Abstract:
:Neuroimaging in anorexia nervosa has revealed morphological and functional alterations, most of which are currently interpreted as consequences of the anorectic state that are reversible, at least partially, after weight gain. Enlargement of CSF spaces, mainly of cortical sulci, is evident on CT and MRI. This reversible shrinkage of brain tissue ("pseudoatrophy") also affects the pituitary gland. A functional imaging study with positron emission tomography (PET) revealed caudate hyperactivity during the anorectic state, and several mild right-left asymmetries possibly related to alterations of mental state (vigilance, depression, etc.) have also been reported in bulimia nervosa. New aspects may be added, when techniques to image functional brain activation during specific tasks and regional receptor binding capacities are used to study anorexia nervosa.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Herholz Kdoi
10.1016/0165-1781(96)02990-3subject
Has Abstractpub_date
1996-04-16 00:00:00pages
105-10issue
1eissn
0165-1781issn
1872-7123pii
0165178196029903journal_volume
62pub_type
杂志文章,评审abstract::Both major depressive disorders (MDD) and schizophrenia (SZ) have been associated with reductions in slow-wave (Stages 3 and 4) sleep, although these findings are controversial. The present study compared quantitative EEG measures of slow-wave activity (0.5-4 Hz) during non-REM (NREM) sleep among age-matched, symptoma...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(00)00181-5
更新日期:2000-09-11 00:00:00
abstract::Although married women are increasingly participating in paid labor, housework remains their primary responsibility. This uneven distribution of housework could have a negative impact on their mental health. In this study, we examined the association between satisfaction with husbands' participation in housework and s...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.01.039
更新日期:2018-03-01 00:00:00
abstract::Impairments on neuropsychological and eye movement tasks have been demonstrated in schizophrenic patients and also reported in their unaffected relatives. However, it is not clear to what extent these phenotypes overlap. This study examined the relationship between specific eye movement and neuropsychological measures...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.05.008
更新日期:2009-08-15 00:00:00
abstract::Low plasma total testosterone (T) levels may influence the sense of well-being and produce depressive symptomatology, increasing the risk of suicide. In a previous study, we reported reduced serum T levels in male psychiatric patients after a suicide attempt. The reduction was more pronounced in subjects who used viol...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.08.001
更新日期:2009-11-30 00:00:00
abstract::Childhood trauma exposure has been associated with a clinically relevant mixed phenotype of psychopathology composed of depressive, anxiety, and psychosis symptoms, across healthy and clinical samples. Altered stress-reactivity after exposure to childhood trauma may be a plausible underlying mechanism explaining this ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.12.012
更新日期:2018-02-01 00:00:00
abstract::Pharmacological treatments for alcohol use disorder show a modest effect, and they are unavailable in certain countries. The study's aim is to investigate the effects of gabapentin on alcohol drinking. One hundred twelve Thai individuals with alcohol dependence and very high alcohol consumption were randomly assigned ...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2018.09.002
更新日期:2018-12-01 00:00:00
abstract::This report explores the relationship between age of first onset of major depression and other demographic and clinical features in the first 1500 patients entering the Sequenced Treatment Alternative to Relieving Depression (STAR*D) study. Outpatients, 18-75 years of age, with nonpsychotic major depressive disorder (...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.07.004
更新日期:2004-12-15 00:00:00
abstract::In this study, 53 Chinese COPD moderate outpatients and 50 health controls, matched for age, family income and education level, were recruited to assess the prevalence of Alexithymia and its relationship to socio-demographic factors and pulmonary function. Alexithymia was measured with 20-item Toronto Alexithymia Scal...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.10.018
更新日期:2012-07-30 00:00:00
abstract::Childhood adversity is associated with a range of mental disorders, functional impairment and higher health care costs in adulthood. In this study we evaluated if childhood adversity was predictive of adverse clinical and functional outcomes and health care costs in a sample of patients at ultra-high risk (UHR) for de...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.psychres.2016.11.014
更新日期:2017-01-01 00:00:00
abstract::Differences in antipsychotic treatment response, clinical course and outcome of schizophrenia could be related to gender-related cerebral differences in anatomy and function. The aim of the study was to assess sex differences in the striatal dopamine D2 receptor binding in 15 drug-naive schizophrenic patients (seven m...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2003.05.001
更新日期:2004-01-15 00:00:00
abstract::Clinical research across the developmental spectrum increasingly reveals the nuanced ways in which emotion and cognition can work to either support or derail rational (i.e., healthy or goal-consistent) decision making. However, psychological theories offer discrepant views on how these processes interact, and on wheth...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2019.01.048
更新日期:2019-03-01 00:00:00
abstract::In schizophrenia, psychomotor slowing and stereotypy are poorly delineated from cognitive deficits like diminished processing speed. Inpatients' performance outcomes on a line-copying task, a task assessing stereotypy and a processing-speed task are compared. Results suggested that psychomotor slowing and stereotypy a...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.01.017
更新日期:2008-10-30 00:00:00
abstract::The Cocaine Craving Questionnaire was administered to 205 cocaine addicts. A 6/5 cut-off corresponded to the scale's best performance. Reliability was 0.803. Receiver Operating Characteristic analysis resulted in an area under the curve of 0.7199 +/- 0.0384, and dimensionality resulted in a three-factor solution. The ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.01.010
更新日期:2006-06-15 00:00:00
abstract::Animal models and clinical trials in humans suggest that probiotics can have an anxiolytic effect. However, no studies have examined the relationship between probiotics and social anxiety. Here we employ a cross-sectional approach to determine whether consumption of fermented foods likely to contain probiotics interac...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.04.023
更新日期:2015-08-15 00:00:00
abstract::No prospective studies of first psychotic episodes have explored sex differences in smoking cessation. The aim of this study was to determine the influence of sex and substance abuse on smoking cessation during an 8-year follow-up of patients after a first psychotic episode. Logistic regression modeling was used to id...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.08.005
更新日期:2012-01-30 00:00:00
abstract::Evaluation of the outcomes of our decisions may instigate comparisons of our actual outcome with those of others (social comparisons) or comparisons with alternative outcomes of choices not made (private comparisons). Previous research has suggested a deficit in attention to social information among individuals with a...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.01.036
更新日期:2014-05-30 00:00:00
abstract::Using functional magnetic resonance imaging, we measured amygdala reactivity to faces varying on threat intensity in patients with generalized social phobia (GSP) and healthy controls. GSP patients exhibited greater amygdala reactivity to threat faces at high and moderate intensities. More subtle displays of social th...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.05.001
更新日期:2010-08-30 00:00:00
abstract::There are some reports that catecholamines may modulate the production of monocytic cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF alpha). The present study was carried out in order to examine the effects of noradrenaline (10(-5), 10(-6) and 10(-7) M), clonidine (10(-5), 10(-6) and 10(-7) ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(00)00216-x
更新日期:2000-11-20 00:00:00
abstract::Behavioural interventions show promising results among patients with mild- to moderate depression. However, whether tobacco use moderates the effects of these interventions is not known. In the present study, we examined whether patients suffering from mild-to-moderate depression differed in their response to prescrib...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.psychres.2018.01.006
更新日期:2018-03-01 00:00:00
abstract::Since the magnitude of the first-night effect has been shown to be a function of medical conditions and of settings in which polysomnographies are performed, it is essential to evaluate the habituation phenomenon in each case in order to determine the optimal recording methodology. A first-night effect was evidenced i...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00185-9
更新日期:2003-09-30 00:00:00
abstract::The association between cognitive performance and general functioning in depression is controversial. The present study evaluated the association between cognitive dysfunction and major depressive disorder (MDD, N=70) as compared with age- and gender-matched healthy controls (n=206) and its relationship to general fun...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.12.001
更新日期:2010-04-30 00:00:00
abstract::Spouse abuse is listed as a V code in DSM-IV-TR and worthy of further clinical investigation, although research has focused predominantly on the victims of family violence rather than the batterers themselves. This study tests the hypotheses that (a) batterers have a neurocognitive bias favoring negative affect (aggre...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.12.013
更新日期:2010-04-30 00:00:00
abstract::Since abnormalities in distal upper limb development are among the minor physical anomalies associated with schizophrenia we attempted to determine whether patients with schizophrenia can be identified on the basis of specific morphologic and dermatoglyphic features of the hand. Photographs and prints of the hands of ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.08.026
更新日期:2013-12-30 00:00:00
abstract::P300 event-related brain potential (ERP) amplitude is smaller in patients with schizophrenia compared to unaffected controls, but whether left temporal component amplitude is also smaller is debated. The present study employed meta-analytical methods to quantitatively assess previous P300 schizophrenia asymmetry findi...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/s0165-1781(01)00297-9
更新日期:2001-10-10 00:00:00
abstract::Sherrington et al. (1988) reported linkage between markers located on the 5q11-q13 region of chromosome 5 and schizophrenia in five Icelandic and two British families. To date, however, all attempts to replicate the initial finding have failed. Using three markers of chromosome 5, we have studied 28 additional French ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(92)90021-t
更新日期:1992-12-01 00:00:00
abstract::Thirty-five schizophrenic patients in the early stages of illness, 26 of their healthy siblings, and 35 normal control subjects performed the Continuous Performance Test, Identical Pairs version (CPT-IP). Both schizophrenic patients and their siblings were significantly impaired in their attentional performance compar...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(94)90020-5
更新日期:1994-12-01 00:00:00
abstract::Hypersomnia is common in psychiatric disorders, yet there are few self-report measures that adequately characterize this sleep disturbance. The objective of this study was to validate the Hypersomnia Severity Index (HSI), a tool designed to measure severity, distress and impairment of hypersomnia in psychiatric popula...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112547
更新日期:2019-11-01 00:00:00
abstract::The current paper evaluates Criterion B for Non-Suicidal Self-Injury Disorder, which states that non-suicidal self-injury (NSSI) must occur for at least one function. The majority of individuals who engage in NSSI report at least one function, so it is unclear if Criterion B provides diagnostic utility in individuals ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.07.025
更新日期:2016-10-30 00:00:00
abstract::The objective of the study was to examine the relationship between an index of central dopamine function and electroretinographic (ERG) blue cone amplitudes in cocaine-dependent patients. Thus, 17 recently abstinent cocaine-dependent patients had an ERG performed. They also had a lumbar puncture for determination of c...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(02)00323-2
更新日期:2003-02-15 00:00:00
abstract::The reliability and validity of the Toronto Structured Interview for Alexithymia (TSIA) have been demonstrated in previous studies with English-speaking community and psychiatric samples and a German-speaking psychiatric sample. The aim of this study was to evaluate the psychometric properties of the TSIA in a mixed c...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.02.015
更新日期:2011-05-30 00:00:00