Abstract:
:In this study an attempt was made to determine the relationship between cerebral amyloid angiopathy (AA) and other cerebrovascular lesions in the aged. The brains of 128 autopsy patients over 60 years of age were examined by both light and electron microscopy. The frequency of cerebral AA increased with age and was 58 percent in patients over the age of 90. The change was observed more often in women than in men. In 7 cases of severe AA, the temporal or occipital cortex was the most common site. Most cases of AA were complicated by the formation of senile plaques in the cortex. Electron microscopic examination revealed amyloid fibrils deposited in clusters in the media and adventitia of the vessels, destroying their structure. Some blood vessels on the surface of the cortex showed hyalinosis, angionecrosis, duplication of the wall, or fibrotic occlusion. AA is sometimes a cause of cerebral bleeding. Five cases of massive cerebral bleeding were found among patients aged 90 or older, including a temporal hematoma in a 92-year-old woman which was believed to be due to the marked AA noted in the temporal lobes. Small cortical infarctions were common in the temporal lobes.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Tomonaga Mdoi
10.1111/j.1532-5415.1981.tb01757.xsubject
Has Abstractpub_date
1981-04-01 00:00:00pages
151-7issue
4eissn
0002-8614issn
1532-5415journal_volume
29pub_type
杂志文章abstract:OBJECTIVES:To determine whether older adults with mild cognitive impairment (MCI), a condition not previously explored as a risk factor, have more hospitalizations and 30-day readmissions than those with normal cognition. DESIGN:Post hoc analysis of prospectively gathered data on incident hospitalization and readmissi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.13593
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To determine patient factors that predict use of physical or occupational therapy (PT/OT) services by elderly people. DESIGN:Time-series study of the relationship of PT/OT use to a variety of characteristics present at baseline. PARTICIPANTS:Eight-hundred nine community-dwelling men and women aged 65 and ol...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb02131.x
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVES:To compare the association between a restrictive transfusion strategy and cardiovascular complications during hospitalization for hip fracture with the association between a liberal transfusion strategy and cardiovascular complications, accounting for all transfusions from the emergency department to postacu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15371
更新日期:2018-07-01 00:00:00
abstract::Differing concepts of aging, i.e., a normative versus a pathologic process, are presented in historical perspective and are traced through selected writings from ancient China, India, Egypt, and Greece into more modern times. These is no consistent shift across epochs from one to the other perspective, and mixed persp...
journal_title:Journal of the American Geriatrics Society
pub_type: 历史文章,杂志文章
doi:10.1111/j.1532-5415.1982.tb07104.x
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVES:To determine whether there is racial variation in hospice enrollees in rates of hospitalization and hospice disenrollment and, if so, whether systematic differences in hospice provider patterns explain the variation. DESIGN:Longitudinal cohort study. SETTING:Hospice. PARTICIPANTS:Medicare beneficiaries (N...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15228
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:To examine the effect of social engagement (SE) on mortality in long-term care. DESIGN:A retrospective cohort study. SETTING:A 725-bed long-term care facility. PARTICIPANTS:A total of 927 long-term care residents who had SE measurements and did not have a serious communication problem. MEASUREMENTS:Minim...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb02624.x
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To identify age-related differences in the treatment of patients with acute myocardial infarction. DESIGN:Retrospective cohort study. SETTING:Two university-affiliated medical centers with integrated clinical programs. PATIENTS:329 patients admitted with acute myocardial infarction in 1988-1990 for whom co...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.1994.tb06553.x
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVES:To test whether Stepping On, a multifaceted community-based program using a small-group learning environment, is effective in reducing falls in at-risk people living at home. DESIGN:A randomized trial with subjects followed for 14 months. SETTING:The interventions were conducted in community venues, with a...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2004.52411.x
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVES:To assess the relationship between alcohol intake and mortality in a cohort of women aged 70 and older and to explore the relationship between level of alcohol use and changes in physical and mental health-related quality of life. DESIGN:National longitudinal surveys from 1996 to 2002. SETTING:Community ba...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00837.x
更新日期:2006-09-01 00:00:00
abstract::Although the field of frailty research has expanded rapidly, it is still a nascent concept within the clinical specialties. Frailty, conceptualized as greater vulnerability to stressors because of significant depletion of physiological reserves, predicts poorer outcomes in several medical specialties, including cardio...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14902
更新日期:2017-10-01 00:00:00
abstract::A study was made of 50 patients drawn at random from a Skilled Nursing Facility (SNF) attended by seven physicians. For 59 percent of these patients, polypharmacy was practiced but no substantiating diagnoses were recorded. Approximately half of the drugs were administered pro re nata. More drugs were prescribed in po...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1979.tb04139.x
更新日期:1979-03-01 00:00:00
abstract:OBJECTIVES:To determine whether increasing kyphosis angle was independently associated with poorer mobility as measured according to the Timed Up and Go Test (TUG), after controlling for other established risk factors. DESIGN:Prospective cohort study. SETTING:Eleven clinical centers in the United States. PARTICIPANT...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2010.03214.x
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:A widely held dictum in aging research is that heterogeneity in health increases with age, but the basis for this claim has not been fully investigated. We examined heterogeneity at different ages across health characteristics to describe variation and trends; we investigated the comparative importance of be...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16919
更新日期:2020-11-05 00:00:00
abstract:OBJECTIVE:To describe the prevalence and content of long-term care facility policies regarding the use of life-sustaining treatments (cardiopulmonary resuscitation (CPR), artificial hydration and nutrition, dialysis, antibiotics for life-threatening infections, transfer to acute care hospital) and advance directives in...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1994.tb06980.x
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVES:To compare the diagnosis and management of urinary tract infection (UTI) in hospitalized older people with clinical criteria and therapeutic guidelines. DESIGN:A retrospective case series of emergency hospital admissions collected over an 18-month period. SETTING:An acute general hospital in northwest Engl...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.02073.x
更新日期:2009-01-01 00:00:00
abstract::Tardive dyskinesia has emerged as a considerable public health hazard. In view of the overwhelming evidence that the elderly are particularly susceptible to this complication of neuroleptic use and the fact that there is no really effective treatment, neuroleptics should be avoided whenever possible in elderly patient...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1983.tb05417.x
更新日期:1983-02-01 00:00:00
abstract::This paper examines the relationship between physical fitness and activity among elderly males in the traditional rural community of Chetbesi, Nepal. It takes advantage of the unique character of the Hindu caste system to implement a quasiexperimental research design that approximates random assignment to high and low...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1985.tb07151.x
更新日期:1985-06-01 00:00:00
abstract:OBJECTIVES:To examine the association between hospitalization, critical illness, and infection occurring during middle- and late-life and structural brain abnormalities in older adults. DESIGN:Prospective cohort study. SETTING:Atherosclerosis Risk in Communities (ARIC) Study. PARTICIPANTS:A community sample of adult...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15470
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:To determine whether histamine2-receptor antagonist (H2RA) dose modified for renal impairment affects gastrointestinal (GI) disease control. DESIGN:Concurrent medical record review. SETTING:One hundred forty-six nursing facilities throughout the United States. PARTICIPANTS:Three hundred thirty-six patient...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1034/j.1600-0579.2003.00209.x
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:To assess the feasibility and validity of the International Dementia Alliance (IDEAL) instrument for Informal Caregivers (IDEAL-IC), which is based on the IDEAL instrument for professionals (IDEAL-P), for staging individuals with dementia. DESIGN:Cross-sectional. SETTING:Memory clinic of a university hospi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14205
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:For older adults screened by an Area Agency on Aging (AAA) in the National Aging Network, we aimed to examine the 12-month mortality rate for wait-listed callers compared with those who received services within 12 months, and to assess whether the mortality rate differed according to how quickly they receive...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16232
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:To use an expert consensus process to identify indicators of delirium features to help enhance bedside recognition of delirium. DESIGN:Modified Delphi consensus process to assign existing cognitive and delirium assessment items to delirium features in the Confusion Assessment Method (CAM) diagnostic algorit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.03996.x
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:To identify patient factors that influence physicians' decisions to recommend screening mammograms for older women. DESIGN:A cross-sectional survey including clinical case vignettes. PARTICIPANTS:Random sample of Massachusetts internists, obstetrician/gynecologists, family/general practice physicians, and ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb01371.x
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVES:Older black patients are at risk for underutilization of preventive services. Our objectives were to assess the delivery of five preventive services in Title 330-funded health centers in low income neighborhoods in Cleveland, Ohio, and to determine the association of health system factors and health status w...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb03902.x
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVES:Several studies have demonstrated that a large percentage of older people are inadequately immunized against tetanus. The aim of this study was to assess the immunity against tetanus in a group of individuals aged 69 and older and to examine the immune response to a single dose of tetanus toxoid. DESIGN:A c...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb06893.x
更新日期:2000-08-01 00:00:00
abstract::Primary carcinoma of the appendix, though rare, occurs often enough to warrant its inclusion in diagnostic possibilities when the symptoms of acute appendicitis, without leukocytosis, are present in geriatric patients. A case of mucinous adenocarcinoma of the appendix in an 88-year-old white woman is presented. The su...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb05665.x
更新日期:1982-09-01 00:00:00
abstract:OBJECTIVES:To clarify the effect of tooth loss on development of all-cause dementia and its subtypes in an elderly Japanese population. DESIGN:Prospective cohort study. SETTING:The Hisayama Study, Japan. PARTICIPANTS:Community-dwelling Japanese adults without dementia aged 60 and older (N = 1,566) were followed for ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14791
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To characterize rehabilitation services use of older adults according to fall-risk classification based on screening guidelines. DESIGN:Cross-sectional analysis of 2015 National Health and Aging Trends Study. SETTING:Study participants' homes. PARTICIPANTS:National sample of 7,440 community-dwelling Medic...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15625
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:Acute myocardial infarction (AMI) is an important cause of mortality and morbidity in older patients. The aim of this study was to determine the proportion of unselected admissions with AMI that is older than 75 years and to examine management and outcomes in this group. DESIGN:An historical cohort study of ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1999.tb02991.x
更新日期:1999-03-01 00:00:00
abstract:CONTEXT:Racial differences in receipt of cancer prevention services may be related to poorer outcomes for minorities. Understanding reasons for such differences could help target appropriate interventions. OBJECTIVES:To determine if racial differences exist in the use of cancer prevention services among older blacks a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb04746.x
更新日期:2000-07-01 00:00:00