Abstract：
OBJECTIVES:To characterize the clinical presentation of pediatric patients who, upon AM diagnosis, also had imaging-diagnosed ICCs (ID-ICCs); to define the group of AM patients at risk of developing ID-ICCs; and to update knowledge about organisms causing AM. STUDY DESIGN:Analysis of all AM patients admitted between 1997 and 2018 and treated according to an obligatory protocol including both brain imaging and sampling for bacterial culture upon clinical diagnosis of AM. RESULTS:Of 166 admitted patients (0.5-19 years old) 22 (13%) already had ID-ICCs. In patients who, on admission, had already received antibiotics for acute otitis media (AOM) and also had CRP (C-reactive protein) levels above 93.5 mg/L, the risk of ID-CC was increased by 22.5-fold (P < 0.0001). Bacterial culture results were available for all patients and were positive in 115 (69%). Organisms most commonly found in patients without prior antibiotic treatment were group A Streptococcus pyogenes (53%), Streptococcus pneumoniae (23%), and Haemophylus influenzae (11%), while with prior antibiotic treatment they were Fusobacterium necrophorum (21%), Streptococcus pyogenes (18%) and Pseudomonas aeruginosa (18%). CONCLUSIONS:Since the risk of ID-ICC in patients with the abovementioned CRP and prior antibiotic treatment was significantly higher than in the others, these high-risk patients should undergo diagnostic imaging on admission. Antibiotic treatment prior to AM development may promote growth of non-AOM pathogen.
journal_name
Int J Pediatr Otorhinolaryngoljournal_title
International journal of pediatric otorhinolaryngologyauthors
Mansour T,Yehudai N,Tobia A,Shihada R,Brodsky A,Khnifies R,Barzilai R,Srugo I,Luntz Mdoi
10.1016/j.ijporl.2019.07.014subject
Has Abstractpub_date
2019-10-01 00:00:00pages
187-191eissn
0165-5876issn
1872-8464pii
S0165-5876(19)30323-4journal_volume
125pub_type
杂志文章abstract：OBJECTIVES:The purpose of the study was to evaluate the treatment effects of functional appliances (FAs) on upper airway dimensions in growing Class II patients with mandibular retrognathism. METHODS:Five databases and the references of identified articles were electronically searched for relevant studies that met our...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章,meta分析,评审
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journal_title：International journal of pediatric otorhinolaryngology
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journal_title：International journal of pediatric otorhinolaryngology
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
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journal_title：International journal of pediatric otorhinolaryngology
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journal_title：International journal of pediatric otorhinolaryngology
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doi：10.1016/j.ijporl.2005.05.021
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journal_title：International journal of pediatric otorhinolaryngology
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journal_title：International journal of pediatric otorhinolaryngology
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doi：10.1016/j.ijporl.2018.07.039
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journal_title：International journal of pediatric otorhinolaryngology
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更新日期：2010-07-01 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2014.03.038
更新日期：2014-07-01 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2005.09.013
更新日期：2006-05-01 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2011.03.006
更新日期：2011-06-01 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2007.07.018
更新日期：2007-11-01 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2009.06.007
更新日期：2009-10-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.ijporl.2006.05.004
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
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pub_type： 杂志文章,多中心研究
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doi：10.1016/j.ijporl.2004.02.014
更新日期：2004-07-01 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2007.05.020
更新日期：2007-09-01 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
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更新日期：2000-07-14 00:00:00
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journal_title：International journal of pediatric otorhinolaryngology
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journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
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更新日期：2018-02-01 00:00:00
