oxygenation during one-lung ventilation (1-LV). The effectiveness of lower levels of CPAP on improving oxygenation, however, has not been reported, possibly because of limitations of previ...

journal_title：Anesthesia and analgesia

authors： Hogue CW Jr

更新日期：1994-08-01 00:00:00

abstract：:Response time (RT) of the Narkotest anesthetic gas monitor was measured for 7 inhalation anesthetics, using a 5 L/min fresh gas flow (FGF). Time to 63 percent of maximum response (RT63) and to 95 percent of maximum response (RT95) was directly related to rubber/gas and oil/gas partition coefficients. RT95 ranged from ...

journal_title：Anesthesia and analgesia

authors： Velazquez JL,Feingold A,Walther P

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:In acute lung injury, ventilation avoiding tidal hyperinflation and tidal recruitment has been proposed to prevent ventilator-associated lung injury. Information about dynamic recruitment may be obtained from the characteristics of pressure-volume (PV) curves or the profile of pressure-time (Paw-t) curves. ...

journal_title：Anesthesia and analgesia

authors： Henzler D,Hochhausen N,Dembinski R,Orfao S,Rossaint R,Kuhlen R

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Sugammadex is a modified [gamma] cyclodextrin compound, which encapsulates rocuronium to provide for a rapid reversal of residual neuromuscular blockade. We tested the hypothesis that sugammadex would provide for a more rapid reversal of a moderately profound residual rocuronium-induced blockade than the com...

journal_title：Anesthesia and analgesia

authors： Sacan O,White PF,Tufanogullari B,Klein K

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:We studied the in vitro effects of sevoflurane, isoflurane, and propofol anesthesia on platelet function. Thirty patients undergoing minor surgical procedures were divided into three groups (n = 10 each). Induction of anesthesia was achieved by using 5 mg/kg thiopental i.v., and 0.1 mg/kg vecuronium i.v. was...

journal_title：Anesthesia and analgesia

authors： Doğan IV,Ovali E,Eti Z,Yayci A,Göğüş FY

更新日期：1999-02-01 00:00:00

abstract：:We measured arterial plasma concentrations of lidocaine by enzyme immunoassay when 10 ml of 2% lidocaine without epinephrine was injected into the cervical, thoracic, or lumbar epidural spaces in 30 patients. There was no difference in the time courses of plasma levels of lidocaine. Peak concentrations were achieved 1...

journal_title：Anesthesia and analgesia

authors： Mayumi T,Dohi S,Takahashi T

更新日期：1983-06-01 00:00:00

abstract：:Cardioprotection by anesthetic preconditioning (APC) can be abolished by nitric oxide (NO*) synthase inhibitors or by reactive oxygen species (ROS) scavengers. We previously reported attenuated mitochondrial electron transport (ET) and increased ROS generation during preconditioning sevoflurane exposure as part of the...

journal_title：Anesthesia and analgesia

authors： Riess ML,Kevin LG,McCormick J,Jiang MT,Rhodes SS,Stowe DF

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:During mechanical ventilation of infants and neonates, small changes in tidal volume may lead to hypo- or hyperventilation, barotrauma, or volutrauma. Partly because breathing circuit compliance and fresh gas flow affect tidal volume delivery by traditional anesthesia ventilators in volume-controlled ventila...

journal_title：Anesthesia and analgesia

authors： Bachiller PR,McDonough JM,Feldman JM

更新日期：2008-05-01 00:00:00

abstract：UNLABELLED:In adult patients, the creation of pneumoperitoneum (PP) by means of carbon dioxide (CO(2)) insufflation leads to an increase in cerebral blood flow velocity (CBFV), which is thought to be caused by hypercapnia. We evaluated whether PP leads to an increase of CBFV in children, and whether this increase is di...

journal_title：Anesthesia and analgesia

authors： Huettemann E,Terborg C,Sakka SG,Petrat G,Schier F,Reinhart K

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Variations in the butyrylcholinesterase (BCHE) gene can prolong neuromuscular block after the administration of the neuromuscular blocking drugs succinylcholine and mivacurium. The most frequent variations in the BCHE gene are the atypical (A) and Kalow (K) variants. We, therefore, developed a detection appr...

journal_title：Anesthesia and analgesia

authors： Levano S,Keller D,Schobinger E,Urwyler A,Girard T

更新日期：2008-01-01 00:00:00

abstract：:General anesthesia results in increases in respiratory elastance and flow resistance within 10-15 min after induction. Stabilization (compensation) of the respiratory system in the face of this added load is related to the addition of active (contractile) force-length and force-velocity properties to its internal impe...

journal_title：Anesthesia and analgesia

authors： Baydur A,Sassoon CS,Stiles CM

更新日期：1986-01-01 00:00:00