Abstract:
OBJECTIVE:To measure behaviors indicative of quality of life (QOL) in patients with Alzheimer's disease and to examine correlates of patient QOL. DESIGN:Cross-sectional investigation. SETTING:Multi-center study. PARTICIPANTS:Sample of 130 diagnosed patients. PRINCIPAL OUTCOME MEASURES: Proxy ratings of (1) the frequency, opportunity, and enjoyment of 15 non-ADL activities potentially within the capacity of a demented person, and (2) the frequency of a series of positive and negative affects, evident in clearly demarcated facial and bodily expressions. RESULTS:QOL ratings were reliably elicited. Family and institutional caregivers differed only in reports of opportunity for patient activity. Frequency of activities declined with increasing severity of dementia. The frequency of negative affects increased and positive affects declined with increasing severity of dementia, but correlations were weak. High QOL, defined by frequent activity and positive affect, was evident in a quarter of the sample. In multivariate models, functional and cognitive status independently predicted QOL among community-resident older adults; only absence of antipsychotics was related to QOL among older people in nursing homes. Patient education, a marker of premorbid state, independently predicted some activity patterns. CONCLUSIONS:Although the subjective world of the demented patient is not directly accessible, readily observable behaviors offer a basis for assessing QOL.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Albert SM,Del Castillo-Castaneda C,Sano M,Jacobs DM,Marder K,Bell K,Bylsma F,Lafleche G,Brandt J,Albert M,Stern Ydoi
10.1111/j.1532-5415.1996.tb01405.xsubject
Has Abstractpub_date
1996-11-01 00:00:00pages
1342-7issue
11eissn
0002-8614issn
1532-5415journal_volume
44pub_type
杂志文章,多中心研究abstract:OBJECTIVES:To compare the cognitive profile of a population representative sample with orthostatic hypotension (OH) with the profile of a sample without. DESIGN:Cross-sectional analysis of a prospective nationally representative population study. SETTING:The Irish Longitudinal Study on Ageing (TILDA). PARTICIPANTS:T...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12592
更新日期:2014-01-01 00:00:00
abstract::The course of untreated mild hypothyroidism was followed in 67 nursing home residents (mean age 78 years). The diagnosis was based on a normal free thyroxine index (FTI) and elevated thyrotropin concentration (TSH 4.6 to 15.0 microIU/mL, nl less than or equal to 4.5 microIU/mL. FTI and FSH were measured in follow-up 4...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1991.tb01648.x
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVES:To study the distribution of adiponectin isoforms in a group of very old patients. DESIGN:Cross-sectional. SETTING:Geriatric ambulatory clinic of the Department of Medicine at Policlinico "Tor Vergata." PARTICIPANTS:One hundred eight elderly adults (mean age 85.0+/-3.2) with or without a history of a prev...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02773.x
更新日期:2010-04-01 00:00:00
abstract::Physicians caring for individuals with life-altering, incurable illnesses often have a desire to convey a sense of hope while also helping their patients prepare for the end of life to minimize unnecessary suffering and grief. Unfortunately, in the United States, most people receive more-aggressive treatments toward t...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13392
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:To assess whether catheter replacement is associated with better clinical outcomes in individuals with long-term urinary catheters. DESIGN:Prospective, noninterventional study. PARTICIPANTS:Individuals (mean age 79.2±11.5) who had had an indwelling urinary catheter for longer than 7 days and a symptomatic ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15517
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:To determine the effectiveness of a behavior change intervention (BCI) with or without a pedometer in increasing physical activity in sedentary older women. DESIGN:Prospective randomized controlled trial. SETTING:Primary care, City of Dundee, Scotland. PARTICIPANTS:Two hundred four sedentary women aged 70...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2010.03127.x
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVES:To examine cross-national care and outcomes related to end-of-life experiences. DESIGN:Postdeath interviews and self-administered questionnaires completed with family caregivers of residents with dementia who died in long-term care settings or shortly after transfer. SETTING:One hundred eighty-three nursin...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03816.x
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVES:To investigate statin use and pain in people with cancer aged 70 to 79 and 80 and older. DESIGN:Cross-sectional. SETTING:Medical oncology outpatient clinic at the Royal Adelaide Hospital. PARTICIPANTS:Individuals aged 70 and older who presented consecutively between January 2009 and June 2010 (n = 385), o...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13051
更新日期:2014-10-01 00:00:00
abstract::To prevent falls effectively, one must first understand the underlying reasons. Although environmental factors are sometimes to blame, the fundamental cause is a decline in postural control which is partly age-related and partly due to pathologic changes in the central nervous system. Dizziness is a common complaint a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1980.tb01125.x
更新日期:1980-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the usefulness of standardized neuropsychological tests in the psychometric differentiation of patients with very mild or mild Alzheimer's Disease (AD) and/or major depression presenting in a tertiary clinic with memory/attention complaints. DESIGN:Controlled prospective clinicoexperimental desig...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章
doi:10.1111/j.1532-5415.1995.tb07402.x
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVES:To compare two sarcopenia definitions and examine the relationship between them and lower extremity function and other health related factors using data from the baseline examination of the Health Aging and Body Composition (Health ABC) Study. DESIGN:Observational cohort study. SETTING:Two U.S. communities...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2003.51534.x
更新日期:2003-11-01 00:00:00
abstract::Differing concepts of aging, i.e., a normative versus a pathologic process, are presented in historical perspective and are traced through selected writings from ancient China, India, Egypt, and Greece into more modern times. These is no consistent shift across epochs from one to the other perspective, and mixed persp...
journal_title:Journal of the American Geriatrics Society
pub_type: 历史文章,杂志文章
doi:10.1111/j.1532-5415.1982.tb07104.x
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVE:To determine if alcohol use is a risk factor for fall injury events among community-dwelling older persons. DESIGN:Case-control study. SETTING:South Miami Beach, Florida. PARTICIPANTS:320 persons 65 or older who sought treatment at six area hospitals for injuries resulting from falls; 609 controls, matched...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb01955.x
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVES:To identify factors that influence the breast cancer treatment decisions of women aged 80 and older. DESIGN:Medical record review. SETTING:One academic primary care clinic and two community health centers in Boston. PARTICIPANTS:Sixty-five women aged 80 and older diagnosed with breast cancer between 1994 ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03820.x
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To further validate an objective measure of physical illness burden, the Cumulative Illness Rating Scale (CIRS). DESIGN:Survey with correlation of CIRS ratings made from physician interviews and review of medical records with post-mortem ratings made independently at tissue autopsy. SUBJECTS:Victims of comp...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb05945.x
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:To determine if Staphylococcus aureus and Staphylococcus epidermidis, etiologic bacterial agents to late prosthetic joint infections (LPJI), are more prevalent in the oral flora of older individuals with rheumatoid arthritis (RA) than in an age and gender-matched nonarthritic control population (NA). DESIGN:...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1997.tb03092.x
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVES:To determine the association between usages of proton pump inhibitors (PPIs) and subsequent risk of pneumonia in dementia patients. DESIGN:Retrospective cohort study. SETTING:Taiwanese National Health Insurance Research Database. PARTICIPANTS:The study cohort consisted of 786 dementia patients with new PP...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14813
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVES:To assess changes in medication use after a diagnosis of dementia in individuals with type 2 diabetes mellitus. DESIGN:Difference-in-differences analysis of changes in the number of dispensed chronic medications between individuals with and without newly diagnosed dementia. SETTING:Integrated healthcare de...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14429
更新日期:2017-01-01 00:00:00
abstract::In 1976, 130 patients aged 70 or older were admitted to the Coronary Care Unit (CCU) at Toronto Western Hospital. Arrhythmias were noted in all but 24 percent. Digoxin was given to 53 patients, lidocaine to 24, propranolol to 28, and quinidine to 11. In 2 patients, cardioversion by direct current was required for supr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1979.tb06032.x
更新日期:1979-05-01 00:00:00
abstract:OBJECTIVES:To assess whether older age is independently associated with hemorrhage risk in patients with atrial fibrillation, whether or not they are taking warfarin therapy. DESIGN:Cohort study. SETTING:Integrated healthcare delivery system. Thirteen thousand five hundred fifty-nine adults with nonvalvular atrial fi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00828.x
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:Only limited data are available regarding smoking and health in later life and, in particular, in the older Chinese population. This paper reports the relationship between smoking and mortality in a Chinese cohort aged 70 years and older. SETTING:A population-based study conducted in Hong Kong. PARTICIPANT...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1999.tb01565.x
更新日期:1999-12-01 00:00:00
abstract::All living beings are at risk for experiencing infections; humans are no exception. The prestige and credibility of modern medicine is built in large part on achievements in preventing and treating infectious diseases. For most of human history, there was little that could be done to prevent and treat infections. Mill...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.16205
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:To prospectively validate and refine the 5-item "CRASH" screening tool for identifying older drivers needing a behind-the-wheel (BTW) test. DESIGN:Prospective observational study. SETTING:Geriatric and internal medicine primary care clinics affiliated with a tertiary care hospital and a local BTW program. ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15222
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:To determine how many individual patient data (IPD) reviews that included older people were available in MEDLINE and whether the effectiveness of treatments differed between older and younger individuals. DESIGN:Overview of IPD reviews. SETTING:A MEDLINE search was conducted for IPD reviews of randomized c...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.12830
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The American College of Cardiology (ACC) Geriatric Cardiology Section Leadership Council recently outlined 4 key domains (which are composed of 14 subdomains) that are important to assess in older adults with heart failure (HF). We sought to determine which geriatric domains/subdomains are routine...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16183
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To determine if home environmental hazards increase the risk of fall injury events among community-dwelling older persons. DESIGN:Population-based case-control study. SETTING:South Miami Beach, Florida. PARTICIPANTS:270 persons aged 65 years and older who sought treatment at six area hospitals for injuries...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1998.tb03799.x
更新日期:1998-06-01 00:00:00
abstract::Because of adverse publicity regarding increased risk of endometrial cancer in women receiving estrogen therapy, a 2-year prospective study was conducted in 1976 to determine the incidence of endometrial cancer in postmenopausal women. A retrospective study for the year 1975 was also added. A postmenopausal survey c...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1979.tb01673.x
更新日期:1979-09-01 00:00:00
abstract::The term "plastic surgeon" is oddly uninformative, although it seems likely that most people know what plastic surgeons do. How well can a sample of individuals encountered on the street describe what geriatricians do? To answer this question, we strolled through downtown Baltimore's Inner Harbor, armed with a video c...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12115
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Coffee and tea are two of the most widely consumed beverages worldwide and have been associated with reduced risk of mortality in some studies. However, it is unknown whether consumption of these beverages is associated with survival to an advanced age. OBJECTIVE:To examine associations of coffee and tea co...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16467
更新日期:2020-09-01 00:00:00
abstract::Senile dementia is one of the important medical-social-economic problems facing our society, estimated to affect some 60% of nursing home patients and of persons residing in the community. The course of dementia in these patients is affected not only by their age, medical complications, and the disease itself, but als...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1981.tb01261.x
更新日期:1981-12-01 00:00:00