Interferon production by leukocytes in children with otitis media with effusion.

Abstract:

:We have previously shown that leukocyte cultures of children suffering from recurrent respiratory tract infections produce less interferon (IFN) than those of healthy children. In the present study this tentative marker of recurrent infections was used to study the pathogenetic background of otitis media with effusion (OME). Altogether 57 consecutive children, aged 2-11 years, who came for tympanostomy and/or adenoidectomy were divided into three subgroups: 25 of them had OME and a history of recurrent acute otitis media (rAOM/OME+), 20 had OME without an infectious background (inf-/OME+), and 12 had a history of recurrent upper respiratory infections (inf +/OME-) without OME. All the children were free of acute illness at the time of sampling. Differences between the groups were seen in IFN yields when leukocyte cultures were stimulated with adeno-, rhino-, corona-, respiratory syncytial or influenza A viruses. Leukocytes from inf-/OME+ children produced more IFN than those of the other two groups. Though no sex differences in the IFN responses were seen among rAOM/OME+ and inf +/OME- children, leukocytes from inf-/OME+ girls produced significantly higher amounts of IFN than those of inf-/OME+ boys, or rAOM/OME+ and inf +/OME- children. These differences between clinically different groups of children support the view that the etiology of OME can be heterogeneous.

authors

Pitkäranta A,Hovi T,Karma P

doi

10.1016/0165-5876(95)01231-1

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

25-33

issue

1-2

eissn

0165-5876

issn

1872-8464

pii

0165-5876(95)01231-1

journal_volume

34

pub_type

杂志文章
  • Adaptation and validation of receptive expressive emergent Language Test-3: Evidence from Hindi speaking children with cochlear implant.

    abstract:INTRODUCTION:Selection of an effective tool for assessment of language learning outcomes in post cochlear implantation is always an important but challenging task. Receptive expressive emergent language test-3rd Eds. (REELT-3) is one of the comprehensive language assessment tools used in India. In case of administratio...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2020.109891

    authors: Kumar V,Mehta R

    更新日期:2020-05-01 00:00:00

  • The "Frankentower:" A clinician-driven approach to enhancing endoscopic data technology.

    abstract:OBJECTIVE:To develop a more efficient endoscopy tower and evaluate its capability to improve retrieval and storage of videos across 6 clinical sites. METHODS:Descriptive study that took place at tertiary care Pediatric Otolaryngology Department over a 2 year period. In collaboration with our Information Services Depar...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2020.110486

    authors: Ngombu S,Payne LM,Cecil JM,Grischkan JM

    更新日期:2021-01-01 00:00:00

  • Pediatric laryngeal tumors and demographics, management, and survival in laryngeal squamous cell carcinoma.

    abstract:OBJECTIVES:To evaluate the prevalence and features of pediatric laryngeal malignancies and to review the demographics, management, and survival of pediatric patients with laryngeal squamous cell carcinoma as compared to adult patients. METHODS:Patients aged 0 (younger than 1) to 18 with laryngeal malignancy identified...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2020.110507

    authors: Forsyth AM,Camilon PR,Tracy L,Levi JR

    更新日期:2021-01-01 00:00:00

  • Acute mastoiditis: 20 years of experience with a uniform management protocol.

    abstract:OBJECTIVES:To characterize the clinical presentation of pediatric patients who, upon AM diagnosis, also had imaging-diagnosed ICCs (ID-ICCs); to define the group of AM patients at risk of developing ID-ICCs; and to update knowledge about organisms causing AM. STUDY DESIGN:Analysis of all AM patients admitted between 1...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2019.07.014

    authors: Mansour T,Yehudai N,Tobia A,Shihada R,Brodsky A,Khnifies R,Barzilai R,Srugo I,Luntz M

    更新日期:2019-10-01 00:00:00

  • Osteoblastoma of the temporal bone presenting as facial paralysis.

    abstract::Osteoblastomas of the head region are rare lesions. This paper describes a case of a 4-year-old child with an osteoblastoma of the temporal bone presenting as a facial paralysis. Only 6 previous cases have been reported and none with nerve involvement. A review of the tumor, its differential diagnosis, clinical course...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/s0165-5876(85)80086-0

    authors: Naclerio RM,Jenkins HA,Herzog JA

    更新日期:1985-03-01 00:00:00

  • Early myelination patterns in the central auditory pathway of the higher brain: MRI evaluation study.

    abstract:OBJECTIVE:The purpose of this study was to use magnetic resonance imaging (MRI) to investigate the early myelination patterns of the central auditory pathway and then compare the data with past histological research. We observe the MRI signal intensity of the central auditory pathway and clarify the time course differe...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2008.06.011

    authors: Sano M,Kuan CC,Kaga K,Itoh K,Ino K,Mima K

    更新日期:2008-10-01 00:00:00

  • Expression of CD34-antigen in nasopharyngeal angiofibromas.

    abstract::Formalin-fixed, paraffin-embedded and frozen tissues of 24 patients with primary nasopharyngeal angiofibroma, of whom seven had recurrences, were studied immunohistochemically for the expression of CD34 antigen using two different antibodies (HPCA-1 and QBEND 10). In all cases, there was an exclusive staining of endot...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/s0165-5876(98)00072-x

    authors: Beham A,Regauer S,Beham-Schmid C,Kainz J,Stammberger H

    更新日期:1998-08-01 00:00:00

  • Current trends in pediatric tracheotomy.

    abstract::A retrospective analysis was performed on 103 pediatric patients, less than 5 years of age, undergoing tracheotomy at New York Hospital between 1980 and 1990. Charts were reviewed with respect to primary diagnosis, indication for tracheotomy, duration of the tracheotomy, complication rate and mortality rate. Approxima...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/0165-5876(95)01175-b

    authors: Ward RF,Jones J,Carew JF

    更新日期:1995-07-01 00:00:00

  • Paraoxonase and arylesterase activity and total oxidative/anti-oxidative status in patients with chronic adenotonsillitis.

    abstract:OBJECTIVES:The aim of this study was to investigate serum paraoxonase, arylesterase activities along with determination of oxidative status via measurement of total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) in children with recurrent adenotonsillitis during pre- and post-aden...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2011.07.017

    authors: Koc S,Aksoy N,Bilinc H,Duygu F,Uysal IÖ,Ekinci A

    更新日期:2011-11-01 00:00:00

  • Obstructive sleep apnea in obese children and adolescents, treatment methods and outcome of treatment - A systematic review.

    abstract:OBJECTIVES:To systematically review and discuss the outcome of treating obstructive sleep apnea (OSA) in obese children and adolescents. METHODS:In February 2016 Pub Med was searched using a predetermined string to retrieve all relevant articles. The search identified 518 publications. In total 16 articles were includ...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijporl.2016.06.017

    authors: Andersen IG,Holm JC,Homøe P

    更新日期:2016-08-01 00:00:00

  • Clinical characterization of novel chromosome 22q13 microdeletions.

    abstract:INTRODUCTION:The advent of chromosome microarray analysis (CMA) for evaluation of patients with multiple congenital anomalies has made it possible to define chromosomal imbalances with greater precision and resolutions significantly smaller than possible by standard G-banded chromosome analysis. We describe two patient...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2016.12.008

    authors: Ha JF,Ahmad A,Lesperance MM

    更新日期:2017-04-01 00:00:00

  • Congenital absence of the epiglottis.

    abstract::The congenital absence of the epiglottis is a very rare anomaly. We present a patient who has a complete absence of the epiglottis, illustrated with an endoscopic photograph, review the literature and discuss the management of patients with this condition. ...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/s0165-5876(98)00082-2

    authors: Koempel JA,Holinger LD

    更新日期:1998-10-15 00:00:00

  • Acoustic rhinometry, spirometry and nitric oxide in relation to airway allergy and smoking habits in an adolescent cohort.

    abstract:OBJECTIVE:This study aimed to analyze upper and lower airway function and the impact of smoking habits in a cohort of allergic and healthy adolescents. The influence of smoking habits on the outcomes of rhinitis and asthma is well documented, but only few reports are available showing smoke related upper airway impairm...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2010.10.029

    authors: Irander K,Borres MP,Palm JP

    更新日期:2011-02-01 00:00:00

  • Beta-lactamase production and bacterial tolerance in recurrent acute otitis media.

    abstract::Different reasons for treatment failure or relapse of acute otitis media (AOM) have been suggested. In this study 38 children (8 treatment failures, 13 relapses of AOM within one month and 17 with a new AOM) were compared to 25 matching healthy children, regarding beta-lactamase producing bacteria and tolerance to pen...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/0165-5876(91)90147-4

    authors: Roos K,Lind L,Holm SE

    更新日期:1991-04-01 00:00:00

  • Securing stent during multi-stage laryngotracheoplasty--an evolved technique.

    abstract:BACKGROUND:Multi-stage laryngotracheoplasty (LTP) typically requires a stent be secured to the airway for 2-6 weeks. Our technique has evolved over time to securing the stent to the strap muscles and tying a series of knots long enough to leave the suture tail protruding through the skin incision, which simplifies sten...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2015.06.015

    authors: Siegel B,Bent JP

    更新日期:2015-09-01 00:00:00

  • Bone-anchored hearing aid: why do some patients refuse it?

    abstract:OBJECTIVE:Bone-anchored hearing aid (BAHA™) is a proven tool to improve hearing. Nevertheless, there are patients who are candidates for BAHA™ implants that end up refusing the surgery. The objective of this study is to review our BAHA™ experience with particular emphasis on reasons behind the refusal of some candidate...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2013.11.010

    authors: Zawawi F,Kabbach G,Lallemand M,Daniel SJ

    更新日期:2014-02-01 00:00:00

  • Functional outcome of sequential bilateral cochlear implantation in young children: 36 months postoperative results.

    abstract:OBJECTIVE:To examine the effects of sequential bilateral cochlear implantation (CI) on the life of young children after 36 months of bilateral implant use. METHOD:Thirty-five children were assessed prior to and 3 until 36 months after activation of the second CI. Main outcome measures were: the Categories of Auditory ...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2009.01.009

    authors: Scherf FW,van Deun L,van Wieringen A,Wouters J,Desloovere C,Dhooge I,Offeciers E,Deggouj N,De Raeve L,De Bodt M,Van de Heyning PH

    更新日期:2009-05-01 00:00:00

  • Abduction of the condyle head leads to condylar resorption: A radiologic study in children with intracapsular fractures.

    abstract:OBJECTIVE:This study aimed to explore and make an understanding of absorption existed in children with intracapsular fractures. METHODS:The sample was composed of all children (less than 12 years) who presented with intracapsular fractures within a 5-year period (January 2011 to April 2016). Data about age, gender, da...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2019.05.013

    authors: Zhou HH,Lv K,Yang RT,Li Z,Yang XW,Li ZB

    更新日期:2019-08-01 00:00:00

  • Effect of early activation of cochlear implant on electrode impedance in pediatric population.

    abstract:OBJECTIVES:To assess the evolution of electrode impedance after the early fitting of audio processors (activation after one-day) and classical fitting (activation after one-month) over an up-to-one year after cochlear implant (CI) surgery. METHODS:A retrospective cohort study on Fifty-two CI recipients divided into tw...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2020.110543

    authors: Alhabib SF,Abdelsamad Y,Yousef M,Alzhrani F,Hagr A

    更新日期:2021-01-01 00:00:00

  • Risk factors for laryngeal trauma and granuloma formation in pediatric intubations.

    abstract:OBJECTIVE:Intubation has been associated with laryngeal injury that often resolves spontaneously without complication. We present a case of a child intubated for less than 48 hours, who presented with dysphonia and intermittent dyspnea two months after intubation due to epiglottic and vocal process granulomas. This is ...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijporl.2018.01.008

    authors: Jang M,Basa K,Levi J

    更新日期:2018-04-01 00:00:00

  • Outcomes of BAHA connect vs BAHA attract in pediatric patients.

    abstract:INTRODUCTION:Two of the most commonly employed bone-anchored hearing implant (BAHI) systems are the BAHA Connect and BAHA Attract. The BAHA Connect uses a skin-penetrating titanium abutment. The BAHA Attract uses an implanted magnet, leaving the overlying skin intact. Limited data is available on the difference in comp...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2020.110125

    authors: Oberlies NR,Castaño JE,Freiser ME,McCoy JL,Shaffer AD,Jabbour N

    更新日期:2020-08-01 00:00:00

  • Prevalence and risk factors for auditory neuropathy spectrum disorder in a screened newborn population at risk for hearing loss.

    abstract:OBJECTIVE:To determine the prevalence of Auditory Neuropathy Spectrum Disorder (ANSD) among infants with sensorineural hearing loss (SNHL) and discuss the risk factors. METHODS:The study group was comprised of children diagnosed with ANSD. Criteria for inclusion in the study group were as follows: permanent sensorineu...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2012.08.001

    authors: Bielecki I,Horbulewicz A,Wolan T

    更新日期:2012-11-01 00:00:00

  • Declining prevalence of pediatric sudden deafness during the past two decades.

    abstract:OBJECTIVE:This study compared the prevalence of sudden deafness (SD) in children to investigate the evolution of pediatric SD during the past two decades. METHODS:From 1996 to 2005, totaling 358 SD patients were experienced. Of them, 25 patients (7%) aged <15 years were assigned to Group A. In contrast, 5 patients (2%...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2019.01.029

    authors: Zhang BY,Young YH

    更新日期:2019-04-01 00:00:00

  • Patterns of Internet and smartphone use by parents of children attending a pediatric otolaryngology service.

    abstract:OBJECTIVES:To assess Internet use and the influence of smartphones on health-information seeking by parents and carers of children with ENT conditions. METHODS:A paper-based questionnaire was circulated to parents attending otolaryngology services in both the out-patient and day-case settings at a tertiary referral ce...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2013.01.021

    authors: Glynn RW,O'Duffy F,O'Dwyer TP,Colreavy MP,Rowley HM

    更新日期:2013-05-01 00:00:00

  • Central nervous system complications secondary to oto-rhinologic infections. An analysis of 39 pediatric cases.

    abstract::Fifty-eight central nervous system complications were noted in 39 pediatric patients with a primary oto-rhinological infection. The ages ranged from 1 to 15 years. Eleven patients (25%) had more than one complication. 12.8% of the cases died. Leptomeningitis was the most common intracranial complication (54%) Lateral ...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/0165-5876(92)90019-l

    authors: Kraus M,Tovi F

    更新日期:1992-11-01 00:00:00

  • Endoscopically placed nitinol stents for pediatric tracheal obstruction.

    abstract:OBJECTIVE:To provide preliminary clinical data regarding endoscopically placed nitinol stents for children with tracheal obstruction as a temporizing measure to allow for trach tube decannulation while awaiting growth to allow for tracheal resection. METHODS:This case series describes the experiences of two children (...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/s0165-5876(02)00241-0

    authors: Prasad M,Bent JP,Ward RF,April MM

    更新日期:2002-11-11 00:00:00

  • Cartilage within a thyroglossal duct anomaly.

    abstract::A case of thyroglossal duct anomaly showing an unusual finding of foci of cartilage is presented. Although the concept of choristoma may explain the pathogenesis of cartilage within the present congenital anomaly, the histologic features were more in favor of a metaplastic process. In addition, the history of recurren...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/0165-5876(88)90072-9

    authors: Tovi F,Barki Y,Maor E

    更新日期:1988-05-01 00:00:00

  • The role of C.T. scans in managing the orbital complications of ethmoiditis.

    abstract::Thirty-three cases of ethmoidities with orbital complications were reviewed to determine the accuracy of clinical diagnosis and the benefit of CT scans in planning treatment. Patients were classified according to the Schramm et al. 1982 criteria of orbital involvement with ethmoiditis: periorbital cellulitis with chem...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/0165-5876(88)90062-6

    authors: Gutowski WM,Mulbury PE,Hengerer AS,Kido DK

    更新日期:1988-05-01 00:00:00

  • A quality study of family-centered care coordination to improve care for children undergoing tracheostomy and the quality of life for their caregivers.

    abstract:IMPORTANCE:Approximately 4000 U.S. children undergo tracheostomy yearly [1], and these surgeries often result in hospital re-admissions that have definite cost and caregiver burdens due to complications that are avoidable with proper training and support. OBJECTIVE:To assess the impact of a Family-Centered Care Coordi...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/j.ijporl.2017.05.025

    authors: Hartnick C,Diercks G,De Guzman V,Hartnick E,Van Cleave J,Callans K

    更新日期:2017-08-01 00:00:00

  • Can nasal endoscopy be used to predict residual symptoms after adenoidectomy for nasal obstruction?

    abstract:BACKGROUND:the efficacy of adenoidectomy in relieving nasal symptoms has been questioned. Although enlarged adenoids are often blamed for nasal obstruction, other causes can be missed if examination is not thorough. We suggest that endoscopy at the time of adenoidectomy may be useful to confirm large adenoids and exclu...

    journal_title:International journal of pediatric otorhinolaryngology

    pub_type: 杂志文章

    doi:10.1016/s0165-5876(01)00452-9

    authors: Kubba H,Bingham BJ

    更新日期:2001-05-11 00:00:00