当前位置： SCI文献检索 > SCHIZOPHRENIA RESEARCH期刊下所有文献 > Further evidence for an association between schizophrenia and the HLA DQB1 gene locus.

Further evidence for an association between schizophrenia and the HLA DQB1 gene locus.

Abstract：

:A case-control study was conducted in Singapore, in order to examine a proposed association between schizophrenia and the HLA DQB1 gene locus. The probands were male inpatients of Chinese ethnicity with schizophrenia (ICD-10 criteria, n = 102) and the controls were adults matched for gender and ethnicity (n = 111). Polymorphisms of the HLA DQB1 gene were examined using molecular typing by reverse dot-blotting (MTRB), a novel PCR based method. Among the patients, a positive association with HLA DQB1*0303 (odds ratio 4.46, C.I. 1.63, 12.17), as well as a negative association with HLA DQB1*0602 (odds ratio 0.22, C.I. 0.18, 0.83) was detected.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Nimgaonkar VL,Rudert WA,Zhang XR,Tsoi WF,Trucco M,Saha N

doi

10.1016/0920-9964(95)00023-2

subject

Has Abstract

pub_date

1995-12-01 00:00:00

pages

43-9

issue

1

eissn

0920-9964

issn

1573-2509

pii

0920996495000232

journal_volume

18

pub_type

杂志文章

相关文献

SCHIZOPHRENIA RESEARCH文献大全
  • Verbal memory impairment in healthy siblings of patients with schizophrenia.

    abstract：:Cognitive deficits have been recognized as a core feature of schizophrenia (SZ) and are present in most patients. Verbal memory (VM), working memory (WM), and executive function (EF) are domains commonly impaired in patients with SZ. These latter domains have been related to the genetic risk of the disorder characteri...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2013.08.019

    authors： Massuda R,Bücker J,Czepielewski LS,Narvaez JC,Pedrini M,Santos BT,Teixeira AS,Souza AL,Vasconcelos-Moreno MP,Vianna-Sulzbach M,Goi PD,Belmonte-de-Abreu P,Gama CS

    更新日期：2013-11-01 00:00:00

  • Symptomatic remission and associated factors in a catchment area based population of older patients with schizophrenia.

    abstract：BACKGROUND:Symptomatic remission and its associated factors have been evaluated in several studies of younger schizophrenic patients. Although the number of older individuals with schizophrenia is rapidly growing, evaluations of remission in elderly patients are scarce and limited to samples of convenience, questioning...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2010.09.003

    authors： Meesters PD,Comijs HC,de Haan L,Smit JH,Eikelenboom P,Beekman AT,Stek ML

    更新日期：2011-03-01 00:00:00

  • Neuroimaging predictors of functional outcomes in schizophrenia at baseline and 6-month follow-up.

    abstract：PURPOSE:Studies show that deficit syndrome schizophrenia patients, characterized by primary negative symptoms and poor functional outcome, have impairment in specific neural circuits. We assessed whether these same neural circuits are directly linked to functional outcomes across schizophrenia patients. METHODS:T1- an...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.10.023

    authors： Behdinan T,Foussias G,Wheeler AL,Stefanik L,Felsky D,Remington G,Rajji TK,Mallar Chakravarty M,Voineskos AN

    更新日期：2015-12-01 00:00:00

  • Abnormal white matter integrity in antipsychotic-naïve first-episode psychosis patients assessed by a DTI principal component analysis.

    abstract：INTRODUCTION:Diffusion tensor imaging (DTI) studies in patients with schizophrenia have shown abnormalities in the microstructure of white matter tracts. Specifically, reduced fractional anisotropy (FA) has been described across multiple white matter tracts, in studies that have mainly included patients treated with an...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.01.019

    authors： Alvarado-Alanis P,León-Ortiz P,Reyes-Madrigal F,Favila R,Rodríguez-Mayoral O,Nicolini H,Azcárraga M,Graff-Guerrero A,Rowland LM,de la Fuente-Sandoval C

    更新日期：2015-03-01 00:00:00

  • Cases of remission of psychosis following resection of pheochromocytoma or paraganglioma.

    abstract：:The author previously proposed that schizophrenia has similar cytokine expression compared to melanoma, a neural crest cell tumor. One possible tumor model of schizophrenia includes anti-NMDA receptor encephalitis, a paraneoplastic syndrome. While examining the possible relationship of neural crest cell tumors to schi...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.08.012

    authors： Brown JS Jr

    更新日期：2016-10-01 00:00:00

  • Longitudinal consent-related abilities among research participants with schizophrenia: results from the CATIE study.

    abstract：OBJECTIVE:Research participants must have adequate consent-related abilities to provide informed consent at the time of study enrollment. We sought to determine if research participants with schizophrenia maintain adequate consent-related abilities during a longitudinal study. If participants lose abilities during a tr...

    journal_title：Schizophrenia research

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/j.schres.2011.04.012

    authors： Stroup TS,Appelbaum PS,Gu H,Hays S,Swartz MS,Keefe RS,Kim SY,Manschreck TC,Boshes RA,McEvoy JP,Lieberman JA

    更新日期：2011-08-01 00:00:00

  • High-dose galantamine augmentation inferior to placebo on attention, inhibitory control and working memory performance in nonsmokers with schizophrenia.

    abstract：:Dysfunction in the neuronal nicotinic acetylcholine receptor (nAChR) system has been implicated in the pathophysiology of schizophrenia, and it has been postulated that treatments that increase nAChR activity may improve symptoms of the disorder. We investigated the effects of the acetylcholinesterase inhibitor and al...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2007.12.491

    authors： Dyer MA,Freudenreich O,Culhane MA,Pachas GN,Deckersbach T,Murphy E,Goff DC,Evins AE

    更新日期：2008-07-01 00:00:00

  • Self-reported sleep disturbances associated with procedural learning impairment in adolescents at ultra-high risk for psychosis.

    abstract：:Sleep disturbance contributes to impaired procedural learning in schizophrenia, yet little is known about this relationship prior to psychosis onset. Adolescents at ultra high-risk (UHR; N=62) for psychosis completed the Pittsburgh Sleep Quality Index (PSQI) and a procedural learning task (Pursuit Rotor). Increased se...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.03.025

    authors： Lunsford-Avery JR,Dean DJ,Mittal VA

    更新日期：2017-12-01 00:00:00

  • Increased resting-state global functional connectivity density of default mode network in schizophrenia subjects treated with electroconvulsive therapy.

    abstract：:Modified electroconvulsive therapy (MECT) has been widely applied to help treat schizophrenia patients who are treatment-resistant to pharmaceutical therapy. Although the technique is increasingly prevalent, the underlying neural mechanisms have not been well clarified. We conducted a longitudinal study to investigate...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.10.044

    authors： Huang H,Jiang Y,Xia M,Tang Y,Zhang T,Cui H,Wang J,Li Y,Xu L,Curtin A,Sheng J,Jia Y,Yao D,Li C,Luo C,Wang J

    更新日期：2018-07-01 00:00:00

  • A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia.

    abstract：BACKGROUND:Targeting glutamatergic dysfunction provides an exciting opportunity to improve cognitive impairment in schizophrenia. One treatment approach has targeted inadequate antioxidant defenses at glutamatergic synapses. Animal and human data suggest NMDA antagonists worsen executive cognitive controls--e.g. increa...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.schres.2012.10.001

    authors： Chengappa KN,Turkin SR,DeSanti S,Bowie CR,Brar JS,Schlicht PJ,Murphy SL,Hetrick ML,Bilder R,Fleet D

    更新日期：2012-12-01 00:00:00

  • Trajectories of change in self-reported psychotic-like experiences in childhood and adolescence.

    abstract：BACKGROUND:Psychotic-like experiences (PLEs) during adolescence are not uncommon and potentially represent a clinical and public health concern. A greater understanding of their aetiology and patterns of change over time is needed. We aimed to describe trajectories of PLEs during adolescence, and examine their associat...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.06.024

    authors： Thapar A,Heron J,Jones RB,Owen MJ,Lewis G,Zammit S

    更新日期：2012-09-01 00:00:00

  • Hippocampal and orbital inferior frontal gray matter volume abnormalities and cognitive deficit in treatment-naive, first-episode patients with schizophrenia.

    abstract：BACKGROUND:Cognitive impairment is a core feature of schizophrenia. Some evidence suggests an association between cognition deficits and gray matter reductions. In this study, we investigated the relationship between cognitive performance and gray matter volumes in patients with treatment-naïve, first-episode schizophr...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2013.12.015

    authors： Guo X,Li J,Wang J,Fan X,Hu M,Shen Y,Chen H,Zhao J

    更新日期：2014-02-01 00:00:00

  • Revisiting the International Physical Activity Questionnaire (IPAQ): Assessing physical activity among individuals with schizophrenia.

    abstract：BACKGROUND:Individuals with schizophrenia tend to have low levels of physical activity (PA) which contributes to high rates of physical comorbidities. Valid and reliable methods of assessing PA are essential for advancing health research. Ten years after initial validation of the Short-Form International Physical Activ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.09.010

    authors： Duncan MJ,Arbour-Nicitopoulos K,Subramanieapillai M,Remington G,Faulkner G

    更新日期：2017-01-01 00:00:00

  • Measuring theory of mind in schizophrenia research: Cross-cultural validation.

    abstract：:Theory of mind (ToM) is the ability to understand mental states of others and it is crucial for building sensitivity to other persons or events. Measuring ToM is important for understanding and rehabilitating social cognitive impairments in persons with schizophrenia. The Social Attribution Task-Multiple Choice (SAT-M...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2018.06.022

    authors： Lee HS,Corbera S,Poltorak A,Park K,Assaf M,Bell MD,Wexler BE,Cho YI,Jung S,Brocke S,Choi KH

    更新日期：2018-11-01 00:00:00

  • Characterizing trajectories of cognitive functioning in older adults with schizophrenia: does method matter?

    abstract：BACKGROUND:Heterogeneity in clinical outcomes may be caused by factors working at multiple levels, e.g., between groups, between subjects, or within subjects over time. A more nuanced assessment of differences in variation among schizophrenia patients and between patients and healthy comparison subjects can clarify eti...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.10.033

    authors： Thompson WK,Savla GN,Vahia IV,Depp CA,O'Hara R,Jeste DV,Palmer BW

    更新日期：2013-01-01 00:00:00

  • Effect of psychotropic drug treatment on sterol metabolism.

    abstract：:Cholesterol metabolism is vital for brain function. Previous work in cultured cells has shown that a number of psychotropic drugs inhibit the activity of 7-dehydrocholesterol reductase (DHCR7), an enzyme that catalyzes the final steps in cholesterol biosynthesis. This leads to the accumulation of 7-dehydrocholesterol ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.02.001

    authors： Korade Ž,Liu W,Warren EB,Armstrong K,Porter NA,Konradi C

    更新日期：2017-09-01 00:00:00

  • Meta-analysis of glucose tolerance, insulin, and insulin resistance in antipsychotic-naïve patients with nonaffective psychosis.

    abstract：BACKGROUND:Some studies have suggested that antipsychotic-naïve patients with nonaffective psychosis (NAP) have glucose intolerance. AIMS:To conduct a systematic review and meta-analysis of fasting glucose (FG), two hour values in the oral glucose tolerance test (2HG), fasting insulin concentration (INS), and insulin ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.schres.2016.09.026

    authors： Greenhalgh AM,Gonzalez-Blanco L,Garcia-Rizo C,Fernandez-Egea E,Miller B,Arroyo MB,Kirkpatrick B

    更新日期：2017-01-01 00:00:00

  • Insight in early psychosis: a 1-year follow-up.

    abstract：:Insight was investigated in 180 individuals consecutively admitted to a comprehensive early psychosis treatment program. Insight was assessed on admission and after 3, 6 and 12 months. Insight improved significantly over 12 months, and was negatively correlated with both positive and negative symptoms, and positively ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/S0920-9964(03)00047-1

    authors： Mintz AR,Addington J,Addington D

    更新日期：2004-04-01 00:00:00

  • Deficit of entropy modulation of the EEG in schizophrenia associated to cognitive performance and symptoms. A replication study.

    abstract：:Spectral entropy (SE) is a measurement from information theory field that provides an estimation of EEG regularity and may be useful as a summary of its spectral properties. Previous studies using small samples reported a deficit of EEG entropy modulation in schizophrenia during cognitive activity. The present study i...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.08.057

    authors： Molina V,Bachiller A,Gomez-Pilar J,Lubeiro A,Hornero R,Cea-Cañas B,Valcárcel C,Haidar MK,Poza J

    更新日期：2018-05-01 00:00:00

  • Bone mineral density as a marker of cumulative endogenous estrogen exposure: relationship to background genetic risk of psychotic disorder.

    abstract：BACKGROUND:Alterations in bone mineral density (BMD) in patients with psychotic disorder may reflect the effect of treatment (disease effect observed in patients but not their siblings) or, as an intermediate marker of cumulative endogenous estrogen exposure, alterations in the neuroprotective effect of estrogen in the...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.10.031

    authors： van der Leeuw C,Habets P,Domen P,van Kroonenburgh M,van Os J,Marcelis M,for G.R.O.U.P.

    更新日期：2013-01-01 00:00:00

  • Sex versus gender differences in schizophrenia: The case for normal personality differences.

    abstract：:Schizophrenia has generally been viewed as having a unique preschizophrenia personality or destructive to the personality post-onset. This view is reflected in the scarcity of studies of personality in schizophrenia with the exception of schizotypal personality considered by many as an endophenotype of schizophrenia. ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.02.015

    authors： Lewine R,Martin M,Hart M

    更新日期：2017-11-01 00:00:00

  • Postmortem studies on mitochondria in schizophrenia.

    abstract：:The aim of this paper is to provide a brief review of mitochondrial structure as it relates to function and then present abnormalities in mitochondria in postmortem schizophrenia with a focus on ultrastructure. Function, morphology, fusion, fission, motility, ΔΨmem, ATP production, mitochondrial derived vesicles, and ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,评审

    doi：10.1016/j.schres.2017.01.056

    authors： Roberts RC

    更新日期：2017-09-01 00:00:00

  • A potential role for adjunctive omega-3 polyunsaturated fatty acids for depression and anxiety symptoms in recent onset psychosis: Results from a 16 week randomized placebo-controlled trial for participants concurrently treated with risperidone.

    abstract：:Omega-3 treatment studies for multi-episode schizophrenia or clinical high risk for conversion to psychosis states have had variable, and often negative, results. To examine adjunctive omega-3 treatment for recent onset psychosis, participants aged 15-40 years with recent onset schizophrenia-spectrum (n = 46) or bipol...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2018.09.006

    authors： Robinson DG,Gallego JA,John M,Hanna LA,Zhang JP,Birnbaum ML,Greenberg J,Naraine M,Peters BD,McNamara RK,Malhotra AK,Szeszko PR

    更新日期：2019-02-01 00:00:00

  • Learning potential on the WCST in schizophrenia is related to the neuronal integrity of the anterior cingulate cortex as measured by proton magnetic resonance spectroscopy.

    abstract：BACKGROUND:In recent years, schizophrenia has increasingly been recognized as a neurocognitive disorder, which has led to a growing literature on cognitive rehabilitation, and suggested several potential enhancements to cognitive function. For instance, it has been shown that executive functioning deficits as measured ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2008.08.005

    authors： Ohrmann P,Kugel H,Bauer J,Siegmund A,Kölkebeck K,Suslow T,Wiedl KH,Rothermundt M,Arolt V,Pedersen A

    更新日期：2008-12-01 00:00:00

  • Prolonged haloperidol and reduced haloperidol plasma concentrations after decanoate withdrawal.

    abstract：:Haloperidol and reduced haloperidol plasma concentrations were measured in twelve schizophrenic patients upon cessation of haloperidol decanoate (HLD) treatment. Each patient received HLD 100 mg every 4 weeks for five injections. After the fifth injection, HLD was discontinued. Haloperidol and reduced haloperidol plas...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/0920-9964(93)90007-6

    authors： Chang WH,Lin SK,Juang DJ,Chen LC,Yang CH,Hu WH,Chien CP,Lam YW,Jann MW

    更新日期：1993-03-01 00:00:00

  • Omega-3 fatty acid supplementation may prevent loss of gray matter thickness in the left parieto-occipital cortex in first episode schizophrenia: A secondary outcome analysis of the OFFER randomized controlled study.

    abstract：:The aim of the study was to assess changes in cortical thickness related to the use of n-3 polyunsaturated fatty acids (PUFA) as add-on therapy in patients with first episode schizophrenia. A double-blind randomized controlled study was conducted using a 26-week intervention composed of concentrated fish oil containin...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2017.10.013

    authors： Pawełczyk T,Piątkowska-Janko E,Bogorodzki P,Gębski P,Grancow-Grabka M,Trafalska E,Żurner N,Pawełczyk A

    更新日期：2018-05-01 00:00:00

  • Cognitive and brain function in schizotypal personality disorder.

    abstract：:Schizotypal personality disorder, a diagnosis defined partially in terms of a genetic relatedness to schizophrenia, has begun to receive extensive investigative study. While the exact etiologic relationship between schizotypal personality disorder and schizophrenia remains to be determined, three models have been cons...

    journal_title：Schizophrenia research

    pub_type：

    doi：10.1016/s0920-9964(01)00363-2

    authors： Siever LJ,Koenigsberg HW,Harvey P,Mitropoulou V,Laruelle M,Abi-Dargham A,Goodman M,Buchsbaum M

    更新日期：2002-03-01 00:00:00

  • Examining hippocampal function in schizophrenia using a virtual reality spatial navigation task.

    abstract：BACKGROUND:Structural pathology in the hippocampus is well-documented in schizophrenia, but brain functional changes have not been consistently found. We used spatial navigation in a virtual reality environment, a task that is known to produce robust hippocampal activation in healthy subjects, to examine task-related a...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.02.033

    authors： Salgado-Pineda P,Landin-Romero R,Portillo F,Bosque C,Pomes A,Spanlang B,Franquelo JC,Teixido C,Sarró S,Salvador R,Slater M,Pomarol-Clotet E,McKenna PJ

    更新日期：2016-04-01 00:00:00

  • Insulin secretion in patients receiving clozapine, olanzapine, quetiapine and risperidone.

    abstract：BACKGROUND:Second-generation antipsychotics (SGAs) increase the risk of type 2 diabetes. The mechanism is thought to center on drug-induced weight gain, which starts the dysmetabolic cascade of insulin resistance, increased insulin production and pancreatic beta-cell failure. An independent effect of SGAs on insulin se...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.11.016

    authors： Manu P,Correll CU,Wampers M,van Winkel R,Yu W,Shiffeldrim D,Kane JM,De Hert M

    更新日期：2013-02-01 00:00:00

  • Further evidence for the association between LRP8 and schizophrenia.

    abstract：:Previous studies (including genome-wide association study (GWAS) and candidate gene studies) have revealed the important roles of genetic risk factors in schizophrenia, and RELN has been identified as a risk gene for this illness. We recently found that the low-density lipoprotein receptor-related protein 8 (LRP8), a ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.05.002

    authors： Xiao X,Yu H,Li J,Wang L,Li L,Chang H,Zhang D,Yue W,Li M

    更新日期：2020-01-01 00:00:00