Abstract:
:The subcortical dementias are a heterogeneous group of disorders in which the predominant pathological lesions occur in subcortical structures such as basal ganglia, brainstem nuclei, and the cerebellum. When the cerebral cortex is involved, the lesions are most often in the frontal lobes. These pathologic lesions are associated with cognitive changes that include bradyphrenia, personality change (apathy, depression, irritability), memory impairment, and impaired manipulation of acquired knowledge (calculation, abstraction). Aphasia, apraxia, and agnosia are commonly seen in the cortical dementias, but are absent in the subcortical dementias. Progress in research on the anatomy and connectivity of cortical-subcortical structures has led to refinement in our understanding of the cortical dementias. Despite the connectivity between the cortical and subcortical structures, patterns of cognitive impairment in subcortical dementias remain distinct.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
Darvesh S,Freedman Mdoi
10.1006/brcg.1996.0043subject
Has Abstractpub_date
1996-07-01 00:00:00pages
230-49issue
2eissn
0278-2626issn
1090-2147pii
S0278-2626(96)90043-3journal_volume
31pub_type
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pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2008.07.003
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journal_title:Brain and cognition
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1016/0278-2626(87)90133-3
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journal_title:Brain and cognition
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.bandc.2007.11.002
更新日期:2008-06-01 00:00:00
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journal_title:Brain and cognition
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doi:10.1016/j.bandc.2014.04.010
更新日期:2014-07-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/0278-2626(88)90040-1
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pub_type: 杂志文章
doi:10.1016/0278-2626(91)90065-g
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journal_title:Brain and cognition
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.bandc.2005.08.003
更新日期:2006-02-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/s0278-2626(03)00181-7
更新日期:2003-08-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2007.07.004
更新日期:2007-11-01 00:00:00
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journal_title:Brain and cognition
pub_type: 临床试验,杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1993.1060
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1995.1274
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journal_title:Brain and cognition
pub_type: 杂志文章,评审
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2009.01.009
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2012.07.003
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journal_title:Brain and cognition
pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/0278-2626(83)90006-4
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2007.07.001
更新日期:2008-03-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章,评审
doi:10.1016/j.bandc.2006.04.007
更新日期:2007-10-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2008.07.010
更新日期:2009-02-01 00:00:00