[Primary liver cancer following prolonged use of contraceptive drugs].

Abstract:

:The authors have observed cancer of the liver without cirrhosis, in a woman aged 32. The disease manifested itself immediately after childbirth and provoked death 3 months after the delivery. Before her pregnancy, the patient had been taking Infecundin for 7 years. The pregnancy went to term without any difficulty. The symptoms appeared after the delivery: abdominal pain, more and more frequent spasms in the right side, increasing progressively in intensity. The body temperature rose to 38 degrees Celsius. The patient lost some weight and became weaker and weaker every day. A malignant tumor of the liver was discovered. A laparotomy was performed: both lobes of the liver were of considerable size with swollen, grey-white growths the size of cherries. The patient died 3 months after the appearance of the 1st symptoms. A study of the literature published on this subject suggests the possibility of a connection between the malignant tumors in the liver and the prolonged use of oral contraceptives combined with the hormonal changes occuring during pregnancy.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Balázs M,Gergely R,Winkler G

subject

Has Abstract

pub_date

1977-02-06 00:00:00

pages

334-6

issue

6

eissn

0030-6002

issn

1788-6120

journal_volume

118

pub_type

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