Inside-out versus standard artery graft to repair a sensory nerve in rats.

Abstract:

:It is known that a vein graft provides a good microenvironment for axon regeneration in motor peripheral nerves, but the use of artery graft for regeneration of sensory nerves is controversial. We sectioned the saphenous nerve and repaired it by using heterologous inside-out and standard artery graft techniques in rats. After 4, 12, and 20 weeks, the graft and the distal stump were observed under electron microscopy. In each period studied, the pattern, diameters, and thickness of the myelin sheaths of the regenerated axons were measured in the graft and distal stump. There was capillary invasion in both the graft and distal stump, especially in the inside-out artery graft group. Regenerated nerve fibers were prominent in both heterologous artery grafts 4 weeks after the surgical procedures. Conversely, in the distal stump, regenerated nerve fibers were observed only after 12 weeks. In both the inside-out artery graft and standard artery graft, no statistical difference in the diameters and thickness of the myelinated fibers after 20 weeks was observed.

journal_name

Microsurgery

journal_title

Microsurgery

authors

Rodrigues Ade C,Silva MD

doi

10.1002/micr.1017

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

102-7

issue

3

eissn

0738-1085

issn

1098-2752

pii

10.1002/micr.1017

journal_volume

21

pub_type

杂志文章
  • Do leukocytes contribute to impaired microvascular tissue perfusion after arterial repair?

    abstract::Impaired capillary perfusion may result in flap failure. Platelet emboli, polymorphonuclear leukocytes (PMNs), and/or vasospasm have been identified as possible causes. This study investigates the role of PMNs in causing impaired capillary perfusion in a free flap model. PMN concentrations were depleted using antineut...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/(sici)1098-2752(1998)18:1<23::aid-micr6>3.

    authors: Peter FW,Schuschke DA,Wang WZ,Anderson GL,Franken RJ,Pierangeli S,Barker JH

    更新日期:1998-01-01 00:00:00

  • Effect of hyperbaric oxygen on pedicle flaps with compromised circulation.

    abstract::The effect of hyperbaric oxygen (HBO) on the survival rate of experimental rat pedicle island flaps with arterial, venous, and combined arteriovenous insufficiency was evaluated. Forty male Wistar rats with pedicle island flaps were divided into four groups with different types of vascular status. Another 40 male Wist...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.22004

    authors: Ulkür E,Yüksel F,Açikel C,Celiköz B

    更新日期:2002-01-01 00:00:00

  • Free vascularized fibular graft for treatment of pathological femoral neck fracture and osteonecrosis of the femoral head: a case report with a long-term follow-up.

    abstract::We present a case of a 34-year-old white female patient who, 13 years ago, sustained a pathological intracapsular femoral neck fracture on a pre-existing aneurysmal bone cyst. Three months later radiographic and magnetic resonance imaging evaluation revealed both femoral neck fracture and stage IV osteonecrosis of the...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20598

    authors: Beris AE,Lykissas MG,Payatakes A,Kontogeorgakos VA,Mavrodontidis A,Korompilias AV

    更新日期:2009-01-01 00:00:00

  • Healing of a severe microarterial trauma: an experimental study.

    abstract::A severe microarterial trauma (arteriotomy/intimectomy) was introduced to the central arteries of rabbit ears. Twenty-one patent vessels, 3 at each interval of 2 hours, 1, 3, 7, 14, 30, and 90 days after reperfusion were taken for light and scanning electron microscopy studies. These vessels remained patent at all tim...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920150208

    authors: Zhang B,Wieslander JB

    更新日期:1994-01-01 00:00:00

  • Regeneration across cold preserved peripheral nerve allografts.

    abstract::The feasibility of peripheral nerve allograft pretreatment utilizing cold storage (5 degrees C in the University of Wisconsin Cold Storage Solution) or freeze-thawing to prevent rejection was investigated. Regeneration across cold-stored (3 or 5 weeks) or freeze-thawed (FT), 3.0-cm sciatic nerve allografts were compar...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/(sici)1098-2752(1999)19:3<115::aid-micr1>3

    authors: Evans PJ,MacKinnon SE,Midha R,Wade JA,Hunter DA,Nakao Y,Hare GM

    更新日期:1999-01-01 00:00:00

  • Medialis pedis flap for reconstruction of weight bearing heel.

    abstract:BACKGROUND:Among the various flaps available for the reconstruction of the heel, a medial plantar flap has been widely accepted as the most ideal. This flap, however, involves the medial plantar nerve and its cutaneous branches, which may lead to postoperative hyperesthesia and dual sensation. The purpose of this repor...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.30198

    authors: Park JS,Lee JH,Lee JS,Baek JH

    更新日期:2017-10-01 00:00:00

  • Successful microvascular replantation of a completely amputated ear.

    abstract::A case of successful microvascular replantation of a traumatically amputated ear is presented. The postoperative course was complicated by venous thrombosis requiring the use of medicinal leeches and systemic heparinization for salvage. This is the tenth successful microvascular ear replantation reported in the litera...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920140505

    authors: Rapaport DP,Breitbart AS,Karp NS,Siebert JW

    更新日期:1993-01-01 00:00:00

  • Pectoralis major turnover flap based on thoracoacromial vessels for sternal dehiscence.

    abstract:BACKGROUND:Reconstruction of long and deep sternal defects has been challenging. The pectoralis major can be used in the conventional turnover method that requires the internal thoracic vessel. We developed a new turnover pectoralis major flap based on thoracoacromial vessels. The purpose of this report is to present r...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.30509

    authors: Goishi K,Harada H,Keyama T,Tsuda T,Hashimoto I

    更新日期:2020-02-01 00:00:00

  • Improved reflow and viability in reperfused ischemic rat island groin flaps using dexamethasone.

    abstract::Reperfusion injury and the no-reflow phenomenon are manifestations of a complex series of events that culminate in an acute inflammatory reaction within reperfused tissue. Antiinflammatory therapy attenuates ischemia-reperfusion injury. The purpose of this study is to evaluate the effects of dexamethasone on blood flo...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920160208

    authors: Dolan RW,Kerr DC,Arena S

    更新日期:1995-01-01 00:00:00

  • Morphometric changes in free neurovascular latissimus dorsi flaps: an experimental study.

    abstract::This study was designed to investigate regeneration of reinnervated, free transplanted muscles. We used a rat model, consisting of eight rats per group, in which the latissimus dorsi muscle was transplanted orthotopically and then harvested and evaluated after 2 and 12 weeks. Age-matched control animals were used to o...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920161205

    authors: Becker MH,Lassner F,Dagtekin FZ,Walter GF,Berger A

    更新日期:1995-01-01 00:00:00

  • Secondary ischemic tolerance improved by administration of L-NAME in rat flaps.

    abstract::Nitric oxide (NO) under basal conditions is an important regulator of vascular tone. Under ischemic conditions, however, NO can combine with superoxide anion to produce the damaging hydroxyl free radical. The current project observes the effect of inhibiting NO production (L-Nitro-amino-methyl-arginine, L-NAME) on fla...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/(SICI)1098-2752(1996)17:8<425::AID-MICR1>3

    authors: Knox LK,Angel MF,Gamper T,Amiss LR,Morgan RF

    更新日期:1996-01-01 00:00:00

  • Late transplantation period of mice fetal intestine grafts: morphometric aspects.

    abstract::Morphometric evaluation of the fetal intestinal graft in the late post-transplant period was done by using C57BL/6 mice. Under anesthesia, after hysterotomy, a transversal laparotomy was done in the fetus to harvest all intestines. Grafts, cleaned from its mesentery, and divided were transplanted into the preperitoneu...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20356

    authors: Saldanha De Almeida CE,Artigiani R,Ferreira De Oliveira K,Riboli Navarro PG,Montero EF

    更新日期:2007-01-01 00:00:00

  • A new type of magnification system in free microvascular tissue transfer: Varioscope M5.

    abstract::Free microvascular tissue transfers have become today a key instrument for the surgical treatment of wide loss of tissue. These procedures can provide definitive treatment in a single operation but they are expensive and require specialized practitioners. The operating microscope traditionally has provided this requir...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20399

    authors: Chiummariello S,Fioramonti P,Menichini G,Scuderi N,Alfano C

    更新日期:2007-01-01 00:00:00

  • Supermicrosurgical lymphaticovenular anastomosis and lymphaticovenous implantation for treatment of unilateral lower extremity lymphedema.

    abstract::Recent supermicrosurgical techniques have developed the possibility for vascular anastomosis of smaller vessels and it is now safe and sound to perform precise anastomoses between lymphatics and venules. Reported here is the 2 years experience on supermicrosurgical lymphaticovenular anastomosis and/or lymphaticovenous...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20665

    authors: Demirtas Y,Ozturk N,Yapici O,Topalan M

    更新日期:2009-01-01 00:00:00

  • Experimental study on the behavior of a transplanted vascular pedicle.

    abstract::The transparent chamber technique of the hamster cheek pouch was utilized to observe the behavior of a transplanted vascular pedicle within a relatively adverse environment. Observations included direct visualization with intravital microscopy, histology, scanning electron microscopy, and alkaline phosphatase staining...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920100307

    authors: Hung LK,Leung PC,Cheng GL

    更新日期:1989-01-01 00:00:00

  • The treatment of composite defect of bone and soft tissues with a combined latissimus dorsi and serratus anterior and rib free flap.

    abstract:BACKGROUND:Composite defects of bone and soft tissues represent a reconstructive challenge. Several techniques have been described in the medical literature; however, extensive composite defects should be reconstructed with microvascular free tissue transfer. The purpose of this report is to present the use of a compos...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.22067

    authors: Trignano E,Fallico N,Nitto A,Chen HC

    更新日期:2013-03-01 00:00:00

  • Technique of total hepatectomy in the rat.

    abstract::We report a novel one-stage technique of total hepatectomy in the rat, in which the liver is replaced by an autologous prosthesis. This prosthesis is obtained from a donor rat, and consists of the subhepatic vena cava and the left renal vein harvested en block. This graft is sutured with the subdiaphragmatic cava and ...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920160711

    authors: Lorenzo M,Angrisani L,Ventriglia R,Ismail T,Tesauro B

    更新日期:1995-01-01 00:00:00

  • Nerve growth factor combined with an epineural conduit for bridging a short nerve gap (10 mm). A study in rabbits.

    abstract::The purpose of this study was to evaluate the effect of direct administration of nerve growth factor (NGF) into an epineural conduit across a short nerve gap (10 mm) in a rabbit sciatic nerve model. The animals were divided into two groups. In group 1, n = 6, a 10-mm defect was created in the sciatic nerve and bridged...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20925

    authors: Barmpitsioti A,Konofaos P,Ignatiadis I,Papalois A,Zoubos AB,Soucacos PN

    更新日期:2011-10-01 00:00:00

  • Intrinsic haemangioma of the median nerve: report of a case and review of the literature.

    abstract::Intrinsic haemangioma of the median nerve is an extremely rare tumor that represents a challenge to diagnose and treat. Only a few cases have been reported in the literature. We present a 10-year-old girl who was diagnosed having an intrinsic haemangioma of the median nerve and treated with total surgical resection of...

    journal_title:Microsurgery

    pub_type: 杂志文章,评审

    doi:10.1002/micr.20456

    authors: Vekris MD,Stafilas KS,Zacharis KX,Xenakis TA,Soucacos PN,Beris AE

    更新日期:2008-01-01 00:00:00

  • Reconstruction of mandibular defects using the scapular tip free flap.

    abstract:PURPOSE:Purpose of the article is to present the use of the scapular tip free flap (STFF) for the reconstruction of oromandibular defects. PATIENTS:Eleven patients who underwent oromandibular reconstruction with STFF were retrospectively evaluated with regards to form and function assessing mouth opening, dietary inta...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.22285

    authors: Bianchi B,Ferri A,Ferrari S,Copelli C,Perlangeli G,Leporati M,Ferri T,Sesenna E

    更新日期:2015-02-01 00:00:00

  • Establishment of duodenojejunal bypass surgery in mice: a model designed for diabetic research.

    abstract::We have developed a mouse duodenojejunal bypass (DJB) surgical model that is for studying the effects of bariatric surgery on glucose homeostasis and has potential to impact clinical therapy of diabetes. The operation consists of using the majority of the duodenum and proximal part of the jejunum for biliopancreatic d...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20454

    authors: Liu W,Zassoko R,Mele T,Luke P,Sun H,Liu W,Garcia B,Jiang J,Wang H

    更新日期:2008-01-01 00:00:00

  • Reconstruction after resection of tumors around the knee: role of the free vascularized fibular graft.

    abstract::We present our experience with reconstruction after resection of tumors around the knee, using free vascularized fibular grafting. The study included 23 patients. The lower femur was involved in 17 cases, the upper tibia in 6. The cases included giant cell tumor of the lower femur (2 patients), giant cell tumor of the...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/1098-2752(2000)20:5<233::aid-micr4>3.0.co;

    authors: Amr SM,El-Mofty AO,Amin SN,Morsy AM,El-Malt OM,Abdel-Aal HA

    更新日期:2000-01-01 00:00:00

  • Reconstruction of peripheral nerves using acellular nerve grafts with implanted cultured Schwann cells.

    abstract::The bridging of nerve gaps is still one of the major problems in peripheral nerve surgery. The present experiment describes our attempt to engineer different biologic nerve grafts in a rat sciatic nerve model: cultured isogenic Schwann cells were implanted into 2-cm autologous acellular nerve grafts or autologous pred...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.10056

    authors: Frerichs O,Fansa H,Schicht C,Wolf G,Schneider W,Keilhoff G

    更新日期:2002-01-01 00:00:00

  • Artificial biological ligament: its making, testing, and experimental study on animals.

    abstract::By applying a novel biochemical technique using porcine tendon as the raw material with its antigen minimized, we developed an artificial biological ligament (ABL). We examined and tested its structure, mechanical properties, and biocompatibility and explored the feasibility of reconstructing the anterior cruciate lig...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20442

    authors: Wang K,Zhu L,Cai D,Zeng C,Lu H,Xu G,Guo X,Lin S,Cheng S

    更新日期:2008-01-01 00:00:00

  • Gradual graft-cell repopulation with recipient cells following vascularized bone and limb allotransplantation.

    abstract::Little is known about the fate of graft cells following vascularized bone allografting. This study was conducted to define the process of graft-cell repopulation with recipient cells. Sixty-five vascularized tibial bone and 50 limb allotransplantations were performed in rat sex-mismatched pairs. FK 506 was used for im...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20173

    authors: Muramatsu K,Kurokawa Y,Kuriyama R,Taguchi T,Bishop AT

    更新日期:2005-01-01 00:00:00

  • Microsurgical second dorsal metacarpal artery cutaneous and tenocutaneous flap for distal finger reconstruction: anatomic study and clinical application.

    abstract::In this paper, we report on the anatomical study of 34 cadaveric forearms with red latex injection and the clinical application of this study to 11 cases of microsurgical second dorsal metacarpal artery (SDMA) flaps. There were 8 cutaneous cases and 3 tenocutaneous cases using SDMA flaps for distal finger reconstructi...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20077

    authors: Yu GR,Yuan F,Chang SM,Zhang F

    更新日期:2005-01-01 00:00:00

  • Gracilis myocutaneous flap: evaluation of potential risk factors and long-term donor-site morbidity.

    abstract::This study reviewed our experience with the gracilis myocutaneous (GMC) flap, potential risk factors for flap necrosis, and long-term morbidity at the donor-site. From 1993 to 2002, 29 GMC flaps were harvested from 27 patients (pedicled n = 21 and free n = 8). The overall incidence of flap necrosis was 13.79% (partial...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20899

    authors: Papadopoulos O,Konofaos P,Georgiou P,Chrisostomidis C,Tsantoulas Z,Karypidis D,Kostakis A

    更新日期:2011-09-01 00:00:00

  • Free and island flap transfer for soft tissue defects in the hand and forearm.

    abstract::Two hundred twenty patients with soft tissue defects in the hand and forearm were treated with 226 free and island flap transfers. Reconstructed sites involved the thumb in 74 cases, the fingers in 117, the hand in 30, and the forearm in 5. Seventy-nine patients received 82 free flaps, and 141 patients received 144 is...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/(SICI)1098-2752(1996)17:3<150::AID-MICR10>

    authors: Yajima H,Tamai S,Fukui A,Ono H,Inada Y

    更新日期:1996-01-01 00:00:00

  • Replantation of amputated facial tissues with microvascular anastomosis.

    abstract::A challenge to the microsurgeon is perfecting the technique of replantation of small pieces of facial tissue, mainly because of the extremely small size of the arteries as well as a lack of suitable veins for drainage. In the past 4 years, we have had seven cases of facial amputations, which included one scalp, two na...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920150508

    authors: Jeng SF,Wei FC,Noordhoff MS

    更新日期:1994-01-01 00:00:00

  • Repairing a 35-mm-long median nerve defect with a chitosan/PGA artificial nerve graft in the human: a case study.

    abstract::We have developed a chitosan/polyglycolic acid (PGA) artificial nerve graft which was previously used for bridge implantation of dog sciatic nerves across 30-mm long defects. Here we describe a clinical trial of this graft for repairing a 35-mm-long median nerve defect at elbow of a human patient. During the 3-year fo...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20488

    authors: Fan W,Gu J,Hu W,Deng A,Ma Y,Liu J,Ding F,Gu X

    更新日期:2008-01-01 00:00:00