Abstract:
:The Framingham and other epidemiological studies have shown HDL and triglyceride to be inversely correlated. An independent relationship between HDL cholesterol and CAD was observed in other studies and also suggested by interventional trials. Decreased HDL-C and mildly elevated LDL-C are common in patients with coronary artery disease. Identification of receptors involved in the metabolism of HDL has been the subject of intensive research. The HDL particle may be recognized by different receptors in various tissues. Niacin and fibrate have a remarkable effect on the reduction of triglyceride and elevation of HDL, while their LDL lowering effect is moderate. Statins are effective and safe drugs for CHD, and exert beneficial effects across the lipoprotein profile. Therefore, the effects of statins on HDL-C may contribute to reductions in coronary events.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Paragh G,Harangi Msubject
Has Abstractpub_date
2001-01-21 00:00:00pages
121-6issue
3eissn
0030-6002issn
1788-6120journal_volume
142pub_type
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