Abstract:
OBJECTIVES:To determine whether the presence of high depressive symptoms (Center for Epidemiologic Studies Depression Scale (CES-D) score ≥ 14) diminished physical performance benefits after a comprehensive physical activity intervention in older adults. DESIGN:A post hoc analysis of data from the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) study, a single-blind randomized controlled trial comparing a moderate-intensity physical activity intervention (PA) with a successful aging control (SA). SETTING:Multicenter U.S. institutions participating in the LIFE-P trial. PARTICIPANTS:Four hundred twenty-four sedentary, noninstitutionalized adults aged 70 to 89. MEASUREMENTS:Depressive symptoms were assessed using the CES-D. Physical performance tests included the Short Physical Performance Battery (SPPB) and 400-m walk time (400 mw) at baseline and 6 and 12 months. RESULTS:Of the participants, 15.8% had high depressive symptom scores (CES-D ≥ 14). For participants with low depressive symptoms, SPPB scores improved more in the PA than the SA group over 12 months (adjusted score difference +0.70; P < .001 at 6 months and +0.58; P = .004 at 12 months), and 400 mw times improved in the PA group at 6 months (adjusted score difference -0.41 minutes; P = .02). For participants with high depressive symptoms, the difference in improvement fell short of statistical significance on the SPPB between the PA and SA groups (adjusted score difference +0.76 (P = .18) at 6 months and +0.94 (P = .12) at 12 months). CONCLUSION:The presence of high depressive symptoms did not substantially diminish physical performance benefits realized after a PA intervention in sedentary older adults.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Matthews MM,Hsu FC,Walkup MP,Barry LC,Patel KV,Blair SNdoi
10.1111/j.1532-5415.2011.03319.xsubject
Has Abstractpub_date
2011-03-01 00:00:00pages
495-500issue
3eissn
0002-8614issn
1532-5415journal_volume
59pub_type
杂志文章,多中心研究,随机对照试验abstract::After a 2-week washout period, 30 elderly hypertensive patients were treated with pindolol (a beta-adrenergic blocker) for 3 weeks. In 13 patients the reduction in blood pressure was satisfactory and treatment with pindolol was continued for another 4 weeks. In 17 patients the subsequent treatment was supplemented wit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1978.tb03680.x
更新日期:1978-08-01 00:00:00
abstract:OBJECTIVE:To determine the excess mortality associated with obesity (defined by body mass index (BMI)) in older people, with and without adjustment for other risk factors associated with mortality and for demographic factors. DESIGN:Retrospective cohort analysis of the Longitudinal Study of Aging (LSOA). SETTING:Nati...
journal_title:Journal of the American Geriatrics Society
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doi:10.1046/j.1532-5415.2001.49189.x
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abstract:OBJECTIVES:To determine the prevalence and predictors of adverse postoperative outcomes in older surgical patients undergoing noncardiac surgery. DESIGN:Prospective cohort study of consecutive patients undergoing noncardiac surgery in 1997. SETTING:A medical school-affiliated teaching community hospital. PARTICIPANT...
journal_title:Journal of the American Geriatrics Society
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doi:10.1046/j.1532-5415.2001.49212.x
更新日期:2001-08-01 00:00:00
abstract::It has long been thought that demographic aging and its attendant implications for health and social services is primarily a problem for industrialized wealthy countries. Nothing could be further from the truth since most older persons (and an increasingly higher number) reside in low-income countries. Through a descr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.16191
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:Factors specifically affecting compliance with continuous positive airway pressure (CPAP) in older patients with obstructive sleep apnea (OSA) have not been described. The purpose of this study is to determine which factors are associated with compliance and noncompliance in older patients, a growing segment...
journal_title:Journal of the American Geriatrics Society
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doi:10.1046/j.1532-5415.2001.49238.x
更新日期:2001-09-01 00:00:00
abstract::The second heart sound was studied by phonocardiography and carotid tracings in 103 elderly subjects without overt evidence of heart disease. Their ages ranged from 60 to 99 years. A normal type of splitting was found in 55.3%, and a single sound in 41.7%. The difference between these percentages and those found in 60...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1977.tb00665.x
更新日期:1977-08-01 00:00:00
abstract:OBJECTIVES:To determine the effect of patient characteristics and of specific guidelines that were developed for managing warfarin therapy in older adults and included in an in-house computer program on anticoagulation quality. DESIGN:Thirteen-month observational study. SETTING:Acute care, extended care, and rehabili...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2009.02675.x
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to test whether an intervention combining increased daytime physical activity with improvement in the nighttime environment improves sleep and decreases agitation in nursing home residents. DESIGN:A randomized trial. SETTING:One community nursing home in the Los Angeles, Calif...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1999.tb03833.x
更新日期:1999-07-01 00:00:00
abstract::The objectives of this study were to review the diagnostic, International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM), diagnosis related groups (DRGs), and common procedural terminology (CPT) coding and reimbursement issues (including Medicare Part B reimbursement for physicians) encounte...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1046/j.1532-5415.2002.50519.x
更新日期:2002-11-01 00:00:00
abstract::The initial assessments of cognitive, psychologic, and behavioral functioning of 17 adults enrolled in a day care program for victims of Alzheimer's disease are described. These evaluations by the staff, the patients themselves, and their primary caregivers made use of standardized quantitative measures, thus permitti...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1983.tb03398.x
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVES:To determine whether glycosylated hemoglobin (HbA1c) levels predict functional decline in older adults. DESIGN:Longitudinal cohort study. PARTICIPANTS:Community-dwelling, nursing home (NH)-eligible individuals with diabetes mellitus enrolled at On Lok between October 2002 and December 2008 (367 participant...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.04041.x
更新日期:2012-07-01 00:00:00
abstract::Close to 6 million Americans have Alzheimer's disease (AD) or Alzheimer's disease and related dementia (AD/ADRD). These high-need, high-cost patients are vulnerable to receiving poor quality uncoordinated care, ultimately leading to adverse health outcomes, poor quality of life, and misuse of resources. Improving the ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16621
更新日期:2020-07-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14105
更新日期:2016-05-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb03703.x
更新日期:1982-01-01 00:00:00
abstract::The relation of serum albumin concentration to age was assessed in a series of hospitalized medical patients. Those with disease states (e.g., dysproteinemia, renal insufficiency, hepatic dysfunction, malnutrition) potentially associated with abnormal serum albumin levels were excluded, leaving a study population of 1...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1979.tb01715.x
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVES:To determine whether a twice-weekly maintenance schedule of evening bright light exposure is effective in alleviating sleep maintenance insomnia on a long-term basis, after the establishment of a more favorable phase relationship between the core body temperature (CBT) rhythm and sleep. DESIGN:Subjects unde...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章
doi:10.1046/j.1532-5415.2002.50154.x
更新日期:2002-04-01 00:00:00
abstract::This study involved a 1st generation of 194 aged residents at the Philadelphia Geriatric Center plus 2nd and 3rd generations of 357 and 306 offspring, respectively. Serum cholesterol levels (including type of abnormality) and triglyceride levels were determined. The results suggest that hyperlipidemia at all ages is r...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1975.tb00896.x
更新日期:1975-11-01 00:00:00
abstract:OBJECTIVES:To describe the association between frailty and health status, the progression of frailty, and the relationship between frailty and mortality in older men. DESIGN:Cross-sectional and prospective cohort study. SETTING:Six U.S. clinical centers. PARTICIPANTS:Five thousand nine hundred ninety-three community...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2007.01259.x
更新日期:2007-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2001.4911244.x
更新日期:2001-11-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1985.tb01777.x
更新日期:1985-10-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1532-5415.2000.tb03145.x
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the use of pentoxifylline to treat impotence in men with mild to moderate penile vascular insufficiency. DESIGN:Double-blind randomized clinical trial. SETTING:Sexual Dysfunction Clinic at VA Medical Center, Sepulveda, CA. PARTICIPANTS:Convenience sample of couples. INTERVENTION:Twelve weeks o...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1993.tb06941.x
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVES:To assess the physical and mental health status of older long-term cancer survivors. DESIGN:Cohort study using propensity score methods to control for baseline differences between cancer survivors and controls. SETTING:General community population in the United States. PARTICIPANTS:Nine hundred sixty-four...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.00507.x
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVES:To determine whether body mass index (BMI) is independently associated with cognitive function in postmenopausal women and the relationship between body fat distribution as estimated by waist-hip ratio (WHR). DESIGN:Cross-sectional data analysis. SETTING:Baseline data from the Women's Health Initiative (WH...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02969.x
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVES:To assess the effect of chronic renal failure (CRF) on quality of life (QOL). DESIGN:Controlled cross-sectional study. SETTING:All 13 dialysis units in the French Lorraine region and six departments of a Nancy hospital. PARTICIPANTS:One hundred sixty-nine older patients with end-stage renal disease (ESRD)...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2003.51062.x
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVES:To examine whether sleep disturbance is associated with poor physical function in older veterans in an adult day healthcare (ADHC) program. DESIGN:Cross-sectional. SETTING:One ADHC program in a Veterans Affairs Ambulatory Care Center. PARTICIPANTS:Older veterans (N = 50) enrolled in a randomized controlle...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
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更新日期:2015-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13591
更新日期:2015-09-01 00:00:00
abstract::Quality-of-life considerations in physicians' decisions on life-sustaining therapy were explored using a patient management problem (PMP) depicting acute respiratory failure in an elderly man with chronic pulmonary disease; 205 internal medicine and family medicine physicians were interviewed. The physicians' percepti...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1985.tb07135.x
更新日期:1985-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the skeletal health, calcium, and vitamin D homeostasis of patients upon their entry to a long-term-care facility. Factors that could contribute to the risk of future osteoporotic fractures were also evaluated. DESIGN:Cross-sectional study. PATIENTS:Two hundred eighty-seven consecutive admission...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb06452.x
更新日期:1993-10-01 00:00:00
abstract::The purpose of this study was to compare attitudes toward the use of long-term care between older Japanese Americans (n = 1,244) and older Caucasian Americans (n = 1,354). When presented with a hypothetical situation in which they have dementia, 39% of older Japanese Americans and 42% of older Caucasians intended to b...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2002.50275.x
更新日期:2002-06-01 00:00:00