Abstract:
:The authors present a case report and review the literature on Hashimoto encephalopathy. The onset of the disease may be marked by focal and then progressively generalized seizures or other neurological symptoms, but a cognitive decline or various psychiatric symptoms may also emerge. High levels of anti-thyroid peroxidase antibodies and/or anti-thyroglobulin antibodies are present in the serum. Corticosteroid treatment usually results in an improvement of symptoms. The syndrome is frequently overlooked and, therefore, the authors strongly recommend testing serum thyroid autoantibodies in cases with encephalopathy of unknown origin independently on the presence of thyroid disease in the patient or family history. The importance of long-term immunosuppressive treatment should also be stressed. :A szerzők egy beteg kórlefolyásának ismertetése kapcsán taglalják a Hashimoto-encephalopathia irodalmát. A betegség kezdődhet fokális indulású, majd generalizálódó epilepsziás görcsrohamokkal vagy más góctünetekkel, de jelentkezhet kognitív hanyatlással vagy színes pszichiátriai képpel is. A thyreoidea-peroxidáz ellenes és/vagy a thyreoglobulin-ellenes antitestek szintje emelkedett a szérumban. Kortikoszteroidra általában jó terápiás válasz észlelhető. Sok esetben nem ismerik fel a kórképet. Ezért ismeretlen okú encephalopathia tünetei mellett pozitív személyes vagy családi pajzsmirigy-anamnézis esetén (vagy még annak hiányában is) célszerű a pajzsmirigyellenes autoantitestek meghatározása. A szerzők kiemelik a hosszú távú immunoszuppresszív kezelés jelentőségét. Orv. Hetil., 2013, 154, 1312–1316.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Pocsay G,Gazdag A,Engelhardt J,Szaniszló I,Szolnoki Z,Forczek G,Mikló Ldoi
10.1556/OH.2013.29684subject
Has Abstractpub_date
2013-08-18 00:00:00pages
1312-6issue
33eissn
0030-6002issn
1788-6120pii
V5811KN351NUV641journal_volume
154pub_type
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