Effect of serum from fertile and infertile patients with endometriosis on the development of mouse embryos.

Abstract:

OBJECTIVE:To evaluate the effect of serum from infertile and fertile patients with endometriosis on the development of 2-cell mouse embryos. PATIENTS:Serum was obtained from 26 infertile patients and 8 fertile patients with endometriosis. Mouse embryo development in serum samples was compared using chi 2 analysis. RESULTS:In the infertile group 23% of the embryos reached blastocyst stage, whereas 22 of the 26 samples were embryo toxic. In the fertile group significantly more embryos (45%) developed to blastocysts and only one serum samples was embryo toxic. CONCLUSION:The embryo toxicity of serum samples from patients with endometriosis is related to the infertility associated with the disease and not with the disease per se.

authors

Abu-Musa A,Takahashi K,Kitao M

doi

10.3109/00016349609054682

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

605-7

issue

7

eissn

0001-6349

issn

1600-0412

journal_volume

75

pub_type

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