Possible interaction between cyclosporine and glibenclamide in posttransplant diabetic patients.

Abstract:

:The possible occurrence of a kinetic interaction between cyclosporine A and glibenclamide was assessed by reviewing data of six posttransplant diabetic patients who received the two drugs concurrently. Coadministration of the two drugs resulted in a 57% increase in the steady-state plasma cyclosporine levels despite normal hepatic and renal functions in the patients. This elevation in cyclosporine level is possibly due to an interaction between the two drugs resulting from an inhibition of CYP3A4-mediated metabolism of cyclosporine by glibenclamide. This observation calls for a closer monitoring of cyclosporine plasma levels during concomitant administration of these two drugs in this group of patients.

journal_name

Ther Drug Monit

authors

Islam SI,Masuda QN,Bolaji OO,Shaheen FM,Sheikh IA

doi

10.1097/00007691-199610000-00017

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

624-6

issue

5

eissn

0163-4356

issn

1536-3694

journal_volume

18

pub_type

杂志文章
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    更新日期:2014-02-01 00:00:00

  • Possible interaction between acyclovir and antiepileptic treatment.

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    doi:

    authors: Parmeggiani A,Riva R,Posar A,Rossi PG

    更新日期:1995-06-01 00:00:00

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    更新日期:1983-01-01 00:00:00

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    journal_title:Therapeutic drug monitoring

    pub_type: 杂志文章

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    authors: Laurino JP,McKay J,Fischberg E,Schwenzer K,Kaufman R

    更新日期:1994-06-01 00:00:00

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    journal_title:Therapeutic drug monitoring

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    更新日期:2006-04-01 00:00:00

  • Lack of significant correlation between circadian profiles of valproic acid serum levels and epileptiform electroencephalographic activity.

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    pub_type: 杂志文章

    doi:10.1097/00007691-198406000-00008

    authors: Burr W,Froescher W,Hoffmann F,Stefan H

    更新日期:1984-01-01 00:00:00

  • Effect of antacids on phenytoin bioavailability.

    abstract::Eight subjects were studied in a randomized crossover design to determine the effect of aluminum-magnesium hydroxide (AMH), calcium carbonate (CC), and aluminum hydroxide-magnesium trisilicate (AHMT) on the bioavailability of a single, 600-mg dose of phenytoin administered orally. Each subject received phenytoin alone...

    journal_title:Therapeutic drug monitoring

    pub_type: 临床试验,杂志文章,随机对照试验

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    authors: Carter BL,Garnett WR,Pellock JM,Stratton MA,Howell JR

    更新日期:1981-01-01 00:00:00

  • Impact of Laboratory Practices on Interlaboratory Variability in Therapeutic Drug Monitoring of Immunosuppressive Drugs.

    abstract::The immunosuppressants cyclosporine, tacrolimus, sirolimus, everolimus, and probably also mycophenolic acid require therapeutic drug monitoring (TDM)-guided dosing to ensure that blood concentrations are kept within the target range in transplant patients. Reliable, accurate, and precise test methods are therefore ess...

    journal_title:Therapeutic drug monitoring

    pub_type: 杂志文章

    doi:10.1097/FTD.0000000000000205

    authors: Christians U,Vinks AA,Langman LJ,Clarke W,Wallemacq P,van Gelder T,Renjen V,Marquet P,Meyer EJ

    更新日期:2015-12-01 00:00:00

  • Quality Assessment of Dried Blood Spots from Patients With Tuberculosis from 4 Countries.

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    pub_type: 杂志文章

    doi:10.1097/FTD.0000000000000659

    authors: Zuur MA,Veenhof H,Aleksa A,Vanʼt Boveneind-Vrubleuskaya N,Darmawan E,Hasnain MG,Heysell SK,Jongedijk EM,Koster RA,Magis-Escurra C,Martinez N,Molinas G,Mondal D,Mulyani UA,Perwitasari DA,Tsivunchyk A,Touw DJ,Alffenaar JC

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  • Risperidone and Venlafaxine Metabolic Ratios Strongly Predict a CYP2D6 Poor Metabolizing Genotype.

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    pub_type: 杂志文章

    doi:10.1097/FTD.0000000000000251

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    更新日期:2016-02-01 00:00:00

  • Cyclosporin A trough levels correlate with serum lipoproteins and apolipoproteins: implications for therapeutic drug monitoring of cyclosporin A.

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    journal_title:Therapeutic drug monitoring

    pub_type: 杂志文章

    doi:10.1097/00007691-199704000-00004

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    更新日期:1997-04-01 00:00:00

  • A sensitive gas chromatographic assay for amitriptyline and nortriptyline in plasma.

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    journal_title:Therapeutic drug monitoring

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    journal_title:Therapeutic drug monitoring

    pub_type: 杂志文章

    doi:10.1097/FTD.0b013e3182804c9b

    authors: Hartmann B,He X,Keller F,Fischereder M,Guba M,Schmid H

    更新日期:2013-04-01 00:00:00

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    doi:10.1097/00007691-199906000-00017

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    更新日期:1999-06-01 00:00:00

  • Accurately Achieving Target Busulfan Exposure in Children and Adolescents With Very Limited Sampling and the BestDose Software.

    abstract:BACKGROUND:Busulfan dose adjustment is routinely guided by plasma concentration monitoring using 4-9 blood samples per dose adjustment, but a pharmacometric Bayesian approach could reduce this sample burden. METHODS:The authors developed a nonparametric population model with Pmetrics. They used it to simulate optimal ...

    journal_title:Therapeutic drug monitoring

    pub_type: 杂志文章

    doi:10.1097/FTD.0000000000000276

    authors: Neely M,Philippe M,Rushing T,Fu X,van Guilder M,Bayard D,Schumitzky A,Bleyzac N,Goutelle S

    更新日期:2016-06-01 00:00:00

  • Multicenter quality control study of amikacin assay for monitoring once-daily dosing regimens. International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Cancer.

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    journal_title:Therapeutic drug monitoring

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/00007691-199504000-00005

    authors: Blaser J,König C,Fatio R,Follath F,Cometta A,Glauser M

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    journal_title:Therapeutic drug monitoring

    pub_type: 杂志文章

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    authors: Andrés I,López R,Pou L,Piñol F,Pascual C

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    journal_title:Therapeutic drug monitoring

    pub_type: 杂志文章

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    更新日期:1993-08-01 00:00:00

  • Quantification of immunosuppression by flow cytometry in stable renal transplant recipients.

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    pub_type: 杂志文章

    doi:10.1097/00007691-200302000-00003

    authors: Stalder M,Bîrsan T,Holm B,Haririfar M,Scandling J,Morris RE

    更新日期:2003-02-01 00:00:00

  • Evaluation of pharmacokinetic methods used to estimate caffeine clearance and comparison with a Bayesian forecasting method.

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    pub_type: 杂志文章

    doi:10.1097/00007691-199802000-00015

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    更新日期:1998-02-01 00:00:00

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    更新日期:2001-08-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2019-10-01 00:00:00

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    abstract::Phenytoin is an anticonvulsant that requires therapeutic drug monitoring. Recently, Bayer HealthCare, Diagnostics Division released a turbidimetric immunoassay of phenytoin on the ADVIA 1650 analyzer. We evaluated the analytic performance of this assay by comparing values obtained in 52 patients receiving Phenytoin us...

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    pub_type: 杂志文章

    doi:10.1097/01.ftd.0000164315.13825.dd

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    更新日期:2005-06-01 00:00:00

  • Plasma concentrations of dothiepin and its metabolites are not correlated with clinical efficacy in major depressive illness.

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    pub_type: 杂志文章

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    更新日期:2003-02-01 00:00:00

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