Multicentre study of the in vitro activity of cefepime, a broad-spectrum cephalosporin, compared to other broad-spectrum agents.

abstract：AIMS:Pancreatic endocrine tumours (PET) containing ductules are an uncommon histological variant. Considerable conjecture surrounds the origin and histogenesis of the ductules. Opinions range from the ductules being an inherent part of the tumour, to others who feel they are merely entrapped. A study of 21 cases of thi...

journal_title：Pathology

authors： Chetty R,Serra S,Asa SL,Volkan Adsay N

更新日期：2006-02-01 00:00:00

abstract：:Lymphomatous involvement of skin usually manifests as plaques, maculopapules, papulonodules, tumorous masses or ulcerated eruptions. We report an unusual case in which the cutaneous relapse of nasal T-cell lymphoma clinically mimicked erythema multiforme by the abrupt onset of lesions and the presence of targetoid and...

journal_title：Pathology

authors： Chan JK,Sin VC,Ng CS,Lau WH

更新日期：1989-07-01 00:00:00

abstract：:Birth defects of the brain result from malformation and disruptions. They remain an important cause of childhood morbidity and mortality. Effective treatments are scarce and prevention strategies limited. As aetiological screening is costly and uncertain, genetic counselling remains empirical in most cases. A patholog...

journal_title：Pathology

authors： Encha-Razavi F,Gonzalès M,Laquerrière A,Martinovic J,Sinico M,Allias F,Bonnière M,Esculpavit C,Gerard M,Attié-Bitach T,Vekemans M

更新日期：2008-02-01 00:00:00

abstract：:We report a case of multiple hepatic abscesses due to Yersinia enterocolitica in a 58 yr old male. This case is typical of the other 39 cases reported in the literature in that the patient had alcoholism, malnutrition, iron overload and a subsequently diagnosed malignancy. Ultrasound showed multiple hypoechoic areas i...

journal_title：Pathology

authors： Strungs I,Farrell DJ,Matar LD,Dekker L,Franz RJ

更新日期：1995-10-01 00:00:00

abstract：:In contrast to Caucasians, Japanese people have a relatively high incidence of malignant melanoma in the oral cavity and volar-subungual skin. The classification of oral melanoma has not been established. We report 7 new cases of oral melanoma, with a review of 36 cases, published in Japan, between 1970 and 1984. Most...

journal_title：Pathology

authors： Umeda M,Mishima Y,Teranobu O,Nakanishi K,Shimada K

更新日期：1988-07-01 00:00:00

abstract：:A sequential study has been made of the ultrastructure of local renal graft-versus-host reactions produced in cyclophosphamide-pretreated rats by injection of either allogeneic or xenogeneic (mouse) spleen cells beneath the renal capsule. Early in the reaction, immunoblasts were seen between the outer cortical tubules...

journal_title：Pathology

authors： Davies DJ,Conway MS

更新日期：1975-10-01 00:00:00

abstract：:Results are presented of a study comparing cerbB2 (neu or Her2) expression as assessed immunohistochemically in breast neoplasia using a panel of 6 commercially available antibodies. The antibodies were examined utilizing conventional formalin fixed paraffin embedded tissue, and compared with molecular analysis of gen...

journal_title：Pathology

authors： Busmanis I,Feleppa F,Jones A,McGrath KM,Reed R,Collins J,Russell I,Begley CG

更新日期：1994-07-01 00:00:00

abstract：:Glomeruli from 48 cases of glomerulonephritis (Gn) were isolated and studied by means of the scanning electron microscope (SEM). Overall glomerular loss due to processing was 2.4%. SEM of these isolated glomeruli showed good preservation of glomerular structure. Changes of the podocyte cell body and its foot processes...

journal_title：Pathology

authors： Ng WL,Chan KW,Ma L

更新日期：1983-04-01 00:00:00

abstract：:This report describes the case of a 63 yr old male with an enlarging lesion on the left cheek. Excision biopsy showed a squamous cell carcinoma arising from an eccrine hidrocystoma. The eccrine hidrocystoma showed foci of squamous metaplasia and the sequence of squamous metaplasia complicated by squamous carcinoma is ...

journal_title：Pathology

authors： Theocharous C,Jaworski RC

更新日期：1993-04-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate the role of Serpin B3/B4 in advanced idiopathic pulmonary fibrosis (IPF) patients, mainly focusing on epithelial proliferation. METHODS:Lungs from 48 IPF patients (including cases with cancer or high-grade epithelial dysplasia) were studied and compared with other diffuse pare...

journal_title：Pathology

authors： Calabrese F,Lunardi F,Balestro E,Marulli G,Perissinotto E,Loy M,Nannini N,Valente M,Saetta M,Agostini C,Rea F

更新日期：2012-04-01 00:00:00

abstract：:Malignant pleural mesothelioma (MPM) is often associated with a poor prognosis and options for the treatment of this disease are few. To date, the important role of the immune microenvironment in modifying the disease natural history is well established. The programmed cell death pathway (PD-1/PD-L1) limits the T lymp...

journal_title：Pathology

authors： Rrapaj E,Giacometti L,Spina P,Salvo M,Baselli GA,Veggiani C,Rena O,Trisolini E,Boldorini RL

更新日期：2020-11-30 00:00:00

abstract：:Semen analysis is the most important laboratory investigation for men when assessing the infertile couple. Advances in in vitro fertilisation (IVF) techniques, particularly intracytoplasmic sperm injection (ICSI) involving the direct injection of a single spermatozoon into an egg, have not diminished the role of semen...

journal_title：Pathology

authors： McLachlan RI,Baker HW,Clarke GN,Harrison KL,Matson PL,Holden CA,de Kretser DM,Andrology Australia Australian Centre of Excellence in Male Reproductive Health.,Fertility Society of Australia Scientists in Reproductive Technology Subcommit

更新日期：2003-02-01 00:00:00

abstract：AIMS:Twenty-six cases of granulomatous mastitis were examined to determine the common histological and clinical features and the possible association with micro-organisms. METHODS:A retrospective review of the clinical and histological features of these cases was undertaken, including granuloma, inflammatory cell infi...

journal_title：Pathology

authors： Tse GM,Poon CS,Ramachandram K,Ma TK,Pang LM,Law BK,Chu WC,Tang AP,Cheung HS

更新日期：2004-06-01 00:00:00

abstract：:Tumor cell-platelet interactions have been shown to be involved in the process of metastasis. This study characterizes the aggregation of washed platelets induced by the human uterine carcinosarcoma Colo 526. Ultrastructural studies revealed a two-stage process in which the earliest events were the adhesion and degran...

journal_title：Pathology

authors： Bradley CJ,Dauer RJ,Thurlow PJ,Connellan JM

更新日期：1997-05-01 00:00:00

abstract：:We evaluated an immunoradiometric assay for serum TSH (IRMA-TSH) and compared it with established indices of thyroid function in 208 patients with either frank thyroid disease, conditions of abnormal thyroxine protein binding, or conditions which are known to produce discordant thyroid results, viz. pregnancy or estro...

journal_title：Pathology

authors： McLellan GH,Riley WJ,Summers MB,Sudholz P,Hickman PE

更新日期：1987-07-01 00:00:00

abstract：:Malignant gastrointestinal neuroectodermal tumour (GNET) is a recently characterised rare and aggressive tumour that typically arises in association with the small intestine of adults. We present a novel case of this entity and expand the spectrum of its reported morphological features. The patient was a 5-year-old fe...

journal_title：Pathology

authors： Allanson BM,Weber MA,Jackett LA,Chan C,Lau L,Ziegler DS,Warby M,Mayoh C,Cowley MJ,Tucker KM,Long GV,Maher A,Anazodo A,Scolyer RA

更新日期：2018-10-01 00:00:00

abstract：:Multiplex immunofluorescence (mIF) allows simultaneous antibody-based detection and quantification of the expression of up to six markers, plus a nuclear counterstain, on a single tissue section. Recent studies have shown the potential for mIF to advance our understanding of complex disease processes, including cancer...

journal_title：Pathology

authors： Lim JCT,Yeong JPS,Lim CJ,Ong CCH,Wong SC,Chew VSP,Ahmed SS,Tan PH,Iqbal J

更新日期：2018-04-01 00:00:00

abstract：:The mitogenic and chemotactic potency of platelet-derived growth factor (PDGF) has linked this polypeptide to the pathogenesis of several disease states including atherosclerosis and neoplasia. We have reviewed the recent literature on aspects relating to the structure, distribution and biology of PDGF and its high-af...

journal_title：Pathology

authors： Khachigian LM,Chesterman CN

更新日期：1992-10-01 00:00:00

abstract：:Ethanol in blood was assayed by 2 currently available procedures: a commercial kit enzymatic assay and a gas chromatographic procedure. Both methods were performed with commercially available materials and equipment. Results by the 2 procedures agreed well. For the 192 specimens studied, the correlation coefficient wa...

journal_title：Pathology

authors： Taylor GF,Turrill GH,Carter NG

更新日期：1984-04-01 00:00:00

abstract：:A new mucin antigen was detected in a mucinous cystadenoma of human ovary. An antiserum produced in rabbits against the crude cyst fluid, following appropriate absorptions, showed immunoreactivity exclusively with tumour epithelium, particularly endocervical type epithelium. The antigen responsible for the immunoreact...

journal_title：Pathology

authors： Ma J,Handley CJ,de Boer WG

更新日期：1983-10-01 00:00:00

abstract：:The case is reported of a woman aged 60 yrs who presented with systemic symptoms and who was found to have proteinuria of 3.5 g per day. A renal biopsy revealed numerous neoplastic cells filling many of the glomerular capillary lumina. Immunoperoxidase stains revealed that the phenotype of the malignant cells was LCA+...

journal_title：Pathology

authors： Axelsen RA,Laird PP,Horn M

更新日期：1991-07-01 00:00:00

abstract：:Perhexiline maleate is a potent anti-anginal drug which may cause alcoholic-type hepatitis and cirrhosis. We report a case of a patient who developed cirrhosis on a relatively low dose within 16 mth. ...

journal_title：Pathology

authors： Pieterse AS,Rowland R,Dunn D

更新日期：1983-04-01 00:00:00

abstract：:Use of cellular products for therapeutic purposes has predominantly been unregulated in Australia until recently. Transplant of haemopoietic progenitor cells (HPC) for bone marrow regeneration is now a routine treatment for many disorders with an established mechanism of facility accreditation. However, other cellular...

journal_title：Pathology

authors： Trickett AE,Wall DM

更新日期：2011-10-01 00:00:00

abstract：:Granulomatous (lobular) mastitis is a rare inflammatory breast disease affecting parous reproductive-aged women. Once considered idiopathic, there is growing evidence of an association with corynebacteria infection, especially in the setting of a distinct histological pattern termed cystic neutrophilic granulomatous m...

journal_title：Pathology

authors： Johnstone KJ,Robson J,Cherian SG,Wan Sai Cheong J,Kerr K,Bligh JF

更新日期：2017-06-01 00:00:00

abstract：:Since 1967 the Royal College of Pathologists of Australasia has been providing an external quality assurance programme in microbiology. The number of participants has risen from 70 to 222, and the samples distributed for investigation have increased in quantity, now totalling 35-40 per annum, and in variety, so that m...

journal_title：Pathology

authors： Ackerman VP,Pritchard RC

更新日期：1984-07-01 00:00:00

abstract：:A review of the morphological and metabolic interactions between hepatocytes, the various sinusoidal cells and sinusoidal blood is presented. This field of investigation is rapidly expanding, with widespread implications in the regulation of physiological processes and diseases in the liver and other organs. Although ...

journal_title：Pathology

authors： Fraser R,Day WA,Fernando NS

更新日期：1986-01-01 00:00:00

abstract：:Human glomerular basement membrane (GBM) emulsified in Freund's complete adjuvant was injected into 16 Holtzman rats. Eleven (69%) of them subsequently developed glomerulonephritis. This disease was characterized by glomerular changes which included focal lobular hypercellularity due to localized hyperplasia of intrac...

journal_title：Pathology

authors： McCausland IP,Herdson PB,Gavin JB

更新日期：1976-04-01 00:00:00

abstract：:A diptheria immunoglobulin has been prepared from selected blood donations to the Australian Red Cross Transfusion Services. A dose of 250 I.U. has been demonstrated to raise the titre of diptheria antitoxin in non-immune subjects to protective levels within 24 h, and these levels remain protective for at least 5 wk. ...

journal_title：Pathology

authors： Hartman LJ

更新日期：1979-07-01 00:00:00

abstract：AIM:To determine whether the common respiratory pathogen, Chlamydia pneumoniae, was associated with atherosclerotic plaques in Australian subjects. METHODS:A total of 29 coronary atherosclerotic lesions and 18 normal coronary arterial samples were tested for the presence of C. pneumoniae by PCR and immunofluorescence ...

journal_title：Pathology

authors： Cochrane M,Kalle WH,Roffey P,Moriarty HT

更新日期：2002-06-01 00:00:00

abstract：AIMS AND METHODS:During colorectal carcinogenesis, transforming growth factor beta 1 (TGF-beta1) undergoes a functional change from suppression of cancer cell proliferation to inhibition of T cell mediated anti-cancer immunity. We aimed to evaluate relations among TGF-beta1 and cancer cell survival factors hypoxia indu...

journal_title：Pathology

authors： Sulkowska M,Wincewicz A,Sulkowski S,Koda M,Kanczuga-Koda L

更新日期：2009-01-01 00:00:00