Twenty-four hour ambulatory blood pressure in the population.

Abstract:

OBJECTIVES:To establish a population-based 24-h ambulatory blood pressure (ABP) reference material with day/night mean BP calculated by standardized and true bedtimes. DESIGN:A cross-sectional study of 200 randomly selected subjects (20 men and 20 women in each 10-year age interval 20-70 years) in Linköping, Sweden. SETTING:University Hospital of Linköping, Sweden. RESULTS:Participation rate was 67%. Mean supine clinic BP (CBP) and 24-h-ABP values for the whole material were 123 +/- 13/79 +/- 8 mmHg and 120 +/- 10/73 +/- 7 mmHg, respectively. White coat BP phenomenon increased with age (systolic CBP/ABP ratio versus age, r = 0.35, P < 0.0001). Seventeen participants had a night/day mean arterial blood pressure ratio > 0.9 (non-dipper) when calculated from their own time-notations. If standardized day (06.00-23.00) and night (23.00-06.00) limits were used, 24 subjects were non-dippers. Of these, only eight were 'true'. 'True' non-dippers had a similar day-time mean arterial ABP as 'true' dippers (92.4 +/- 11 mmHg versus 91.9 +/- 13 mmHg, P = 0.92) while night-time BP was higher (89.9 +/- 13 mmHg versus 74.1 +/- 7 mmHg, P < 0.0001). CONCLUSION:Population-based ABP reference values have been defined. We found 9% non-dippers and that standardized day/night-time limits may lead to misclassification. This could be due to gender- and age-differences in sleeping habits, which was also shown in this study. The frequency of white coat BP phenomenon increases with age.

journal_name

J Intern Med

authors

Nyström F,Malmström O,Karlberg BE,Ohman KP

doi

10.1046/j.1365-2796.1996.322856000.x

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

279-84

issue

5

eissn

0954-6820

issn

1365-2796

journal_volume

240

pub_type

杂志文章
  • Minimally invasive mitral valve surgery is associated with a low rate of complications.

    abstract::Minimally invasive mitral valve surgery is generally performed through a right minithoracotomy, in contrast to the traditional full median sternotomy approach. Minimally invasive mitral valve surgery is performed with increasing frequency, and by reducing surgical trauma, several observational studies suggest potentia...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12974

    authors: Kastengren M,Svenarud P,Ahlsson A,Dalén M

    更新日期:2019-12-01 00:00:00

  • The seasonal importance of serum 25-hydroxyvitamin D for bone mineral density in older women.

    abstract:BACKGROUND:The impact of season when determining a serum 25-hydroxyvitamin D (S-25OHD) cut-off level for optimal bone health is unknown. OBJECTIVE:To investigate the relative importance of S-25OHD for bone mineral density (BMD) by season. METHODS:A subcohort of 5002 Swedish women (mean age 68 years), randomly selecte...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.12563

    authors: Michaëlsson K,Wolk A,Byberg L,Mitchell A,Mallmin H,Melhus H

    更新日期:2017-02-01 00:00:00

  • Autoimmunity in atherosclerosis: a protective response losing control?

    abstract::Atherosclerosis is a chronic inflammatory disease characterized by accumulation of oxidized lipoproteins, increased cell death and hypertrophic degeneration of the arterial intima. The disease process is associated with local formation of modified self antigens that are targeted by both innate and adaptive immune resp...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.2008.01945.x

    authors: Nilsson J,Hansson GK

    更新日期:2008-05-01 00:00:00

  • A prospective study on antibody response to repeated vaccinations with pneumococcal capsular polysaccharide in splenectomized individuals with special reference to Hodgkin's lymphoma.

    abstract:BACKGROUND:Splenectomy is accompanied by a life-long risk of overwhelming postsplenectomy infection (OPSI), mainly caused by polysaccharide (PS) encapsulated bacteria such as Streptococcus pneumoniae. Despite extensive prophylactic efforts the mortality and morbidity rates remain high. The present study was based on a ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2004.01312.x

    authors: Landgren O,Björkholm M,Konradsen HB,Söderqvist M,Nilsson B,Gustavsson A,Axdorph U,Kalin M,Grimfors G

    更新日期:2004-06-01 00:00:00

  • Modulating T-cell homeostasis with IL-7: preclinical and clinical studies.

    abstract::Interleukin-7 (IL-7) is required for the development and survival of T cells and plays a critical role in modulating T-cell homeostasis. This review will address current understanding of IL-7 biology, review recent clinical experiences and discuss potential future clinical applications of IL-7, or IL-7 blockade, in th...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.2009.02085.x

    authors: Capitini CM,Chisti AA,Mackall CL

    更新日期:2009-08-01 00:00:00

  • The required beta cell research for improving treatment of type 2 diabetes.

    abstract::In healthy individuals, insulin resistance is associated with physiological conditions such as pregnancy or body weight gain and triggers an increase in beta cell number and insulin secretion capacity to preserve normoglycaemia. Failure of this beta cell compensation capacity is a fundamental cause of diabetic hypergl...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12096

    authors: Thorens B

    更新日期:2013-09-01 00:00:00

  • Circulating biomarkers of angiogenesis as indicators of left ventricular systolic dysfunction amongst patients with coronary artery disease.

    abstract:BACKGROUND:Patients with coronary artery disease (CAD) and left ventricular systolic dysfunction (LVSD) are often asymptomatic. Angiogenesis is implicated in the physiology of vascular repair and cardiac remodelling, and is one of many pathophysiological processes implicated in heart failure. We hypothesized that plasm...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2008.02057.x

    authors: Patel JV,Abraheem A,Chackathayil J,Gunning M,Creamer J,Hughes EA,Lip GY

    更新日期:2009-05-01 00:00:00

  • Types of diabetes treatment in a total, Norwegian, adult population. The Nord-Trøndelag Diabetes Study.

    abstract:OBJECTIVES:To describe types of diabetes treatment in a total, adult population, including those on no antidiabetic medication, and to evaluate use of the defined daily doses in estimation of diabetes prevalence. DESIGN:Cross-sectional epidemiologic survey applying patient-based questionnaires and clinical examination...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1994.tb00793.x

    authors: Midthjell K,Holmen J,Bjørndal A

    更新日期:1994-09-01 00:00:00

  • The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies.

    abstract::The Swedish Twin Registry (STR), which today has developed into a unique resource, was first established in the late 1950s to study the importance of smoking and alcohol consumption on cancer and cardiovascular diseases whilst controlling for genetic propensity to disease. Since that time, the Registry has been expand...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.2002.01032.x

    authors: Lichtenstein P,De Faire U,Floderus B,Svartengren M,Svedberg P,Pedersen NL

    更新日期:2002-09-01 00:00:00

  • Treatment with apo B peptide vaccines inhibits atherosclerosis in human apo B-100 transgenic mice without inducing an increase in peptide-specific antibodies.

    abstract:OBJECTIVES:Autoantibodies to apolipoprotein (apo) B-100 peptides are present in human plasma and have been shown to be associated with decreased cardiovascular risk. The present study aimed to determine if apo B-100 peptide vaccines are atheroprotective in mice expressing human apo B-100 and if the effectiveness of the...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2008.01995.x

    authors: Fredrikson GN,Björkbacka H,Söderberg I,Ljungcrantz I,Nilsson J

    更新日期:2008-12-01 00:00:00

  • Climate change: present and future risks to health, and necessary responses.

    abstract::Recent observed changes in Earth's climate, to which humans have contributed substantially, are affecting various health outcomes. These include altered distributions of some infectious disease vectors (ticks at high latitudes, malaria mosquitoes at high altitudes), and an uptrend in extreme weather events and associa...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.2011.02415.x

    authors: McMichael AJ,Lindgren E

    更新日期:2011-11-01 00:00:00

  • Evolving biomarkers improve prediction of long-term mortality in patients with stable coronary artery disease: the BIO-VILCAD score.

    abstract:OBJECTIVE:Algorithms to predict the future long-term risk of patients with stable coronary artery disease (CAD) are rare. The VIenna and Ludwigshafen CAD (VILCAD) risk score was one of the first scores specifically tailored for this clinically important patient population. The aim of this study was to refine risk predi...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.12189

    authors: Kleber ME,Goliasch G,Grammer TB,Pilz S,Tomaschitz A,Silbernagel G,Maurer G,März W,Niessner A

    更新日期:2014-08-01 00:00:00

  • Hyaluronan turnover in relation to infection and sepsis.

    abstract::Sepsis is a major clinical problem in intensive care. The mortality in septic shock is high, and predominantly due to cardiovascular collapse and multiple organ dysfunction. In sepsis high levels of circulating hyaluronan have been found, correlating to disease severity and prognosis. The reason behind the increased l...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.1997.00177.x

    authors: Berg S

    更新日期:1997-07-01 00:00:00

  • Physical activity and risk of cognitive decline: a meta-analysis of prospective studies.

    abstract:OBJECTIVE:The relationship between physical activity and cognitive function is intriguing but controversial. We performed a systematic meta-analysis of all the available prospective studies that investigated the association between physical activity and risk of cognitive decline in nondemented subjects. METHODS:We con...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1365-2796.2010.02281.x

    authors: Sofi F,Valecchi D,Bacci D,Abbate R,Gensini GF,Casini A,Macchi C

    更新日期:2011-01-01 00:00:00

  • Acetazolamide-associated aplastic anaemia.

    abstract::Eleven cases of acetazolamide-associated aplastic anaemia were reported in Sweden during a 17-year period. There were six women and five men with a median age of 71 years (range 63-85 years). The median dose of acetazolamide was 500 mg, and the median duration of treatment was 3 months (range 2-71 months). Ten of the ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1990.tb00290.x

    authors: Keisu M,Wiholm BE,Ost A,Mortimer O

    更新日期:1990-12-01 00:00:00

  • Bone metabolism in ochronotic patients.

    abstract::We investigated skeletal involvement in five male and two female patients with ochronosis, aged 26-82 years. The main parameters of mineral metabolism, together with biochemical markers of bone resorption (urinary N-telopeptides of type I collagen) and formation (serum bone isoenzyme of alkaline phosphatase and serum ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2003.01145.x

    authors: Aliberti G,Pulignano I,Schiappoli A,Minisola S,Romagnoli E,Proietta M

    更新日期:2003-09-01 00:00:00

  • Diabetes mellitus is a strong negative prognostic factor in patients with myocardial infarction treated with thrombolytic therapy.

    abstract:OBJECTIVES:To assess the long-term prognostic values of baseline demographic data, occurrence of vectorcardiographic signs of reperfusion, left ventricular function and coronary angiographic features. DESIGN:Longitudinal study of morbidity and mortality. SETTING:Coronary care unit at Danderyd Hospital, Stockholm, Swe...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2000.00007.x

    authors: Strandberg LE,Ericsson CG,O'Konor ML,Bergstrand L,Lundin P,Rehnqvist N,Tornvall P

    更新日期:2000-08-01 00:00:00

  • Chronic mesenteric ischaemia: diagnostic challenges and treatment options.

    abstract:OBJECTIVES:A description of the clinical presentation, diagnostic procedure and mode of therapy in three patients suffering from chronic mesenteric ischaemia. DESIGN AND INTERVENTIONS:In all cases, the diagnosis was made on the basis of abdominal complaints in combination with angiographic findings. The primary treatm...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1995.tb01178.x

    authors: Hoogenberg K,Van Essen LH,Van den Dungen JJ,Limburg AJ,Boeve WJ,Kleibeuker JH

    更新日期:1995-03-01 00:00:00

  • Bradydysrhythmia-related presyncope secondary to pheochromocytoma.

    abstract::Pheochromocytoma endures as a life-threatening disorder. In the absence of systemic hypertension, diagnosis may be difficult. We present a 46-year-old normotensive male with a history of presyncope. One of these episodes could be documented, and revealed symptomatic bradycardia suspicious of sinus node arrest. Due to ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.1997.00198.x

    authors: Zweiker R,Tiemann M,Eber B,Schumacher M,Fruhwald FM,Lipp R,Lax S,Pristautz H,Klein W

    更新日期:1997-09-01 00:00:00

  • Neural stimulations regulate the infiltration of immune cells into the CNS.

    abstract::The systemic regulation of immune reactions by the nervous system is well studied and depends on the release of hormones. Some regional regulations of immune reactions, on the other hand, depend on specific neural pathways. Better understanding of these regulations will expand therapeutic applications for neuroimmune ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12912

    authors: Kamimura D,Murakami M

    更新日期:2019-09-01 00:00:00

  • Combination of budesonide/formoterol more effective than fluticasone/salmeterol in preventing exacerbations in chronic obstructive pulmonary disease: the PATHOS study.

    abstract:OBJECTIVES:Combinations of inhaled corticosteroids (ICSs) and long-acting β2 -agonists (LABAs) are recommended for patients with moderate and severe chronic obstructive pulmonary disease (COPD). However, it is not known whether different fixed combinations are equally effective. The aim of this study was to investigate...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.12067

    authors: Larsson K,Janson C,Lisspers K,Jørgensen L,Stratelis G,Telg G,Ställberg B,Johansson G

    更新日期:2013-06-01 00:00:00

  • A multimarker risk stratification approach to non-ST elevation acute coronary syndrome: implications of troponin T, CRP, NT pro-BNP and fibrin D-dimer levels.

    abstract:INTRODUCTION:Biomarkers have emerged as interesting predictors of risk in non-ST elevation acute coronary syndromes (non-ST ACS). The aim of this study was to define the utility of the combined measurement of troponin T (TnT), C-reactive protein (CRP), NT pro-brain natriuretic peptide (NT pro-BNP) and D-dimer as biomar...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2007.01871.x

    authors: Tello-Montoliu A,Marín F,Roldán V,Mainar L,López MT,Sogorb F,Vicente V,Lip GY

    更新日期:2007-12-01 00:00:00

  • Frequency and effect of optimal anticoagulation before onset of ischaemic stroke in patients with known atrial fibrillation.

    abstract:BACKGROUND:The aims of the study were (i) to examine which antithrombotic therapy patients with known atrial fibrillation use at the point of time when they suffer an ischaemic stroke, (ii) to evaluate the effects of optimal antithrombotic treatment on outcome and severity of the stroke. METHODS:Patients with known at...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2005.01512.x

    authors: Indredavik B,Rohweder G,Lydersen S

    更新日期:2005-08-01 00:00:00

  • Folic acid absorption in patients infected with the human immunodeficiency virus.

    abstract::To determine the folic acid absorption characteristics of patients with human immunodeficiency virus (HIV) infection, a prospective, controlled, result-blind single-dose oral absorption study was conducted. A total of 25 subjects were fasted and given 5 mg oral folic acid; blood samples were taken at time zero and aft...

    journal_title:Journal of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2796.1991.tb00435.x

    authors: Revell P,O'Doherty MJ,Tang A,Savidge GF

    更新日期:1991-09-01 00:00:00

  • Connecting the brain cholesterol and renin-angiotensin systems: potential role of statins and RAS-modifying medications in dementia.

    abstract::Millions of people worldwide receive agents targeting the renin-angiotensin system (RAS) to treat hypertension or statins to lower cholesterol. The RAS and cholesterol metabolic pathways in the brain are autonomous from their systemic counterparts and are interrelated through the cholesterol metabolite 27-hydroxychole...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12838

    authors: Petek B,Villa-Lopez M,Loera-Valencia R,Gerenu G,Winblad B,Kramberger MG,Ismail MA,Eriksdotter M,Garcia-Ptacek S

    更新日期:2018-12-01 00:00:00

  • Chronic rhinosinusitis is associated with prolonged SARS-CoV2 RNA shedding in upper respiratory tract samples: A case-control study.

    abstract:BACKGROUND:SARS-CoV-2, the COVID-19 causative agent, has infected millions of people and killed over 1.6 million worldwide. A small percentage of cases persist with prolonged positive RT-PCR on nasopharyngeal swabs. The aim of this study was to determine risk factors for prolonged viral shedding amongst patient's basal...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.13237

    authors: Recalde-Zamacona B,Tomás-Velázquez A,Campo A,Satrústegui-Alzugaray B,Fernández-Alonso M,Iñigo M,Rodríguez-Mateos M,Di Frisco M,Felgueroso C,Bertó J,Marín-Oto M,Alcaide AB,Zulueta JJ,Seijo L,Landecho MF

    更新日期:2020-12-29 00:00:00

  • Effects of isometric exercise and heart rate on left ventricular filling pattern assessed by pulsed Doppler echocardiography.

    abstract::Left ventricular filling pattern was assessed by pulsed Doppler echocardiography at rest and during handgrip exercise in 33 healthy middle-aged subjects. The peak mitral flow-velocities during the early rapid filling phase (E) and during late (atrial) filling (A) were measured and the ratio of these peak flow-velociti...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1989.tb01388.x

    authors: Airaksinen KE,Ikäheimo MJ,Huikuri HV,Koistinen MJ,Linnaluoto M,Takkunen JT

    更新日期:1989-10-01 00:00:00

  • Renal failure due to sulphadiazine in AIDS patients with cerebral toxoplasmosis.

    abstract::Cerebral toxoplasmosis is optimally treated with the combination of high doses of sulphadiazine and pyrimethamine. We described two patients with AIDS treated for cerebral toxoplasmosis who developed renal failure due to sulphadiazine-induced crystalluria. Symptoms and renal failure were rapidly reversed with urine al...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1993.tb00685.x

    authors: Fariñas MC,Echevarría S,Sampedro I,González A,Pérez del Molino A,González-Macías J

    更新日期:1993-04-01 00:00:00

  • Fibrinogen and mortality in chronic critical limb ischaemia.

    abstract:OBJECTIVE:Plasma fibrinogen predicts cardiovascular events in patients with stable peripheral arterial occlusive disease, but its predictive value in patients with chronic critical limb ischaemia, a condition associated with a high risk of death, is unknown. DESIGN:A prospective cohort study. SETTING:Determination of...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.1999.00410.x

    authors: Pedrinelli R,Dell' Omo G,Barchielli A,Berchiolli R,Melillo E,Mariani M,Balbarini A,Ferrari M

    更新日期:1999-01-01 00:00:00

  • A conceptual time window-based model for the early stratification of trauma patients.

    abstract::Progress in the testing of therapies targeting the immune response following trauma, a leading cause of morbidity and mortality worldwide, has been slow. We propose that the design of interventional trials in trauma would benefit from a scheme or platform that could support the identification and implementation of pro...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12874

    authors: Lamparello AJ,Namas RA,Constantine G,McKinley TO,Elster E,Vodovotz Y,Billiar TR

    更新日期:2019-07-01 00:00:00