Abstract:
:Differences in antipsychotic treatment response, clinical course and outcome of schizophrenia could be related to gender-related cerebral differences in anatomy and function. The aim of the study was to assess sex differences in the striatal dopamine D2 receptor binding in 15 drug-naive schizophrenic patients (seven males, eight females) using (123)I-IBZM single photon emission computed tomography. Basal ganglia/frontal cortex (BG/FC) uptake ratios were obtained. No significant differences were found in global, left and right BG/FC ratios or laterality indices between males and females. No correlation was found between BG/FC ratios and age, duration of illness or scores on symptom rating scales. Our data indicate a lack of sex differences in striatal D2 receptor binding in drug-naive schizophrenic patients and do not support previous reports of left lateralized striatal asymmetry in male schizophrenic patients.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Parellada E,Lomeña F,Catafau AM,Bernardo M,Font M,Fernández-Egea E,Pavía J,Gutierrez Fdoi
10.1016/j.pscychresns.2003.05.001subject
Has Abstractpub_date
2004-01-15 00:00:00pages
79-84issue
1eissn
0165-1781issn
1872-7123pii
S0925492703001574journal_volume
130pub_type
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journal_title:Psychiatry research
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pub_type: 杂志文章,多中心研究
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journal_title:Psychiatry research
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pub_type: 杂志文章
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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更新日期:2003-08-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.07.003
更新日期:2004-10-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2003-10-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2003.12.021
更新日期:2004-04-30 00:00:00
abstract::Klinefelter syndrome (47, XXY) is a sex chromosome aneuploidy associated with mild deficits in cognitive and language functions. Dysfunctions have also been reported in performance of tasks which examine executive functions. However, it is unclear whether the impaired performance is caused or accentuated by problems w...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.02.028
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pub_type: 杂志文章,评审
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更新日期:2014-12-15 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-10-30 00:00:00
abstract::A non-clinical sample of male Australian Vietnam veterans, their wives, and adult offspring were interviewed in-person in a national epidemiological study to assess the relationship between the mental ill-health of veterans and the emotional climate of the family while the children were growing up. Veterans were asses...
journal_title:Psychiatry research
pub_type: 杂志文章
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更新日期:2018-10-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2011.05.010
更新日期:2011-12-30 00:00:00
abstract::The aim of this study is to investigate whether mismatch negativity (MMN) is associated with functional status or is a state-independent trait for schizophrenia. We assessed MMN in 26 patients with schizophrenia, 20 healthy subjects with high genetic loading, and 48 healthy controls. Repeated measures analysis of vari...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.02.012
更新日期:2014-04-30 00:00:00