Abstract：
OBJECTIVE:To clarify the neuropsychological function in patients with Charles Bonnet Syndrome. DESIGN:Control group comparison study. SETTING:University of Chicago Hospitals. PARTICIPANTS:The neuropsychological function of 15 older adults with presenting complaints of visual hallucinations who met criteria for Charles Bonnet Syndrome (CBS) were compared with 11 demographically matched controls to determine if there was any evidence of functional brain impairment. CBS patients were screened for focal brain lesions and epileptic disturbance via MRI and EEG and also received pattern visual evoked potentials and ophthalmological examinations. MEASUREMENTS:Scores from the Wechsler Adult Intelligence Scale-Revised, Mattis Dementia Rating Scale, Wechsler Memory Scale, and the Auditory Verbal Learning Test were compared. RESULTS:Significant differences were found between the two groups on the neuropsychological measures. Moreover, 14 of 14 subjects had ocular abnormalities and six of eight had abnormal age-corrected pattern visual evoked potentials indicative of dysfunction in the visual system. CONCLUSIONS:The results of the study indicate that patients diagnosed with Charles Bonnet Syndrome evidence neuropsychological changes commonly associated with the early stages of dementia. Therefore, in patients with impaired vision, the appearance of cognitive deficits, albeit subtle, occur with the onset of visual hallucinations. We propose that isolated visual hallucinations in the older adult may be an indication of the early stages of dementia.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Pliskin NH,Kiolbasa TA,Towle VL,Pankow L,Ernest JT,Noronha A,Luchins DJdoi
10.1111/j.1532-5415.1996.tb02937.xsubject
Has Abstractpub_date
1996-09-01 00:00:00pages
1055-61issue
9eissn
0002-8614issn
1532-5415journal_volume
44pub_type
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doi：10.1111/j.1532-5415.1996.tb01870.x
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abstract：OBJECTIVES:To compare perioperative problems and outcomes of reconstructive surgery with microvascular flaps of a group of older (≥ 70) and younger adults (20-69). DESIGN:Prospective clinical cohort study. SETTING:Maxillofacial surgical unit of a university teaching hospital in Munich, Germany. PARTICIPANTS:Two hund...
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doi：10.1111/j.1532-5415.1996.tb01405.x
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