Serum glycated lipoproteins in type II diabetic patients with and without complications.

abstract：:We evaluated a novel assay for the measurement of 1,25 dihydroxyvitamin D (1,25 (OH)2D). Immunoextraction of 1,25(OH)2D is performed using a mini column containing a solid-phase monoclonal antibody followed by radioimmunoassay (RIA) using an 125I-labelled 1,25(OH)2D derivative tracer and Sac-cell separation. The mean ...

journal_title：Annals of clinical biochemistry

authors： Fraser WD,Durham BH,Berry JL,Mawer EB

更新日期：1997-11-01 00:00:00

abstract：:The effect of progestins on intracellular corticosteroid-binding globulin (CBG) mRNA expression in an endometrial cancer cell line (Ishikawa) was examined in an attempt to understand the biological effects of high-dose progestins in the treatment of well-differentiated uterine endometrial cancers. Oestradiol-17 beta (...

journal_title：Annals of clinical biochemistry

authors： Misao R,Nakanishi Y,Fujimoto J,Tamaya T

更新日期：1998-09-01 00:00:00

abstract：:A simple HPLC method for the determination of caffeine and theophylline in plasma is described. Separation of theobromine, paraxanthine, theophylline, beta-hydroxyethyltheophylline and caffeine is obtained using a mobile phase of 1% acetic acid/methanol (83:17, v/v) and a Waters Associates NOVA-PAK C18 column protecte...

journal_title：Annals of clinical biochemistry

authors： Pickard CE,Stewart AD,Hartley R,Lucock MD

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Oxidation of lipoproteins is thought to play a crucial role in atherogenesis. Role for triglyceride-rich lipoproteins in atherogenesis is unclear. Thus, we aimed to investigate whether cholesteryl ester hydroperoxides (CEOOH) are present in very low-density lipoproteins (VLDL) and intermediate-density lipopr...

journal_title：Annals of clinical biochemistry

authors： Shrestha R,Hui SP,Sakurai T,Yagi A,Takahashi Y,Takeda S,Jin S,Fuda H,Chiba H

更新日期：2014-11-01 00:00:00

abstract：:Fasting glycosylated haemoglobin was analysed in 535 consecutive patients having an oral 75 g glucose tolerance test for diagnostic purposes. A reference range for fasting glycosylated haemoglobin was established from patients with a non-diabetic glucose tolerance test as defined by the World Health Organisation Exper...

journal_title：Annals of clinical biochemistry

authors： Albutt EC,Nattrass M,Northam BE

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:It is now established that the bioactive lipid lysophosphatidic acid (LPA) contributes to cancer initiation, progression and metastasis, including those of prostate cancer. LPA is produced in the serum and plasma mainly by conversion from lysophospholipids through the action of lysophospholipase D (lysoPLD),...

journal_title：Annals of clinical biochemistry

authors： Nakamura K,Takeuchi T,Ohkawa R,Okubo S,Yokota H,Tozuka M,Aoki J,Arai H,Ikeda H,Ohshima N,Kitamura T,Yatomi Y

更新日期：2007-11-01 00:00:00

abstract：:We have studied 46 patients, 30 men and 16 women, with type 2 (non-insulin-dependent) diabetes in a follow-up period of 6-52 months (mean 30 months). The patients were consecutively entered in the study from the out-patient diabetic clinic. None had urinary tract infections nor proteinuria at entry. Investigations wer...

journal_title：Annals of clinical biochemistry

authors： Friis T,Pedersen LR

更新日期：1997-05-01 00:00:00

abstract：:The effect of ambient temperature on the analytical and clinical performance of a glucose meter was examined. A total of 114 venous whole blood samples were analysed for glucose by a reference method, and by a glucose meter at 21-22 degrees C, room temperatures, 26-27 degrees C and 33-34 degrees C. Glucose meter readi...

journal_title：Annals of clinical biochemistry

authors： Nawawi H,Sazali BS,Kamaruzaman BH,Yazid TN,Jemain AA,Ismail F,Khalid BA

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Abundant evidence indicate the increased levels of oxidative stress in patients with autism. Advanced glycation end products and advanced lipoxidation end products and their precursors play a major role in increased oxidative stress in numerous metabolic and neurologic diseases. Carnosine is a natural dipept...

journal_title：Annals of clinical biochemistry

authors： Ghodsi R,Kheirouri S,Nosrati R

更新日期：2019-01-01 00:00:00

abstract：:The present study was designed to re-evaluate the radioimmunoassay for desmosine in urine, which is currently used as a measure of elastin metabolism. Using ion exchange chromatography, gel filtration and affinity chromatography it was shown that at least five other compounds in hydrolysates of human urine competed fo...

journal_title：Annals of clinical biochemistry

authors： Starcher B,Scott M

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The worldwide epidemic of obesity is a major public health concern and is persuasively linked to the rising prevalence of diabetes and cardiovascular disease. Obesity is often associated with an abnormal lipoprotein profile, which may be partly negated by pioglitazone intervention, as this can influence the ...

journal_title：Annals of clinical biochemistry

authors： McEneny J,McPherson PA,McGinty A,Hull SS,McCance DR,Young IS

更新日期：2013-01-01 00:00:00

abstract：:Many contradictory results have been published on the stability of total non-esterified fatty acids in blood, plasma and serum under different storage conditions. The present study was undertaken to investigate the stability of non-esterified fatty acids, measured with an enzymatic method, in samples of EDTA-treated p...

journal_title：Annals of clinical biochemistry

authors： Menéndez LG,Fernández AL,Enguix A,Ciriza C,Amador J

更新日期：2001-05-01 00:00:00

abstract：:This paper reviews the physiology and pathology of oxygen transport from the atmosphere to the cells in critically ill patients. A thorough understanding of this allows a rational approach to monitoring and managing an hypoxic patient in the intensive care setting. ...

journal_title：Annals of clinical biochemistry

authors： Clapham MC

更新日期：1991-01-01 00:00:00

abstract：:Background For the early identification of patients at risk of developing diabetic nephropathy, we have developed an ultrasensitive immune complex transfer enzyme immunoassay to measure adiponectin in urine. Methods We developed immune complex transfer enzyme immunoassay for adiponectin and measured urinary adiponecti...

journal_title：Annals of clinical biochemistry

authors： Yamamoto M,Fujimoto Y,Hayashi S,Hashida S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:It is not possible to diagnose acute kidney injury (AKI) in early stages with traditional biomarkers. Kidney injury molecule-1 (KIM-1) is a novel biomarker promising the diagnosis of AKI in early stages. We studied whether urinary and serum KIM-1 (KIM-1 U and KIM-1 S ) concentrations were useful in predictin...

journal_title：Annals of clinical biochemistry

authors： Tekce BK,Uyeturk U,Tekce H,Uyeturk U,Aktas G,Akkaya A

更新日期：2015-01-01 00:00:00

abstract：:The effects of inhibition of inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme in guanine nucleotide de novo synthesis, on cell growth, cell viability, endogenous nucleotide concentrations and concentrations of extracellular nucleosides and bases were studied in Molt F4 human malignant lymphoblasts...

journal_title：Annals of clinical biochemistry

authors： Stet EH,De Abreu RA,Bökkerink JP,Lambooy LH,Vogels-Mentink TM,Keizer-Garritsen JJ,Trijbels FJ

更新日期：1994-03-01 00:00:00

abstract：:A total of 3227 urine specimens were analysed to investigate the applicability of a firefly luciferase assay of microbial adenosine triphosphate (ATP) for the rapid screening of bacteriuria in clinical specimens. Urine sediment, dipslide culture, and three plate cultures were also investigated in the majority of the u...

journal_title：Annals of clinical biochemistry

authors： Ruokonen A,Koskinen M,Leinonen M,Tiilikainen A,Vihko R

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:In a network of laboratories analytical variability between instruments, even of the same type, may exist for reasons beyond the control of laboratory staff. Controlling variability is a prerequisite for the application of shared reference ranges and for ensuring the transferability of patient test results. ...

journal_title：Annals of clinical biochemistry

authors： Jassam N,Lindsay C,Harrison K,Thompson D,Bosomworth MP,Barth JH

更新日期：2011-03-01 00:00:00

abstract：:Autosomal dominant hypercholesterolaemia is genetically heterogeneous, but most commonly (approximately 93%) caused by mutations in low-density lipoprotein receptor (LDLR), where the disease is known as familial hypercholesterolaemia (FH), or apolipoprotein B-100 (APOB) (approximately 5.5%), where the disease is known...

journal_title：Annals of clinical biochemistry

authors： Taylor A,Bayly G,Patel K,Yarram L,Williams M,Hamilton-Shield J,Humphries SE,Norbury G

更新日期：2010-09-01 00:00:00

abstract：:Multiple myeloma (MM) is a plasma cell dyscrasia characterized by the malignant proliferation of a plasma cell clone that produces a monoclonal immunoglobulin. Diagnosis and management of patients with monoclonal gammopathies depend on accurate identification and characterization of monoclonal proteins. We present a 6...

journal_title：Annals of clinical biochemistry

authors： Aksungar FB,Ayer M,Serteser M,Coskun A,Unsal I

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND METHODS:We report a case of insulinoma in which the diagnosis was very challenging as some of the biochemical data were consistently equivocal. In order to assess the relative reliability of the analytical tests, retrospective biochemical data on 45 other cases of histologically confirmed insulinoma were...

journal_title：Annals of clinical biochemistry

authors： Chammas NK,Teale JD,Quin JD

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The pneumatic tube system (PTS) has been implicated in inducing haemolysis. It is not known whether certain sample types are more susceptible to haemolysis than others. We assessed the level of haemolysis in commonly used sample types in the clinical biochemistry department when transported through the PTS. ...

journal_title：Annals of clinical biochemistry

authors： Sodi R,Darn SM,Stott A

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:We evaluated procalcitonin (PCT) assay in the emergency diagnosis of neonatal bacterial infection, especially in preterm infants, relative to C-reactive protein (CRP) and fibrinogen. METHODS:One hundred and twenty neonates (32 preterm), of whom 21 were infected, were tested. RESULTS:Concentrations of PCT, ...

journal_title：Annals of clinical biochemistry

authors： Guibourdenche J,Bedu A,Petzold L,Marchand M,Mariani-Kurdjian P,Hurtaud-Roux MF,Aujard Y,Porquet D

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:In the enzyme reaction for the determination of the unbound (free) bilirubin concentration by glucose oxidase and peroxidase, materials with low affinity for serum protein are reactive. The influence of these materials on the determination of serum unbound bilirubin was investigated. METHODS Serum samples fr...

journal_title：Annals of clinical biochemistry

authors： Itoh S,Kawada K,Kusaka T,Yasuda S,Okada H,Imai T,Isobe K

更新日期：2002-11-01 00:00:00

abstract：:The diagnostic performance of a new enzyme linked immunosorbent assay for the cardiac structural protein troponin T in the differential diagnosis of ischaemic cardiac damage was assessed. A well documented set of patients admitted to the coronary care unit of a district general hospital were studied. At a cutoff value...

journal_title：Annals of clinical biochemistry

authors： Collinson PO,Moseley D,Stubbs PJ,Carter GD

更新日期：1993-01-01 00:00:00

abstract：:In a 1 year prospective study we evaluated the effect of feedback of laboratory data on the requesting behaviour of physicians in general medicine. Data on within-hours and out-of-hours clinical chemistry laboratory usage and revenue expenditure for inpatients and outpatients, expressed in terms of clinical workload, ...

journal_title：Annals of clinical biochemistry

authors： Gama R,Nightingale PG,Broughton PM,Peters M,Bradby GV,Berg J,Ratcliffe JG

更新日期：1991-03-01 00:00:00

abstract：:A p-iodophenol-enhanced luminescent end-point has been incorporated into a commercially available heterogeneous competitive enzyme immunoassay for digoxin based on a horseradish peroxidase-digoxin conjugate. The luminescent end-point could be completed in less than 1 min and significantly reduced overall assay time. R...

journal_title：Annals of clinical biochemistry

authors： Coyle PM,Thorpe GH,Kricka LJ,Whitehead TP

更新日期：1986-01-01 00:00:00

abstract：:A series of experiments are described which show that second derivative spectroscopy can be used to quantify conjugated lipid dienes as markers of lipid peroxidation in heptane extracts of plasma from patients with rheumatoid arthritis, osteoarthritis, and healthy controls. Results obtained by this method gave reasona...

journal_title：Annals of clinical biochemistry

authors： Situnayake RD,Crump BJ,Zezulka AV,Davis M,McConkey B,Thurnham DI

更新日期：1990-05-01 00:00:00

abstract：:A sensitive radioimmunoassay method for sodium cromoglycate in human plasma is described. The lowest quantifiable concentration of sodium cromoglycate is 0.93 nmol/l when 0.1 ml plasma samples are analysed. Direct analysis of sodium cromoglycate concentrations in plasma samples collected up to several hours after the ...

journal_title：Annals of clinical biochemistry

authors： Brown K,Gardner JJ,Lockley WJ,Preston JR,Wilkinson DJ

更新日期：1983-01-01 00:00:00

abstract：:The current search for new treatments to combat coronary heart disease (CHD) is centred on increasing HDL-cholesterol. The failure of the CETP inhibitor torcetrapib may force a rethink. This perspective briefly reviews the antiatherosclerotic properties of HDL and ways HDL-cholesterol concentration can be raised, but ...

journal_title：Annals of clinical biochemistry

authors： Mackness B,Mackness M

更新日期：2009-01-01 00:00:00